Planaria EST Database


DrC_00601

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00601
         (1091 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   286   5e-77
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   283   8e-76
sp|Q9GLE3|CATK_PIG  Cathepsin K precursor                         279   9e-75
sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   279   1e-74
sp|P25975|CATL_BOVIN  Cathepsin L precursor [Contains: Cathe...   279   1e-74
sp|P43236|CATK_RABIT  Cathepsin K precursor (OC-2 protein)        278   1e-74
sp|O35186|CATK_RAT  Cathepsin K precursor                         278   1e-74
sp|P43235|CATK_HUMAN  Cathepsin K precursor (Cathepsin O) (C...   277   3e-74
sp|P61277|CATK_MACMU  Cathepsin K precursor >gi|47117667|sp|...   277   3e-74
sp|P55097|CATK_MOUSE  Cathepsin K precursor                       277   4e-74
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  286 bits (733), Expect = 5e-77
 Identities = 151/326 (46%), Positives = 199/326 (61%), Gaps = 5/326 (1%)
 Frame = +2

Query: 8   VAVQSAPQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLG 187
           + + SA   F  D  L+ +W  +K    + Y    E  RR +WE N+K I+ HN EY  G
Sbjct: 12  LGIASAVPKF--DQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQG 69

Query: 188 KHSYTLAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVT 367
           KH +T+A+N F DMTNEEF+ + +     Q+   G  F  P  + DLP+SVDWRK+G+VT
Sbjct: 70  KHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFL-DLPKSVDWRKKGYVT 127

Query: 368 PVKNQKTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSF 547
           PVKNQK CGSC+AFSATG+LEGQ FRKT KLVS SEQ +VDCS   GN+GC GGF   +F
Sbjct: 128 PVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAF 187

Query: 548 DXXXXXXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPIS 724
                                  C+Y     +    GFT +    E+AL +AVA +GPIS
Sbjct: 188 QYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPIS 247

Query: 725 VRIDASRRSFIEYSGNGIYYDPNCDSDHLRHAVLVVGYG----SKDGKNFWIVKNSWGTT 892
           V +DA   SF ++  +GIY++P+C S +L H VLVVGYG    + +   +W+VKNSWG  
Sbjct: 248 VAMDAGHSSF-QFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPE 306

Query: 893 WGRKGYILMSKDEDNQCGIATEASYP 970
           WG  GY+ ++KD++N CGIAT ASYP
Sbjct: 307 WGSNGYVKIAKDKNNHCGIATAASYP 332
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  283 bits (723), Expect = 8e-76
 Identities = 152/328 (46%), Positives = 195/328 (59%), Gaps = 5/328 (1%)
 Frame = +2

Query: 8   VAVQSAPQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLG 187
           + + SA   F  D  LN +W  +K    + Y    E  RR +WE N+K I+ HN EY  G
Sbjct: 12  LGIASAAPKF--DQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNREYSQG 69

Query: 188 KHSYTLAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVT 367
           KH +T+A+N F DMTNEEF+ + +     Q++  G  F  P    ++P+SVDWR++G+VT
Sbjct: 70  KHGFTMAMNAFGDMTNEEFR-QVMNGFQNQKHKKGKMFQEPL-FAEIPKSVDWREKGYVT 127

Query: 368 PVKNQKTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSF 547
           PVKNQ  CGSC+AFSATG+LEGQ FRKT KLVS SEQ +VDCS   GN GC GG    +F
Sbjct: 128 PVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAF 187

Query: 548 D--XXXXXXXXXXXXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPI 721
                                   C Y          GF ++  R E+AL +AVA +GPI
Sbjct: 188 RYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQR-EKALMKAVATLGPI 246

Query: 722 SVRIDASRRSFIEYSGNGIYYDPNCDSDHLRHAVLVVGY---GSKDGKNFWIVKNSWGTT 892
           SV IDA  +SF ++  +GIY+DP+C S  L H VLVVGY   G+     FWIVKNSWG  
Sbjct: 247 SVAIDAGHQSF-QFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPE 305

Query: 893 WGRKGYILMSKDEDNQCGIATEASYPLI 976
           WG  GY+ M+KD++N CGIAT ASYP +
Sbjct: 306 WGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
          Length = 330

 Score =  279 bits (714), Expect = 9e-75
 Identities = 144/310 (46%), Positives = 198/310 (63%), Gaps = 4/310 (1%)
 Frame = +2

Query: 53  LNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLAVNQFTDM 229
           L+ +WE +K  + K+Y+  ++E+SRR+IWE NLK+I  HNLE  LG H+Y LA+N   DM
Sbjct: 23  LDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 82

Query: 230 TNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 403
           T+EE   K +T + +    + +  +  +P+     P S+D+RK+G+VTPVKNQ  CGSC+
Sbjct: 83  TSEEVVQK-MTGLKVPPSHSRSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCW 141

Query: 404 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXX 583
           AFS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+   +F            
Sbjct: 142 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSE 199

Query: 584 XXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 760
                      C YN +    K +G+  I   +E+AL +AVA +GP+SV IDAS  SF  
Sbjct: 200 DAYPYVGQDENCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 259

Query: 761 YSGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTTWGRKGYILMSKDEDNQ 940
           YS  G+YYD NC+SD+L HAVL VGYG + GK  WI+KNSWG  WG KGYILM+++++N 
Sbjct: 260 YS-KGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIKNSWGENWGNKGYILMARNKNNA 318

Query: 941 CGIATEASYP 970
           CGIA  AS+P
Sbjct: 319 CGIANLASFP 328
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  279 bits (713), Expect = 1e-74
 Identities = 145/323 (44%), Positives = 192/323 (59%), Gaps = 5/323 (1%)
 Frame = +2

Query: 23  APQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSYT 202
           A  + + D  L  +W  +K   N+ Y    E  RR +WE N+K I+ HN EY  GKHS+T
Sbjct: 15  ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFT 74

Query: 203 LAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQ 382
           +A+N F DMT+EEF+ + +     ++   G  F  P    + P+SVDWR++G+VTPVKNQ
Sbjct: 75  MAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQ 132

Query: 383 KTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXX 562
             CGSC+AFSATG+LEGQ FRKT +L+S SEQ +VDCS   GN GC GG    +F     
Sbjct: 133 GQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD 192

Query: 563 XXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDA 739
                             C+YN    +    GF +I  + E+AL +AVA +GPISV IDA
Sbjct: 193 NGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAVATVGPISVAIDA 251

Query: 740 SRRSFIEYSGNGIYYDPNCDSDHLRHAVLVVGYG----SKDGKNFWIVKNSWGTTWGRKG 907
              SF+ Y   GIY++P+C S+ + H VLVVGYG      D   +W+VKNSWG  WG  G
Sbjct: 252 GHESFLFYK-EGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGG 310

Query: 908 YILMSKDEDNQCGIATEASYPLI 976
           Y+ M+KD  N CGIA+ ASYP +
Sbjct: 311 YVKMAKDRRNHCGIASAASYPTV 333
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  279 bits (713), Expect = 1e-74
 Identities = 150/318 (47%), Positives = 187/318 (58%), Gaps = 6/318 (1%)
 Frame = +2

Query: 41  IDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLAVNQF 220
           +D  L+  W  +K    + Y    E  RR +WE N K I  HN EY  GKH++ +A+N F
Sbjct: 21  LDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQEYSEGKHAFRMAMNAF 80

Query: 221 TDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSC 400
            DMTNEEF+ + +     Q++  G  F  P  V D+P+SVDW K+G+VTPVKNQ  CGSC
Sbjct: 81  GDMTNEEFR-QVMNGFQNQKHKKGKLFHEPLLV-DVPKSVDWTKKGYVTPVKNQGQCGSC 138

Query: 401 YAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFD--XXXXXXXX 574
           +AFSATG+LEGQ FRKT KLVS SEQ +VDCS   GN+GC GG    +F           
Sbjct: 139 WAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMDNAFQYIKDNGGLDS 198

Query: 575 XXXXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSF 754
                        C Y          GF +I  R E+AL +AVA +GPISV IDA   SF
Sbjct: 199 EESYPYLATDTNSCNYKPECSAANDTGFVDIPQR-EKALMKAVATVGPISVAIDAGHTSF 257

Query: 755 IEYSGNGIYYDPNCDSDHLRHAVLVVGYG----SKDGKNFWIVKNSWGTTWGRKGYILMS 922
            ++  +GIYYDP+C    L H VLVVGYG      +   FWIVKNSWG  WG  GY+ M+
Sbjct: 258 -QFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGPEWGWNGYVKMA 316

Query: 923 KDEDNQCGIATEASYPLI 976
           KD++N CGIAT ASYP +
Sbjct: 317 KDQNNHCGIATAASYPTV 334
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
          Length = 329

 Score =  278 bits (712), Expect = 1e-74
 Identities = 143/310 (46%), Positives = 199/310 (64%), Gaps = 4/310 (1%)
 Frame = +2

Query: 53  LNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLAVNQFTDM 229
           L+ +WE +K  ++K+Y+  ++E+SRR+IWE NLK+I  HNLE  LG H+Y LA+N   DM
Sbjct: 22  LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 81

Query: 230 TNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 403
           T+EE   K +T + +   R+ +  +  +P+     P S+D+RK+G+VTPVKNQ  CGSC+
Sbjct: 82  TSEEVVQK-MTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCW 140

Query: 404 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXX 583
           AFS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+   +F            
Sbjct: 141 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NYGCGGGYMTNAFQYVQRNRGIDSE 198

Query: 584 XXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 760
                      C YN +    K +G+  I   +E+AL +AVA +GP+SV IDAS  SF  
Sbjct: 199 DAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258

Query: 761 YSGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTTWGRKGYILMSKDEDNQ 940
           YS  G+YYD NC SD++ HAVL VGYG + G   WI+KNSWG +WG KGYILM+++++N 
Sbjct: 259 YS-KGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNA 317

Query: 941 CGIATEASYP 970
           CGIA  AS+P
Sbjct: 318 CGIANLASFP 327
>sp|O35186|CATK_RAT Cathepsin K precursor
          Length = 329

 Score =  278 bits (712), Expect = 1e-74
 Identities = 143/317 (45%), Positives = 201/317 (63%), Gaps = 4/317 (1%)
 Frame = +2

Query: 32  SFSIDTKLNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLA 208
           + S +  L+ +WE +K    K+Y+  ++E+SRR+IWE NLK I  HNLE  LG H+Y LA
Sbjct: 15  ALSPEETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEASLGAHTYELA 74

Query: 209 VNQFTDMTNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQ 382
           +N   DMT+EE   K +T + +   R+ +  +   PE    +P S+D+RK+G+VTPVKNQ
Sbjct: 75  MNHLGDMTSEEVVQK-MTGLRVPPSRSFSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQ 133

Query: 383 KTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXX 562
             CGSC+AFS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+   +F     
Sbjct: 134 GQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSE--NYGCGGGYMTTAFQYVQQ 191

Query: 563 XXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDA 739
                             C YN +    K +G+  I   +E+AL +AVA +GP+SV IDA
Sbjct: 192 NGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPVSVSIDA 251

Query: 740 SRRSFIEYSGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTTWGRKGYILM 919
           S  SF  YS  G+YYD NCD D++ HAVLVVGYG++ G  +WI+KNSWG +WG KGY+L+
Sbjct: 252 SLTSFQFYS-RGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWGNKGYVLL 310

Query: 920 SKDEDNQCGIATEASYP 970
           +++++N CGI   AS+P
Sbjct: 311 ARNKNNACGITNLASFP 327
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
          Length = 329

 Score =  277 bits (709), Expect = 3e-74
 Identities = 144/309 (46%), Positives = 193/309 (62%), Gaps = 3/309 (0%)
 Frame = +2

Query: 53  LNDEWEAYKLKFNKKYD-PLNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLAVNQFTDM 229
           L+  WE +K    K+Y+  ++E+SRR+IWE NLKYI  HNLE  LG H+Y LA+N   DM
Sbjct: 22  LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81

Query: 230 TNEEFKAKYL-TNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCYA 406
           T+EE   K     + +  + +  +  +PE     P SVD+RK+G+VTPVKNQ  CGSC+A
Sbjct: 82  TSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWA 141

Query: 407 FSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXXX 586
           FS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+   +F             
Sbjct: 142 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSED 199

Query: 587 XXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIEY 763
                     C YN +    K +G+  I   +E+AL +AVA +GP+SV IDAS  SF  Y
Sbjct: 200 AYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259

Query: 764 SGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTTWGRKGYILMSKDEDNQC 943
           S  G+YYD +C+SD+L HAVL VGYG + G   WI+KNSWG  WG KGYILM+++++N C
Sbjct: 260 S-KGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNAC 318

Query: 944 GIATEASYP 970
           GIA  AS+P
Sbjct: 319 GIANLASFP 327
>sp|P61277|CATK_MACMU Cathepsin K precursor
 sp|P61276|CATK_MACFA Cathepsin K precursor
          Length = 329

 Score =  277 bits (709), Expect = 3e-74
 Identities = 146/310 (47%), Positives = 196/310 (63%), Gaps = 4/310 (1%)
 Frame = +2

Query: 53  LNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSYTLAVNQFTDM 229
           L+  WE +K    K+Y+  ++E+SRR+IWE NLKYI  HNLE  LG H+Y LA+N   DM
Sbjct: 22  LDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81

Query: 230 TNEEFKAKYLTNISIQRNSTGSS--FIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 403
           TNEE   K +T + +  + + S+    +P+     P SVD+RK+G+VTPVKNQ  CGSC+
Sbjct: 82  TNEEVVQK-MTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCW 140

Query: 404 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXX 583
           AFS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+   +F            
Sbjct: 141 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSE 198

Query: 584 XXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 760
                      C YN +    K +G+  I   +E+AL +AVA +GP+SV IDAS  SF  
Sbjct: 199 DAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258

Query: 761 YSGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTTWGRKGYILMSKDEDNQ 940
           YS  G+YYD +C+SD+L HAVL VGYG + G   WI+KNSWG  WG KGYILM+++++N 
Sbjct: 259 YS-KGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNA 317

Query: 941 CGIATEASYP 970
           CGIA  AS+P
Sbjct: 318 CGIANLASFP 327
>sp|P55097|CATK_MOUSE Cathepsin K precursor
          Length = 329

 Score =  277 bits (708), Expect = 4e-74
 Identities = 146/326 (44%), Positives = 202/326 (61%), Gaps = 4/326 (1%)
 Frame = +2

Query: 5   FVAVQSAPQSFSIDTKLNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYD 181
           F+ +     + S +  L+ +WE +K    K+Y+  ++E+SRR+IWE NLK I  HNLE  
Sbjct: 6   FLLLPMVSFALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEAS 65

Query: 182 LGKHSYTLAVNQFTDMTNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKR 355
           LG H+Y LA+N   DMT+EE   K +T + I   R+ +  +   PE    +P S+D+RK+
Sbjct: 66  LGVHTYELAMNHLGDMTSEEVVQK-MTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKK 124

Query: 356 GFVTPVKNQKTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFS 535
           G+VTPVKNQ  CGSC+AFS+ G+LEGQ  +KT KL++ S Q +VDC  E  N GCGGG+ 
Sbjct: 125 GYVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE--NYGCGGGYM 182

Query: 536 KLSFDXXXXXXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYI 712
             +F                       C YN +    K +G+  I   +E+AL +AVA +
Sbjct: 183 TTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARV 242

Query: 713 GPISVRIDASRRSFIEYSGNGIYYDPNCDSDHLRHAVLVVGYGSKDGKNFWIVKNSWGTT 892
           GPISV IDAS  SF  YS  G+YYD NCD D++ HAVLVVGYG++ G   WI+KNSWG +
Sbjct: 243 GPISVSIDASLASFQFYS-RGVYYDENCDRDNVNHAVLVVGYGTQKGSKHWIIKNSWGES 301

Query: 893 WGRKGYILMSKDEDNQCGIATEASYP 970
           WG KGY L++++++N CGI   AS+P
Sbjct: 302 WGNKGYALLARNKNNACGITNMASFP 327
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 118,781,413
Number of Sequences: 369166
Number of extensions: 2438222
Number of successful extensions: 7409
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6470
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6926
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11963829660
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00601

  1. Dr_sW_015_L06
  2. Dr_sW_007_D17
  3. Dr_sW_003_I18