Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_D17
(820 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 224 2e-58
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 217 3e-56
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 217 4e-56
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 213 4e-55
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 212 1e-54
sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein) 210 3e-54
sp|P55097|CATK_MOUSE Cathepsin K precursor 210 4e-54
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 210 4e-54
sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (C... 209 6e-54
sp|P61277|CATK_MACMU Cathepsin K precursor >gi|47117667|sp|... 209 6e-54
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 224 bits (572), Expect = 2e-58
Identities = 124/274 (45%), Positives = 162/274 (59%), Gaps = 1/274 (0%)
Frame = +2
Query: 2 VAVQSAPQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLG 181
+ + SA F D L+ +W +K + Y E RR +WE N+K I+ HN EY G
Sbjct: 12 LGIASAVPKF--DQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQG 69
Query: 182 KHSFTLAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVT 361
KH FT+A+N F DMTNEEF+ + + Q+ G F P + DLP+SVDWRK+G+VT
Sbjct: 70 KHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFL-DLPKSVDWRKKGYVT 127
Query: 362 PVKNQKTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSF 541
PVKNQK CGSC+AFSATG+LEGQ FRKT KLVS SEQ +VDCS GN+GC GGF +F
Sbjct: 128 PVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAF 187
Query: 542 DXXXXXXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPIS 718
C+Y + GFT + E+AL +AVA +GPIS
Sbjct: 188 QYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPIS 247
Query: 719 VRIDASRRSFIEYSGNGIYYDPNCDSDHLRHAVL 820
V +DA SF ++ +GIY++P+C S +L H VL
Sbjct: 248 VAMDAGHSSF-QFYKSGIYFEPDCSSKNLDHGVL 280
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 217 bits (553), Expect = 3e-56
Identities = 122/275 (44%), Positives = 158/275 (57%), Gaps = 2/275 (0%)
Frame = +2
Query: 2 VAVQSAPQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLG 181
+ + SA F D LN +W +K + Y E RR +WE N+K I+ HN EY G
Sbjct: 12 LGIASAAPKF--DQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNREYSQG 69
Query: 182 KHSFTLAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVT 361
KH FT+A+N F DMTNEEF+ + + Q++ G F P ++P+SVDWR++G+VT
Sbjct: 70 KHGFTMAMNAFGDMTNEEFR-QVMNGFQNQKHKKGKMFQEPL-FAEIPKSVDWREKGYVT 127
Query: 362 PVKNQKTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSF 541
PVKNQ CGSC+AFSATG+LEGQ FRKT KLVS SEQ +VDCS GN GC GG +F
Sbjct: 128 PVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAF 187
Query: 542 D--XXXXXXXXXXXXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPI 715
C Y GF ++ R E+AL +AVA +GPI
Sbjct: 188 RYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQR-EKALMKAVATLGPI 246
Query: 716 SVRIDASRRSFIEYSGNGIYYDPNCDSDHLRHAVL 820
SV IDA +SF ++ +GIY+DP+C S L H VL
Sbjct: 247 SVAIDAGHQSF-QFYKSGIYFDPDCSSKDLDHGVL 280
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 217 bits (552), Expect = 4e-56
Identities = 117/269 (43%), Positives = 157/269 (58%), Gaps = 1/269 (0%)
Frame = +2
Query: 17 APQSFSIDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSFT 196
A + + D L +W +K N+ Y E RR +WE N+K I+ HN EY GKHSFT
Sbjct: 15 ASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFT 74
Query: 197 LAVNQFTDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQ 376
+A+N F DMT+EEF+ + + ++ G F P + P+SVDWR++G+VTPVKNQ
Sbjct: 75 MAMNAFGDMTSEEFR-QVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQ 132
Query: 377 KTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXX 556
CGSC+AFSATG+LEGQ FRKT +L+S SEQ +VDCS GN GC GG +F
Sbjct: 133 GQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD 192
Query: 557 XXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDA 733
C+YN + GF +I + E+AL +AVA +GPISV IDA
Sbjct: 193 NGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDI-PKQEKALMKAVATVGPISVAIDA 251
Query: 734 SRRSFIEYSGNGIYYDPNCDSDHLRHAVL 820
SF+ Y GIY++P+C S+ + H VL
Sbjct: 252 GHESFLFYK-EGIYFEPDCSSEDMDHGVL 279
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 213 bits (543), Expect = 4e-55
Identities = 120/264 (45%), Positives = 150/264 (56%), Gaps = 2/264 (0%)
Frame = +2
Query: 35 IDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQF 214
+D L+ W +K + Y E RR +WE N K I HN EY GKH+F +A+N F
Sbjct: 21 LDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQEYSEGKHAFRMAMNAF 80
Query: 215 TDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSC 394
DMTNEEF+ + + Q++ G F P V D+P+SVDW K+G+VTPVKNQ CGSC
Sbjct: 81 GDMTNEEFR-QVMNGFQNQKHKKGKLFHEPLLV-DVPKSVDWTKKGYVTPVKNQGQCGSC 138
Query: 395 YAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFD--XXXXXXXX 568
+AFSATG+LEGQ FRKT KLVS SEQ +VDCS GN+GC GG +F
Sbjct: 139 WAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMDNAFQYIKDNGGLDS 198
Query: 569 XXXXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSF 748
C Y GF +I R E+AL +AVA +GPISV IDA SF
Sbjct: 199 EESYPYLATDTNSCNYKPECSAANDTGFVDIPQR-EKALMKAVATVGPISVAIDAGHTSF 257
Query: 749 IEYSGNGIYYDPNCDSDHLRHAVL 820
++ +GIYYDP+C L H VL
Sbjct: 258 -QFYKSGIYYDPDCSCKDLDHGVL 280
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 212 bits (539), Expect = 1e-54
Identities = 118/264 (44%), Positives = 153/264 (57%), Gaps = 2/264 (0%)
Frame = +2
Query: 35 IDTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQF 214
+D L+ +W +K + Y E RR +WE N+K I+ HN EY GKH F++A+N F
Sbjct: 21 LDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAF 80
Query: 215 TDMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSC 394
DMTNEEF+ + + Q++ G F V ++P+SVDWR++G+VT VKNQ CGSC
Sbjct: 81 GDMTNEEFR-QVMNGFQNQKHKKGKVFH-ESLVLEVPKSVDWREKGYVTAVKNQGQCGSC 138
Query: 395 YAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFD--XXXXXXXX 568
+AFSATG+LEGQ FRKT KLVS SEQ +VDCS GN+GC GG +F
Sbjct: 139 WAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDT 198
Query: 569 XXXXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSF 748
C Y GF +I R E+AL +AVA +GPISV IDA SF
Sbjct: 199 EESYPYLGRETNSCTYKPECSAANDTGFVDIPQR-EKALMKAVATVGPISVAIDAGHSSF 257
Query: 749 IEYSGNGIYYDPNCDSDHLRHAVL 820
++ +GIYYDP+C S L H VL
Sbjct: 258 -QFYKSGIYYDPDCSSKDLDHGVL 280
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
Length = 329
Score = 210 bits (535), Expect = 3e-54
Identities = 114/262 (43%), Positives = 162/262 (61%), Gaps = 4/262 (1%)
Frame = +2
Query: 47 LNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQFTDM 223
L+ +WE +K ++K+Y+ ++E+SRR+IWE NLK+I HNLE LG H++ LA+N DM
Sbjct: 22 LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 81
Query: 224 TNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 397
T+EE K +T + + R+ + + +P+ P S+D+RK+G+VTPVKNQ CGSC+
Sbjct: 82 TSEEVVQK-MTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCW 140
Query: 398 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXX 577
AFS+ G+LEGQ +KT KL++ S Q +VDC E N GCGGG+ +F
Sbjct: 141 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NYGCGGGYMTNAFQYVQRNRGIDSE 198
Query: 578 XXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 754
C YN + K +G+ I +E+AL +AVA +GP+SV IDAS SF
Sbjct: 199 DAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258
Query: 755 YSGNGIYYDPNCDSDHLRHAVL 820
YS G+YYD NC SD++ HAVL
Sbjct: 259 YS-KGVYYDENCSSDNVNHAVL 279
>sp|P55097|CATK_MOUSE Cathepsin K precursor
Length = 329
Score = 210 bits (534), Expect = 4e-54
Identities = 118/269 (43%), Positives = 162/269 (60%), Gaps = 4/269 (1%)
Frame = +2
Query: 26 SFSIDTKLNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLA 202
+ S + L+ +WE +K K+Y+ ++E+SRR+IWE NLK I HNLE LG H++ LA
Sbjct: 15 ALSPEEMLDTQWELWKKTHQKQYNSKVDEISRRLIWEKNLKQISAHNLEASLGVHTYELA 74
Query: 203 VNQFTDMTNEEFKAKYLTNISI--QRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQ 376
+N DMT+EE K +T + I R+ + + PE +P S+D+RK+G+VTPVKNQ
Sbjct: 75 MNHLGDMTSEEVVQK-MTGLRIPPSRSYSNDTLYTPEWEGRVPDSIDYRKKGYVTPVKNQ 133
Query: 377 KTCGSCYAFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXX 556
CGSC+AFS+ G+LEGQ +KT KL++ S Q +VDC E N GCGGG+ +F
Sbjct: 134 GQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVTE--NYGCGGGYMTTAFQYVQQ 191
Query: 557 XXXXXXXXXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDA 733
C YN + K +G+ I +E+AL +AVA +GPISV IDA
Sbjct: 192 NGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVGPISVSIDA 251
Query: 734 SRRSFIEYSGNGIYYDPNCDSDHLRHAVL 820
S SF YS G+YYD NCD D++ HAVL
Sbjct: 252 SLASFQFYS-RGVYYDENCDRDNVNHAVL 279
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 210 bits (534), Expect = 4e-54
Identities = 113/262 (43%), Positives = 153/262 (58%), Gaps = 1/262 (0%)
Frame = +2
Query: 38 DTKLNDEWEAYKLKFNKKYDPLNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQFT 217
D N +W +K + Y E RR +WE N++ IQ HN EY GKH FT+ +N F
Sbjct: 22 DQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFG 81
Query: 218 DMTNEEFKAKYLTNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 397
DMTNEEF+ + + Q++ G F P ++ +P++VDWR++G VTPVKNQ CGSC+
Sbjct: 82 DMTNEEFR-QIVNGYRHQKHKKGRLFQEPLMLQ-IPKTVDWREKGCVTPVKNQGQCGSCW 139
Query: 398 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFD-XXXXXXXXXX 574
AFSA+G LEGQ F KT KL+S SEQ +VDCS + GN+GC GG +F
Sbjct: 140 AFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSE 199
Query: 575 XXXXXXXXXXRCRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 754
C+Y + GF +I + E+AL +AVA +GPISV +DAS S ++
Sbjct: 200 ESYPYEAKDGSCKYRAEYAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPS-LQ 257
Query: 755 YSGNGIYYDPNCDSDHLRHAVL 820
+ +GIYY+PNC S L H VL
Sbjct: 258 FYSSGIYYEPNCSSKDLDHGVL 279
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
Length = 329
Score = 209 bits (533), Expect = 6e-54
Identities = 115/261 (44%), Positives = 157/261 (60%), Gaps = 3/261 (1%)
Frame = +2
Query: 47 LNDEWEAYKLKFNKKYD-PLNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQFTDM 223
L+ WE +K K+Y+ ++E+SRR+IWE NLKYI HNLE LG H++ LA+N DM
Sbjct: 22 LDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81
Query: 224 TNEEFKAKYL-TNISIQRNSTGSSFIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCYA 400
T+EE K + + + + + +PE P SVD+RK+G+VTPVKNQ CGSC+A
Sbjct: 82 TSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWA 141
Query: 401 FSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXXX 580
FS+ G+LEGQ +KT KL++ S Q +VDC E N GCGGG+ +F
Sbjct: 142 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSED 199
Query: 581 XXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIEY 757
C YN + K +G+ I +E+AL +AVA +GP+SV IDAS SF Y
Sbjct: 200 AYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259
Query: 758 SGNGIYYDPNCDSDHLRHAVL 820
S G+YYD +C+SD+L HAVL
Sbjct: 260 S-KGVYYDESCNSDNLNHAVL 279
>sp|P61277|CATK_MACMU Cathepsin K precursor
sp|P61276|CATK_MACFA Cathepsin K precursor
Length = 329
Score = 209 bits (533), Expect = 6e-54
Identities = 117/262 (44%), Positives = 160/262 (61%), Gaps = 4/262 (1%)
Frame = +2
Query: 47 LNDEWEAYKLKFNKKYDP-LNELSRRMIWEDNLKYIQQHNLEYDLGKHSFTLAVNQFTDM 223
L+ WE +K K+Y+ ++E+SRR+IWE NLKYI HNLE LG H++ LA+N DM
Sbjct: 22 LDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81
Query: 224 TNEEFKAKYLTNISIQRNSTGSS--FIVPENVKDLPQSVDWRKRGFVTPVKNQKTCGSCY 397
TNEE K +T + + + + S+ +P+ P SVD+RK+G+VTPVKNQ CGSC+
Sbjct: 82 TNEEVVQK-MTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCW 140
Query: 398 AFSATGSLEGQYFRKTKKLVSFSEQQIVDCSEEFGNRGCGGGFSKLSFDXXXXXXXXXXX 577
AFS+ G+LEGQ +KT KL++ S Q +VDC E N GCGGG+ +F
Sbjct: 141 AFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRGIDSE 198
Query: 578 XXXXXXXXXR-CRYNKSKVIVKSKGFTNIRSRDEEALAQAVAYIGPISVRIDASRRSFIE 754
C YN + K +G+ I +E+AL +AVA +GP+SV IDAS SF
Sbjct: 199 DAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQF 258
Query: 755 YSGNGIYYDPNCDSDHLRHAVL 820
YS G+YYD +C+SD+L HAVL
Sbjct: 259 YS-KGVYYDESCNSDNLNHAVL 279
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,360,756
Number of Sequences: 369166
Number of extensions: 1829815
Number of successful extensions: 5626
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5016
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5336
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7859674995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)