Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00536 (921 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex sub... 233 4e-61 sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 co... 233 4e-61 sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 co... 231 2e-60 sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 co... 226 7e-59 sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex sub... 160 6e-39 sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex sub... 135 1e-31 sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC) 129 9e-30 sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC) 98 3e-20 sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropi... 32 2.5 sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropi... 32 2.5
>sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) sp|Q5R5Z5|ARPC2_PONPY Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 300 Score = 233 bits (595), Expect = 4e-61 Identities = 121/214 (56%), Positives = 156/214 (72%), Gaps = 2/214 (0%) Frame = +3 Query: 54 NKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSITLKFFKEL 230 N+ ++E L KF A +G K E ++ ADFDG +Y I+N DK + VSI+LKF+KEL Sbjct: 8 NRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKEL 67 Query: 231 QEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFE 410 Q +GAD++LKR YG L N PE G NV++ YDL LP + + + H A +LKRNCFASVFE Sbjct: 68 QAHGADELLKRVYGSFLVN-PESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFE 126 Query: 411 MFFDYQESGNTNK-QAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELT 587 +F +QE G + +A+I+YRDDETMYV++ +DRVTVVFSTVFKD DDV+IGKVF+QE Sbjct: 127 KYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFK 186 Query: 588 EARRRVDRAPQVLYSPKEPPIELKGTKAATGDNV 689 E RR APQVL+S +EPP+ELK T AA GDN+ Sbjct: 187 EGRRASHTAPQVLFSHREPPLELKDTDAAVGDNI 220
Score = 95.9 bits (237), Expect = 1e-19 Identities = 45/63 (71%), Positives = 54/63 (85%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 YITFVLF RH +AR N+I+LIHTFR+YLHYHIKCSKAYIH RMRAK+ +FLK+L RA Sbjct: 222 YITFVLFPRH-TNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRA 280 Query: 874 KPE 882 +P+ Sbjct: 281 RPD 283
>sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 301 Score = 233 bits (595), Expect = 4e-61 Identities = 119/214 (55%), Positives = 159/214 (74%), Gaps = 2/214 (0%) Frame = +3 Query: 54 NKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSITLKFFKEL 230 N+ ++E LL K+ A++G K E + +ADFDG +Y I+N DK + +SI+LKF+K+L Sbjct: 8 NRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYKQL 67 Query: 231 QEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFE 410 QE+GAD++LKREYG L D E G NV++ +L ++P++ E++A LLKRNCFASVFE Sbjct: 68 QEHGADELLKREYGS-LLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRNCFASVFE 126 Query: 411 MFFDYQESGNTN-KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELT 587 +FDYQE G K+A+INYR+DET+YV+A DRVTVVFST+F+D DDVIIGKVF+QEL Sbjct: 127 KYFDYQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELR 186 Query: 588 EARRRVDRAPQVLYSPKEPPIELKGTKAATGDNV 689 E RR APQVL+S +EPP+EL T A GDN+ Sbjct: 187 EGRRASHTAPQVLFSHREPPLELANTDARVGDNI 220
Score = 92.0 bits (227), Expect = 2e-18 Identities = 43/63 (68%), Positives = 51/63 (80%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 Y+TFVLF RH R N+I+LIH FR+YLHYHIKCSKAYIH RMRAK+ +FLK+L RA Sbjct: 222 YVTFVLFPRH-TNKETRDNTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRA 280 Query: 874 KPE 882 +PE Sbjct: 281 RPE 283
>sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 301 Score = 231 bits (589), Expect = 2e-60 Identities = 119/215 (55%), Positives = 157/215 (73%), Gaps = 3/215 (1%) Frame = +3 Query: 54 NKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSITLKFFKEL 230 N+ + E+L QKF AK G K E + ADFDG +YK++N + D+ I +SI+LKF+ EL Sbjct: 8 NRIIVELLEQKFANAKEGGKPESVNVTFADFDGVLYKLSNPDGDRTKIILSISLKFYTEL 67 Query: 231 QEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFE 410 Q++GAD +L+R YG + + PE G NVT++Y+L LP + +L A+ LKRNCFASVFE Sbjct: 68 QQHGADDLLRRVYGGHMRSTPEQGFNVTLEYNLADLPADTTDLVQAASALKRNCFASVFE 127 Query: 411 MFFDYQESGNT-NKQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELT 587 +F++QE+G +K+A+INYRDDETMY++A DRVTV+FSTVFKDADDVIIGKVF+QE Sbjct: 128 KYFEFQEAGQEGHKRAVINYRDDETMYIEAKADRVTVIFSTVFKDADDVIIGKVFLQEFR 187 Query: 588 EARRRVDRAPQVLYSPKEPPIELKG-TKAATGDNV 689 E R+ AP VLYS EPP+ELK +A GDNV Sbjct: 188 EGRKASQTAPAVLYSLGEPPLELKDLPEARVGDNV 222
Score = 91.7 bits (226), Expect = 3e-18 Identities = 42/65 (64%), Positives = 52/65 (80%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 YITFVLF RH + N+IDLIH+FR+YLHYHIKCSK Y+H RMRAK+ +FLK+L RA Sbjct: 224 YITFVLFPRH-TNKKTKDNTIDLIHSFRDYLHYHIKCSKVYLHTRMRAKTTDFLKVLNRA 282 Query: 874 KPEYR 888 +PE + Sbjct: 283 RPEVK 287
>sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 304 Score = 226 bits (576), Expect = 7e-59 Identities = 118/217 (54%), Positives = 153/217 (70%), Gaps = 5/217 (2%) Frame = +3 Query: 54 NKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSITLKFFKEL 230 N+ V+E L KF A +G K E + +ADFDG ++ I+N DK + SI+LKF+K+L Sbjct: 8 NRIVEETLTVKFKNAIAGNKAESIDVTVADFDGVLFHISNINGDKTKVRTSISLKFYKQL 67 Query: 231 QEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFE 410 QE+GAD++LKREYGD L PE G NV++ DL +P+N EE LLKRNCFASVFE Sbjct: 68 QEHGADELLKREYGDLLVA-PEDGYNVSVLVDLENIPENWEETVRKIGLLKRNCFASVFE 126 Query: 411 MFFDYQESGNTN----KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQ 578 +FD+Q G K+A+INYR+DETMYV+A DRVTVVFST+F+D DDV++GKVF+Q Sbjct: 127 KYFDFQSQGEGEGEGQKRAVINYRNDETMYVEAKPDRVTVVFSTIFRDEDDVVLGKVFMQ 186 Query: 579 ELTEARRRVDRAPQVLYSPKEPPIELKGTKAATGDNV 689 EL E RR APQVL+S +EPP+EL T A G+N+ Sbjct: 187 ELREGRRASHTAPQVLFSHREPPLELANTGARVGENI 223
Score = 92.0 bits (227), Expect = 2e-18 Identities = 44/63 (69%), Positives = 51/63 (80%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 Y+TFVLF RH A R N+I+LIH FR+YLHYHIKCSKAYIH RMRAK+ FLK+L RA Sbjct: 225 YVTFVLFPRHTAKET-RDNTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTTEFLKVLNRA 283 Query: 874 KPE 882 +PE Sbjct: 284 RPE 286
>sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 191 Score = 160 bits (404), Expect = 6e-39 Identities = 77/127 (60%), Positives = 98/127 (77%), Gaps = 1/127 (0%) Frame = +3 Query: 312 TIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFFDYQESGNTNK-QAIINYRDDETMY 488 ++ YDL LP + + + H A +LKRNCFASVFE +F +QE G + +A+I+YRDDETMY Sbjct: 1 SLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMY 60 Query: 489 VKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRRVDRAPQVLYSPKEPPIELKGTK 668 V++ +DRVTVVFSTVFKD DDV+IGKVF+QE E RR APQVL+S +EPP+ELK T Sbjct: 61 VESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTD 120 Query: 669 AATGDNV 689 AA GDN+ Sbjct: 121 AAVGDNI 127
Score = 95.5 bits (236), Expect = 2e-19 Identities = 45/63 (71%), Positives = 53/63 (84%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 YITFVLF RH AR N+I+LIHTFR+YLHYHIKCSKAYIH RMRAK+ +FLK+L RA Sbjct: 129 YITFVLFPRH-TNATARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRA 187 Query: 874 KPE 882 +P+ Sbjct: 188 RPD 190
>sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa subunit) (p34-ARC) Length = 293 Score = 135 bits (341), Expect = 1e-31 Identities = 73/184 (39%), Positives = 105/184 (57%), Gaps = 1/184 (0%) Frame = +3 Query: 120 KMKQCLADFDGAIYKITNEKDKNIIYVSITLKFFKELQEYGADKVLKREYGDRLCNDPEP 299 ++ ADFDG + + DK+ + VS++L +L + G +LK YGD L PE Sbjct: 24 RVNNIFADFDGVKFNVQTSDDKSSLMVSVSLHAAADLLKNGGSALLKSVYGDMLQAKPEG 83 Query: 300 GSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFFDYQESGNTNKQAI-INYRDD 476 G +VT+ + N EELA +LLKR+ A+ F M F+ E+ + I INYR D Sbjct: 84 GYDVTLVIQ-SSFSGNKEELAKKVSLLKRHLVAAPFLMVFEGIEAKKPLPEIIAINYRTD 142 Query: 477 ETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRRVDRAPQVLYSPKEPPIEL 656 ET Y+K D V V+F FKDADDVI+ K+F+Q + R+ + P + +S K+PP+EL Sbjct: 143 ETFYLKPQGDNVIVIFDIAFKDADDVILSKIFLQSFVDVRKTISNVPSITFSQKDPPLEL 202 Query: 657 KGTK 668 KG K Sbjct: 203 KGVK 206
Score = 73.2 bits (178), Expect = 1e-12 Identities = 33/63 (52%), Positives = 45/63 (71%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 +++FVLF H P + S DLI TFR+YLHYHIKC+K Y+H MR + E+ +++L RA Sbjct: 217 FVSFVLFPAHIKKP---QESADLIQTFRDYLHYHIKCAKGYMHTSMRNRVESLIQVLNRA 273 Query: 874 KPE 882 KPE Sbjct: 274 KPE 276
>sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC) Length = 317 Score = 129 bits (325), Expect = 9e-30 Identities = 82/222 (36%), Positives = 128/222 (57%), Gaps = 23/222 (10%) Frame = +3 Query: 63 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFFKELQEYG 242 + E+L ++F S + Q + DFDG + I+ ++K I +S+++K + EL YG Sbjct: 11 IYELLTERF----SSENPSSIDQVVTDFDGVTFHISTPEEKTKILISLSMKCYPELVNYG 66 Query: 243 ADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLP---DNIEELAHNAALLKRNCFASVFEM 413 +LK+ YG + ++PE G N +I DL +LP + E+LA + ++LKRN A+ F Sbjct: 67 TLDLLKQIYGAYV-HEPEMGYNFSILIDLQQLPATDEEKEQLAMSISMLKRNVLAAPFHR 125 Query: 414 FF------------DYQESGNTNKQAI------INYRDDETMYVKAMEDRVTVVFSTVFK 539 F D + + +KQA I+YRD+ET+ + DRVTVVFST F+ Sbjct: 126 AFTKQAELADLARKDPENAPMLDKQATSQELMAIHYRDEETIVLWPEHDRVTVVFSTKFR 185 Query: 540 DADDVIIGKVFIQELTEARRR--VDRAPQVLYSPKEPPIELK 659 + D I GKVF+QE +ARRR + APQVL+S ++PP+E++ Sbjct: 186 EETDRIFGKVFLQEFVDARRRPAIQTAPQVLFSYRDPPLEIR 227
Score = 75.9 bits (185), Expect = 2e-13 Identities = 36/63 (57%), Positives = 46/63 (73%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 ++TFVLF RHF TP R++ I I FRN LH+HIK SKAY+H RMR + +F K+L RA Sbjct: 240 FVTFVLFERHF-TPQNREDCISHIQVFRNTLHFHIKASKAYMHQRMRKRVADFQKVLNRA 298 Query: 874 KPE 882 KP+ Sbjct: 299 KPD 301
>sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC) Length = 342 Score = 98.2 bits (243), Expect = 3e-20 Identities = 73/233 (31%), Positives = 119/233 (51%), Gaps = 34/233 (14%) Frame = +3 Query: 63 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNE-KDKNIIYVSITLKFFKELQEY 239 +++ L + A + G+ + M + ++DFD Y I+N +DK+I+ +S+ K + + E Sbjct: 11 IQKTLNEAIEALRKGSPLT-MDRIVSDFDYTTYHISNTAEDKSILLLSVKTKAWVSVSEC 69 Query: 240 GAD------KVLKREY----GDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 389 D K L Y G + ++ EPG + T+Q L +L ++E ++LK Sbjct: 70 QLDGSLTLLKFLADHYSSLGGVTIPSEVEPGYDYTLQITLAEL---VQESILQLSVLKTI 126 Query: 390 CFASVFEM----FFDYQE----------------SGNTNKQAIINYRDDETMYVKAMEDR 509 + FE+ F + + + N I YRD+E +++K DR Sbjct: 127 ILSFPFELAISKFIELSQQQPAPVEAEITGGEVAANGDNTLFTIKYRDEENIFIKPSNDR 186 Query: 510 VTVVFSTVFKDADDVIIGKVFIQELTEARRR---VDRAPQVLYSPKEPPIELK 659 VT++F T+F+D D I GKVF+QE +AR+R + APQVLYS EPP+ELK Sbjct: 187 VTIIFETIFQDETDKIFGKVFLQEFVDARKRNRQIQSAPQVLYS-HEPPLELK 238
Score = 78.6 bits (192), Expect = 2e-14 Identities = 36/61 (59%), Positives = 46/61 (75%) Frame = +1 Query: 694 YITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRA 873 +ITFVLF RHF T + +SI + FRNY HYHIKCSKAY+H RMR + ++F+K+L RA Sbjct: 253 FITFVLFPRHFQTKELQFHSICQLTLFRNYFHYHIKCSKAYMHSRMRFRVDSFIKVLNRA 312 Query: 874 K 876 K Sbjct: 313 K 313
>sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropic repressor codY Length = 257 Score = 32.0 bits (71), Expect = 2.5 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Frame = +3 Query: 114 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 263 ++K K DF I+N N+ VS K + +++ D+ + R Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73 Query: 264 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 371 EY + L N + SN+ I +LT P E+ N+ Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
>sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropic repressor codY Length = 256 Score = 32.0 bits (71), Expect = 2.5 Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%) Frame = +3 Query: 114 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 263 ++K K DF I+N N+ VS K + +++ D+ + R Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73 Query: 264 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 371 EY + L N + SN+ I +LT P E+ N+ Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,067,189 Number of Sequences: 369166 Number of extensions: 1696280 Number of successful extensions: 5156 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4958 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5131 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9414689480 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)