Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_O05
(919 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex sub... 332 1e-90
sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 co... 328 2e-89
sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 co... 324 2e-88
sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 co... 320 3e-87
sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex sub... 251 3e-66
sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC) 205 1e-52
sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex sub... 202 8e-52
sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC) 164 3e-40
sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropi... 32 2.5
sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropi... 32 2.5
>sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
sp|Q5R5Z5|ARPC2_PONPY Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 300
Score = 332 bits (850), Expect = 1e-90
Identities = 171/285 (60%), Positives = 215/285 (75%), Gaps = 2/285 (0%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSIT 208
MILLE N+ ++E L KF A +G K E ++ ADFDG +Y I+N DK + VSI+
Sbjct: 1 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSIS 60
Query: 209 LKFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 388
LKF+KELQ +GAD++LKR YG L N PE G NV++ YDL LP + + + H A +LKRN
Sbjct: 61 LKFYKELQAHGADELLKRVYGSFLVN-PESGYNVSLLYDLENLPASKDSIVHQAGMLKRN 119
Query: 389 CFASVFEMFFDYQESGNTNK-QAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGK 565
CFASVFE +F +QE G + +A+I+YRDDETMYV++ +DRVTVVFSTVFKD DDV+IGK
Sbjct: 120 CFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGK 179
Query: 566 VFIQELTEARRRVDRAPQVLYSPKEPPIELKGTKAATGDNVAYITFVLFNRHFATPAARK 745
VF+QE E RR APQVL+S +EPP+ELK T AA GDN+ YITFVLF RH +AR
Sbjct: 180 VFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRH-TNASARD 238
Query: 746 NSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRAKPE 880
N+I+LIHTFR+YLHYHIKCSKAYIH RMRAK+ +FLK+L RA+P+
Sbjct: 239 NTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARPD 283
>sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 301
Score = 328 bits (840), Expect = 2e-89
Identities = 167/285 (58%), Positives = 215/285 (75%), Gaps = 2/285 (0%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSIT 208
MILLE N+ ++E LL K+ A++G K E + +ADFDG +Y I+N DK + +SI+
Sbjct: 1 MILLEINNRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISIS 60
Query: 209 LKFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 388
LKF+K+LQE+GAD++LKREYG L D E G NV++ +L ++P++ E++A LLKRN
Sbjct: 61 LKFYKQLQEHGADELLKREYGS-LLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRN 119
Query: 389 CFASVFEMFFDYQESGNTN-KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGK 565
CFASVFE +FDYQE G K+A+INYR+DET+YV+A DRVTVVFST+F+D DDVIIGK
Sbjct: 120 CFASVFEKYFDYQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGK 179
Query: 566 VFIQELTEARRRVDRAPQVLYSPKEPPIELKGTKAATGDNVAYITFVLFNRHFATPAARK 745
VF+QEL E RR APQVL+S +EPP+EL T A GDN+ Y+TFVLF RH R
Sbjct: 180 VFMQELREGRRASHTAPQVLFSHREPPLELANTDARVGDNIGYVTFVLFPRH-TNKETRD 238
Query: 746 NSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRAKPE 880
N+I+LIH FR+YLHYHIKCSKAYIH RMRAK+ +FLK+L RA+PE
Sbjct: 239 NTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTSDFLKVLNRARPE 283
>sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 301
Score = 324 bits (831), Expect = 2e-88
Identities = 165/288 (57%), Positives = 214/288 (74%), Gaps = 3/288 (1%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSIT 208
MI+LE N+ + E+L QKF AK G K E + ADFDG +YK++N + D+ I +SI+
Sbjct: 1 MIILEQNNRIIVELLEQKFANAKEGGKPESVNVTFADFDGVLYKLSNPDGDRTKIILSIS 60
Query: 209 LKFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 388
LKF+ ELQ++GAD +L+R YG + + PE G NVT++Y+L LP + +L A+ LKRN
Sbjct: 61 LKFYTELQQHGADDLLRRVYGGHMRSTPEQGFNVTLEYNLADLPADTTDLVQAASALKRN 120
Query: 389 CFASVFEMFFDYQESGNT-NKQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGK 565
CFASVFE +F++QE+G +K+A+INYRDDETMY++A DRVTV+FSTVFKDADDVIIGK
Sbjct: 121 CFASVFEKYFEFQEAGQEGHKRAVINYRDDETMYIEAKADRVTVIFSTVFKDADDVIIGK 180
Query: 566 VFIQELTEARRRVDRAPQVLYSPKEPPIELKG-TKAATGDNVAYITFVLFNRHFATPAAR 742
VF+QE E R+ AP VLYS EPP+ELK +A GDNV YITFVLF RH +
Sbjct: 181 VFLQEFREGRKASQTAPAVLYSLGEPPLELKDLPEARVGDNVGYITFVLFPRH-TNKKTK 239
Query: 743 KNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRAKPEYR 886
N+IDLIH+FR+YLHYHIKCSK Y+H RMRAK+ +FLK+L RA+PE +
Sbjct: 240 DNTIDLIHSFRDYLHYHIKCSKVYLHTRMRAKTTDFLKVLNRARPEVK 287
>sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 304
Score = 320 bits (821), Expect = 3e-87
Identities = 167/288 (57%), Positives = 209/288 (72%), Gaps = 5/288 (1%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSIT 208
MILLE N+ V+E L KF A +G K E + +ADFDG ++ I+N DK + SI+
Sbjct: 1 MILLEINNRIVEETLTVKFKNAIAGNKAESIDVTVADFDGVLFHISNINGDKTKVRTSIS 60
Query: 209 LKFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 388
LKF+K+LQE+GAD++LKREYGD L PE G NV++ DL +P+N EE LLKRN
Sbjct: 61 LKFYKQLQEHGADELLKREYGDLLVA-PEDGYNVSVLVDLENIPENWEETVRKIGLLKRN 119
Query: 389 CFASVFEMFFDYQESGNTN----KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVI 556
CFASVFE +FD+Q G K+A+INYR+DETMYV+A DRVTVVFST+F+D DDV+
Sbjct: 120 CFASVFEKYFDFQSQGEGEGEGQKRAVINYRNDETMYVEAKPDRVTVVFSTIFRDEDDVV 179
Query: 557 IGKVFIQELTEARRRVDRAPQVLYSPKEPPIELKGTKAATGDNVAYITFVLFNRHFATPA 736
+GKVF+QEL E RR APQVL+S +EPP+EL T A G+N+ Y+TFVLF RH A
Sbjct: 180 LGKVFMQELREGRRASHTAPQVLFSHREPPLELANTGARVGENIGYVTFVLFPRHTA-KE 238
Query: 737 ARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRAKPE 880
R N+I+LIH FR+YLHYHIKCSKAYIH RMRAK+ FLK+L RA+PE
Sbjct: 239 TRDNTINLIHMFRDYLHYHIKCSKAYIHSRMRAKTTEFLKVLNRARPE 286
>sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 191
Score = 251 bits (640), Expect = 3e-66
Identities = 122/191 (63%), Positives = 151/191 (79%), Gaps = 1/191 (0%)
Frame = +2
Query: 311 TIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFFDYQESGNTNK-QAIINYRDDETMY 487
++ YDL LP + + + H A +LKRNCFASVFE +F +QE G + +A+I+YRDDETMY
Sbjct: 1 SLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMY 60
Query: 488 VKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRRVDRAPQVLYSPKEPPIELKGTK 667
V++ +DRVTVVFSTVFKD DDV+IGKVF+QE E RR APQVL+S +EPP+ELK T
Sbjct: 61 VESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTD 120
Query: 668 AATGDNVAYITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSEN 847
AA GDN+ YITFVLF RH AR N+I+LIHTFR+YLHYHIKCSKAYIH RMRAK+ +
Sbjct: 121 AAVGDNIGYITFVLFPRH-TNATARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSD 179
Query: 848 FLKLLKRAKPE 880
FLK+L RA+P+
Sbjct: 180 FLKVLNRARPD 190
>sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC)
Length = 317
Score = 205 bits (522), Expect = 1e-52
Identities = 124/307 (40%), Positives = 184/307 (59%), Gaps = 24/307 (7%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEKDKNIIYVSITL 211
M+ L+Y N + E+L ++F S + Q + DFDG + I+ ++K I +S+++
Sbjct: 1 MLSLDYNNIFIYELLTERF----SSENPSSIDQVVTDFDGVTFHISTPEEKTKILISLSM 56
Query: 212 KFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLP---DNIEELAHNAALLK 382
K + EL YG +LK+ YG + ++PE G N +I DL +LP + E+LA + ++LK
Sbjct: 57 KCYPELVNYGTLDLLKQIYGAYV-HEPEMGYNFSILIDLQQLPATDEEKEQLAMSISMLK 115
Query: 383 RNCFASVFEMFF------------DYQESGNTNKQAI------INYRDDETMYVKAMEDR 508
RN A+ F F D + + +KQA I+YRD+ET+ + DR
Sbjct: 116 RNVLAAPFHRAFTKQAELADLARKDPENAPMLDKQATSQELMAIHYRDEETIVLWPEHDR 175
Query: 509 VTVVFSTVFKDADDVIIGKVFIQELTEARRR--VDRAPQVLYSPKEPPIELKGTKAAT-G 679
VTVVFST F++ D I GKVF+QE +ARRR + APQVL+S ++PP+E++ + G
Sbjct: 176 VTVVFSTKFREETDRIFGKVFLQEFVDARRRPAIQTAPQVLFSYRDPPLEIRDIQGIQKG 235
Query: 680 DNVAYITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKL 859
D+ ++TFVLF RHF TP R++ I I FRN LH+HIK SKAY+H RMR + +F K+
Sbjct: 236 DDFGFVTFVLFERHF-TPQNREDCISHIQVFRNTLHFHIKASKAYMHQRMRKRVADFQKV 294
Query: 860 LKRAKPE 880
L RAKP+
Sbjct: 295 LNRAKPD 301
>sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 293
Score = 202 bits (515), Expect = 8e-52
Identities = 114/286 (39%), Positives = 165/286 (57%), Gaps = 3/286 (1%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEKDKNIIYVSITL 211
M+LLE N+ + + ++ F + ++ ADFDG + + DK+ + VS++L
Sbjct: 1 MLLLETHNRILYDEVISHFEGDR------RVNNIFADFDGVKFNVQTSDDKSSLMVSVSL 54
Query: 212 KFFKELQEYGADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNC 391
+L + G +LK YGD L PE G +VT+ + N EELA +LLKR+
Sbjct: 55 HAAADLLKNGGSALLKSVYGDMLQAKPEGGYDVTLVIQ-SSFSGNKEELAKKVSLLKRHL 113
Query: 392 FASVFEMFFDYQESGNTNKQAI-INYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKV 568
A+ F M F+ E+ + I INYR DET Y+K D V V+F FKDADDVI+ K+
Sbjct: 114 VAAPFLMVFEGIEAKKPLPEIIAINYRTDETFYLKPQGDNVIVIFDIAFKDADDVILSKI 173
Query: 569 FIQELTEARRRVDRAPQVLYSPKEPPIELKGTKA--ATGDNVAYITFVLFNRHFATPAAR 742
F+Q + R+ + P + +S K+PP+ELKG K A N +++FVLF H P
Sbjct: 174 FLQSFVDVRKTISNVPSITFSQKDPPLELKGVKGVRAGQANHGFVSFVLFPAHIKKP--- 230
Query: 743 KNSIDLIHTFRNYLHYHIKCSKAYIHMRMRAKSENFLKLLKRAKPE 880
+ S DLI TFR+YLHYHIKC+K Y+H MR + E+ +++L RAKPE
Sbjct: 231 QESADLIQTFRDYLHYHIKCAKGYMHTSMRNRVESLIQVLNRAKPE 276
>sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC)
Length = 342
Score = 164 bits (415), Expect = 3e-40
Identities = 112/318 (35%), Positives = 171/318 (53%), Gaps = 37/318 (11%)
Frame = +2
Query: 32 MILLEYFNKGVKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNE-KDKNIIYVSIT 208
M+ L+ N +++ L + A + G+ + M + ++DFD Y I+N +DK+I+ +S+
Sbjct: 1 MLHLQPQNLLIQKTLNEAIEALRKGSPLT-MDRIVSDFDYTTYHISNTAEDKSILLLSVK 59
Query: 209 LKFFKELQEYGAD------KVLKREY----GDRLCNDPEPGSNVTIQYDLTKLPDNIEEL 358
K + + E D K L Y G + ++ EPG + T+Q L +L ++E
Sbjct: 60 TKAWVSVSECQLDGSLTLLKFLADHYSSLGGVTIPSEVEPGYDYTLQITLAEL---VQES 116
Query: 359 AHNAALLKRNCFASVFEM----FFDYQE----------------SGNTNKQAIINYRDDE 478
++LK + FE+ F + + + N I YRD+E
Sbjct: 117 ILQLSVLKTIILSFPFELAISKFIELSQQQPAPVEAEITGGEVAANGDNTLFTIKYRDEE 176
Query: 479 TMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRR---VDRAPQVLYSPKEPPI 649
+++K DRVT++F T+F+D D I GKVF+QE +AR+R + APQVLYS EPP+
Sbjct: 177 NIFIKPSNDRVTIIFETIFQDETDKIFGKVFLQEFVDARKRNRQIQSAPQVLYS-HEPPL 235
Query: 650 ELKGT---KAATGDNVAYITFVLFNRHFATPAARKNSIDLIHTFRNYLHYHIKCSKAYIH 820
ELK + +ITFVLF RHF T + +SI + FRNY HYHIKCSKAY+H
Sbjct: 236 ELKRLYQPPKVAEQSRRFITFVLFPRHFQTKELQFHSICQLTLFRNYFHYHIKCSKAYMH 295
Query: 821 MRMRAKSENFLKLLKRAK 874
RMR + ++F+K+L RAK
Sbjct: 296 SRMRFRVDSFIKVLNRAK 313
>sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropic repressor codY
Length = 257
Score = 32.0 bits (71), Expect = 2.5
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%)
Frame = +2
Query: 113 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 262
++K K DF I+N N+ VS K + +++ D+ + R
Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73
Query: 263 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 370
EY + L N + SN+ I +LT P E+ N+
Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
>sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropic repressor codY
Length = 256
Score = 32.0 bits (71), Expect = 2.5
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%)
Frame = +2
Query: 113 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 262
++K K DF I+N N+ VS K + +++ D+ + R
Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73
Query: 263 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 370
EY + L N + SN+ I +LT P E+ N+
Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,540,612
Number of Sequences: 369166
Number of extensions: 1688662
Number of successful extensions: 5251
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5041
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5222
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9366655350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)