Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_C21
(751 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex sub... 232 9e-61
sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 co... 232 9e-61
sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 co... 229 5e-60
sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 co... 224 1e-58
sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex sub... 160 4e-39
sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex sub... 135 9e-32
sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC) 129 6e-30
sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC) 98 2e-20
sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropi... 32 1.8
sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropi... 32 1.8
>sp|O15144|ARPC2_HUMAN Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
sp|Q5R5Z5|ARPC2_PONPY Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 300
Score = 232 bits (591), Expect = 9e-61
Identities = 120/211 (56%), Positives = 154/211 (72%), Gaps = 2/211 (0%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSITLKFFKELQEY 229
++E L KF A +G K E ++ ADFDG +Y I+N DK + VSI+LKF+KELQ +
Sbjct: 11 IEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAH 70
Query: 230 GADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFF 409
GAD++LKR YG L N PE G NV++ YDL LP + + + H A +LKRNCFASVFE +F
Sbjct: 71 GADELLKRVYGSFLVN-PESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYF 129
Query: 410 DYQESGNTNK-QAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEAR 586
+QE G + +A+I+YRDDETMYV++ +DRVTVVFSTVFKD DDV+IGKVF+QE E R
Sbjct: 130 QFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGR 189
Query: 587 RRVDRAPQVLYSPKEPPIELKGTKAATGDNV 679
R APQVL+S +EPP+ELK T AA GDN+
Sbjct: 190 RASHTAPQVLFSHREPPLELKDTDAAVGDNI 220
>sp|Q9VIM5|ARPC2_DROME Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 301
Score = 232 bits (591), Expect = 9e-61
Identities = 118/211 (55%), Positives = 157/211 (74%), Gaps = 2/211 (0%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEK-DKNIIYVSITLKFFKELQEY 229
++E LL K+ A++G K E + +ADFDG +Y I+N DK + +SI+LKF+K+LQE+
Sbjct: 11 IEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYKQLQEH 70
Query: 230 GADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFF 409
GAD++LKREYG L D E G NV++ +L ++P++ E++A LLKRNCFASVFE +F
Sbjct: 71 GADELLKREYGS-LLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRNCFASVFEKYF 129
Query: 410 DYQESGNTN-KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEAR 586
DYQE G K+A+INYR+DET+YV+A DRVTVVFST+F+D DDVIIGKVF+QEL E R
Sbjct: 130 DYQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELREGR 189
Query: 587 RRVDRAPQVLYSPKEPPIELKGTKAATGDNV 679
R APQVL+S +EPP+EL T A GDN+
Sbjct: 190 RASHTAPQVLFSHREPPLELANTDARVGDNI 220
>sp|Q8WTM6|ARPC2_CAEEL Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 301
Score = 229 bits (585), Expect = 5e-60
Identities = 118/212 (55%), Positives = 155/212 (73%), Gaps = 3/212 (1%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSITLKFFKELQEY 229
+ E+L QKF AK G K E + ADFDG +YK++N + D+ I +SI+LKF+ ELQ++
Sbjct: 11 IVELLEQKFANAKEGGKPESVNVTFADFDGVLYKLSNPDGDRTKIILSISLKFYTELQQH 70
Query: 230 GADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFF 409
GAD +L+R YG + + PE G NVT++Y+L LP + +L A+ LKRNCFASVFE +F
Sbjct: 71 GADDLLRRVYGGHMRSTPEQGFNVTLEYNLADLPADTTDLVQAASALKRNCFASVFEKYF 130
Query: 410 DYQESGNT-NKQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEAR 586
++QE+G +K+A+INYRDDETMY++A DRVTV+FSTVFKDADDVIIGKVF+QE E R
Sbjct: 131 EFQEAGQEGHKRAVINYRDDETMYIEAKADRVTVIFSTVFKDADDVIIGKVFLQEFREGR 190
Query: 587 RRVDRAPQVLYSPKEPPIELKG-TKAATGDNV 679
+ AP VLYS EPP+ELK +A GDNV
Sbjct: 191 KASQTAPAVLYSLGEPPLELKDLPEARVGDNV 222
>sp|Q7PVX8|ARPC2_ANOGA Probable actin-related protein 2/3 complex subunit 2 (ARP2/3
complex 34 kDa subunit) (p34-ARC)
Length = 304
Score = 224 bits (572), Expect = 1e-58
Identities = 117/214 (54%), Positives = 151/214 (70%), Gaps = 5/214 (2%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITN-EKDKNIIYVSITLKFFKELQEY 229
V+E L KF A +G K E + +ADFDG ++ I+N DK + SI+LKF+K+LQE+
Sbjct: 11 VEETLTVKFKNAIAGNKAESIDVTVADFDGVLFHISNINGDKTKVRTSISLKFYKQLQEH 70
Query: 230 GADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFF 409
GAD++LKREYGD L PE G NV++ DL +P+N EE LLKRNCFASVFE +F
Sbjct: 71 GADELLKREYGDLLVA-PEDGYNVSVLVDLENIPENWEETVRKIGLLKRNCFASVFEKYF 129
Query: 410 DYQESGNTN----KQAIINYRDDETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELT 577
D+Q G K+A+INYR+DETMYV+A DRVTVVFST+F+D DDV++GKVF+QEL
Sbjct: 130 DFQSQGEGEGEGQKRAVINYRNDETMYVEAKPDRVTVVFSTIFRDEDDVVLGKVFMQELR 189
Query: 578 EARRRVDRAPQVLYSPKEPPIELKGTKAATGDNV 679
E RR APQVL+S +EPP+EL T A G+N+
Sbjct: 190 EGRRASHTAPQVLFSHREPPLELANTGARVGENI 223
>sp|Q9CVB6|ARPC2_MOUSE Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 191
Score = 160 bits (404), Expect = 4e-39
Identities = 77/127 (60%), Positives = 98/127 (77%), Gaps = 1/127 (0%)
Frame = +2
Query: 302 TIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFFDYQESGNTNK-QAIINYRDDETMY 478
++ YDL LP + + + H A +LKRNCFASVFE +F +QE G + +A+I+YRDDETMY
Sbjct: 1 SLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMY 60
Query: 479 VKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRRVDRAPQVLYSPKEPPIELKGTK 658
V++ +DRVTVVFSTVFKD DDV+IGKVF+QE E RR APQVL+S +EPP+ELK T
Sbjct: 61 VESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTD 120
Query: 659 AATGDNV 679
AA GDN+
Sbjct: 121 AAVGDNI 127
>sp|O96623|ARPC2_DICDI Actin-related protein 2/3 complex subunit 2 (ARP2/3 complex 34 kDa
subunit) (p34-ARC)
Length = 293
Score = 135 bits (341), Expect = 9e-32
Identities = 73/184 (39%), Positives = 105/184 (57%), Gaps = 1/184 (0%)
Frame = +2
Query: 110 KMKQCLADFDGAIYKITNEKDKNIIYVSITLKFFKELQEYGADKVLKREYGDRLCNDPEP 289
++ ADFDG + + DK+ + VS++L +L + G +LK YGD L PE
Sbjct: 24 RVNNIFADFDGVKFNVQTSDDKSSLMVSVSLHAAADLLKNGGSALLKSVYGDMLQAKPEG 83
Query: 290 GSNVTIQYDLTKLPDNIEELAHNAALLKRNCFASVFEMFFDYQESGNTNKQAI-INYRDD 466
G +VT+ + N EELA +LLKR+ A+ F M F+ E+ + I INYR D
Sbjct: 84 GYDVTLVIQ-SSFSGNKEELAKKVSLLKRHLVAAPFLMVFEGIEAKKPLPEIIAINYRTD 142
Query: 467 ETMYVKAMEDRVTVVFSTVFKDADDVIIGKVFIQELTEARRRVDRAPQVLYSPKEPPIEL 646
ET Y+K D V V+F FKDADDVI+ K+F+Q + R+ + P + +S K+PP+EL
Sbjct: 143 ETFYLKPQGDNVIVIFDIAFKDADDVILSKIFLQSFVDVRKTISNVPSITFSQKDPPLEL 202
Query: 647 KGTK 658
KG K
Sbjct: 203 KGVK 206
>sp|O14241|ARPC2_SCHPO ARP2/3 complex 34 kDa subunit (p34-ARC)
Length = 317
Score = 129 bits (325), Expect = 6e-30
Identities = 82/222 (36%), Positives = 128/222 (57%), Gaps = 23/222 (10%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFFKELQEYG 232
+ E+L ++F S + Q + DFDG + I+ ++K I +S+++K + EL YG
Sbjct: 11 IYELLTERF----SSENPSSIDQVVTDFDGVTFHISTPEEKTKILISLSMKCYPELVNYG 66
Query: 233 ADKVLKREYGDRLCNDPEPGSNVTIQYDLTKLP---DNIEELAHNAALLKRNCFASVFEM 403
+LK+ YG + ++PE G N +I DL +LP + E+LA + ++LKRN A+ F
Sbjct: 67 TLDLLKQIYGAYV-HEPEMGYNFSILIDLQQLPATDEEKEQLAMSISMLKRNVLAAPFHR 125
Query: 404 FF------------DYQESGNTNKQAI------INYRDDETMYVKAMEDRVTVVFSTVFK 529
F D + + +KQA I+YRD+ET+ + DRVTVVFST F+
Sbjct: 126 AFTKQAELADLARKDPENAPMLDKQATSQELMAIHYRDEETIVLWPEHDRVTVVFSTKFR 185
Query: 530 DADDVIIGKVFIQELTEARRR--VDRAPQVLYSPKEPPIELK 649
+ D I GKVF+QE +ARRR + APQVL+S ++PP+E++
Sbjct: 186 EETDRIFGKVFLQEFVDARRRPAIQTAPQVLFSYRDPPLEIR 227
>sp|P53731|ARPC2_YEAST ARP2/3 complex 34 kDa subunit (p34-ARC)
Length = 342
Score = 98.2 bits (243), Expect = 2e-20
Identities = 73/233 (31%), Positives = 119/233 (51%), Gaps = 34/233 (14%)
Frame = +2
Query: 53 VKEILLQKFMAAKSGAKVEKMKQCLADFDGAIYKITNE-KDKNIIYVSITLKFFKELQEY 229
+++ L + A + G+ + M + ++DFD Y I+N +DK+I+ +S+ K + + E
Sbjct: 11 IQKTLNEAIEALRKGSPLT-MDRIVSDFDYTTYHISNTAEDKSILLLSVKTKAWVSVSEC 69
Query: 230 GAD------KVLKREY----GDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNAALLKRN 379
D K L Y G + ++ EPG + T+Q L +L ++E ++LK
Sbjct: 70 QLDGSLTLLKFLADHYSSLGGVTIPSEVEPGYDYTLQITLAEL---VQESILQLSVLKTI 126
Query: 380 CFASVFEM----FFDYQE----------------SGNTNKQAIINYRDDETMYVKAMEDR 499
+ FE+ F + + + N I YRD+E +++K DR
Sbjct: 127 ILSFPFELAISKFIELSQQQPAPVEAEITGGEVAANGDNTLFTIKYRDEENIFIKPSNDR 186
Query: 500 VTVVFSTVFKDADDVIIGKVFIQELTEARRR---VDRAPQVLYSPKEPPIELK 649
VT++F T+F+D D I GKVF+QE +AR+R + APQVLYS EPP+ELK
Sbjct: 187 VTIIFETIFQDETDKIFGKVFLQEFVDARKRNRQIQSAPQVLYS-HEPPLELK 238
>sp|Q8CPG9|CODY_STAES GTP-sensing transcriptional pleiotropic repressor codY
Length = 257
Score = 32.0 bits (71), Expect = 1.8
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%)
Frame = +2
Query: 104 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 253
++K K DF I+N N+ VS K + +++ D+ + R
Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73
Query: 254 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 361
EY + L N + SN+ I +LT P E+ N+
Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
>sp|Q5HPT7|CODY_STAEQ GTP-sensing transcriptional pleiotropic repressor codY
Length = 256
Score = 32.0 bits (71), Expect = 1.8
Identities = 24/96 (25%), Positives = 40/96 (41%), Gaps = 10/96 (10%)
Frame = +2
Query: 104 VEKMKQCLADFDGAIYKITNEKDKNIIYVSITLKFF----------KELQEYGADKVLKR 253
++K K DF I+N N+ VS K + +++ D+ + R
Sbjct: 14 LQKHKGIAVDFKDVAQTISNVTVTNVFIVSRRGKILGSCLNELLKSERIKDMLEDRHIPR 73
Query: 254 EYGDRLCNDPEPGSNVTIQYDLTKLPDNIEELAHNA 361
EY + L N + SN+ I +LT P E+ N+
Sbjct: 74 EYTEELMNVKQTESNIDIDNELTVFPPENREVFLNS 109
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,454,360
Number of Sequences: 369166
Number of extensions: 1381661
Number of successful extensions: 4402
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4256
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4383
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6824907600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)