DrC_00527
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00527 (789 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase... 202 1e-51 sp|P60051|UBP14_PANTR Ubiquitin carboxyl-terminal hydrolase... 202 1e-51 sp|P40826|UBP14_RABIT Ubiquitin carboxyl-terminal hydrolase... 201 2e-51 sp|Q9JMA1|UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase... 199 6e-51 sp|Q17361|UBP14_CAEEL Ubiquitin carboxyl-terminal hydrolase... 120 4e-27 sp|Q92353|UBP6_SCHPO Probable ubiquitin carboxyl-terminal h... 106 8e-23 sp|P43593|UBP6_YEAST Ubiquitin carboxyl-terminal hydrolase ... 86 1e-16 sp|Q9BXU7|UBP26_HUMAN Ubiquitin carboxyl-terminal hydrolase... 44 4e-04 sp|Q9P275|UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase... 43 9e-04 sp|Q09931|UBPY_CAEEL Probable ubiquitin carboxyl-terminal h... 42 0.002
>sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 494 Score = 202 bits (513), Expect = 1e-51 Identities = 111/268 (41%), Positives = 160/268 (59%), Gaps = 9/268 (3%) Frame = +3 Query: 12 MPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNT-WDG 188 MP+Y V +KW KEKF +E +TD+PP +FKA +F+L+GV P RQKVM+ GGTLK+ W Sbjct: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 Query: 189 IRLKDGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATI 368 I++K+G+T++MMG+ D L K F+EDMTE Q+ A++LP GL N+GNTCY+NAT+ Sbjct: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 Query: 369 QCLRTIPELYKAIKNSP----KTNESDPHSRFVLSLGRLILSMETAEVPIAPIIPLKHLH 536 QC+R++PEL A+K + E +L L SM+ I PII L+ LH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 537 EMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQKAVYIPQNVDFSDLPESFGS- 713 PQFA E+G +QQDANECW +++R LQ+ + ++ + S S Sbjct: 181 MAFPQFA-------EKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASA 233 Query: 714 ---NGNLNFVDQFLTGKFDVKTVNTENE 788 + + +DQF +F+ TE+E Sbjct: 234 ATPSKKKSLIDQFFGVEFETTMKCTESE 261
>sp|P60051|UBP14_PANTR Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 202 bits (513), Expect = 1e-51 Identities = 111/268 (41%), Positives = 160/268 (59%), Gaps = 9/268 (3%) Frame = +3 Query: 12 MPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNT-WDG 188 MP+Y V +KW KEKF +E +TD+PP +FKA +F+L+GV P RQKVM+ GGTLK+ W Sbjct: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 Query: 189 IRLKDGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATI 368 I++K+G+T++MMG+ D L K F+EDMTE Q+ A++LP GL N+GNTCY+NAT+ Sbjct: 61 IKIKNGMTLLMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 Query: 369 QCLRTIPELYKAIKNSP----KTNESDPHSRFVLSLGRLILSMETAEVPIAPIIPLKHLH 536 QC+R++PEL A+K + E +L L SM+ I PII L+ LH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 537 EMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQKAVYIPQNVDFSDLPESFGS- 713 PQFA E+G +QQDANECW +++R LQ+ + ++ + S S Sbjct: 181 MAFPQFA-------EKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSSASA 233 Query: 714 ---NGNLNFVDQFLTGKFDVKTVNTENE 788 + + +DQF +F+ TE+E Sbjct: 234 ATPSKKKSLIDQFFGVEFETTMKCTESE 261
>sp|P40826|UBP14_RABIT Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 201 bits (510), Expect = 2e-51 Identities = 110/267 (41%), Positives = 160/267 (59%), Gaps = 8/267 (2%) Frame = +3 Query: 12 MPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNT-WDG 188 MP+Y V +KW KEKF +E +TD+PP +FKA +F+L+GV P RQ+VM+ GGTLK+ W Sbjct: 1 MPLYSVTVKWGKEKFGGVELNTDEPPMVFKAQLFALTGVQPARQRVMVKGGTLKDDDWGN 60 Query: 189 IRLKDGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATI 368 I++K+G+TI+MMG+ D L K F+EDMTE Q+ A++LP GL N+GNTCY+NAT+ Sbjct: 61 IKIKNGMTILMMGSADALPEEPSAKTVFVEDMTEEQLASAMELPCGLTNLGNTCYMNATV 120 Query: 369 QCLRTIPELYKAIKNSP----KTNESDPHSRFVLSLGRLILSMETAEVPIAPIIPLKHLH 536 QC+R++PEL A+K + E +L L SM+ I PII L+ LH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 537 EMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQKAVYIPQNVDFSDLPESFGS- 713 PQFA E+G +QQDANECW +++R LQ+ + ++ + S + Sbjct: 181 MAFPQFA-------EKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETDSSAAAV 233 Query: 714 --NGNLNFVDQFLTGKFDVKTVNTENE 788 + + +DQF +F+ TE+E Sbjct: 234 APSKKKSLIDQFFGVEFETTMKCTESE 260
>sp|Q9JMA1|UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 199 bits (507), Expect = 6e-51 Identities = 112/269 (41%), Positives = 160/269 (59%), Gaps = 10/269 (3%) Frame = +3 Query: 12 MPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNT-WDG 188 MP+Y V +KW KEKF +E +TD+PP +FKA +F+L+GV P RQKVM+ GGTLK+ W Sbjct: 1 MPLYSVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDDDWGN 60 Query: 189 IRLKDGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATI 368 I++K+G+T++MMG+ D L K F+EDMTE Q+ A++LP GL N+GNTCY+NAT+ Sbjct: 61 IKMKNGMTVLMMGSADALPEEPSAKTVFVEDMTEEQLATAMELPCGLTNLGNTCYMNATV 120 Query: 369 QCLRTIPELYKAIKNSP----KTNESDPHSRFVLSLGRLILSMETAEVPIAPIIPLKHLH 536 QC+R++PEL A+K + E +L L SM+ I PII L+ LH Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSMDKTSSSIPPIILLQFLH 180 Query: 537 EMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQKAVYIPQN-----VDFSDLPE 701 PQFA E+G +QQDANECW +++R LQ+ + ++ D S P Sbjct: 181 MAFPQFA-------EKGEQGQYLQQDANECWIQMMRVLQQKLEAIEDDSGRETDSSSAPA 233 Query: 702 SFGSNGNLNFVDQFLTGKFDVKTVNTENE 788 S + +DQ+ +F+ TE+E Sbjct: 234 VTPSK-KKSLIDQYFGVEFETTMKCTESE 261
>sp|Q17361|UBP14_CAEEL Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 489 Score = 120 bits (301), Expect = 4e-27 Identities = 80/228 (35%), Positives = 121/228 (53%), Gaps = 13/228 (5%) Frame = +3 Query: 12 MPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTL-KNTWDG 188 MP+ VN+KWQKEK+ +E DT PP +FKA +F+L+ V P+RQKV++ G TL + W+G Sbjct: 1 MPI--VNVKWQKEKYV-VEVDTSAPPMVFKAQLFALTQVVPERQKVVIMGRTLGDDDWEG 57 Query: 189 IRLKDGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALK-----LPQGLKNIGNTCY 353 I +K+ +TIMMMG S+GEI KP + + ++ K + P GL N+GNTCY Sbjct: 58 ITIKENMTIMMMG-----SVGEIPKPPTVLEKKQANRDKQAEEISALYPCGLANLGNTCY 112 Query: 354 LNATIQCLRTIPELYKAIKNSPKTNESDPHSRFVLSLGRLILSMETAE-------VPIAP 512 N+ +Q L+ + EL +K + + + + R +L L S+ + PI P Sbjct: 113 FNSCVQMLKEVNEL--VLKPAEEMRIREHNDRLCHNLATLFNSLRDKDRALRSKGEPIKP 170 Query: 513 IIPLKHLHEMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQK 656 + L + PQF QQDANEC I+ ++ + Sbjct: 171 FAAILTLSDSFPQF-------------EKFKQQDANECLVSIMSNVTR 205
>sp|Q92353|UBP6_SCHPO Probable ubiquitin carboxyl-terminal hydrolase 6 (Ubiquitin thiolesterase 6) (Ubiquitin-specific processing protease 6) (Deubiquitinating enzyme 6) Length = 467 Score = 106 bits (264), Expect = 8e-23 Identities = 74/219 (33%), Positives = 116/219 (52%), Gaps = 7/219 (3%) Frame = +3 Query: 27 VNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNT--WDGIRLK 200 + I+WQ +K+ D+E + ++ K ++SL+ V P+RQKV++ GG LK+ + +K Sbjct: 4 IAIRWQGKKY-DLEIEPNETGSTLKHQLYSLTQVPPERQKVIVKGGQLKDDVLLGSVGIK 62 Query: 201 DGITIMMMGTCDDLSLGEINKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATIQCLR 380 T++MMGT +L P + E + ++ P GL N+GNTCY+N+T+Q LR Sbjct: 63 PNATLLMMGTAGELPTA---MPIPAVESVEQEESEDDGYPSGLINLGNTCYMNSTVQMLR 119 Query: 381 TIPELYKAIKNSPKTNESDPHSRFVLSLG-----RLILSMETAEVPIAPIIPLKHLHEMC 545 IPEL SD S+F S G R +L+ + P+ P+ L+ L Sbjct: 120 AIPEL------------SDAVSQFNSSGGLVAEYRTLLNSMQSNAPVTPMRFLQSLRMEY 167 Query: 546 PQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQKAV 662 PQFA + E GG QQDA ECW+ ++ LQ+++ Sbjct: 168 PQFAE---MSRETGG---YAQQDAEECWSFLLSVLQRSL 200
>sp|P43593|UBP6_YEAST Ubiquitin carboxyl-terminal hydrolase 6 (Ubiquitin thiolesterase 6) (Ubiquitin-specific processing protease 6) (Deubiquitinating enzyme 6) Length = 499 Score = 85.9 bits (211), Expect = 1e-16 Identities = 73/229 (31%), Positives = 108/229 (47%), Gaps = 13/229 (5%) Frame = +3 Query: 3 SGEMPVYKVNIKWQKEKFNDIECDTDQPPEIFKALIFSLSGVTPDRQKVMMPGGTLKNTW 182 SGE ++ NI+ K I TD K+ L+ V RQK M+ GG Sbjct: 2 SGE--TFEFNIR-HSGKVYPITLSTDATSADLKSKAEELTQVPSARQKYMVKGGLSGEES 58 Query: 183 DGIR--LKDGITIMMMGTCD-DLSLGEINKPKFIEDMT-ESQITKALKLPQGLKNIGNTC 350 I +K G T+M++GT D +L K FIED+ E Q+ + +LP G KN+GNTC Sbjct: 59 IKIYPLIKPGSTVMLLGTPDANLISKPAKKNNFIEDLAPEQQVQQFAQLPVGFKNMGNTC 118 Query: 351 YLNATIQCLRTIPELYKAIKN--------SPKTNESDPHSRFVLSLGRLILSMETAEV-P 503 YLNAT+Q L + +L I N + + + H + V+ + R +++ Sbjct: 119 YLNATLQALYRVNDLRDMILNYNPSQGVSNSGAQDEEIHKQIVIEMKRCFENLQNKSFKS 178 Query: 504 IAPIIPLKHLHEMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSL 650 + PI+ L L + PQFA QGG QQDA E + ++ S+ Sbjct: 179 VLPIVLLNTLRKCYPQFAERD----SQGG--FYKQQDAEELFTQLFHSM 221
>sp|Q9BXU7|UBP26_HUMAN Ubiquitin carboxyl-terminal hydrolase 26 (Ubiquitin thiolesterase 26) (Ubiquitin-specific processing protease 26) (Deubiquitinating enzyme 26) Length = 913 Score = 44.3 bits (103), Expect = 4e-04 Identities = 23/71 (32%), Positives = 36/71 (50%) Frame = +3 Query: 312 KLPQGLKNIGNTCYLNATIQCLRTIPELYKAIKNSPKTNESDPHSRFVLSLGRLILSMET 491 K+ GL N+GNTCY+NA +Q L +IP + N P + + L RL+ +T Sbjct: 292 KICHGLPNLGNTCYMNAVLQSLLSIPSFADDLLNQSFPWGKIPLNALTMCLARLLFFKDT 351 Query: 492 AEVPIAPIIPL 524 + I ++ L Sbjct: 352 YNIEIKEMLLL 362
>sp|Q9P275|UBP36_HUMAN Ubiquitin carboxyl-terminal hydrolase 36 (Ubiquitin thiolesterase 36) (Ubiquitin-specific processing protease 36) (Deubiquitinating enzyme 36) Length = 1121 Score = 43.1 bits (100), Expect = 9e-04 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 2/121 (1%) Frame = +3 Query: 303 KALKLPQGLKNIGNTCYLNATIQCLRTIPEL--YKAIKNSPKTNESDPHSRFVLSLGRLI 476 + ++ GL N+GNTC+LNATIQCL P L Y K ++ + ++ Sbjct: 116 RVFRVGAGLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIV 175 Query: 477 LSMETAEVPIAPIIPLKHLHEMCPQFATTQVAAPEQGGGSVLMQQDANECWAEIVRSLQK 656 + + I P+ ++ L ++ F Q+DA+E + ++QK Sbjct: 176 QAFANSGNAIKPVSFIRDLKKIARHFRFGN-------------QEDAHEFLRYTIDAMQK 222 Query: 657 A 659 A Sbjct: 223 A 223
>sp|Q09931|UBPY_CAEEL Probable ubiquitin carboxyl-terminal hydrolase K02C4.3 (Ubiquitin thiolesterase) (Ubiquitin-specific processing protease) (Deubiquitinating enzyme) Length = 1302 Score = 42.0 bits (97), Expect = 0.002 Identities = 38/164 (23%), Positives = 70/164 (42%), Gaps = 15/164 (9%) Frame = +3 Query: 255 INKPKFIEDMTESQITKALKLPQGLKNIGNTCYLNATIQCLRTIPELYKAI--------K 410 I++P + E + GL N GNTC+LN Q L +IP+ + Sbjct: 178 ISRPTMLMSNLEDMVRNP-NFSTGLYNSGNTCWLNCLSQVLYSIPKFRSILYHCAPLSWH 236 Query: 411 NSPKTN---ESDPHSRFVLSLGRLILSMETAEVPIAPIIPLKHLHEMCPQFATTQVAAPE 581 P TN E+ H+ ++ L ++ +E+ + PL ++ +++ Sbjct: 237 EQPITNVKIENQQHAELLMLFRGLFAELQFSEMKYIEVGPLINM--------VDKLSKSS 288 Query: 582 QGGGSVLMQQDANECWAEIVRSLQK----AVYIPQNVDFSDLPE 701 +G ++ QQDA E I LQ+ A++ N +FS++ + Sbjct: 289 KGPSTIGTQQDATEMLTLIFDWLQRAFDAALHAQLNPEFSNVSD 332
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 91,173,969
Number of Sequences: 369166
Number of extensions: 1862405
Number of successful extensions: 4465
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4318
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4446
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
