Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00516 (971 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9QZ06|TOLIP_MOUSE Toll-interacting protein 175 2e-43 sp|Q9H0E2|TOLIP_HUMAN Toll-interacting protein 169 8e-42 sp|Q9C8S6|Y1322_ARATH C2 domain protein At1g63220 44 7e-04 sp|P93733|PLDB1_ARATH Phospholipase D beta 1 (AtPLDbeta1) (... 42 0.003 sp|O23078|PLDB2_ARATH Phospholipase D beta 2 (AtPLDbeta2) (... 42 0.003 sp|O14065|YC31_SCHPO Hypothetical protein C962.01 in chromo... 41 0.006 sp|Q8K0T7|UN13C_MOUSE Unc-13 homolog C (Munc13-3) 40 0.008 sp|Q62770|UN13C_RAT Unc-13 homolog C (Munc13-3) 39 0.017 sp|Q8NB66|UN13C_HUMAN Unc-13 homolog C (Munc13-3) 39 0.017 sp|Q9Z268|RASL1_MOUSE RasGAP-activating-like protein 1 39 0.022
>sp|Q9QZ06|TOLIP_MOUSE Toll-interacting protein Length = 274 Score = 175 bits (444), Expect = 2e-43 Identities = 100/275 (36%), Positives = 145/275 (52%), Gaps = 20/275 (7%) Frame = +2 Query: 62 SIEEKRKRCLLGELPDDFLRIPXXXXXXXXXXXXTSGMMYPQLQVMPAPXXXXXXXXXXX 241 ++ +R +GELP DFLRI + Q+ Sbjct: 4 TVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQ-----QLQYGGTVGTVGRLSIT 58 Query: 242 XXXARLAKNYGITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHIS 421 A+LAKNYG+TRMDPYC++R+G+ YET TA NG+KNP WNK C +P GV++ ++ Sbjct: 59 VVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLE 118 Query: 422 IYDEKTMSADEEIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVL---SIKEV 592 I+DE+ S D+ IA+ IT P + QG V D WY L+G+QG+++EG IN+V+ S+ Sbjct: 119 IFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAA 178 Query: 593 QMMQP-PTFPMPVRQMVTPGYV----MPT------------QPHVRPAPVITDADVDQIH 721 MM P P MP GYV MP P V P P + D+ I Sbjct: 179 MMMPPQPVVLMPTVYQQGVGYVPIAGMPAVCSPGMVPMAMPPPAVAPQPRCNEEDLKAIQ 238 Query: 722 EMFPTIEKKVIKDMLVENGGNKELAISGLLAISDD 826 +MFP ++++VI+ +L GNK+ AI+ LL + ++ Sbjct: 239 DMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEE 273
>sp|Q9H0E2|TOLIP_HUMAN Toll-interacting protein Length = 274 Score = 169 bits (429), Expect = 8e-42 Identities = 100/275 (36%), Positives = 148/275 (53%), Gaps = 20/275 (7%) Frame = +2 Query: 62 SIEEKRKRCLLGELPDDFLRIPXXXXXXXXXXXXTSGMMYPQLQVMPAPXXXXXXXXXXX 241 ++ +R +GELP DFLRI + QLQ A Sbjct: 4 TVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQ---QLQYGGA--VGTVGRLNIT 58 Query: 242 XXXARLAKNYGITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHIS 421 A+LAKNYG+TRMDPYC++R+G+ YET TA NG+KNP WNK C +P GV++ ++ Sbjct: 59 VVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLE 118 Query: 422 IYDEKTMSADEEIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLS--IKEVQ 595 I+DE+ S D+ IA+ IT P + QG V D WY L+G+QG+++EG IN+V+S + Sbjct: 119 IFDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAA 178 Query: 596 MMQPP----TFPMPVRQMV------------TPGYVMPTQP--HVRPAPVITDADVDQIH 721 M+ PP P +Q V +PG V P V P ++ D+ I Sbjct: 179 MVMPPQPVVLMPTVYQQGVGYVPITGMPAVCSPGMVPVALPPAAVNAQPRCSEEDLKAIQ 238 Query: 722 EMFPTIEKKVIKDMLVENGGNKELAISGLLAISDD 826 +MFP ++++VI+ +L GNK+ AI+ LL + ++ Sbjct: 239 DMFPNMDQEVIRSVLEAQRGNKDAAINSLLQMGEE 273
>sp|Q9C8S6|Y1322_ARATH C2 domain protein At1g63220 Length = 147 Score = 43.9 bits (102), Expect = 7e-04 Identities = 24/104 (23%), Positives = 46/104 (44%) Frame = +2 Query: 275 ITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADE 454 + MDPY ++ + ++ A P WN+ F + +G + I+D+ + D+ Sbjct: 22 LNNMDPYVQLTCRTQDQKSNVAEGMGTTPEWNETFIFTVSEGTTELKAKIFDKDVGTEDD 81 Query: 455 EIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLSIK 586 + I P +G++ Y + + E +G+I V LS K Sbjct: 82 AVGEATIPLEPVFVEGSIPPTAYNVV--KDEEYKGEIWVALSFK 123
>sp|P93733|PLDB1_ARATH Phospholipase D beta 1 (AtPLDbeta1) (PLD beta 1) (PLDbeta) Length = 967 Score = 42.0 bits (97), Expect = 0.003 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 466 DPY V V + S+NP W + F+ P+ +H + D + + Sbjct: 200 DPYVSVSVAGAVIGRTYVMSNSENPVWMQHFYVPVAHHAAEVHFVVKDSDVVGSQ---LI 256 Query: 467 CVITFPPE-IFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQM 598 ++T P E I+ G I+ Y + G+ + N+ LSI+ M Sbjct: 257 GLVTIPVEQIYSGAKIEGTYPILTSNGKPCKPGANLSLSIQYTPM 301
>sp|O23078|PLDB2_ARATH Phospholipase D beta 2 (AtPLDbeta2) (PLD beta 2) (PLDdelta1) Length = 915 Score = 41.6 bits (96), Expect = 0.003 Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 1/105 (0%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 466 DPY + V + S+NP W + F+ P+ +H + D + + Sbjct: 161 DPYVSISVAGAVIGRTYVISNSENPVWQQHFYVPVAHHAAEVHFVVKDSDAVGSQ---LI 217 Query: 467 CVITFPPE-IFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQM 598 ++T P E I+ G I+ Y + G+ + + LSI+ M Sbjct: 218 GIVTIPVEQIYSGARIEGTYSIRDSNGKPCKPGATLSLSIQYTSM 262
>sp|O14065|YC31_SCHPO Hypothetical protein C962.01 in chromosome III Length = 1429 Score = 40.8 bits (94), Expect = 0.006 Identities = 26/111 (23%), Positives = 43/111 (38%), Gaps = 14/111 (12%) Frame = +2 Query: 281 RMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEI 460 + DPY +V VG+ + NP WN+ + PI +TI + D + D + Sbjct: 778 KSDPYARVIVGNSVVARTVYTPNNLNPIWNEILYVPIMADTKTIDLEAMDYEESGNDRSL 837 Query: 461 AFCVITFPPEIFQGNVID--------------NWYRLTGKQGENQEGQINV 571 + I I +D N LT ++G++ G I+V Sbjct: 838 GYASINVQKYIRNAKRLDRSALASTVFGTSEVNALTLTSRKGQSVRGTISV 888
>sp|Q8K0T7|UN13C_MOUSE Unc-13 homolog C (Munc13-3) Length = 1430 Score = 40.4 bits (93), Expect = 0.008 Identities = 19/49 (38%), Positives = 27/49 (55%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 433 DPY V+VG T T F G+ NP W++KFF + I + ++DE Sbjct: 1238 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFFFECHNSTDRIKVRVWDE 1285
>sp|Q62770|UN13C_RAT Unc-13 homolog C (Munc13-3) Length = 2204 Score = 39.3 bits (90), Expect = 0.017 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 433 DPY V+VG T T F G+ NP W++KF+ + I + ++DE Sbjct: 1232 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFYFECHNSTDRIKVRVWDE 1279
>sp|Q8NB66|UN13C_HUMAN Unc-13 homolog C (Munc13-3) Length = 1190 Score = 39.3 bits (90), Expect = 0.017 Identities = 18/49 (36%), Positives = 27/49 (55%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 433 DPY V+VG T T F G+ NP W++KF+ + I + ++DE Sbjct: 218 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFYFECHNSTDRIKVRVWDE 265
>sp|Q9Z268|RASL1_MOUSE RasGAP-activating-like protein 1 Length = 799 Score = 38.9 bits (89), Expect = 0.022 Identities = 27/116 (23%), Positives = 49/116 (42%) Frame = +2 Query: 287 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 466 DPYC V+V + S +P+W +++ +P + + DE T+ D+ I Sbjct: 27 DPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLDFHHLAFYVLDEDTVGHDDIIGK 86 Query: 467 CVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQMMQPPTFPMPVRQ 634 ++ ID+W L+ + + E Q V L +K ++ + VRQ Sbjct: 87 ISLSKEAITADPRGIDSWINLS-RVDPDAEVQGEVCLDVKLLEDARGRCLRCHVRQ 141
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 105,246,181 Number of Sequences: 369166 Number of extensions: 2144086 Number of successful extensions: 5472 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5248 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5466 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10144071740 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)