Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_I05
(913 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QZ06|TOLIP_MOUSE Toll-interacting protein 175 1e-43
sp|Q9H0E2|TOLIP_HUMAN Toll-interacting protein 169 8e-42
sp|Q9C8S6|Y1322_ARATH C2 domain protein At1g63220 44 6e-04
sp|P93733|PLDB1_ARATH Phospholipase D beta 1 (AtPLDbeta1) (... 42 0.002
sp|O23078|PLDB2_ARATH Phospholipase D beta 2 (AtPLDbeta2) (... 42 0.003
sp|O14065|YC31_SCHPO Hypothetical protein C962.01 in chromo... 41 0.005
sp|Q8K0T7|UN13C_MOUSE Unc-13 homolog C (Munc13-3) 40 0.007
sp|Q62770|UN13C_RAT Unc-13 homolog C (Munc13-3) 39 0.015
sp|Q8NB66|UN13C_HUMAN Unc-13 homolog C (Munc13-3) 39 0.015
sp|Q9Z268|RASL1_MOUSE RasGAP-activating-like protein 1 39 0.020
>sp|Q9QZ06|TOLIP_MOUSE Toll-interacting protein
Length = 274
Score = 175 bits (444), Expect = 1e-43
Identities = 100/275 (36%), Positives = 145/275 (52%), Gaps = 20/275 (7%)
Frame = +1
Query: 4 SIEEKRKRCLLGELPDDFLRIPXXXXXXXXXXXXTSGMMYPQLQVMPAPXXXXXXXXXXX 183
++ +R +GELP DFLRI + Q+
Sbjct: 4 TVSTQRGPVYIGELPQDFLRITPTQQQQQIQLDAQAAQ-----QLQYGGTVGTVGRLSIT 58
Query: 184 XXXARLAKNYGITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHIS 363
A+LAKNYG+TRMDPYC++R+G+ YET TA NG+KNP WNK C +P GV++ ++
Sbjct: 59 VVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIQCTVPPGVDSFYLE 118
Query: 364 IYDEKTMSADEEIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVL---SIKEV 534
I+DE+ S D+ IA+ IT P + QG V D WY L+G+QG+++EG IN+V+ S+
Sbjct: 119 IFDERAFSMDDRIAWTHITIPESLKQGQVEDEWYSLSGRQGDDKEGMINLVMSYTSLPAA 178
Query: 535 QMMQP-PTFPMPVRQMVTPGYV----MPT------------QPHVRPAPVITDADVDQIH 663
MM P P MP GYV MP P V P P + D+ I
Sbjct: 179 MMMPPQPVVLMPTVYQQGVGYVPIAGMPAVCSPGMVPMAMPPPAVAPQPRCNEEDLKAIQ 238
Query: 664 EMFPTIEKKVIKDMLVENGGNKELAISGLLAISDD 768
+MFP ++++VI+ +L GNK+ AI+ LL + ++
Sbjct: 239 DMFPNMDREVIRSVLEAQRGNKDAAINSLLQMGEE 273
>sp|Q9H0E2|TOLIP_HUMAN Toll-interacting protein
Length = 274
Score = 169 bits (429), Expect = 8e-42
Identities = 100/275 (36%), Positives = 148/275 (53%), Gaps = 20/275 (7%)
Frame = +1
Query: 4 SIEEKRKRCLLGELPDDFLRIPXXXXXXXXXXXXTSGMMYPQLQVMPAPXXXXXXXXXXX 183
++ +R +GELP DFLRI + QLQ A
Sbjct: 4 TVSTQRGPVYIGELPQDFLRITPTQQQRQVQLDAQAAQ---QLQYGGA--VGTVGRLNIT 58
Query: 184 XXXARLAKNYGITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHIS 363
A+LAKNYG+TRMDPYC++R+G+ YET TA NG+KNP WNK C +P GV++ ++
Sbjct: 59 VVQAKLAKNYGMTRMDPYCRLRLGYAVYETPTAHNGAKNPRWNKVIHCTVPPGVDSFYLE 118
Query: 364 IYDEKTMSADEEIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLS--IKEVQ 537
I+DE+ S D+ IA+ IT P + QG V D WY L+G+QG+++EG IN+V+S +
Sbjct: 119 IFDERAFSMDDRIAWTHITIPESLRQGKVEDKWYSLSGRQGDDKEGMINLVMSYALLPAA 178
Query: 538 MMQPP----TFPMPVRQMV------------TPGYVMPTQP--HVRPAPVITDADVDQIH 663
M+ PP P +Q V +PG V P V P ++ D+ I
Sbjct: 179 MVMPPQPVVLMPTVYQQGVGYVPITGMPAVCSPGMVPVALPPAAVNAQPRCSEEDLKAIQ 238
Query: 664 EMFPTIEKKVIKDMLVENGGNKELAISGLLAISDD 768
+MFP ++++VI+ +L GNK+ AI+ LL + ++
Sbjct: 239 DMFPNMDQEVIRSVLEAQRGNKDAAINSLLQMGEE 273
>sp|Q9C8S6|Y1322_ARATH C2 domain protein At1g63220
Length = 147
Score = 43.9 bits (102), Expect = 6e-04
Identities = 24/104 (23%), Positives = 46/104 (44%)
Frame = +1
Query: 217 ITRMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADE 396
+ MDPY ++ + ++ A P WN+ F + +G + I+D+ + D+
Sbjct: 22 LNNMDPYVQLTCRTQDQKSNVAEGMGTTPEWNETFIFTVSEGTTELKAKIFDKDVGTEDD 81
Query: 397 EIAFCVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLSIK 528
+ I P +G++ Y + + E +G+I V LS K
Sbjct: 82 AVGEATIPLEPVFVEGSIPPTAYNVV--KDEEYKGEIWVALSFK 123
>sp|P93733|PLDB1_ARATH Phospholipase D beta 1 (AtPLDbeta1) (PLD beta 1) (PLDbeta)
Length = 967
Score = 42.0 bits (97), Expect = 0.002
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 408
DPY V V + S+NP W + F+ P+ +H + D + +
Sbjct: 200 DPYVSVSVAGAVIGRTYVMSNSENPVWMQHFYVPVAHHAAEVHFVVKDSDVVGSQ---LI 256
Query: 409 CVITFPPE-IFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQM 540
++T P E I+ G I+ Y + G+ + N+ LSI+ M
Sbjct: 257 GLVTIPVEQIYSGAKIEGTYPILTSNGKPCKPGANLSLSIQYTPM 301
>sp|O23078|PLDB2_ARATH Phospholipase D beta 2 (AtPLDbeta2) (PLD beta 2) (PLDdelta1)
Length = 915
Score = 41.6 bits (96), Expect = 0.003
Identities = 24/105 (22%), Positives = 43/105 (40%), Gaps = 1/105 (0%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 408
DPY + V + S+NP W + F+ P+ +H + D + +
Sbjct: 161 DPYVSISVAGAVIGRTYVISNSENPVWQQHFYVPVAHHAAEVHFVVKDSDAVGSQ---LI 217
Query: 409 CVITFPPE-IFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQM 540
++T P E I+ G I+ Y + G+ + + LSI+ M
Sbjct: 218 GIVTIPVEQIYSGARIEGTYSIRDSNGKPCKPGATLSLSIQYTSM 262
>sp|O14065|YC31_SCHPO Hypothetical protein C962.01 in chromosome III
Length = 1429
Score = 40.8 bits (94), Expect = 0.005
Identities = 26/111 (23%), Positives = 43/111 (38%), Gaps = 14/111 (12%)
Frame = +1
Query: 223 RMDPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEI 402
+ DPY +V VG+ + NP WN+ + PI +TI + D + D +
Sbjct: 778 KSDPYARVIVGNSVVARTVYTPNNLNPIWNEILYVPIMADTKTIDLEAMDYEESGNDRSL 837
Query: 403 AFCVITFPPEIFQGNVID--------------NWYRLTGKQGENQEGQINV 513
+ I I +D N LT ++G++ G I+V
Sbjct: 838 GYASINVQKYIRNAKRLDRSALASTVFGTSEVNALTLTSRKGQSVRGTISV 888
>sp|Q8K0T7|UN13C_MOUSE Unc-13 homolog C (Munc13-3)
Length = 1430
Score = 40.4 bits (93), Expect = 0.007
Identities = 19/49 (38%), Positives = 27/49 (55%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 375
DPY V+VG T T F G+ NP W++KFF + I + ++DE
Sbjct: 1238 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFFFECHNSTDRIKVRVWDE 1285
>sp|Q62770|UN13C_RAT Unc-13 homolog C (Munc13-3)
Length = 2204
Score = 39.3 bits (90), Expect = 0.015
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 375
DPY V+VG T T F G+ NP W++KF+ + I + ++DE
Sbjct: 1232 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFYFECHNSTDRIKVRVWDE 1279
>sp|Q8NB66|UN13C_HUMAN Unc-13 homolog C (Munc13-3)
Length = 1190
Score = 39.3 bits (90), Expect = 0.015
Identities = 18/49 (36%), Positives = 27/49 (55%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDE 375
DPY V+VG T T F G+ NP W++KF+ + I + ++DE
Sbjct: 218 DPYVTVQVGKNKRRTKTIF-GNLNPVWDEKFYFECHNSTDRIKVRVWDE 265
>sp|Q9Z268|RASL1_MOUSE RasGAP-activating-like protein 1
Length = 799
Score = 38.9 bits (89), Expect = 0.020
Identities = 27/116 (23%), Positives = 49/116 (42%)
Frame = +1
Query: 229 DPYCKVRVGHKTYETVTAFNGSKNPYWNKKFFCPIPKGVETIHISIYDEKTMSADEEIAF 408
DPYC V+V + S +P+W +++ +P + + DE T+ D+ I
Sbjct: 27 DPYCLVKVDDQVVARTATIWRSLSPFWGEEYTVHLPLDFHHLAFYVLDEDTVGHDDIIGK 86
Query: 409 CVITFPPEIFQGNVIDNWYRLTGKQGENQEGQINVVLSIKEVQMMQPPTFPMPVRQ 576
++ ID+W L+ + + E Q V L +K ++ + VRQ
Sbjct: 87 ISLSKEAITADPRGIDSWINLS-RVDPDAEVQGEVCLDVKLLEDARGRCLRCHVRQ 141
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,656,875
Number of Sequences: 369166
Number of extensions: 2055043
Number of successful extensions: 5236
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5021
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5230
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9270587090
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)