Planaria EST Database


DrC_00507

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00507
         (894 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P10746|HEM4_HUMAN  Uroporphyrinogen-III synthase (UROS) (...   132   1e-30
sp|P51163|HEM4_MOUSE  Uroporphyrinogen-III synthase (UROS) (...   124   4e-28
sp|P06174|HEM4_YEAST  Uroporphyrinogen-III synthase (UROS) (...    82   3e-15
sp|P87214|HEM4_SCHPO  Uroporphyrinogen-III synthase (UROS) (...    72   2e-12
sp|Q10234|RT05_SCHPO  Probable mitochondrial 40S ribosomal p...    34   0.48 
sp|Q8TYR8|Y224_METKA  Hypothetical UPF0284 protein MK0224          34   0.63 
sp|P64192|G6PI_MYCTU  Glucose-6-phosphate isomerase (GPI) (P...    32   2.4  
sp|P96803|G6PI_MYCSM  Glucose-6-phosphate isomerase (GPI) (P...    32   2.4  
sp|Q12873|CHD3_HUMAN  Chromodomain helicase-DNA-binding prot...    32   3.1  
sp|Q9LFA3|MDA3_ARATH  Probable monodehydroascorbate reductas...    31   4.1  
>sp|P10746|HEM4_HUMAN Uroporphyrinogen-III synthase (UROS) (Uroporphyrinogen-III
           cosynthetase) (Hydroxymethylbilane hydrolyase
           [cyclizing]) (UROIIIS)
          Length = 265

 Score =  132 bits (332), Expect = 1e-30
 Identities = 82/247 (33%), Positives = 129/247 (52%), Gaps = 13/247 (5%)
 Frame = +2

Query: 8   EDPYVKVLMENNFNVSLIETLDFVFHPEELKSICSNYTQWYENFSAIIFTSPRAVQAFQM 187
           +DPY++ L       +LI  L F F    L S     +   E++  +IFTSPRAV+A ++
Sbjct: 16  QDPYIRELGLYGLEATLIPVLSFEFL--SLPSFSEKLSH-PEDYGGLIFTSPRAVEAAEL 72

Query: 188 SGLPASKNVV-------------CFVVGNATKALAESLGFETAGAESGNADVLLDTIVNY 328
                +K  V              +VVGNAT +L   +G +T G   GNA+ L + I + 
Sbjct: 73  CLEQNNKTEVWERSLKEKWNAKSVYVVGNATASLVSKIGLDTEGETCGNAEKLAEYICSR 132

Query: 329 DRNALTKPVLFPCGKMHRPVLPKKLEENGIQIKSVFVYSTKESVELSEKLKQLFTNSQNI 508
           + +AL  P+LFPCG + R +LPK L++ GI ++S+ VY T     +   L   ++  Q +
Sbjct: 133 ESSAL--PLLFPCGNLKREILPKALKDKGIAMESITVYQTVAHPGIQGNLNSYYSQ-QGV 189

Query: 509 PDLLVFFSPSGIAFSEKVLKDEIVSKHSHLKFGSMGPATSAQLTSSGFSVELESRSPKPE 688
           P  + FFSPSG+ +S K +++        +KF ++GP T+  L + G  V   + SP P+
Sbjct: 190 PASITFFSPSGLTYSLKHIQELSGDNIDQIKFAAIGPTTARALAAQGLPVSCTAESPTPQ 249

Query: 689 ALLKAIK 709
           AL   I+
Sbjct: 250 ALATGIR 256
>sp|P51163|HEM4_MOUSE Uroporphyrinogen-III synthase (UROS) (Uroporphyrinogen-III
           cosynthetase) (Hydroxymethylbilane hydrolyase
           [cyclizing]) (UROIIIS)
          Length = 265

 Score =  124 bits (311), Expect = 4e-28
 Identities = 81/249 (32%), Positives = 128/249 (51%), Gaps = 13/249 (5%)
 Frame = +2

Query: 11  DPYVKVLMENNFNVSLIETLDFVFHPEELKSICSNYTQWYENFSAIIFTSPRAVQAFQMS 190
           DPY++ L       +LI  L F F    L S+    +   E F  +IFTSPRAV+A ++ 
Sbjct: 17  DPYIQELRLCGLEATLIPVLSFEFM--SLPSLSEKLSH-PEGFGGLIFTSPRAVEAVKLC 73

Query: 191 GLPASKNVV-------------CFVVGNATKALAESLGFETAGAESGNADVLLDTIVNYD 331
               +K                 +VVG+AT +L   +G +  GA SGNA+ L + I +  
Sbjct: 74  LEKDNKTEAWEKSLKDRWNAKSVYVVGSATASLVNKIGLDAEGAGSGNAEKLAEYICSKP 133

Query: 332 RNALTKPVLFPCGKMHRPVLPKKLEENGIQIKSVFVYSTKESVELSEKLKQLFTNSQNIP 511
            + L  P+LFPCG +    LPK L++ GI ++S+ VY T     +   LK  + + Q IP
Sbjct: 134 SSEL--PLLFPCGTIKGDTLPKMLKDKGIPMESMHVYQTVPHPGIQGSLKSYYED-QGIP 190

Query: 512 DLLVFFSPSGIAFSEKVLKDEIVSKHSHLKFGSMGPATSAQLTSSGFSVELESRSPKPEA 691
             + FFSPSG+ +S + ++    S    +KF ++GP+T+  + + G  V   + SP P+A
Sbjct: 191 ASITFFSPSGLKYSLEYIQALSGSSFDQIKFIAIGPSTTRAMAAKGLPVSCTAESPTPQA 250

Query: 692 LLKAIKGLI 718
           L   I+ ++
Sbjct: 251 LAAGIRNVL 259
>sp|P06174|HEM4_YEAST Uroporphyrinogen-III synthase (UROS) (Uroporphyrinogen-III
           cosynthetase) (Hydroxymethylbilane hydrolyase
           [cyclizing]) (UROIIIS)
          Length = 275

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 63/229 (27%), Positives = 104/229 (45%), Gaps = 22/229 (9%)
 Frame = +2

Query: 89  EELKSICSNYTQWYENFSAIIFTSPRAVQAFQMSGLPA----------SKNVVCFVVGNA 238
           ++ +++ +    +    + II TS R V++   + +P           SK V  + VG A
Sbjct: 46  QDFRNVLNTIPNYLNTINYIIITSQRTVESLNEAIIPTLTSEQKAALLSKTV--YTVGPA 103

Query: 239 TKALAESLGF------ETAGAESGNADVLLDTIVNYDRNALTKPVLFPCGKMHRPVLPKK 400
           T       GF      E AG  S  AD+++D +    +      +LF  G++ R ++PKK
Sbjct: 104 TANFIRRSGFINVKGGEDAGNGSILADIIIDDLSTDIKACPPSELLFLVGEIRRDIIPKK 163

Query: 401 LEENGIQIKSVFVYSTKESVELSEKLKQLF------TNSQNIPDLLVFFSPSGIAFSEKV 562
           L   GI+++ V  Y T+   ELS+  K+           +   D +V FSP G     + 
Sbjct: 164 LHSKGIKVREVVTYKTE---ELSDGFKRFIHAMKECDEDEVFSDWVVVFSPQGTKEITQY 220

Query: 563 LKDEIVSKHSHLKFGSMGPATSAQLTSSGFSVELESRSPKPEALLKAIK 709
           L D      SHL+  S+GP T   L  +  + ++ S  P P++LL AI+
Sbjct: 221 LGDSNRLPGSHLRVASIGPTTKKYLDDNDVTSDVVSPKPDPKSLLDAIE 269
>sp|P87214|HEM4_SCHPO Uroporphyrinogen-III synthase (UROS) (Uroporphyrinogen-III
           cosynthetase) (Hydroxymethylbilane hydrolyase
           [cyclizing]) (UROIIIS)
          Length = 251

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 67/243 (27%), Positives = 106/243 (43%), Gaps = 11/243 (4%)
 Frame = +2

Query: 11  DPYVKVLMENNFNVSLIETLDFV-FHPEELKSICSNYTQWYENFSAIIFTSPRAVQ---- 175
           DPYV+   +   + + I  L     H E+L+    N  + Y     +I TS R  +    
Sbjct: 15  DPYVEAFEKYGRDTAFIPVLRHKRVHEEQLRDKLKNVRKTY---CGLIVTSQRVSETLDE 71

Query: 176 AFQMSGLPASKNVVC----FVVGNATKALAESLGFE-TAGAESGNADVLLDTIVN-YDRN 337
           A +       + ++     F VG AT      LGF+ T G + G  +VL D I   Y   
Sbjct: 72  ALKQEDETERQKILMETPIFTVGPATDDSIRRLGFQQTHGKDCGRGEVLADLIEEWYTTT 131

Query: 338 ALTKPVLFPCGKMHRPVLPKKLEENGIQIKSVFVYSTKESVELSEKLKQLFTNSQNIPDL 517
              KP+LF  G+ HR ++ +KL ++  ++ S+ VY+T+E      ++K        I D 
Sbjct: 132 KQHKPLLFLVGEKHRDIIQRKLGDD--RVDSLIVYATQELENTETQIKDTIRKHPTI-DW 188

Query: 518 LVFFSPSGIAFSEKVLKDEIVSKHSHLKFGSMGPATSAQLTSSGFSVELESRSPKPEALL 697
           +V FSP+ I       +         LK  ++GP T   L   G    + S +P PE+L 
Sbjct: 189 IVAFSPTSICSLLNTFE---------LKIATIGPTTGDYLKKLGTQPNVVSPAPNPESLA 239

Query: 698 KAI 706
            +I
Sbjct: 240 SSI 242
>sp|Q10234|RT05_SCHPO Probable mitochondrial 40S ribosomal protein S5
          Length = 387

 Score = 34.3 bits (77), Expect = 0.48
 Identities = 21/72 (29%), Positives = 33/72 (45%)
 Frame = +2

Query: 89  EELKSICSNYTQWYENFSAIIFTSPRAVQAFQMSGLPASKNVVCFVVGNATKALAESLGF 268
           EELKS   ++  +YEN+   I   P A++A Q S  P    +    V    K +    G+
Sbjct: 106 EELKSRFKDHLPFYENY---IRNHPLAIEALQKSTAPRQTGLKLNYVSKLDKYVTPLDGY 162

Query: 269 ETAGAESGNADV 304
              G+E  N ++
Sbjct: 163 SHLGSEESNGEI 174
>sp|Q8TYR8|Y224_METKA Hypothetical UPF0284 protein MK0224
          Length = 378

 Score = 33.9 bits (76), Expect = 0.63
 Identities = 37/142 (26%), Positives = 62/142 (43%), Gaps = 13/142 (9%)
 Frame = +2

Query: 263 GFETAGAESGNADV----------LLDTIVNYDRNALTKPVLFPCGKMHRPVLPKKLEEN 412
           G E  G E G+ D           ++  +V     + T PVL   G    P+L    EE 
Sbjct: 221 GLEAQGVEPGDLDAHEAIRRFGDPMMPAVVGIIYGSRT-PVLLAGGTQMAPILAYLAEEG 279

Query: 413 GIQIKSVFVYSTKESVELSEK-LKQLFTNSQNIPDLLVFFSPSGIAFSEKVLKDEIVSKH 589
            +  + VFV +TK  VE  +  ++ LF   + + D ++F +  G  FSE   +   + + 
Sbjct: 280 QLDPERVFVGTTKYVVEDEDSDIESLF---RQVGDYVLFSADPG--FSESKFRGFRLYEE 334

Query: 590 SHLK--FGSMGPATSAQLTSSG 649
            ++K   G+ G   +A L + G
Sbjct: 335 GYVKEGVGAGGAQVAAALKTKG 356
>sp|P64192|G6PI_MYCTU Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
 sp|P64193|G6PI_MYCBO Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
          Length = 553

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 16/50 (32%), Positives = 25/50 (50%)
 Frame = -1

Query: 405 SNFFGSTGRCILPQGNNTGLVKAFLS*FTIVSNKTSALPLSAPAVSNPND 256
           SNFFG+  R +LP  N+     A+L   T+ SN  S     +P  ++  +
Sbjct: 327 SNFFGAQSRTVLPYSNDLSRFPAYLQQLTMESNGKSTRADGSPVSADTGE 376
>sp|P96803|G6PI_MYCSM Glucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase)
           (PGI) (Phosphohexose isomerase) (PHI)
          Length = 442

 Score = 32.0 bits (71), Expect = 2.4
 Identities = 16/50 (32%), Positives = 24/50 (48%)
 Frame = -1

Query: 405 SNFFGSTGRCILPQGNNTGLVKAFLS*FTIVSNKTSALPLSAPAVSNPND 256
           SNFFG+  R +LP  N+     A+L   T+ SN  S      P  ++  +
Sbjct: 216 SNFFGAQSRAVLPYSNDLSRFAAYLQQLTMESNGKSVRADGTPVSTDTGE 265
>sp|Q12873|CHD3_HUMAN Chromodomain helicase-DNA-binding protein 3 (CHD-3) (Mi-2 autoantigen
            240 kDa protein) (Mi2-alpha)
          Length = 1944

 Score = 31.6 bits (70), Expect = 3.1
 Identities = 19/55 (34%), Positives = 22/55 (40%)
 Frame = +2

Query: 266  FETAGAESGNADVLLDTIVNYDRNALTKPVLFPCGKMHRPVLPKKLEENGIQIKS 430
            FE   +  G   V L  I+   +     P LFP   M  P LP    E G  IKS
Sbjct: 1004 FEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKS 1058
>sp|Q9LFA3|MDA3_ARATH Probable monodehydroascorbate reductase, cytoplasmic isoform 3
           (MDAR 3)
          Length = 434

 Score = 31.2 bits (69), Expect = 4.1
 Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 13/88 (14%)
 Frame = +2

Query: 200 ASKNVVCFVVGNATKALAESLGFETAGAESGNADVLL-DTIVNYDRNALTKPVLFPCGKM 376
           A K+    ++G    A   +  F   G + G   V+  + +  Y+R AL+K  LFP G  
Sbjct: 2   AEKSFKYIILGGGVSAGYAAKEFANQGVQPGELAVISKEAVAPYERPALSKGYLFPEGAA 61

Query: 377 HRP------------VLPKKLEENGIQI 424
             P            +LP+  ++ GI++
Sbjct: 62  RLPGFHCCVGSGGEKLLPESYKQKGIEL 89
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,723,227
Number of Sequences: 369166
Number of extensions: 1903060
Number of successful extensions: 4954
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4792
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4944
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00507

  1. Dr_sW_013_F23
  2. Dr_sW_012_F20