Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00502 (888 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O00458|IFRD1_HUMAN Interferon-related developmental regu... 95 3e-19 sp|Q5S1U6|IFRD1_PIG Interferon-related developmental regula... 95 3e-19 sp|P19182|IFRD1_MOUSE Interferon-related developmental regu... 92 2e-18 sp|P20695|IFRD1_RAT Interferon-related developmental regula... 87 6e-17 sp|Q12894|IFRD2_HUMAN Interferon-related developmental regu... 87 8e-17 sp|P51111|HD_RAT Huntingtin (Huntington's disease protein h... 32 2.4 sp|P39723|YAE7_YEAST Hypothetical 72.1 kDa protein in ACS1-... 32 3.1 sp|Q09807|PALA_SCHPO pH-response regulator protein palA/rim20 31 5.3 sp|Q92I35|SYL_RICCN Leucyl-tRNA synthetase (Leucine--tRNA l... 31 5.3 sp|P18458|R1AB_BEV Replicase polyprotein 1ab (pp1ab) (ORF1a... 30 6.9
>sp|O00458|IFRD1_HUMAN Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) Length = 451 Score = 94.7 bits (234), Expect = 3e-19 Identities = 69/236 (29%), Positives = 114/236 (48%), Gaps = 14/236 (5%) Frame = +3 Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179 FI + D ++ + LENIFT K Y+K L I+++ W+LL T Sbjct: 199 FIATDDITELYSTLECLENIFT-----KSYLKEKDTTVICSTPNTVLHISSLLAWTLLLT 253 Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359 I P + + LL + V++RI GE LAL+FE R I+ +F ++ ESL Sbjct: 254 ICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-IESDFFYEDMESL 312 Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539 + ++ L+ D K + K+D KQR FR +++++E F ++F E + I W + Sbjct: 313 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVE--ERDFPTETIKFGPERMYIDCWVK 370 Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707 K Y+ +++L G + N +R +F+L P+ D L K+S+ R N Sbjct: 371 KHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 426
>sp|Q5S1U6|IFRD1_PIG Interferon-related developmental regulator 1 Length = 450 Score = 94.7 bits (234), Expect = 3e-19 Identities = 70/236 (29%), Positives = 114/236 (48%), Gaps = 14/236 (5%) Frame = +3 Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179 FI + D ++ + LENIFT K Y+K L I+++ W+LL T Sbjct: 198 FIATDDITELYSTLQCLENIFT-----KSYLKEKDSNVICSTPNTALHISSLLAWTLLLT 252 Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359 I P + + LL + V++RI GE LAL+FE R ++ +F ++ ESL Sbjct: 253 ICPLSEVKKKLEMHVHKLPSLLSSDDVNMRIAAGESLALLFELARG-MESDFFYEDMESL 311 Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539 + ++ L+ D K + K+D KQR FR I++++E F ++F E + I W + Sbjct: 312 TQMLRALATDGNKHRAKVDKRKQRSVFRDILRAVEERD--FPTETVKFGPERMYIDCWVK 369 Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707 K Y+ ++IL G + N +R +F+L P+ D L K+S+ R N Sbjct: 370 KRTYDTFKEILGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 425
>sp|P19182|IFRD1_MOUSE Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) (TPA-induced sequence 7) (TIS7 protein) Length = 449 Score = 92.0 bits (227), Expect = 2e-18 Identities = 66/236 (27%), Positives = 114/236 (48%), Gaps = 14/236 (5%) Frame = +3 Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179 FI + D ++ + ENIFT K Y+K L I+++ W+LL T Sbjct: 197 FIATDDITELYSTLECFENIFT-----KSYLKEKDTNVTCSTPNTVLHISSLLAWTLLLT 251 Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359 I P + + LL + V++RI GE LAL+FE R ++ +F ++ +SL Sbjct: 252 ICPINEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-MESDFFYEDMDSL 310 Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539 + ++ L+ D K + K+D KQR FR +++++E F ++F E + I +W + Sbjct: 311 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERD--FPTETVKFGPERMYIDSWVK 368 Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707 K Y+ +++L G + N +R +F+L P+ D L K+S+ R N Sbjct: 369 KHTYDTFKEVLGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 424
>sp|P20695|IFRD1_RAT Interferon-related developmental regulator 1 (Nerve growth factor-inducible protein PC4) (IRPR) Length = 449 Score = 87.0 bits (214), Expect = 6e-17 Identities = 65/236 (27%), Positives = 111/236 (47%), Gaps = 14/236 (5%) Frame = +3 Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179 FI + D ++ + LE IFT K Y+K L I+++ W+LL T Sbjct: 197 FIATDDITELYSTLECLEGIFT-----KSYLKEKDTNVPCSTPNTVLHISSLLAWTLLLT 251 Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359 I P + LL + V++RI GE LAL+FE R ++ +F ++ +SL Sbjct: 252 ICPISEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-MESDFFYEDMDSL 310 Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539 + ++ L+ D K + K+D KQR FR +++++E F ++F E + I +W + Sbjct: 311 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVE--ERDFPTETVKFGPERMYIDSWVK 368 Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707 K Y+ ++ L G + N +R +F+L P+ D L K+ + R N Sbjct: 369 KHTYDTFKEALGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKIPRFERHLYN 424
>sp|Q12894|IFRD2_HUMAN Interferon-related developmental regulator 2 (SKMC15 protein) Length = 442 Score = 86.7 bits (213), Expect = 8e-17 Identities = 56/186 (30%), Positives = 96/186 (51%) Frame = +3 Query: 150 AIRCWSLLYTILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDP 329 A++ W+LL TI P + + R L LL SV++RI GE +AL+FE R +++ Sbjct: 238 ALQAWALLLTICPSTQISHILDRQLPRLPQLLSSESVNLRIAAGETIALLFELAR-DLEE 296 Query: 330 EFVCDNYESLIEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFEL 509 EFV ++ E+L ++ L+ D K + K D +QR FR ++ S+E + + ++F Sbjct: 297 EFVYEDMEALCSVLRTLATDSNKYRAKADRRRQRSTFRAVLHSVE--GGECEEEIVRFGF 354 Query: 510 EILSITNWTRKIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKT 689 E+L + +W R Y +++L G + N ++R+IF L L D L K+ + Sbjct: 355 EVLYMDSWARHRIYAAFKEVLGSGMHHHLQNNELLRDIFGLGPVLLLDATALKACKVPRF 414 Query: 690 VRRKQN 707 + N Sbjct: 415 EKHLYN 420
>sp|P51111|HD_RAT Huntingtin (Huntington's disease protein homolog) (HD protein) Length = 3110 Score = 32.0 bits (71), Expect = 2.4 Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 2/138 (1%) Frame = +3 Query: 33 SMFFIKSPDSLKIAKIMNLLENIFTVPSTEKYYIKLEINAIRCWSLLYTILPEHMLHNFG 212 ++F I +P SL+ + LL ++F PST +++ ++L ++ + Sbjct: 1607 TLFEILAPSSLRPVDM--LLRSMFITPSTMASVSTVQLWISGILAILRVLISQSTEDIVL 1664 Query: 213 SRILCLS-SDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYES-LIEKIKCLSV 386 SRI LS S L V R+R G+ + ER R + D + L++ + L Sbjct: 1665 SRIQELSFSPYLISCPVINRLRDGDSNPTLGERSRGKQVKNLPEDTFSRFLLQLVGILLE 1724 Query: 387 DYCKDKNKIDLAKQRHEF 440 D + K+D+++Q+H F Sbjct: 1725 DIVTKQLKVDMSEQQHTF 1742
>sp|P39723|YAE7_YEAST Hypothetical 72.1 kDa protein in ACS1-GCV3 intergenic region Length = 622 Score = 31.6 bits (70), Expect = 3.1 Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 13/126 (10%) Frame = +3 Query: 342 DNYESLIEK-IKCLSVDYCKD----KNKID-LAKQRHEFRLIIQSIES-------YSSKF 482 D+Y + +EK I L +D ++ +N++D L + ++ + + ++++ Y S F Sbjct: 412 DSYINDLEKQINDLQIDKSEEFHVIQNQLDKLDLENYQLKNQLNTLDNQKLILSQYESNF 471 Query: 483 TDFNMQFELEILSITNWTRKIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIR 662 FN L + SI +N +QKILQ+ + QF R ++ I + L+N + Sbjct: 472 IKFNQNLLLHLDSI--------FNILQKILQESSIAQFDRK--MKSIKSVPNALKN--LN 519 Query: 663 LLRKKL 680 L++ KL Sbjct: 520 LIQPKL 525
>sp|Q09807|PALA_SCHPO pH-response regulator protein palA/rim20 Length = 701 Score = 30.8 bits (68), Expect = 5.3 Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 3/114 (2%) Frame = +3 Query: 408 KIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFEL-EILSITNWTRKIHYNFIQKILQDGF 584 K + +QR +IIQ++E S F +Q E EI I +++++ + F Sbjct: 583 KWNFRRQRERQEIIIQNVEKLKSYLNSFKVQAECSEISKILSFSQETEKKY-------KF 635 Query: 585 LIQFRRN--NVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQNKLIERKIKRNH 740 L+Q RN + RE++++ I ++ S+ R +N+ KIK H Sbjct: 636 LLQTVRNETEIARELYNI--------ICRAEERYSQYENRYENENRLNKIKLQH 681
>sp|Q92I35|SYL_RICCN Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS) Length = 835 Score = 30.8 bits (68), Expect = 5.3 Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 10/119 (8%) Frame = +3 Query: 402 KNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTRKIHYN---FIQKIL 572 K+KID+ RH F +++Q + + T+ Q + N R + + F + +L Sbjct: 718 KDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQ------KLGNKERLYNLSFPAFDESML 771 Query: 573 Q-DGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQNK------LIERKI 728 + D +++ + N +R+ ++ + + D+I+ + L K + + K L+ RKI Sbjct: 772 ELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRKI 830
>sp|P18458|R1AB_BEV Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes: Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains: RNA-directed RNA polymerase (RdRp) (Pol); Helicase (Hel)] Length = 2291 Score = 30.4 bits (67), Expect = 6.9 Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 10/150 (6%) Frame = +3 Query: 39 FFIKSPDSLKIAKIMNLLENIFTVPSTEKYYIKLEINAIRCWSL---------LYTILPE 191 F P++LKI N + T+ T+ ++ + WS + I + Sbjct: 679 FIFSKPEALKIFTCENFSNKLQTILHTK-------VDQTKSWSTKGHIEEFCSAHIIKTD 731 Query: 192 HMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFER-MRNEIDPEFVCDNYESLIEK 368 H SR L+S L+ DV I +A++ E + + PEF ++ ++K Sbjct: 732 GEYHFLPSRGRLLASLLILDKLSDVDIYYMRFVAILCESAVYSRYQPEFFNGLFQVFLDK 791 Query: 369 IKCLSVDYCKDKNKIDLAKQRHEFRLIIQS 458 ++ DYC D L ++ L+ S Sbjct: 792 VQQFRKDYCCDPCPPQLLEREFYENLVFTS 821
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,394,041 Number of Sequences: 369166 Number of extensions: 1689200 Number of successful extensions: 4336 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4196 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4324 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8886314050 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)