Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_013_E16
(839 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O00458|IFRD1_HUMAN Interferon-related developmental regu... 95 3e-19
sp|Q5S1U6|IFRD1_PIG Interferon-related developmental regula... 95 3e-19
sp|P19182|IFRD1_MOUSE Interferon-related developmental regu... 92 2e-18
sp|P20695|IFRD1_RAT Interferon-related developmental regula... 87 6e-17
sp|Q12894|IFRD2_HUMAN Interferon-related developmental regu... 87 7e-17
sp|P51111|HD_RAT Huntingtin (Huntington's disease protein h... 32 2.2
sp|P39723|YAE7_YEAST Hypothetical 72.1 kDa protein in ACS1-... 32 2.9
sp|Q09807|PALA_SCHPO pH-response regulator protein palA/rim20 31 4.9
sp|Q92I35|SYL_RICCN Leucyl-tRNA synthetase (Leucine--tRNA l... 31 4.9
sp|P18458|R1AB_BEV Replicase polyprotein 1ab (pp1ab) (ORF1a... 30 6.4
>sp|O00458|IFRD1_HUMAN Interferon-related developmental regulator 1 (Nerve growth
factor-inducible protein PC4)
Length = 451
Score = 94.7 bits (234), Expect = 3e-19
Identities = 69/236 (29%), Positives = 114/236 (48%), Gaps = 14/236 (5%)
Frame = +3
Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179
FI + D ++ + LENIFT K Y+K L I+++ W+LL T
Sbjct: 199 FIATDDITELYSTLECLENIFT-----KSYLKEKDTTVICSTPNTVLHISSLLAWTLLLT 253
Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359
I P + + LL + V++RI GE LAL+FE R I+ +F ++ ESL
Sbjct: 254 ICPINEVKKKLEMHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-IESDFFYEDMESL 312
Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539
+ ++ L+ D K + K+D KQR FR +++++E F ++F E + I W +
Sbjct: 313 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVE--ERDFPTETIKFGPERMYIDCWVK 370
Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707
K Y+ +++L G + N +R +F+L P+ D L K+S+ R N
Sbjct: 371 KHTYDTFKEVLGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 426
>sp|Q5S1U6|IFRD1_PIG Interferon-related developmental regulator 1
Length = 450
Score = 94.7 bits (234), Expect = 3e-19
Identities = 70/236 (29%), Positives = 114/236 (48%), Gaps = 14/236 (5%)
Frame = +3
Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179
FI + D ++ + LENIFT K Y+K L I+++ W+LL T
Sbjct: 198 FIATDDITELYSTLQCLENIFT-----KSYLKEKDSNVICSTPNTALHISSLLAWTLLLT 252
Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359
I P + + LL + V++RI GE LAL+FE R ++ +F ++ ESL
Sbjct: 253 ICPLSEVKKKLEMHVHKLPSLLSSDDVNMRIAAGESLALLFELARG-MESDFFYEDMESL 311
Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539
+ ++ L+ D K + K+D KQR FR I++++E F ++F E + I W +
Sbjct: 312 TQMLRALATDGNKHRAKVDKRKQRSVFRDILRAVEERD--FPTETVKFGPERMYIDCWVK 369
Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707
K Y+ ++IL G + N +R +F+L P+ D L K+S+ R N
Sbjct: 370 KRTYDTFKEILGSGMQYHLQSNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 425
>sp|P19182|IFRD1_MOUSE Interferon-related developmental regulator 1 (Nerve growth
factor-inducible protein PC4) (TPA-induced sequence 7)
(TIS7 protein)
Length = 449
Score = 92.0 bits (227), Expect = 2e-18
Identities = 66/236 (27%), Positives = 114/236 (48%), Gaps = 14/236 (5%)
Frame = +3
Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179
FI + D ++ + ENIFT K Y+K L I+++ W+LL T
Sbjct: 197 FIATDDITELYSTLECFENIFT-----KSYLKEKDTNVTCSTPNTVLHISSLLAWTLLLT 251
Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359
I P + + LL + V++RI GE LAL+FE R ++ +F ++ +SL
Sbjct: 252 ICPINEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-MESDFFYEDMDSL 310
Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539
+ ++ L+ D K + K+D KQR FR +++++E F ++F E + I +W +
Sbjct: 311 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVEERD--FPTETVKFGPERMYIDSWVK 368
Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707
K Y+ +++L G + N +R +F+L P+ D L K+S+ R N
Sbjct: 369 KHTYDTFKEVLGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKISRFERHLYN 424
>sp|P20695|IFRD1_RAT Interferon-related developmental regulator 1 (Nerve growth
factor-inducible protein PC4) (IRPR)
Length = 449
Score = 87.0 bits (214), Expect = 6e-17
Identities = 65/236 (27%), Positives = 111/236 (47%), Gaps = 14/236 (5%)
Frame = +3
Query: 42 FIKSPDSLKIAKIMNLLENIFTVPSTEKYYIK--------------LEINAIRCWSLLYT 179
FI + D ++ + LE IFT K Y+K L I+++ W+LL T
Sbjct: 197 FIATDDITELYSTLECLEGIFT-----KSYLKEKDTNVPCSTPNTVLHISSLLAWTLLLT 251
Query: 180 ILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYESL 359
I P + LL + V++RI GE LAL+FE R ++ +F ++ +SL
Sbjct: 252 ICPISEVKKKLELHFHKLPSLLSCDDVNMRIAAGESLALLFELARG-MESDFFYEDMDSL 310
Query: 360 IEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTR 539
+ ++ L+ D K + K+D KQR FR +++++E F ++F E + I +W +
Sbjct: 311 TQMLRALATDGNKHRAKVDKRKQRSVFRDVLRAVE--ERDFPTETVKFGPERMYIDSWVK 368
Query: 540 KIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQN 707
K Y+ ++ L G + N +R +F+L P+ D L K+ + R N
Sbjct: 369 KHTYDTFKEALGSGMQYHLQTNEFLRNVFELGPPVMLDAATLKTMKIPRFERHLYN 424
>sp|Q12894|IFRD2_HUMAN Interferon-related developmental regulator 2 (SKMC15 protein)
Length = 442
Score = 86.7 bits (213), Expect = 7e-17
Identities = 56/186 (30%), Positives = 96/186 (51%)
Frame = +3
Query: 150 AIRCWSLLYTILPEHMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFERMRNEIDP 329
A++ W+LL TI P + + R L LL SV++RI GE +AL+FE R +++
Sbjct: 238 ALQAWALLLTICPSTQISHILDRQLPRLPQLLSSESVNLRIAAGETIALLFELAR-DLEE 296
Query: 330 EFVCDNYESLIEKIKCLSVDYCKDKNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFEL 509
EFV ++ E+L ++ L+ D K + K D +QR FR ++ S+E + + ++F
Sbjct: 297 EFVYEDMEALCSVLRTLATDSNKYRAKADRRRQRSTFRAVLHSVE--GGECEEEIVRFGF 354
Query: 510 EILSITNWTRKIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKT 689
E+L + +W R Y +++L G + N ++R+IF L L D L K+ +
Sbjct: 355 EVLYMDSWARHRIYAAFKEVLGSGMHHHLQNNELLRDIFGLGPVLLLDATALKACKVPRF 414
Query: 690 VRRKQN 707
+ N
Sbjct: 415 EKHLYN 420
>sp|P51111|HD_RAT Huntingtin (Huntington's disease protein homolog) (HD protein)
Length = 3110
Score = 32.0 bits (71), Expect = 2.2
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Frame = +3
Query: 33 SMFFIKSPDSLKIAKIMNLLENIFTVPSTEKYYIKLEINAIRCWSLLYTILPEHMLHNFG 212
++F I +P SL+ + LL ++F PST +++ ++L ++ +
Sbjct: 1607 TLFEILAPSSLRPVDM--LLRSMFITPSTMASVSTVQLWISGILAILRVLISQSTEDIVL 1664
Query: 213 SRILCLS-SDLLDRNSVDVRIRVGECLALIFERMRNEIDPEFVCDNYES-LIEKIKCLSV 386
SRI LS S L V R+R G+ + ER R + D + L++ + L
Sbjct: 1665 SRIQELSFSPYLISCPVINRLRDGDSNPTLGERSRGKQVKNLPEDTFSRFLLQLVGILLE 1724
Query: 387 DYCKDKNKIDLAKQRHEF 440
D + K+D+++Q+H F
Sbjct: 1725 DIVTKQLKVDMSEQQHTF 1742
>sp|P39723|YAE7_YEAST Hypothetical 72.1 kDa protein in ACS1-GCV3 intergenic region
Length = 622
Score = 31.6 bits (70), Expect = 2.9
Identities = 33/126 (26%), Positives = 63/126 (50%), Gaps = 13/126 (10%)
Frame = +3
Query: 342 DNYESLIEK-IKCLSVDYCKD----KNKID-LAKQRHEFRLIIQSIES-------YSSKF 482
D+Y + +EK I L +D ++ +N++D L + ++ + + ++++ Y S F
Sbjct: 412 DSYINDLEKQINDLQIDKSEEFHVIQNQLDKLDLENYQLKNQLNTLDNQKLILSQYESNF 471
Query: 483 TDFNMQFELEILSITNWTRKIHYNFIQKILQDGFLIQFRRNNVIREIFDLELPLRNDQIR 662
FN L + SI +N +QKILQ+ + QF R ++ I + L+N +
Sbjct: 472 IKFNQNLLLHLDSI--------FNILQKILQESSIAQFDRK--MKSIKSVPNALKN--LN 519
Query: 663 LLRKKL 680
L++ KL
Sbjct: 520 LIQPKL 525
>sp|Q09807|PALA_SCHPO pH-response regulator protein palA/rim20
Length = 701
Score = 30.8 bits (68), Expect = 4.9
Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 3/114 (2%)
Frame = +3
Query: 408 KIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFEL-EILSITNWTRKIHYNFIQKILQDGF 584
K + +QR +IIQ++E S F +Q E EI I +++++ + F
Sbjct: 583 KWNFRRQRERQEIIIQNVEKLKSYLNSFKVQAECSEISKILSFSQETEKKY-------KF 635
Query: 585 LIQFRRN--NVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQNKLIERKIKRNH 740
L+Q RN + RE++++ I ++ S+ R +N+ KIK H
Sbjct: 636 LLQTVRNETEIARELYNI--------ICRAEERYSQYENRYENENRLNKIKLQH 681
>sp|Q92I35|SYL_RICCN Leucyl-tRNA synthetase (Leucine--tRNA ligase) (LeuRS)
Length = 835
Score = 30.8 bits (68), Expect = 4.9
Identities = 26/119 (21%), Positives = 56/119 (47%), Gaps = 10/119 (8%)
Frame = +3
Query: 402 KNKIDLAKQRHEFRLIIQSIESYSSKFTDFNMQFELEILSITNWTRKIHYN---FIQKIL 572
K+KID+ RH F +++Q + + T+ Q + N R + + F + +L
Sbjct: 718 KDKIDVKTVRHGFNVLVQLLNPFIPHITEEIWQ------KLGNKERLYNLSFPAFDESML 771
Query: 573 Q-DGFLIQFRRNNVIREIFDLELPLRNDQIRLLRKKLSKTVRRKQNK------LIERKI 728
+ D +++ + N +R+ ++ + + D+I+ + L K + + K L+ RKI
Sbjct: 772 ELDTYIMAVQVNGKLRDTYEFKTSVSEDEIKQVTVSLPKVQKFLEGKEPKKIILVPRKI 830
>sp|P18458|R1AB_BEV Replicase polyprotein 1ab (pp1ab) (ORF1ab polyprotein) [Includes:
Replicase polyprotein 1a (pp1a) (ORF1a)] [Contains:
RNA-directed RNA polymerase (RdRp) (Pol); Helicase (Hel)]
Length = 2291
Score = 30.4 bits (67), Expect = 6.4
Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 10/150 (6%)
Frame = +3
Query: 39 FFIKSPDSLKIAKIMNLLENIFTVPSTEKYYIKLEINAIRCWSL---------LYTILPE 191
F P++LKI N + T+ T+ ++ + WS + I +
Sbjct: 679 FIFSKPEALKIFTCENFSNKLQTILHTK-------VDQTKSWSTKGHIEEFCSAHIIKTD 731
Query: 192 HMLHNFGSRILCLSSDLLDRNSVDVRIRVGECLALIFER-MRNEIDPEFVCDNYESLIEK 368
H SR L+S L+ DV I +A++ E + + PEF ++ ++K
Sbjct: 732 GEYHFLPSRGRLLASLLILDKLSDVDIYYMRFVAILCESAVYSRYQPEFFNGLFQVFLDK 791
Query: 369 IKCLSVDYCKDKNKIDLAKQRHEFRLIIQS 458
++ DYC D L ++ L+ S
Sbjct: 792 VQQFRKDYCCDPCPPQLLEREFYENLVFTS 821
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,572,569
Number of Sequences: 369166
Number of extensions: 1637188
Number of successful extensions: 4280
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4146
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4268
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8197207050
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)