DrC_00501
- Cluster detail
- GO Category : Not Available
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00501 (682 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O35129|PHB2_MOUSE Prohibitin-2 (B-cell receptor-associat... 204 2e-52 sp|Q5XIH7|PHB2_RAT Prohibitin-2 (B-cell receptor-associated... 204 2e-52 sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex prote... 195 8e-50 sp|P50085|PHB2_YEAST Prohibitin-2 183 3e-46 sp|P40961|PHB_YEAST Prohibitin 169 5e-42 sp|P67778|PHB_MOUSE Prohibitin (B-cell receptor associated ... 167 2e-41 sp|P35232|PHB_HUMAN Prohibitin 166 5e-41 sp|P24156|L2CC_DROME L(2)37Cc protein 155 7e-38 sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex prote... 149 7e-36 sp|O28852|Y1420_ARCFU Hypothetical protein AF1420 38 0.021
>sp|O35129|PHB2_MOUSE Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity) sp|Q99623|PHB2_HUMAN Prohibitin-2 (B-cell receptor-associated protein BAP37) (Repressor of estrogen receptor activity) (D-prohibitin) Length = 299 Score = 204 bits (519), Expect = 2e-52 Identities = 108/173 (62%), Positives = 140/173 (80%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQMVNISLRVLSRP+ ++P++Y+ LG DY+ERVLPSI NEVLK+VVAKFNA QLIT Sbjct: 96 SKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLIT 155 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFS++Y+ AVE KQ++QQEAQRAQF V Sbjct: 156 QRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVE 215 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCRKNRKNSVNS 536 +AKQE++QKIV AEG + + + L S++ GY+KLRKI++ + K S Sbjct: 216 KAKQEQRQKIVQAEGEAEAAKMLGEAL-SKNPGYIKLRKIRAAQNISKTIATS 267
>sp|Q5XIH7|PHB2_RAT Prohibitin-2 (B-cell receptor-associated protein BAP37) (BAP-37) Length = 299 Score = 204 bits (519), Expect = 2e-52 Identities = 108/173 (62%), Positives = 140/173 (80%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQMVNISLRVLSRP+ ++P++Y+ LG DY+ERVLPSI NEVLK+VVAKFNA QLIT Sbjct: 96 SKDLQMVNISLRVLSRPNAQELPSMYQRLGLDYEERVLPSIVNEVLKSVVAKFNASQLIT 155 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QR QVSLLIR+ L ERAKDF++I+DDV+IT+LSFS++Y+ AVE KQ++QQEAQRAQF V Sbjct: 156 QRAQVSLLIRRELTERAKDFSLILDDVAITELSFSREYTAAVEAKQVAQQEAQRAQFLVE 215 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCRKNRKNSVNS 536 +AKQE++QKIV AEG + + + L S++ GY+KLRKI++ + K S Sbjct: 216 KAKQEQRQKIVQAEGEAEAAKMLGEAL-SKNPGYIKLRKIRAAQNISKTIATS 267
>sp|P50093|PHB2_CAEEL Mitochondrial prohibitin complex protein 2 (Prohibitin-2) Length = 286 Score = 195 bits (496), Expect = 8e-50 Identities = 103/165 (62%), Positives = 131/165 (79%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQMVNI LRVLSRP+ + IY++LG++++ERVLPSI NEVLK VVAKFNA QLIT Sbjct: 87 SKDLQMVNIGLRVLSRPNPEHLVHIYRTLGQNWEERVLPSICNEVLKGVVAKFNASQLIT 146 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QR+QVS+L+RK LIERA DFNII+DDVS+T+L+FS QYS AVE KQ++ QEAQRA F V Sbjct: 147 QRQQVSMLVRKTLIERALDFNIILDDVSLTELAFSPQYSAAVEAKQVAAQEAQRATFYVE 206 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCRK 512 RAKQ++Q+KIV AEG + S + + G+LKLRKI++ +K Sbjct: 207 RAKQQKQEKIVQAEGEAESAKLLGEAM-KNDPGFLKLRKIRAAQK 250
Score = 40.4 bits (93), Expect = 0.004
Identities = 25/70 (35%), Positives = 39/70 (55%)
Frame = +1
Query: 388 KKDSRKLLMLRGEAQAAILIG*CFGRKVPVI*N*GK*KAAEKIARTLSTAQNKAYLNANT 567
++ K++ GEA++A L+G + P K +AA+KIAR +S + NK YL
Sbjct: 210 QQKQEKIVQAEGEAESAKLLGEAM-KNDPGFLKLRKIRAAQKIARIVSESGNKTYLPTGG 268
Query: 568 LMMNINDKTF 597
LM+NI D +
Sbjct: 269 LMLNIADTDY 278
>sp|P50085|PHB2_YEAST Prohibitin-2 Length = 315 Score = 183 bits (465), Expect = 3e-46 Identities = 94/162 (58%), Positives = 129/162 (79%) Frame = +3 Query: 24 DLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLITQR 203 DLQMVNI+ RVLSRPD+ ++PTIY++LG+DYDERVLPSI NEVLKAVVA+FNA QLITQR Sbjct: 115 DLQMVNITCRVLSRPDVVQLPTIYRTLGQDYDERVLPSIVNEVLKAVVAQFNASQLITQR 174 Query: 204 EQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVMRA 383 E+VS LIR+ L+ RA FNI++DDVSIT ++FS +++ AVE KQI+QQ+AQRA F V +A Sbjct: 175 EKVSRLIRENLVRRASKFNILLDDVSITYMTFSPEFTNAVEAKQIAQQDAQRAAFVVDKA 234 Query: 384 KQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCR 509 +QE+Q +V A+G + S + + +S Y++L+++ + R Sbjct: 235 RQEKQGMVVRAQGEAKSAELIGEAI-KKSRDYVELKRLDTAR 275
>sp|P40961|PHB_YEAST Prohibitin Length = 287 Score = 169 bits (429), Expect = 5e-42 Identities = 86/178 (48%), Positives = 129/178 (72%) Frame = +3 Query: 6 TNSQNSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAG 185 TN+ DLQMV+++LRVL RP++ ++P IY++LG DYDERVLPSI NEVLK++VA+F+A Sbjct: 80 TNTGTKDLQMVSLTLRVLHRPEVLQLPAIYQNLGLDYDERVLPSIGNEVLKSIVAQFDAA 139 Query: 186 QLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQ 365 +LITQRE +S IRK L RA +F I ++DVSIT ++F ++++AVE+KQI+QQ+A+RA+ Sbjct: 140 ELITQREIISQKIRKELSTRANEFGIKLEDVSITHMTFGPEFTKAVEQKQIAQQDAERAK 199 Query: 366 FTVMRAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCRKNRKNSVNSA 539 F V +A+QERQ ++ AEG + S L G L +R++++ + + NS+ Sbjct: 200 FLVEKAEQERQASVIRAEGEAESAEFISKALAKVGDGLLLIRRLEASKDIAQTLANSS 257
>sp|P67778|PHB_MOUSE Prohibitin (B-cell receptor associated protein 32) (BAP 32) sp|P67779|PHB_RAT Prohibitin Length = 272 Score = 167 bits (424), Expect = 2e-41 Identities = 84/162 (51%), Positives = 124/162 (76%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQ VNI+LR+L RP +++P IY S+GEDYDERVLPSI+ E+LK+VVA+F+AG+LIT Sbjct: 82 SKDLQNVNITLRILFRPVASQLPRIYTSIGEDYDERVLPSITTEILKSVVARFDAGELIT 141 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QRE VS + L ERA F +I+DDVS+T L+F K+++EAVE KQ++QQEA+RA+F V Sbjct: 142 QRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVE 201 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKS 503 +A+Q+++ I++AEG S + + L + G ++LRK+++ Sbjct: 202 KAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEA 243
>sp|P35232|PHB_HUMAN Prohibitin Length = 272 Score = 166 bits (420), Expect = 5e-41 Identities = 83/162 (51%), Positives = 124/162 (76%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQ VNI+LR+L RP +++P I+ S+GEDYDERVLPSI+ E+LK+VVA+F+AG+LIT Sbjct: 82 SKDLQNVNITLRILFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELIT 141 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QRE VS + L ERA F +I+DDVS+T L+F K+++EAVE KQ++QQEA+RA+F V Sbjct: 142 QRELVSRQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVE 201 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKS 503 +A+Q+++ I++AEG S + + L + G ++LRK+++ Sbjct: 202 KAEQQKKAAIISAEGDSKAAELIANSLATAGDGLIELRKLEA 243
>sp|P24156|L2CC_DROME L(2)37Cc protein Length = 276 Score = 155 bits (393), Expect = 7e-38 Identities = 79/162 (48%), Positives = 119/162 (73%) Frame = +3 Query: 18 NSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAGQLIT 197 + DLQ VNI+LR+L RP +++P IY LG+DYDERVLPSI+ EVLKAVVA+F+AG+LIT Sbjct: 82 SKDLQNVNITLRILYRPIPDQLPKIYTILGQDYDERVLPSIAPEVLKAVVAQFDAGELIT 141 Query: 198 QREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVM 377 QRE VS + + L RAK F I+DD+S+T L+F ++++ AVE KQ++QQEA++A+F V Sbjct: 142 QREMVSQRVSQELTVRAKQFGFILDDISLTHLTFGREFTLAVEMKQVAQQEAEKARFVVE 201 Query: 378 RAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKS 503 +A+Q++ I++AEG + + + G ++LR+I++ Sbjct: 202 KAEQQKLASIISAEGDAEAAGLLAKSFGEAGDGLVELRRIEA 243
>sp|Q9BKU4|PHB1_CAEEL Mitochondrial prohibitin complex protein 1 (Prohibitin-1) Length = 275 Score = 149 bits (376), Expect = 7e-36 Identities = 77/169 (45%), Positives = 119/169 (70%) Frame = +3 Query: 6 TNSQNSDLQMVNISLRVLSRPDINKIPTIYKSLGEDYDERVLPSISNEVLKAVVAKFNAG 185 T + + DLQ VNI+LR+L RP +++P IY ++G DY ERVLPSI+NEVLKAVVA+F+A Sbjct: 81 TITGSKDLQNVNITLRILHRPSPDRLPNIYLNIGLDYAERVLPSITNEVLKAVVAQFDAH 140 Query: 186 QLITQREQVSLLIRKLLIERAKDFNIIVDDVSITDLSFSKQYSEAVERKQISQQEAQRAQ 365 ++ITQRE VS L ERA F +++DD++IT L+F ++++EAVE KQ++QQEA++A+ Sbjct: 141 EMITQREVVSQRASVALRERAAQFGLLLDDIAITHLNFGREFTEAVEMKQVAQQEAEKAR 200 Query: 366 FTVMRAKQERQQKIVNAEGRSASCNIDWVMLWSQSSGYLKLRKIKSCRK 512 + V +A+Q + + AEG + + + S G ++LRKI++ + Sbjct: 201 YLVEKAEQMKIAAVTTAEGDAQAAKLLAKAFASAGDGLVELRKIEAAEE 249
>sp|O28852|Y1420_ARCFU Hypothetical protein AF1420 Length = 249 Score = 38.1 bits (87), Expect = 0.021 Identities = 30/139 (21%), Positives = 72/139 (51%), Gaps = 3/139 (2%) Frame = +3 Query: 96 KSLGEDYD-ERVLPSISNEVLKAVVAKFNAGQLITQREQVSLLIRKLLIERAKDFNIIVD 272 K++ E +D + ++ L++++ + +++++R+++++ +++++ E + I V Sbjct: 95 KAVTEVFDYQYATAQLAQTTLRSIIGQAELDEVLSERDKLNVKLQQIIDEETNPWGIKVT 154 Query: 273 DVSITDLSFSKQYSEAVERKQISQQEAQRAQFTVMRAKQERQQKIVNAEG--RSASCNID 446 V I D+ + E + R Q EA+R ER+ KI+ AEG ++A + Sbjct: 155 AVEIKDV----ELPEEMRRIMAMQAEAER----------ERRSKIIRAEGEYQAAMKLRE 200 Query: 447 WVMLWSQSSGYLKLRKIKS 503 + +QS G + LR +++ Sbjct: 201 AADVLAQSEGAILLRYLQT 219
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,690,168
Number of Sequences: 369166
Number of extensions: 884167
Number of successful extensions: 3148
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3010
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3141
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5782011865
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
