Planaria EST Database

DrC_00490

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00490
         (935 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Y6W6|DUS10_HUMAN  Dual specificity protein phosphatase ...   165   2e-40
sp|Q9ESS0|DUS10_MOUSE  Dual specificity protein phosphatase ...   165   2e-40
sp|Q05923|DUS2_HUMAN  Dual specificity protein phosphatase 2...   115   2e-25
sp|Q16828|DUS6_HUMAN  Dual specificity protein phosphatase 6...   115   2e-25
sp|Q64346|DUS6_RAT  Dual specificity protein phosphatase 6 (...   115   2e-25
sp|Q9DBB1|DUS6_MOUSE  Dual specificity protein phosphatase 6...   115   2e-25
sp|Q05922|DUS2_MOUSE  Dual specificity protein phosphatase 2...   115   2e-25
sp|P28562|DUS1_HUMAN  Dual specificity protein phosphatase 1...   113   7e-25
sp|Q99956|DUS9_HUMAN  Dual specificity protein phosphatase 9...   113   9e-25
sp|Q16829|DUS7_HUMAN  Dual specificity protein phosphatase 7...   111   3e-24

>sp|Q9Y6W6|DUS10_HUMAN Dual specificity protein phosphatase 10 (Mitogen-activated protein
           kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)
          Length = 482

 Score =  165 bits (417), Expect = 2e-40
 Identities = 79/154 (51%), Positives = 109/154 (70%), Gaps = 2/154 (1%)
 Frame = +1

Query: 127 DVLNATISEILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVPFYRED--LFIYKRLSA 300
           D+ NA ++ ILPFLFLGNE D+ D++ +Q   I +++NVTT++P Y  +  LF YKRL A
Sbjct: 316 DIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPA 375

Query: 301 TDCNKQDMRAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTI 480
           TD NKQ++R Y+ EA +FI+EA+     +L+HC AGVSRSATIV AYL+KHT++ +    
Sbjct: 376 TDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 435

Query: 481 TFLQSKRPIVEPNFNFLGQLERYYCDLERGVESR 582
            F++ KRPI+ PN NF+GQL  +  DL  GV  R
Sbjct: 436 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPR 469

>sp|Q9ESS0|DUS10_MOUSE Dual specificity protein phosphatase 10 (Mitogen-activated protein
           kinase phosphatase 5) (MAP kinase phosphatase 5) (MKP-5)
          Length = 483

 Score =  165 bits (417), Expect = 2e-40
 Identities = 79/154 (51%), Positives = 109/154 (70%), Gaps = 2/154 (1%)
 Frame = +1

Query: 127 DVLNATISEILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVPFYRED--LFIYKRLSA 300
           D+ NA ++ ILPFLFLGNE D+ D++ +Q   I +++NVTT++P Y  +  LF YKRL A
Sbjct: 317 DIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKRLPA 376

Query: 301 TDCNKQDMRAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTI 480
           TD NKQ++R Y+ EA +FI+EA+     +L+HC AGVSRSATIV AYL+KHT++ +    
Sbjct: 377 TDSNKQNLRRYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAY 436

Query: 481 TFLQSKRPIVEPNFNFLGQLERYYCDLERGVESR 582
            F++ KRPI+ PN NF+GQL  +  DL  GV  R
Sbjct: 437 KFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPR 470

>sp|Q05923|DUS2_HUMAN Dual specificity protein phosphatase 2 (Dual specificity protein
           phosphatase PAC-1)
          Length = 314

 Score =  115 bits (288), Expect = 2e-25
 Identities = 57/133 (42%), Positives = 89/133 (66%)
 Frame = +1

Query: 151 EILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVPFYREDLFIYKRLSATDCNKQDMRA 330
           EILP+LFLG+   S+D++ LQ   IT +LNV+ + P + E LF YK +   D    ++ A
Sbjct: 175 EILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISA 234

Query: 331 YYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTITFLQSKRPIV 510
           ++ EAI FID   +  G+VLVHC AG+SRSATI  AYL++  ++ + +   F++ +R ++
Sbjct: 235 WFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVI 294

Query: 511 EPNFNFLGQLERY 549
            PNF+F+GQL ++
Sbjct: 295 SPNFSFMGQLLQF 307

>sp|Q16828|DUS6_HUMAN Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
           (Dual specificity protein phosphatase PYST1)
          Length = 381

 Score =  115 bits (287), Expect = 2e-25
 Identities = 65/150 (43%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
 Frame = +1

Query: 97  SPTNESNRSTDVLNATISEILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVP--FYRE 270
           SP + S  S  V      EILPFL+LG   DS +++VL+E  I +ILNVT N+P  F   
Sbjct: 197 SPLSNSQPSFPV------EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENA 250

Query: 271 DLFIYKRLSATDCNKQDMRAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLK 450
             F YK++  +D   Q++  ++ EAI FIDEA  +N  VLVHC AG+SRS T+  AYL++
Sbjct: 251 GEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQ 310

Query: 451 HTKLNVLQTITFLQSKRPIVEPNFNFLGQL 540
              L++      ++ K+  + PNFNF+GQL
Sbjct: 311 KLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340

>sp|Q64346|DUS6_RAT Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
          Length = 381

 Score =  115 bits (287), Expect = 2e-25
 Identities = 65/150 (43%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
 Frame = +1

Query: 97  SPTNESNRSTDVLNATISEILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVP--FYRE 270
           SP + S  S  V      EILPFL+LG   DS +++VL+E  I +ILNVT N+P  F   
Sbjct: 197 SPLSNSQPSFPV------EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENA 250

Query: 271 DLFIYKRLSATDCNKQDMRAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLK 450
             F YK++  +D   Q++  ++ EAI FIDEA  +N  VLVHC AG+SRS T+  AYL++
Sbjct: 251 GEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQ 310

Query: 451 HTKLNVLQTITFLQSKRPIVEPNFNFLGQL 540
              L++      ++ K+  + PNFNF+GQL
Sbjct: 311 KLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340

>sp|Q9DBB1|DUS6_MOUSE Dual specificity protein phosphatase 6 (Mitogen-activated protein
           kinase phosphatase 3) (MAP kinase phosphatase 3) (MKP-3)
          Length = 381

 Score =  115 bits (287), Expect = 2e-25
 Identities = 65/150 (43%), Positives = 92/150 (61%), Gaps = 2/150 (1%)
 Frame = +1

Query: 97  SPTNESNRSTDVLNATISEILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVP--FYRE 270
           SP + S  S  V      EILPFL+LG   DS +++VL+E  I +ILNVT N+P  F   
Sbjct: 197 SPLSNSQPSFPV------EILPFLYLGCAKDSTNLDVLEEFGIKYILNVTPNLPNLFENA 250

Query: 271 DLFIYKRLSATDCNKQDMRAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLK 450
             F YK++  +D   Q++  ++ EAI FIDEA  +N  VLVHC AG+SRS T+  AYL++
Sbjct: 251 GEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISRSVTVTVAYLMQ 310

Query: 451 HTKLNVLQTITFLQSKRPIVEPNFNFLGQL 540
              L++      ++ K+  + PNFNF+GQL
Sbjct: 311 KLNLSMNDAYDIVKMKKSNISPNFNFMGQL 340

>sp|Q05922|DUS2_MOUSE Dual specificity protein phosphatase 2 (Dual specificity protein
           phosphatase PAC-1)
          Length = 318

 Score =  115 bits (287), Expect = 2e-25
 Identities = 56/130 (43%), Positives = 87/130 (66%)
 Frame = +1

Query: 151 EILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVPFYREDLFIYKRLSATDCNKQDMRA 330
           EILP+L+LG+   S+D++ LQ   IT +LNV+ + P + E LF YK +   D    ++ A
Sbjct: 179 EILPYLYLGSCNHSSDLQGLQACGITAVLNVSASCPNHFEGLFHYKSIPVEDNQMVEISA 238

Query: 331 YYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTITFLQSKRPIV 510
           ++ EAI FID   +  G+VLVHC AG+SRSATI  AYL++  ++ + +   F++ +R ++
Sbjct: 239 WFQEAISFIDSVKNSGGRVLVHCQAGISRSATICLAYLIQSHRVRLDEAFDFVKQRRGVI 298

Query: 511 EPNFNFLGQL 540
            PNF+F+GQL
Sbjct: 299 SPNFSFMGQL 308

>sp|P28562|DUS1_HUMAN Dual specificity protein phosphatase 1 (MAP kinase phosphatase 1)
           (MKP-1) (Protein-tyrosine phosphatase CL100) (Dual
           specificity protein phosphatase hVH1)
          Length = 367

 Score =  113 bits (283), Expect = 7e-25
 Identities = 56/147 (38%), Positives = 92/147 (62%), Gaps = 7/147 (4%)
 Frame = +1

Query: 151 EILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVPFYREDLFIYKRLSATDCNKQDMRA 330
           EILPFL+LG+   ++  ++L    IT ++NV+ N P + E  + YK +   D +K D+ +
Sbjct: 176 EILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISS 235

Query: 331 YYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTITFLQSKRPIV 510
           +++EAI FID   +  G+V VHC AG+SRSATI  AYL++  ++ + +   F++ +R I+
Sbjct: 236 WFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSII 295

Query: 511 EPNFNFLGQLERY-------YCDLERG 570
            PNF+F+GQL ++       +C  E G
Sbjct: 296 SPNFSFMGQLLQFESQVLAPHCSAEAG 322

>sp|Q99956|DUS9_HUMAN Dual specificity protein phosphatase 9 (Mitogen-activated protein
           kinase phosphatase 4) (MAP kinase phosphatase 4) (MKP-4)
          Length = 384

 Score =  113 bits (282), Expect = 9e-25
 Identities = 67/156 (42%), Positives = 96/156 (61%), Gaps = 5/156 (3%)
 Frame = +1

Query: 151 EILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVP--FYREDLFIYKRLSATDCNKQDM 324
           +ILP L+LG+  DS ++E L +  I +ILNVT N+P  F +   F YK++  +D   Q++
Sbjct: 206 QILPNLYLGSARDSANLESLAKLGIRYILNVTPNLPNFFEKNGDFHYKQIPISDHWSQNL 265

Query: 325 RAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTITFLQSKRP 504
             ++ EAI+FIDEA SQN  VLVHC AGVSRS T+  AYL++   L++      ++ K+ 
Sbjct: 266 SRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVTVAYLMQKLHLSLNDAYDLVKRKKS 325

Query: 505 IVEPNFNFLGQLERYYCDLERGV---ESRSKEFAFG 603
            + PNFNF+GQL     D ER +   E  S+E   G
Sbjct: 326 NISPNFNFMGQL----LDFERSLRLEERHSQEQGSG 357

>sp|Q16829|DUS7_HUMAN Dual specificity protein phosphatase 7 (Dual specificity protein
           phosphatase PYST2)
          Length = 368

 Score =  111 bits (278), Expect = 3e-24
 Identities = 58/132 (43%), Positives = 86/132 (65%), Gaps = 2/132 (1%)
 Frame = +1

Query: 151 EILPFLFLGNEMDSNDVEVLQEKKITHILNVTTNVP--FYREDLFIYKRLSATDCNKQDM 324
           +ILP+L+LG   DS +++VL +  I +ILNVT N+P  F     F YK++  +D   Q++
Sbjct: 196 QILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNL 255

Query: 325 RAYYHEAIQFIDEAYSQNGKVLVHCWAGVSRSATIVAAYLLKHTKLNVLQTITFLQSKRP 504
             ++ EAI FIDEA S+   VLVHC AG+SRS T+  AYL++   L++     F++ K+ 
Sbjct: 256 SQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKS 315

Query: 505 IVEPNFNFLGQL 540
            + PNFNF+GQL
Sbjct: 316 NISPNFNFMGQL 327

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,842,437
Number of Sequences: 369166
Number of extensions: 1819333
Number of successful extensions: 4434
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4259
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4405
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9654860130
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00490

  1. Dr_sW_013_B01
  2. Dr_sW_016_G06