DrC_00487
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00487 (615 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase... 222 5e-58 sp|P60051|UBP14_PANTR Ubiquitin carboxyl-terminal hydrolase... 222 5e-58 sp|Q9JMA1|UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase... 220 3e-57 sp|P40826|UBP14_RABIT Ubiquitin carboxyl-terminal hydrolase... 220 3e-57 sp|Q17361|UBP14_CAEEL Ubiquitin carboxyl-terminal hydrolase... 156 3e-38 sp|Q92353|UBP6_SCHPO Probable ubiquitin carboxyl-terminal h... 122 6e-28 sp|P43593|UBP6_YEAST Ubiquitin carboxyl-terminal hydrolase ... 96 1e-19 sp|P39967|UBP9_YEAST Ubiquitin carboxyl-terminal hydrolase ... 58 2e-08 sp|P53874|UBP10_YEAST Ubiquitin carboxyl-terminal hydrolase... 54 3e-07 sp|Q70EK9|UBP51_HUMAN Ubiquitin carboxyl-terminal hydrolase... 53 7e-07
>sp|P54578|UBP14_HUMAN Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 494 Score = 222 bits (566), Expect = 5e-58 Identities = 102/172 (59%), Positives = 130/172 (75%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 PAYL++Q VRF+YKEKE +NAKVLKD+KF ++LDMYE CT EL+ KM R K+K +ED+ Sbjct: 321 PAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDK 380 Query: 182 KAEAERINKKGENLIDNTKLEESKPEHYPYWFSDDIGSNNCGIYELQAIVTHQGRSSSSG 361 K + N D + + ++ P+ F+DDIGSNNCG Y+LQA++THQGRSSSSG Sbjct: 381 KVNQQ------PNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSG 434 Query: 362 HYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYVLLYGPKSIE 517 HYV WV++ D W+K+DDD V+ VT EDILRLSGGGDWH AYVLLYGP+ +E Sbjct: 435 HYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 486
>sp|P60051|UBP14_PANTR Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 222 bits (566), Expect = 5e-58 Identities = 102/172 (59%), Positives = 130/172 (75%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 PAYL++Q VRF+YKEKE +NAKVLKD+KF ++LDMYE CT EL+ KM R K+K +ED+ Sbjct: 321 PAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDMYELCTPELQEKMVSFRSKFKDLEDK 380 Query: 182 KAEAERINKKGENLIDNTKLEESKPEHYPYWFSDDIGSNNCGIYELQAIVTHQGRSSSSG 361 K + N D + + ++ P+ F+DDIGSNNCG Y+LQA++THQGRSSSSG Sbjct: 381 KVNQQ------PNTSDKKSSPQKEVKYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSG 434 Query: 362 HYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYVLLYGPKSIE 517 HYV WV++ D W+K+DDD V+ VT EDILRLSGGGDWH AYVLLYGP+ +E Sbjct: 435 HYVSWVKRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 486
>sp|Q9JMA1|UBP14_MOUSE Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 220 bits (560), Expect = 3e-57 Identities = 105/172 (61%), Positives = 133/172 (77%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 PAYL++Q VRF+YKEKE +NAKVLKD+KF ++LD+YE CT EL+ KM R K+K +ED+ Sbjct: 321 PAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDLEDK 380 Query: 182 KAEAERINKKGENLIDNTKLEESKPEHYPYWFSDDIGSNNCGIYELQAIVTHQGRSSSSG 361 K +N++ N+ +E K E P+ F+DDIGSNNCG Y+LQA++THQGRSSSSG Sbjct: 381 K-----VNQQPNANDKNSPPKEIKYE--PFSFADDIGSNNCGYYDLQAVLTHQGRSSSSG 433 Query: 362 HYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYVLLYGPKSIE 517 HYV WVR+ D W+K+DDD V+ VT EDILRLSGGGDWH AYVLLYGP+ +E Sbjct: 434 HYVSWVRRKQDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 485
>sp|P40826|UBP14_RABIT Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 493 Score = 220 bits (560), Expect = 3e-57 Identities = 101/172 (58%), Positives = 129/172 (75%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 PAYL++Q VRF+YKEKE +NAKVLKD+KF ++LD+YE CT EL+ KM R K+K +ED+ Sbjct: 320 PAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDVYELCTPELQEKMVSFRSKFKDIEDK 379 Query: 182 KAEAERINKKGENLIDNTKLEESKPEHYPYWFSDDIGSNNCGIYELQAIVTHQGRSSSSG 361 K + N D + + + P+ F+DDIGSNNCG Y+LQA++THQGRSSSSG Sbjct: 380 KVNQQ------PNASDKKSSPQKEVRYEPFSFADDIGSNNCGYYDLQAVLTHQGRSSSSG 433 Query: 362 HYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYVLLYGPKSIE 517 HYV WV++ D W+K+DDD V+ VT EDILRLSGGGDWH AYVLLYGP+ +E Sbjct: 434 HYVSWVKRKHDEWIKFDDDKVSIVTPEDILRLSGGGDWHIAYVLLYGPRRVE 485
>sp|Q17361|UBP14_CAEEL Ubiquitin carboxyl-terminal hydrolase 14 (Ubiquitin thiolesterase 14) (Ubiquitin-specific processing protease 14) (Deubiquitinating enzyme 14) Length = 489 Score = 156 bits (395), Expect = 3e-38 Identities = 82/179 (45%), Positives = 108/179 (60%), Gaps = 6/179 (3%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 P YL+V RF+YKE + NAK+LK ++F + LD Y+ C+ ELK K+ R K+ ED Sbjct: 291 PKYLTVNINRFFYKESTKTNAKILKSVQFPMQLDTYDLCSQELKDKLVARRADIKLEEDA 350 Query: 182 KAEAERINK-----KGENLIDNTKLEESKPEHYPYWFSDDIGSNNCGIYELQAIVTHQGR 346 K E E K +G+ + D+ P F DD GSNN G Y+L+ I+TH+GR Sbjct: 351 KLERELRKKVLDKEQGDKIFDDGVA-------LPTAFEDDAGSNNSGFYDLKGIITHKGR 403 Query: 347 SSSSGHYVGWVRQSGD-IWLKYDDDSVTQVTAEDILRLSGGGDWHCAYVLLYGPKSIEK 520 SS GHYV W+R S D W +DD+ VT V E IL+ SGGGDWH AYVLLY + I++ Sbjct: 404 SSQDGHYVAWMRSSEDGKWRLFDDEHVTVVDEEAILKTSGGGDWHSAYVLLYEARVIKQ 462
>sp|Q92353|UBP6_SCHPO Probable ubiquitin carboxyl-terminal hydrolase 6 (Ubiquitin thiolesterase 6) (Ubiquitin-specific processing protease 6) (Deubiquitinating enzyme 6) Length = 467 Score = 122 bits (307), Expect = 6e-28 Identities = 72/190 (37%), Positives = 101/190 (53%), Gaps = 19/190 (10%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 P YL+V FVRFY+K AK+L+ +KF LD EFCT EL K+ P+RDK + +E Sbjct: 284 PNYLTVNFVRFYWKASIGKKAKILRKVKFPFELDAVEFCTPELSQKLIPVRDKLREIEKN 343 Query: 182 KAEAERINKKGENLIDNTKLEESKPEH-----------------YPYWFSDDIGSNNCGI 310 E ER K+ K++ S+ E +DD G+N G+ Sbjct: 344 DEEHERAAKR-------IKIQPSEDEKEAEAECRLTQVATCQSLVDPELADDEGANPTGL 396 Query: 311 YELQAIVTHQGRSSSSGHYVGWVRQSGD--IWLKYDDDSVTQVTAEDILRLSGGGDWHCA 484 Y+L +++H G S+SSGHY W+R S + W +++D V+ V AE I L GGG+ A Sbjct: 397 YDLVGVLSHAGASASSGHYQAWIRNSNNRAEWFRFNDAKVSIVPAEKIETLDGGGEADSA 456 Query: 485 YVLLYGPKSI 514 Y+LLY K I Sbjct: 457 YILLYKAKDI 466
>sp|P43593|UBP6_YEAST Ubiquitin carboxyl-terminal hydrolase 6 (Ubiquitin thiolesterase 6) (Ubiquitin-specific processing protease 6) (Deubiquitinating enzyme 6) Length = 499 Score = 95.5 bits (236), Expect = 1e-19 Identities = 61/188 (32%), Positives = 97/188 (51%), Gaps = 22/188 (11%) Frame = +2 Query: 2 PAYLSVQFVRFYYKEKERINAKVLKDIKFSIVLDMYEFCTDELKSKMQPMRDKYKIMEDR 181 P +L+VQ+VRF++K +K+L+ + F LD+ + T E ++ +RD+ + +E Sbjct: 307 PKFLTVQYVRFFWKRSTNKKSKILRKVVFPFQLDVADMLTPEYAAEKVKVRDELRKVEKE 366 Query: 182 KAEAERINKK-------GENLI-------DNTKLEESKP----EHYPYWFSDDI--GSNN 301 K E ER K+ EN++ L ES+ E Y F ++ G N Sbjct: 367 KNEKEREIKRRKFDPSSSENVMTpreQYETQVALNESEKDQWLEEYKKHFPPNLEKGENP 426 Query: 302 CGIYELQAIVTHQGRSSSSGHYVGWVRQSGD--IWLKYDDDSVTQVTAEDILRLSGGGDW 475 +Y L ++THQG +S SGHY ++R D W K++DD V+ V E I L+GGG+ Sbjct: 427 SCVYNLIGVITHQGANSESGHYQAFIRDELDENKWYKFNDDKVSVVEKEKIESLAGGGES 486 Query: 476 HCAYVLLY 499 A +L+Y Sbjct: 487 DSALILMY 494
>sp|P39967|UBP9_YEAST Ubiquitin carboxyl-terminal hydrolase 9 (Ubiquitin thiolesterase 9) (Ubiquitin-specific processing protease 9) (Deubiquitinating enzyme 9) Length = 754 Score = 58.2 bits (139), Expect = 2e-08 Identities = 35/99 (35%), Positives = 45/99 (45%), Gaps = 1/99 (1%) Frame = +2 Query: 311 YELQAIVTHQGRSSSSGHYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSG-GGDWHCAY 487 YEL +V H G GHYV R WL YDD++V + E +L+ +G GD AY Sbjct: 601 YELSGVVIHMGSGPQHGHYVCICRNEKFGWLLYDDETVESIKEETVLQFTGHPGDQTTAY 660 Query: 488 VLLYGPKSIEKDAYKNNGDQAVSQQMGYELNM*KFLINC 604 VL Y +K +N SQ N + LI C Sbjct: 661 VLFYKETQADKTENQNENIDTSSQDQMQTDNNIEQLIKC 699
>sp|P53874|UBP10_YEAST Ubiquitin carboxyl-terminal hydrolase 10 (Ubiquitin thiolesterase 10) (Ubiquitin-specific processing protease 10) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) Length = 792 Score = 53.9 bits (128), Expect = 3e-07 Identities = 36/110 (32%), Positives = 52/110 (47%), Gaps = 9/110 (8%) Frame = +2 Query: 311 YELQAIVTHQGRSSSSGHYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYV 490 Y+L ++V H+GRS SSGHY+ +Q W YDD+ + ++ D+L+ AY Sbjct: 674 YQLLSVVVHEGRSLSSGHYIAHCKQPDGSWATYDDEYINIISERDVLKEPN------AYY 727 Query: 491 LLY---GPKSIEKDAYK------NNGDQAVSQQMGYELNM*KFLINCSKN 613 LLY PKS+ K N ++ +Q E N IN KN Sbjct: 728 LLYTRLTPKSVPLPLAKSAMATGNVTSKSKQEQAVNEPNNRPLKINSKKN 777
>sp|Q70EK9|UBP51_HUMAN Ubiquitin carboxyl-terminal hydrolase 51 (Ubiquitin thiolesterase 51) (Ubiquitin-specific processing protease 51) (Deubiquitinating enzyme 51) Length = 711 Score = 52.8 bits (125), Expect = 7e-07 Identities = 27/71 (38%), Positives = 38/71 (53%) Frame = +2 Query: 311 YELQAIVTHQGRSSSSGHYVGWVRQSGDIWLKYDDDSVTQVTAEDILRLSGGGDWHCAYV 490 Y L A++ H G + SGHY ++RQ D W DD +T+ T ED+L G Y+ Sbjct: 649 YSLFAVINHHG-TLESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEG-------YL 700 Query: 491 LLYGPKSIEKD 523 L Y + +EKD Sbjct: 701 LFYHKQGLEKD 711
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 65,910,265
Number of Sequences: 369166
Number of extensions: 1301151
Number of successful extensions: 3852
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3711
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3827
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
