Planaria EST Database

DrC_00483

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00483
         (872 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q24307|IAP2_DROME  Apoptosis 2 inhibitor (Inhibitor of ap...    66   1e-10
sp|P98170|BIRC4_HUMAN  Baculoviral IAP repeat-containing pro...    65   2e-10
sp|Q86YT6|MIB1_HUMAN  Ubiquitin ligase protein MIB1 (Mind bo...    64   4e-10
sp|Q13489|BIRC3_HUMAN  Baculoviral IAP repeat-containing pro...    64   5e-10
sp|Q13490|BIRC2_HUMAN  Baculoviral IAP repeat-containing pro...    62   2e-09
sp|Q6GNY1|MIB1_XENLA  Ubiquitin ligase protein MIB1 (Mind bo...    62   2e-09
sp|Q80SY4|MIB1_MOUSE  Ubiquitin ligase protein MIB1 (Mind bo...    62   2e-09
sp|O62640|PIAP_PIG  Putative inhibitor of apoptosis                62   2e-09
sp|Q90660|BIR_CHICK  Inhibitor of apoptosis protein (IAP) (I...    62   2e-09
sp|Q9R0I6|BIRC4_RAT  Baculoviral IAP repeat-containing prote...    62   2e-09

>sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP)
           (IAP homolog A) (IAP-like protein) (DILP)
          Length = 498

 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 29/57 (50%), Positives = 41/57 (71%)
 Frame = +1

Query: 313 SVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIE 483
           S++E+N QL+       C VCLD++V VVFLPCGHL TCN C+  +++CP+CR  I+
Sbjct: 437 SLEEENRQLK---DARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIK 490

>sp|P98170|BIRC4_HUMAN Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
           protein 3) (X-linked inhibitor of apoptosis protein)
           (X-linked IAP) (IAP-like protein) (HILP)
          Length = 497

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 12/91 (13%)
 Frame = +1

Query: 244 TGKDYDSTHEFLSDLKNYREIKHSVQEDNYQ------------LEFIFPNNYCVVCLDKQ 387
           +G +Y S    ++DL N +  K S+Q+++ Q            L  +     C +C+D+ 
Sbjct: 400 SGSNYKSLEVLVADLVNAQ--KDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRN 457

Query: 388 VAVVFLPCGHLKTCNDCSNLLSSCPVCRTVI 480
           +A+VF+PCGHL TC  C+  +  CP+C TVI
Sbjct: 458 IAIVFVPCGHLVTCKQCAEAVDKCPMCYTVI 488

>sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
           (DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ
           type with ankyrin repeat domain protein 2)
          Length = 1006

 Score = 64.3 bits (155), Expect = 4e-10
 Identities = 25/43 (58%), Positives = 32/43 (74%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 492
           CVVC DK+ AV+F PCGH+  C +C+NL+  C  CR V+ERRV
Sbjct: 866 CVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVVERRV 908


 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 28/68 (41%), Positives = 39/68 (57%)
 Frame = +1

Query: 289  KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVC 468
            K+   +   VQ+   QL+ I     C VCLD+   ++FL CGH  TC  C + +S CP+C
Sbjct: 938  KDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPIC 995

Query: 469  RTVIERRV 492
            R  IERR+
Sbjct: 996  RKAIERRI 1003


 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 489
           C+VC D +   +F PCGH+ TC+ CS  +  C +C+  ++ R
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSR 860

>sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
           protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF
           signaling complex protein 1) (IAP homolog C) (Apoptosis
           inhibitor 2) (API2)
          Length = 604

 Score = 63.9 bits (154), Expect = 5e-10
 Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 6/71 (8%)
 Frame = +1

Query: 298 REIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSC 459
           ++IK+   ED        QL  +     C VC+DK+V++VF+PCGHL  C DC+  L  C
Sbjct: 529 QDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKC 588

Query: 460 PVCRTVIERRV 492
           P+CR+ I+  V
Sbjct: 589 PICRSTIKGTV 599

>sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
           protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF
           signaling complex protein 2) (IAP homolog B)
          Length = 618

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 25/53 (47%), Positives = 35/53 (66%)
 Frame = +1

Query: 334 QLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 492
           QL  +     C VC+DK+V+VVF+PCGHL  C +C+  L  CP+CR +I+  V
Sbjct: 561 QLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTV 613

>sp|Q6GNY1|MIB1_XENLA Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
          Length = 1011

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 24/43 (55%), Positives = 32/43 (74%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 492
           CVVC DK+ AV+F PCGH+  C +C++L+  C  CR V+ERRV
Sbjct: 867 CVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRV 909


 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 27/68 (39%), Positives = 39/68 (57%)
 Frame = +1

Query: 289  KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVC 468
            K+   +   VQ+   QL+ I     C VCLD+   ++F+ CGH  TC  C + +S CP+C
Sbjct: 939  KDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFM-CGH-GTCQLCGDRMSECPIC 996

Query: 469  RTVIERRV 492
            R  IERR+
Sbjct: 997  RKAIERRI 1004


 Score = 43.1 bits (100), Expect = 0.001
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 489
           C+VC D +   +F PCGH+ TC+ CS  +  C +C+  ++ R
Sbjct: 820 CMVCSDLKRDTLFGPCGHIATCSLCSPRVKKCLLCKEQVQSR 861

>sp|Q80SY4|MIB1_MOUSE Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
           (DAPK-interacting protein 1) (DIP-1)
          Length = 1006

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 24/43 (55%), Positives = 32/43 (74%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 492
           CVVC DK+ AV+F PCGH+  C +C++L+  C  CR V+ERRV
Sbjct: 866 CVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRV 908


 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 28/68 (41%), Positives = 39/68 (57%)
 Frame = +1

Query: 289  KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVC 468
            K+   +   VQ+   QL+ I     C VCLD+   ++FL CGH  TC  C + +S CP+C
Sbjct: 938  KDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPIC 995

Query: 469  RTVIERRV 492
            R  IERR+
Sbjct: 996  RKAIERRI 1003


 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 16/42 (38%), Positives = 26/42 (61%)
 Frame = +1

Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 489
           C+VC D +   +F PCGH+ TC+ CS  +  C +C+  ++ R
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSR 860

>sp|O62640|PIAP_PIG Putative inhibitor of apoptosis
          Length = 358

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 25/53 (47%), Positives = 34/53 (64%)
 Frame = +1

Query: 334 QLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 492
           QL  +     C VC+DK+V++VF+PCGHL  C DC+  L  CP+CR  I+  V
Sbjct: 301 QLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTV 353

>sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis
           protein)
          Length = 611

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
 Frame = +1

Query: 250 KDYDSTHEFLSDLKNYREIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPC 411
           KD+D       DL   + +K+   ED        QL  +     C VC+DK+V++VF+PC
Sbjct: 522 KDFDPV--LYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPC 579

Query: 412 GHLKTCNDCSNLLSSCPVCRTVIERRV 492
           GHL  C +C+  L  CP+CR  I+  V
Sbjct: 580 GHLVVCKECAPSLRKCPICRGTIKGTV 606

>sp|Q9R0I6|BIRC4_RAT Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
           protein 3) (X-linked inhibitor of apoptosis protein)
           (X-linked IAP) (IAP homolog A) (RIAP3) (RIAP-3)
          Length = 496

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 30/89 (33%), Positives = 50/89 (56%), Gaps = 10/89 (11%)
 Frame = +1

Query: 244 TGKDYDSTHEFLSDLKNYRE-------IKHSVQED---NYQLEFIFPNNYCVVCLDKQVA 393
           +G +Y S    ++DL + ++        + S+Q+D     QL  +     C +C+D+ +A
Sbjct: 399 SGSNYLSLEVLIADLVSAQKDNSQDESSQTSLQKDISTEEQLRRLQEEKLCKICMDRNIA 458

Query: 394 VVFLPCGHLKTCNDCSNLLSSCPVCRTVI 480
           +VF+PCGHL TC  C+  +  CP+C TVI
Sbjct: 459 IVFVPCGHLVTCKQCAEAVDKCPMCCTVI 487

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,463,022
Number of Sequences: 369166
Number of extensions: 1890928
Number of successful extensions: 5402
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5181
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5372
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00483

  1. Dr_sW_008_M10
  2. Dr_sW_012_N08