Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_M10
(422 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of ap... 66 3e-11
sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bo... 64 1e-10
sp|P98170|BIRC4_HUMAN Baculoviral IAP repeat-containing pro... 64 1e-10
sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing pro... 64 1e-10
sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing pro... 62 4e-10
sp|Q6GNY1|MIB1_XENLA Ubiquitin ligase protein MIB1 (Mind bo... 62 4e-10
sp|Q80SY4|MIB1_MOUSE Ubiquitin ligase protein MIB1 (Mind bo... 62 4e-10
sp|O62640|PIAP_PIG Putative inhibitor of apoptosis 62 4e-10
sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (I... 62 4e-10
sp|O08863|BIRC3_MOUSE Baculoviral IAP repeat-containing pro... 62 6e-10
>sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP)
(IAP homolog A) (IAP-like protein) (DILP)
Length = 498
Score = 66.2 bits (160), Expect = 3e-11
Identities = 29/57 (50%), Positives = 41/57 (71%)
Frame = +3
Query: 126 SVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIE 296
S++E+N QL+ C VCLD++V VVFLPCGHL TCN C+ +++CP+CR I+
Sbjct: 437 SLEEENRQLK---DARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMCRADIK 490
>sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
(DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ
type with ankyrin repeat domain protein 2)
Length = 1006
Score = 64.3 bits (155), Expect = 1e-10
Identities = 25/43 (58%), Positives = 32/43 (74%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
CVVC DK+ AV+F PCGH+ C +C+NL+ C CR V+ERRV
Sbjct: 866 CVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVVERRV 908
Score = 53.9 bits (128), Expect = 1e-07
Identities = 27/63 (42%), Positives = 37/63 (58%)
Frame = +3
Query: 117 IKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIE 296
+ VQ+ QL+ I C VCLD+ ++FL CGH TC C + +S CP+CR IE
Sbjct: 943 VNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPICRKAIE 1000
Query: 297 RRV 305
RR+
Sbjct: 1001 RRI 1003
Score = 44.3 bits (103), Expect = 1e-04
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 302
C+VC D + +F PCGH+ TC+ CS + C +C+ ++ R
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSR 860
>sp|P98170|BIRC4_HUMAN Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
protein 3) (X-linked inhibitor of apoptosis protein)
(X-linked IAP) (IAP-like protein) (HILP)
Length = 497
Score = 63.9 bits (154), Expect = 1e-10
Identities = 31/91 (34%), Positives = 50/91 (54%), Gaps = 12/91 (13%)
Frame = +3
Query: 57 TGKDYDSTYEFLSDLNNYREIKHSVQEDNYQ------------LEFIFPNNYCVVCLDKQ 200
+G +Y S ++DL N + K S+Q+++ Q L + C +C+D+
Sbjct: 400 SGSNYKSLEVLVADLVNAQ--KDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRN 457
Query: 201 VAVVFLPCGHLKTCNDCSNLLSSCPVCRTVI 293
+A+VF+PCGHL TC C+ + CP+C TVI
Sbjct: 458 IAIVFVPCGHLVTCKQCAEAVDKCPMCYTVI 488
>sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF
signaling complex protein 1) (IAP homolog C) (Apoptosis
inhibitor 2) (API2)
Length = 604
Score = 63.9 bits (154), Expect = 1e-10
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 6/71 (8%)
Frame = +3
Query: 111 REIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSC 272
++IK+ ED QL + C VC+DK+V++VF+PCGHL C DC+ L C
Sbjct: 529 QDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKC 588
Query: 273 PVCRTVIERRV 305
P+CR+ I+ V
Sbjct: 589 PICRSTIKGTV 599
>sp|Q13490|BIRC2_HUMAN Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis
protein 2) (HIAP2) (HIAP-2) (C-IAP1) (TNFR2-TRAF
signaling complex protein 2) (IAP homolog B)
Length = 618
Score = 62.4 bits (150), Expect = 4e-10
Identities = 25/53 (47%), Positives = 35/53 (66%)
Frame = +3
Query: 147 QLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
QL + C VC+DK+V+VVF+PCGHL C +C+ L CP+CR +I+ V
Sbjct: 561 QLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTV 613
>sp|Q6GNY1|MIB1_XENLA Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
Length = 1011
Score = 62.4 bits (150), Expect = 4e-10
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
CVVC DK+ AV+F PCGH+ C +C++L+ C CR V+ERRV
Sbjct: 867 CVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRV 909
Score = 53.1 bits (126), Expect = 2e-07
Identities = 26/63 (41%), Positives = 37/63 (58%)
Frame = +3
Query: 117 IKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIE 296
+ VQ+ QL+ I C VCLD+ ++F+ CGH TC C + +S CP+CR IE
Sbjct: 944 VNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFM-CGH-GTCQLCGDRMSECPICRKAIE 1001
Query: 297 RRV 305
RR+
Sbjct: 1002 RRI 1004
Score = 43.1 bits (100), Expect = 2e-04
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 302
C+VC D + +F PCGH+ TC+ CS + C +C+ ++ R
Sbjct: 820 CMVCSDLKRDTLFGPCGHIATCSLCSPRVKKCLLCKEQVQSR 861
>sp|Q80SY4|MIB1_MOUSE Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
(DAPK-interacting protein 1) (DIP-1)
Length = 1006
Score = 62.4 bits (150), Expect = 4e-10
Identities = 24/43 (55%), Positives = 32/43 (74%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
CVVC DK+ AV+F PCGH+ C +C++L+ C CR V+ERRV
Sbjct: 866 CVVCSDKKAAVLFQPCGHMCACENCASLMKKCVQCRAVVERRV 908
Score = 53.9 bits (128), Expect = 1e-07
Identities = 27/63 (42%), Positives = 37/63 (58%)
Frame = +3
Query: 117 IKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIE 296
+ VQ+ QL+ I C VCLD+ ++FL CGH TC C + +S CP+CR IE
Sbjct: 943 VNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPICRKAIE 1000
Query: 297 RRV 305
RR+
Sbjct: 1001 RRI 1003
Score = 44.3 bits (103), Expect = 1e-04
Identities = 16/42 (38%), Positives = 26/42 (61%)
Frame = +3
Query: 177 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERR 302
C+VC D + +F PCGH+ TC+ CS + C +C+ ++ R
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSR 860
>sp|O62640|PIAP_PIG Putative inhibitor of apoptosis
Length = 358
Score = 62.4 bits (150), Expect = 4e-10
Identities = 25/53 (47%), Positives = 34/53 (64%)
Frame = +3
Query: 147 QLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
QL + C VC+DK+V++VF+PCGHL C DC+ L CP+CR I+ V
Sbjct: 301 QLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTV 353
>sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis
protein)
Length = 611
Score = 62.4 bits (150), Expect = 4e-10
Identities = 32/87 (36%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
Frame = +3
Query: 63 KDYDSTYEFLSDLNNYREIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPC 224
KD+D DL + +K+ ED QL + C VC+DK+V++VF+PC
Sbjct: 522 KDFDPV--LYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPC 579
Query: 225 GHLKTCNDCSNLLSSCPVCRTVIERRV 305
GHL C +C+ L CP+CR I+ V
Sbjct: 580 GHLVVCKECAPSLRKCPICRGTIKGTV 606
>sp|O08863|BIRC3_MOUSE Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
protein 1) (MIAP1) (MIAP-1)
Length = 600
Score = 61.6 bits (148), Expect = 6e-10
Identities = 24/53 (45%), Positives = 34/53 (64%)
Frame = +3
Query: 147 QLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCRTVIERRV 305
QL + C VC+D++V++VF+PCGHL C DC+ L CP+CR I+ V
Sbjct: 543 QLRKLQEERMCKVCMDREVSIVFIPCGHLVVCKDCAPSLRKCPICRGTIKGTV 595
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,649,036
Number of Sequences: 369166
Number of extensions: 772728
Number of successful extensions: 2702
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2625
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2679
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)