Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_N08
(872 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P98170|BIRC4_HUMAN Baculoviral IAP repeat-containing pro... 66 1e-10
sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of ap... 64 7e-10
sp|Q9R0I6|BIRC4_RAT Baculoviral IAP repeat-containing prote... 63 9e-10
sp|Q60989|BIRC4_MOUSE Baculoviral IAP repeat-containing pro... 63 1e-09
sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bo... 62 3e-09
sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing pro... 61 4e-09
sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (I... 61 5e-09
sp|Q96P09|BIRC8_HUMAN Baculoviral IAP repeat-containing pro... 60 8e-09
sp|Q95M71|BIRC8_GORGO Baculoviral IAP repeat-containing pro... 60 8e-09
sp|Q95M72|BIRC8_PANTR Baculoviral IAP repeat-containing pro... 60 8e-09
>sp|P98170|BIRC4_HUMAN Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
protein 3) (X-linked inhibitor of apoptosis protein)
(X-linked IAP) (IAP-like protein) (HILP)
Length = 497
Score = 65.9 bits (159), Expect = 1e-10
Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 12/91 (13%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDLKNYREIKHSVQEDNYQ------------LEFIFPNNYCVVCLDKQ 387
+G +Y S+ ++DL N + K S+Q+++ Q L + C +C+D+
Sbjct: 400 SGSNYKSLEVLVADLVNAQ--KDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRN 457
Query: 388 VAVVFLPCGHLKTCNDCSNLLSSCPVCGTVI 480
+A+VF+PCGHL TC C+ + CP+C TVI
Sbjct: 458 IAIVFVPCGHLVTCKQCAEAVDKCPMCYTVI 488
>sp|Q24307|IAP2_DROME Apoptosis 2 inhibitor (Inhibitor of apoptosis 2) (dIAP2) (DIAP)
(IAP homolog A) (IAP-like protein) (DILP)
Length = 498
Score = 63.5 bits (153), Expect = 7e-10
Identities = 27/52 (51%), Positives = 38/52 (73%)
Frame = +1
Query: 313 SVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVC 468
S++E+N QL+ C VCLD++V VVFLPCGHL TCN C+ +++CP+C
Sbjct: 437 SLEEENRQLK---DARLCKVCLDEEVGVVFLPCGHLATCNQCAPSVANCPMC 485
>sp|Q9R0I6|BIRC4_RAT Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
protein 3) (X-linked inhibitor of apoptosis protein)
(X-linked IAP) (IAP homolog A) (RIAP3) (RIAP-3)
Length = 496
Score = 63.2 bits (152), Expect = 9e-10
Identities = 30/89 (33%), Positives = 51/89 (57%), Gaps = 10/89 (11%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDLKNYRE-------IKHSVQED---NYQLEFIFPNNYCVVCLDKQVA 393
+G +Y S+ ++DL + ++ + S+Q+D QL + C +C+D+ +A
Sbjct: 399 SGSNYLSLEVLIADLVSAQKDNSQDESSQTSLQKDISTEEQLRRLQEEKLCKICMDRNIA 458
Query: 394 VVFLPCGHLKTCNDCSNLLSSCPVCGTVI 480
+VF+PCGHL TC C+ + CP+C TVI
Sbjct: 459 IVFVPCGHLVTCKQCAEAVDKCPMCCTVI 487
>sp|Q60989|BIRC4_MOUSE Baculoviral IAP repeat-containing protein 4 (Inhibitor of apoptosis
protein 3) (X-linked inhibitor of apoptosis protein)
(X-linked IAP) (IAP homolog A) (MIAP3) (MIAP-3)
Length = 496
Score = 62.8 bits (151), Expect = 1e-09
Identities = 30/89 (33%), Positives = 50/89 (56%), Gaps = 10/89 (11%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDLKNYRE-------IKHSVQED---NYQLEFIFPNNYCVVCLDKQVA 393
+G Y S+ ++DL + ++ + S+Q+D QL + C +C+D+ +A
Sbjct: 399 SGSSYLSLEVLIADLVSAQKDNTEDESSQTSLQKDISTEEQLRRLQEEKLCKICMDRNIA 458
Query: 394 VVFLPCGHLKTCNDCSNLLSSCPVCGTVI 480
+VF+PCGHL TC C+ + CP+C TVI
Sbjct: 459 IVFVPCGHLVTCKQCAEAVDKCPMCYTVI 487
>sp|Q86YT6|MIB1_HUMAN Ubiquitin ligase protein MIB1 (Mind bomb homolog 1)
(DAPK-interacting protein 1) (DIP-1) (Zinc finger ZZ
type with ankyrin repeat domain protein 2)
Length = 1006
Score = 61.6 bits (148), Expect = 3e-09
Identities = 24/43 (55%), Positives = 31/43 (72%)
Frame = +1
Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCGTVIERRV 492
CVVC DK+ AV+F PCGH+ C +C+NL+ C C V+ERRV
Sbjct: 866 CVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVVERRV 908
Score = 52.4 bits (124), Expect = 2e-06
Identities = 27/68 (39%), Positives = 38/68 (55%)
Frame = +1
Query: 289 KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVC 468
K+ + VQ+ QL+ I C VCLD+ ++FL CGH TC C + +S CP+C
Sbjct: 938 KDNTNVNADVQKLQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPIC 995
Query: 469 GTVIERRV 492
IERR+
Sbjct: 996 RKAIERRI 1003
Score = 42.7 bits (99), Expect = 0.001
Identities = 16/42 (38%), Positives = 25/42 (59%)
Frame = +1
Query: 364 CVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSCPVCGTVIERR 489
C+VC D + +F PCGH+ TC+ CS + C +C ++ R
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICKEQVQSR 860
>sp|Q13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Inhibitor of apoptosis
protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF
signaling complex protein 1) (IAP homolog C) (Apoptosis
inhibitor 2) (API2)
Length = 604
Score = 61.2 bits (147), Expect = 4e-09
Identities = 28/71 (39%), Positives = 41/71 (57%), Gaps = 6/71 (8%)
Frame = +1
Query: 298 REIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPCGHLKTCNDCSNLLSSC 459
++IK+ ED QL + C VC+DK+V++VF+PCGHL C DC+ L C
Sbjct: 529 QDIKYIPTEDVSDLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKC 588
Query: 460 PVCGTVIERRV 492
P+C + I+ V
Sbjct: 589 PICRSTIKGTV 599
>sp|Q90660|BIR_CHICK Inhibitor of apoptosis protein (IAP) (Inhibitor of T cell apoptosis
protein)
Length = 611
Score = 60.8 bits (146), Expect = 5e-09
Identities = 31/83 (37%), Positives = 46/83 (55%), Gaps = 7/83 (8%)
Frame = +1
Query: 250 KDYDSIHEFLSDLKNYREIKHSVQED------NYQLEFIFPNNYCVVCLDKQVAVVFLPC 411
KD+D + DL + +K+ ED QL + C VC+DK+V++VF+PC
Sbjct: 522 KDFDPV--LYKDLFVEKSMKYVPTEDVSGLPMEEQLRRLQEERTCKVCMDKEVSIVFIPC 579
Query: 412 GHLKTCNDCSNLLSSCPVC-GTV 477
GHL C +C+ L CP+C GT+
Sbjct: 580 GHLVVCKECAPSLRKCPICRGTI 602
>sp|Q96P09|BIRC8_HUMAN Baculoviral IAP repeat-containing protein 8 (Inhibitor of
apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
(Testis-specific inhibitor of apoptosis)
Length = 236
Score = 60.1 bits (144), Expect = 8e-09
Identities = 26/90 (28%), Positives = 50/90 (55%), Gaps = 10/90 (11%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDLKNYRE--IKHSVQEDNYQLEF--------IFPNNYCVVCLDKQVA 393
+G +Y ++ ++DL + ++ ++ + + + Q E + C +C+D+ +A
Sbjct: 139 SGSNYKTLEVLVADLVSAQKDTTENELNQTSLQREISPEEPLRRLQEEKLCKICMDRYIA 198
Query: 394 VVFLPCGHLKTCNDCSNLLSSCPVCGTVIE 483
VVF+PCGHL TC C+ + CP+C VI+
Sbjct: 199 VVFIPCGHLVTCKQCAEAVDRCPMCSAVID 228
>sp|Q95M71|BIRC8_GORGO Baculoviral IAP repeat-containing protein 8 (Inhibitor of
apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
Length = 236
Score = 60.1 bits (144), Expect = 8e-09
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDL-----------KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQV 390
+G +Y ++ ++DL N ++ + + L + C +C+D+ +
Sbjct: 139 SGSNYKTLEVLVADLVSAQKDTTENESNQTSLQREISPEE-PLRRLQEEKLCKICMDRHI 197
Query: 391 AVVFLPCGHLKTCNDCSNLLSSCPVCGTVIE 483
AVVF+PCGHL TC C+ + CP+C VI+
Sbjct: 198 AVVFIPCGHLVTCKQCAEAVDRCPMCNAVID 228
>sp|Q95M72|BIRC8_PANTR Baculoviral IAP repeat-containing protein 8 (Inhibitor of
apoptosis-like protein 2) (IAP-like protein 2) (ILP-2)
Length = 236
Score = 60.1 bits (144), Expect = 8e-09
Identities = 26/91 (28%), Positives = 46/91 (50%), Gaps = 11/91 (12%)
Frame = +1
Query: 244 TGKDYDSIHEFLSDL-----------KNYREIKHSVQEDNYQLEFIFPNNYCVVCLDKQV 390
+G +Y ++ ++DL N ++ + + L + C +C+D+ +
Sbjct: 139 SGSNYKTLEVLVADLVSAQKDTTENESNQTSLQREISPEE-PLRRLQDEKLCKICMDRHI 197
Query: 391 AVVFLPCGHLKTCNDCSNLLSSCPVCGTVIE 483
AVVF+PCGHL TC C+ + CP+C VI+
Sbjct: 198 AVVFIPCGHLVTCKQCAEAVDRCPMCSAVID 228
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,352,016
Number of Sequences: 369166
Number of extensions: 1839187
Number of successful extensions: 5778
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5525
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5764
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8646143400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)