Planaria EST Database

DrC_00480

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00480
         (960 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q63524|TMED2_RAT  Transmembrane emp24 domain trafficking ...   189   1e-47
sp|Q15363|TMED2_HUMAN  Transmembrane emp24 domain traffickin...   189   1e-47
sp|P49020|TMED2_CRIGR  Transmembrane emp24 domain traffickin...   189   1e-47
sp|Q9R0Q3|TMED2_MOUSE  Transmembrane emp24 domain traffickin...   189   1e-47
sp|O17528|SEL9_CAEEL  Suppressor/enhancer of lin-12 protein ...   183   5e-46
sp|Q9Y3B3|TMED7_HUMAN  Transmembrane emp24 domain containing...   115   2e-25
sp|Q78IS1|TMED3_MOUSE  Transmembrane emp24 domain containing...   104   4e-22
sp|Q6AY25|TMED3_RAT  Transmembrane emp24 domain containing p...   102   2e-21
sp|Q9Y3Q3|TMED3_HUMAN  Transmembrane emp24 domain containing...   100   6e-21
sp|Q9CXE7|TMED5_MOUSE  Transmembrane emp24 domain containing...    91   4e-18

>sp|Q63524|TMED2_RAT Transmembrane emp24 domain trafficking protein 2 precursor
           (Membrane protein p24A) (RNP21.4)
          Length = 201

 Score =  189 bits (479), Expect = 1e-47
 Identities = 92/165 (55%), Positives = 121/165 (73%), Gaps = 3/165 (1%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           + EECFF+R+   T M L++EVAEGG LDID +IT P    +Y   ++S  K+TF    D
Sbjct: 28  HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 87

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPK--KVSSDSH-TKLEEMVNDLDKALTTVKHE 429
           G YK+CFSN MS++T KI+MF++D    PK   + +++H  KLEEM+N+L  A+T VKHE
Sbjct: 88  GTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHE 147

Query: 430 QEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
           QEYME RE+IHR IN+NTNSRV+LW+ FEA VLV M+ GQ+YYLK
Sbjct: 148 QEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLK 192

>sp|Q15363|TMED2_HUMAN Transmembrane emp24 domain trafficking protein 2 precursor
           (Membrane protein p24A)
          Length = 201

 Score =  189 bits (479), Expect = 1e-47
 Identities = 92/165 (55%), Positives = 121/165 (73%), Gaps = 3/165 (1%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           + EECFF+R+   T M L++EVAEGG LDID +IT P    +Y   ++S  K+TF    D
Sbjct: 28  HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 87

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPK--KVSSDSH-TKLEEMVNDLDKALTTVKHE 429
           G YK+CFSN MS++T KI+MF++D    PK   + +++H  KLEEM+N+L  A+T VKHE
Sbjct: 88  GTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHE 147

Query: 430 QEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
           QEYME RE+IHR IN+NTNSRV+LW+ FEA VLV M+ GQ+YYLK
Sbjct: 148 QEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLK 192

>sp|P49020|TMED2_CRIGR Transmembrane emp24 domain trafficking protein 2 precursor
           (COPI-coated vesicle membrane protein p24)
          Length = 196

 Score =  189 bits (479), Expect = 1e-47
 Identities = 92/165 (55%), Positives = 121/165 (73%), Gaps = 3/165 (1%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           + EECFF+R+   T M L++EVAEGG LDID +IT P    +Y   ++S  K+TF    D
Sbjct: 23  HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 82

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPK--KVSSDSH-TKLEEMVNDLDKALTTVKHE 429
           G YK+CFSN MS++T KI+MF++D    PK   + +++H  KLEEM+N+L  A+T VKHE
Sbjct: 83  GTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHE 142

Query: 430 QEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
           QEYME RE+IHR IN+NTNSRV+LW+ FEA VLV M+ GQ+YYLK
Sbjct: 143 QEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLK 187

>sp|Q9R0Q3|TMED2_MOUSE Transmembrane emp24 domain trafficking protein 2 precursor
           (Membrane protein p24A) (Sid 394)
          Length = 201

 Score =  189 bits (479), Expect = 1e-47
 Identities = 92/165 (55%), Positives = 121/165 (73%), Gaps = 3/165 (1%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           + EECFF+R+   T M L++EVAEGG LDID +IT P    +Y   ++S  K+TF    D
Sbjct: 28  HAEECFFERVTSGTKMGLIFEVAEGGFLDIDVEITGPDNKGIYKGDRESSGKYTFAAHMD 87

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPK--KVSSDSH-TKLEEMVNDLDKALTTVKHE 429
           G YK+CFSN MS++T KI+MF++D    PK   + +++H  KLEEM+N+L  A+T VKHE
Sbjct: 88  GTYKFCFSNRMSTMTPKIVMFTIDIGEAPKGQDMETEAHQNKLEEMINELAVAMTAVKHE 147

Query: 430 QEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
           QEYME RE+IHR IN+NTNSRV+LW+ FEA VLV M+ GQ+YYLK
Sbjct: 148 QEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYLK 192

>sp|O17528|SEL9_CAEEL Suppressor/enhancer of lin-12 protein 9 precursor
          Length = 203

 Score =  183 bits (465), Expect = 5e-46
 Identities = 89/169 (52%), Positives = 116/169 (68%), Gaps = 7/169 (4%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           N E+CFFDR+   T M L++EVAEGG LDID KIT P    +Y   ++S  KFTF    D
Sbjct: 26  NEEQCFFDRLTSGTKMGLMFEVAEGGFLDIDVKITGPDNKEIYKGERESSGKFTFAAHMD 85

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPKKV-------SSDSHTKLEEMVNDLDKALTT 417
           G+Y YCF N MS++T K +MF+++   P ++         +  + KLEEMV +L  AL +
Sbjct: 86  GVYTYCFGNKMSTMTPKAVMFTVEITEPHQQAPGAAANQDAADNAKLEEMVRELSSALMS 145

Query: 418 VKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
           VKHEQEYME RE++HR INENTNSRV++WA FEA VLV M+ GQ++YLK
Sbjct: 146 VKHEQEYMEVRERVHRNINENTNSRVVMWAAFEAFVLVGMTVGQIFYLK 194

>sp|Q9Y3B3|TMED7_HUMAN Transmembrane emp24 domain containing protein 7 precursor
          Length = 224

 Score =  115 bits (288), Expect = 2e-25
 Identities = 60/166 (36%), Positives = 91/166 (54%), Gaps = 4/166 (2%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           N ++CF++ I   T   L ++V  GG  D+D ++ DP G VLY  +KK  D FTF    +
Sbjct: 44  NAKQCFYEDIAQGTKCTLEFQVITGGHYDVDCRLEDPDGKVLYKEMKKQYDSFTFTASKN 103

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPKKVSSDSH----TKLEEMVNDLDKALTTVKH 426
           G YK+CFSN  S+ T+K + F       P    S++     T++E     + +AL +V  
Sbjct: 104 GTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHEALKSVID 163

Query: 427 EQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
            Q +   RE   R   E+ N+RV  W++ EA +L+V+S GQV+ LK
Sbjct: 164 YQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLK 209

>sp|Q78IS1|TMED3_MOUSE Transmembrane emp24 domain containing protein 3 precursor
          Length = 221

 Score =  104 bits (259), Expect = 4e-22
 Identities = 56/167 (33%), Positives = 86/167 (51%), Gaps = 5/167 (2%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           N ++CF + ++      L Y+V  GG  D+D  + DP G V+Y   KK  D FT++T+A 
Sbjct: 40  NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPRGNVIYRETKKQYDSFTYKTEAK 99

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPKKVSSDSH-----TKLEEMVNDLDKALTTVK 423
           G+Y++CFSN  S+ ++K + F       P  +    +     T++E     + +AL TV 
Sbjct: 100 GVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVI 159

Query: 424 HEQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
             Q +   RE   R   E+ NSRV  W++ E   L V+S  QV  LK
Sbjct: 160 DSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLK 206

>sp|Q6AY25|TMED3_RAT Transmembrane emp24 domain containing protein 3 precursor
          Length = 221

 Score =  102 bits (254), Expect = 2e-21
 Identities = 54/167 (32%), Positives = 85/167 (50%), Gaps = 5/167 (2%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           N ++CF + ++      L Y+V  GG  D+D  + DP G ++Y   KK  D FT++T+  
Sbjct: 40  NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPMGNIIYRETKKQYDSFTYKTEVK 99

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPKKVSSDSH-----TKLEEMVNDLDKALTTVK 423
           G+Y++CFSN  S+ ++K + F       P  +    +     T++E     + +AL TV 
Sbjct: 100 GVYRFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVI 159

Query: 424 HEQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
             Q +   RE   R   E+ NSRV  W++ E   L V+S  QV  LK
Sbjct: 160 DSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLK 206

>sp|Q9Y3Q3|TMED3_HUMAN Transmembrane emp24 domain containing protein 3 precursor (Membrane
           protein p24B)
          Length = 217

 Score =  100 bits (249), Expect = 6e-21
 Identities = 54/167 (32%), Positives = 83/167 (49%), Gaps = 5/167 (2%)
 Frame = +1

Query: 79  NVEECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKAD 258
           N ++CF + ++      L Y+V  GG  D+D  + DP G  +Y   KK  D FT+R +  
Sbjct: 36  NAKQCFHEEVEQGVKFSLDYQVITGGHYDVDCYVEDPQGNTIYRETKKQYDSFTYRAEVK 95

Query: 259 GIYKYCFSNTMSSVTNKILMFSLDTVSPPKKVSSDSH-----TKLEEMVNDLDKALTTVK 423
           G+Y++CFSN  S+ ++K + F       P  +    +     T++E     + +AL TV 
Sbjct: 96  GVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIHEALKTVI 155

Query: 424 HEQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
             Q +   RE   R   E+ NSRV  W++ E   L V+S  QV  LK
Sbjct: 156 DSQTHYRLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLLK 202

>sp|Q9CXE7|TMED5_MOUSE Transmembrane emp24 domain containing protein 5 precursor
          Length = 229

 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 57/175 (32%), Positives = 85/175 (48%), Gaps = 15/175 (8%)
 Frame = +1

Query: 85  EECFFDRIKPDTDMLLLYEVAEGGSLDIDAKITDPSGAVLYSAVKKSDDKFTFRTKADGI 264
           +ECF+  +     + + Y+V +GG LDID  +T P G  L    +KSD   T  T+ DG 
Sbjct: 45  KECFYQPMPLKASLEIEYQVLDGGELDIDFHLTSPEGRTLVFEQRKSDGVHTIETE-DGD 103

Query: 265 YKYCFSNTMSSVTNKILMFSLDTVSPPKKVSSDS------------HTKLE---EMVNDL 399
           Y +CF NT S+++ K++ F L   +  ++V                  KLE   E +N +
Sbjct: 104 YMFCFDNTFSTISEKVIFFELILDNMGEEVQGQEDWKKYITNTDVLEMKLEDILESINSI 163

Query: 400 DKALTTVKHEQEYMETREKIHRKINENTNSRVLLWAIFEACVLVVMSAGQVYYLK 564
              L+   H Q  +   E   R I E+   RV  W++    V+VV+SA QVY LK
Sbjct: 164 KSRLSKSGHIQTLLRAFEARDRNIQESNFDRVNFWSVVNLMVMVVVSAIQVYTLK 218

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,892,333
Number of Sequences: 369166
Number of extensions: 1754422
Number of successful extensions: 4468
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4303
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4436
length of database: 68,354,980
effective HSP length: 111
effective length of database: 47,849,395
effective search space used: 9952674160
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00480

  1. Dr_sW_012_L24
  2. Dr_sW_028_L15
  3. Dr_sW_009_F12