Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00460 (882 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (Epsin... 128 2e-29 sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (Epsin... 128 2e-29 sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3) 101 2e-21 sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3) 101 3e-21 sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1)... 98 3e-20 sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1) 98 3e-20 sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1)... 98 3e-20 sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2)... 97 8e-20 sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2) 97 8e-20 sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2) 96 1e-19
>sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin interacting protein localized in the trans-Golgi region) (Clint) Length = 625 Score = 128 bits (322), Expect = 2e-29 Identities = 58/103 (56%), Positives = 73/103 (70%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E+KVR ATNDDPWGP GQ M EIA+ T Y+ ++M MLW RM ++ K NWRR YK Sbjct: 25 ESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLL 84 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 RNGS+R+V S +EH+YDLR LE+Y ++DE GKDQG+N Sbjct: 85 LLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGIN 127
Score = 39.3 bits (90), Expect = 0.015 Identities = 19/48 (39%), Positives = 29/48 (60%) Frame = +2 Query: 734 VRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRYCD 877 +R K KE+ +++ +L ERKK+ N++KY G S SV G RY + Sbjct: 128 IRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRYSE 174
>sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin) Length = 631 Score = 128 bits (322), Expect = 2e-29 Identities = 58/103 (56%), Positives = 73/103 (70%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E+KVR ATNDDPWGP GQ M EIA+ T Y+ ++M MLW RM ++ K NWRR YK Sbjct: 33 ESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLL 92 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 RNGS+R+V S +EH+YDLR LE+Y ++DE GKDQG+N Sbjct: 93 LLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGIN 135
Score = 38.9 bits (89), Expect = 0.019 Identities = 19/46 (41%), Positives = 28/46 (60%) Frame = +2 Query: 734 VRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRY 871 +R K KE+ +++ +L ERKK+ N++KY G S SV G RY Sbjct: 136 IRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRY 180
>sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3) Length = 636 Score = 101 bits (252), Expect = 2e-21 Identities = 48/103 (46%), Positives = 65/103 (63%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + A+VMGM+WRR+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGK-NWRHVYKALT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ C+E++Y ++ L+ +QYID GKDQGVN Sbjct: 80 LLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVN 122
>sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3) Length = 632 Score = 101 bits (251), Expect = 3e-21 Identities = 48/103 (46%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +VMGMLWRR+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGK-NWRHVYKALT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ C+E++Y ++ L+ +QYID GKDQGVN Sbjct: 80 LLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVN 122
>sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1) (EH domain-binding mitotic phosphoprotein) Length = 551 Score = 98.2 bits (243), Expect = 3e-20 Identities = 44/103 (42%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN Sbjct: 80 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 122
>sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1) Length = 575 Score = 98.2 bits (243), Expect = 3e-20 Identities = 44/103 (42%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN Sbjct: 80 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 122
>sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1) (Intersectin-EH binding protein 1) (Ibp1) Length = 566 Score = 98.2 bits (243), Expect = 3e-20 Identities = 44/103 (42%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 12 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 70 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN Sbjct: 71 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 113
>sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2) (Intersectin-EH binding protein 2) (Ibp2) Length = 595 Score = 96.7 bits (239), Expect = 8e-20 Identities = 42/103 (40%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGK-NWRHVYKALT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ C+E+++ ++ L+ +QYID GKDQG+N Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
>sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2) Length = 642 Score = 96.7 bits (239), Expect = 8e-20 Identities = 42/103 (40%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGK-NWRHVYKALT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ C+E+++ ++ L+ +QYID GKDQG+N Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
>sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2) Length = 583 Score = 96.3 bits (238), Expect = 1e-19 Identities = 42/103 (40%), Positives = 64/103 (62%) Frame = +3 Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194 E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGK-NWRHVYKALT 79 Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323 + GS+R+ C+E+++ ++ L+ +QYID GKDQG+N Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 97,569,062 Number of Sequences: 369166 Number of extensions: 1891638 Number of successful extensions: 4114 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3968 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4104 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 8790245790 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)