Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_D15
(882 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (Epsin... 128 2e-29
sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (Epsin... 128 2e-29
sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3) 101 2e-21
sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3) 101 3e-21
sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1)... 98 3e-20
sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1) 98 3e-20
sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1)... 98 3e-20
sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2)... 97 8e-20
sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2) 97 8e-20
sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2) 96 1e-19
>sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin
interacting protein localized in the trans-Golgi region)
(Clint)
Length = 625
Score = 128 bits (322), Expect = 2e-29
Identities = 58/103 (56%), Positives = 73/103 (70%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E+KVR ATNDDPWGP GQ M EIA+ T Y+ ++M MLW RM ++ K NWRR YK
Sbjct: 25 ESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLL 84
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
RNGS+R+V S +EH+YDLR LE+Y ++DE GKDQG+N
Sbjct: 85 LLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGIN 127
Score = 39.3 bits (90), Expect = 0.015
Identities = 19/48 (39%), Positives = 29/48 (60%)
Frame = +2
Query: 734 VRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRYCD 877
+R K KE+ +++ +L ERKK+ N++KY G S SV G RY +
Sbjct: 128 IRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRYSE 174
>sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin)
Length = 631
Score = 128 bits (322), Expect = 2e-29
Identities = 58/103 (56%), Positives = 73/103 (70%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E+KVR ATNDDPWGP GQ M EIA+ T Y+ ++M MLW RM ++ K NWRR YK
Sbjct: 33 ESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVYKSLL 92
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
RNGS+R+V S +EH+YDLR LE+Y ++DE GKDQG+N
Sbjct: 93 LLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGIN 135
Score = 38.9 bits (89), Expect = 0.019
Identities = 19/46 (41%), Positives = 28/46 (60%)
Frame = +2
Query: 734 VRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRY 871
+R K KE+ +++ +L ERKK+ N++KY G S SV G RY
Sbjct: 136 IRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRY 180
>sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3)
Length = 636
Score = 101 bits (252), Expect = 2e-21
Identities = 48/103 (46%), Positives = 65/103 (63%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + A+VMGM+WRR+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGK-NWRHVYKALT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ C+E++Y ++ L+ +QYID GKDQGVN
Sbjct: 80 LLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVN 122
>sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3)
Length = 632
Score = 101 bits (251), Expect = 3e-21
Identities = 48/103 (46%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +VMGMLWRR+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGK-NWRHVYKALT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ C+E++Y ++ L+ +QYID GKDQGVN
Sbjct: 80 LLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVN 122
>sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1) (EH domain-binding mitotic
phosphoprotein)
Length = 551
Score = 98.2 bits (243), Expect = 3e-20
Identities = 44/103 (42%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN
Sbjct: 80 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 122
>sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1)
Length = 575
Score = 98.2 bits (243), Expect = 3e-20
Identities = 44/103 (42%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN
Sbjct: 80 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 122
>sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1) (Intersectin-EH binding
protein 1) (Ibp1)
Length = 566
Score = 98.2 bits (243), Expect = 3e-20
Identities = 44/103 (42%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 12 EIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLNDHGK-NWRHVYKAMT 70
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ CKE++Y ++ L+ +QY+D GKDQGVN
Sbjct: 71 LMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVN 113
>sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2) (Intersectin-EH binding
protein 2) (Ibp2)
Length = 595
Score = 96.7 bits (239), Expect = 8e-20
Identities = 42/103 (40%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGK-NWRHVYKALT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ C+E+++ ++ L+ +QYID GKDQG+N
Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
>sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2)
Length = 642
Score = 96.7 bits (239), Expect = 8e-20
Identities = 42/103 (40%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVWKRLNDHGK-NWRHVYKALT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ C+E+++ ++ L+ +QYID GKDQG+N
Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
>sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2)
Length = 583
Score = 96.3 bits (238), Expect = 1e-19
Identities = 42/103 (40%), Positives = 64/103 (62%)
Frame = +3
Query: 15 EAKVRAATNDDPWGPHGQDMQEIAEYTKHYDTLAQVMGMLWRRMFQEQKCNWRRTYKXXX 194
E KVR AT++DPWGP M EIA+ T + +++M M+W+R+ K NWR YK
Sbjct: 21 EIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVWKRLNDHGK-NWRHVYKALT 79
Query: 195 XXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKDQGVN 323
+ GS+R+ C+E+++ ++ L+ +QYID GKDQG+N
Sbjct: 80 LLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGIN 122
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,569,062
Number of Sequences: 369166
Number of extensions: 1891638
Number of successful extensions: 4114
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3968
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4104
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8790245790
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)