Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_P08
(347 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (Epsin... 118 4e-27
sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (Epsin... 117 6e-27
sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3) 88 5e-18
sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3) 87 2e-17
sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1)... 86 3e-17
sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1) 86 3e-17
sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1)... 86 3e-17
sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2) 84 1e-16
sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2)... 83 2e-16
sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2) 83 2e-16
>sp|Q14677|EPN4_HUMAN Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin) (Clathrin
interacting protein localized in the trans-Golgi region)
(Clint)
Length = 625
Score = 118 bits (296), Expect = 4e-27
Identities = 56/115 (48%), Positives = 75/115 (65%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
LW RM ++ K NWRR YK RNGS+R+V S +EH+YDLR LE+Y ++DE GKD
Sbjct: 64 LWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKD 123
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRYCDDDD 347
QG+NIR K KE+ +++ +L ERKK+ N++KY G S SV G RY + D
Sbjct: 124 QGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRYSERYD 177
>sp|Q99KN9|EPN4_MOUSE Epsin-4 (Epsin-related protein) (EpsinR) (Enthoprotin)
Length = 631
Score = 117 bits (294), Expect = 6e-27
Identities = 55/110 (50%), Positives = 73/110 (66%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
LW RM ++ K NWRR YK RNGS+R+V S +EH+YDLR LE+Y ++DE GKD
Sbjct: 72 LWSRMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKD 131
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSSVNGHRY 332
QG+NIR K KE+ +++ +L ERKK+ N++KY G S SV G RY
Sbjct: 132 QGINIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVS-SDSVGGFRY 180
>sp|Q9H201|EPN3_HUMAN Epsin-3 (EPS-15 interacting protein 3)
Length = 632
Score = 88.2 bits (217), Expect = 5e-18
Identities = 46/117 (39%), Positives = 68/117 (58%), Gaps = 4/117 (3%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
LWRR+ K NWR YK + GS+R+ C+E++Y ++ L+ +QYID GKD
Sbjct: 60 LWRRLNDSGK-NWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNK--YQGGGISSSVNG--HRYCDD 341
QGVN+R K K++ ALL++E +L ER + + + +G GI S G RY +D
Sbjct: 119 QGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIGIGSGQLGFSRRYGED 175
>sp|Q91W69|EPN3_MOUSE Epsin-3 (EPS-15 interacting protein 3)
Length = 636
Score = 86.7 bits (213), Expect = 2e-17
Identities = 42/110 (38%), Positives = 65/110 (59%), Gaps = 2/110 (1%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+WRR+ K NWR YK + GS+R+ C+E++Y ++ L+ +QYID GKD
Sbjct: 60 VWRRLNDSGK-NWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNK--YQGGGISSSVNGH 326
QGVN+R K K++ ALL++E +L ER + + + +G GI S G+
Sbjct: 119 QGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMGIGSGQLGY 168
>sp|Q9Y6I3|EPN1_HUMAN Epsin-1 (EPS-15 interacting protein 1) (EH domain-binding mitotic
phosphoprotein)
Length = 551
Score = 85.9 bits (211), Expect = 3e-17
Identities = 40/104 (38%), Positives = 61/104 (58%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ CKE++Y ++ L+ +QY+D GKD
Sbjct: 60 IWKRLNDHGK-NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSS 314
QGVN+R KAK++ ALL +E +L ER + + K +SS
Sbjct: 119 QGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASS 162
>sp|O88339|EPN1_RAT Epsin-1 (EPS-15 interacting protein 1)
Length = 575
Score = 85.9 bits (211), Expect = 3e-17
Identities = 40/104 (38%), Positives = 61/104 (58%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ CKE++Y ++ L+ +QY+D GKD
Sbjct: 60 IWKRLNDHGK-NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSS 314
QGVN+R KAK++ ALL +E +L ER + + K +SS
Sbjct: 119 QGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASS 162
>sp|Q80VP1|EPN1_MOUSE Epsin-1 (EPS-15 interacting protein 1) (Intersectin-EH binding
protein 1) (Ibp1)
Length = 566
Score = 85.9 bits (211), Expect = 3e-17
Identities = 40/104 (38%), Positives = 61/104 (58%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ CKE++Y ++ L+ +QY+D GKD
Sbjct: 51 IWKRLNDHGK-NWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKD 109
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNKYQGGGISSS 314
QGVN+R KAK++ ALL +E +L ER + + K +SS
Sbjct: 110 QGVNVREKAKQLVALLRDEDRLREERAHALKTKEKLAQTATASS 153
>sp|O95208|EPN2_HUMAN Epsin-2 (EPS-15 interacting protein 2)
Length = 642
Score = 83.6 bits (205), Expect = 1e-16
Identities = 34/95 (35%), Positives = 60/95 (63%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ C+E+++ ++ L+ +QYID GKD
Sbjct: 60 VWKRLNDHGK-NWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNK 287
QG+N+R K+K++ ALL++E +L ER ++ + +
Sbjct: 119 QGINVREKSKQLVALLKDEERLKAERAQALKTKER 153
>sp|Q8CHU3|EPN2_MOUSE Epsin-2 (EPS-15 interacting protein 2) (Intersectin-EH binding
protein 2) (Ibp2)
Length = 595
Score = 83.2 bits (204), Expect = 2e-16
Identities = 34/95 (35%), Positives = 60/95 (63%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ C+E+++ ++ L+ +QYID GKD
Sbjct: 60 VWKRLNDHGK-NWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNK 287
QG+N+R K+K++ ALL++E +L ER ++ + +
Sbjct: 119 QGINVREKSKQLVALLKDEERLKVERVQALKTKER 153
>sp|Q9Z1Z3|EPN2_RAT Epsin-2 (EPS-15 interacting protein 2)
Length = 583
Score = 83.2 bits (204), Expect = 2e-16
Identities = 34/95 (35%), Positives = 60/95 (63%)
Frame = +3
Query: 3 LWRRMFQEQKCNWRRTYKXXXXXXXXXRNGSDRIVMSCKEHVYDLRLLESYQYIDETGKD 182
+W+R+ K NWR YK + GS+R+ C+E+++ ++ L+ +QYID GKD
Sbjct: 60 VWKRLNDHGK-NWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKD 118
Query: 183 QGVNIRHKAKEITALLENESQLSTERKKSAMNRNK 287
QG+N+R K+K++ ALL++E +L ER ++ + +
Sbjct: 119 QGINVREKSKQLVALLKDEERLKVERVQALKTKER 153
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,369,028
Number of Sequences: 369166
Number of extensions: 777549
Number of successful extensions: 2013
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1970
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2010
length of database: 68,354,980
effective HSP length: 83
effective length of database: 53,021,975
effective search space used: 1696703200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)