Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00457 (725 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9CQ88|SAS_MOUSE Sarcoma amplified sequence homolog 123 6e-28 sp|Q7ZUB3|SAS_BRARE Sarcoma amplified sequence homolog 121 2e-27 sp|Q7ZWW7|SAS2_XENLA Sarcoma amplified sequence homolog 2 119 8e-27 sp|Q5U1V9|SAS_RAT Sarcoma amplified sequence homolog 119 8e-27 sp|Q5FVL6|TSN13_RAT Tetraspanin-13 (Tspan-13) (Transmembran... 118 2e-26 sp|Q5RAP8|SAS_PONPY Sarcoma amplified sequence homolog 117 4e-26 sp|O95857|TSN13_HUMAN Tetraspanin-13 (Tspan-13) (Transmembr... 115 9e-26 sp|Q9D8C2|TSN13_MOUSE Tetraspanin-13 (Tspan-13) (Transmembr... 115 9e-26 sp|Q12999|SAS_HUMAN Sarcoma amplified sequence (Tetraspanin... 114 2e-25 sp|Q5XHG6|SAS1_XENLA Sarcoma amplified sequence homolog 1 113 5e-25
>sp|Q9CQ88|SAS_MOUSE Sarcoma amplified sequence homolog Length = 210 Score = 123 bits (308), Expect = 6e-28 Identities = 72/219 (32%), Positives = 112/219 (51%), Gaps = 1/219 (0%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LV FLLI A+ + +V+ VFL ++A G+ + H Sbjct: 11 NALCALNVVYMLVGFLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAANH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357 +QV QF I+C CLA+N + +++ W S+ + + ++F+CC Sbjct: 71 HQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWSVLSNSTRHELERSFDCC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537 GL NLT + ++T C + + + CQ C + +KA Sbjct: 131 GLF---------------NLTTLR--LQDDTSC--SAVCKTKSSTCQMCGERFLKHSDKA 171 Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 +K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL Sbjct: 172 LKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q7ZUB3|SAS_BRARE Sarcoma amplified sequence homolog Length = 212 Score = 121 bits (303), Expect = 2e-27 Identities = 73/219 (33%), Positives = 116/219 (52%), Gaps = 1/219 (0%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L +LN++Y+LV LLI+ A+ + IV+ FL ++A +G+ H Sbjct: 11 NALCSLNVVYMLVGLLLIVVAAWGKGFGIVSSIHIIGGVIAVGFFLQLIAIVGLIGAVHH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWK-NSDHAQIIVMKTFNCC 357 +QV QF ++C CLA+N +E L+ WK S+ +I + K +CC Sbjct: 71 HQVMLFFYMVILFVVFLFQFGVSCSCLAMNQGQQEKLLESSWKIMSNDTRISLEKKLDCC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537 GL N + L+ + + + CT ++ ++C KMLQ+S ++A Sbjct: 131 GLF-----NSTNLQADIMS----------DLHLCTSPCTQKKECVTCGL-KMLQHS-SEA 173 Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 +K+ G VGL FSFTEI+GVWLA+R+RN +DP A+P FL Sbjct: 174 LKILGGVGLFFSFTEILGVWLAMRYRNQKDPRANPSAFL 212
>sp|Q7ZWW7|SAS2_XENLA Sarcoma amplified sequence homolog 2 Length = 212 Score = 119 bits (298), Expect = 8e-27 Identities = 72/219 (32%), Positives = 109/219 (49%), Gaps = 1/219 (0%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LV LLI+ A+ + IV+ VFL ++A +G+ H Sbjct: 11 NALCALNVVYMLVGVLLIIVAAWGKGFGIVSSIHIIGGVIAIGVFLLLIAIIGLIGAVSH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357 +QV QF ++C CLA+N +E L+ W S+ ++ + KT +CC Sbjct: 71 HQVMLFIYMVVLILVFIFQFIVSCSCLAMNRSQQEYLLNTTWNRMSNETRLNLEKTLDCC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537 G + + + E K +A C V S CP C + ++A Sbjct: 131 GFLNTT-EGRDEFKQDVA--------------LCIQVCSDPHKCP--SCGDKMLNHADEA 173 Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 +K+ G VGL FSFTEI+GVWLA R+RN +DP A+P FL Sbjct: 174 LKILGGVGLFFSFTEILGVWLAFRYRNQKDPRANPSAFL 212
>sp|Q5U1V9|SAS_RAT Sarcoma amplified sequence homolog Length = 210 Score = 119 bits (298), Expect = 8e-27 Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 3/221 (1%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LV LLI A+ + +V+ VFL ++A G+ H Sbjct: 11 NALCALNVVYMLVGLLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW---KNSDHAQIIVMKTFN 351 +QV QF I+C CLA+N + +++ W NS ++ ++F+ Sbjct: 71 HQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWWVLSNSTRHEL--ERSFD 128 Query: 352 CCGLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLN 531 CCGL NLT ++ C+ + + PCQ C + + Sbjct: 129 CCGLF---------------NLTTVH---LHDDASCSA-LCKTRSSPCQMCGETFLKHSD 169 Query: 532 KAVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 KA+K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL Sbjct: 170 KALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q5FVL6|TSN13_RAT Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13) Length = 204 Score = 118 bits (295), Expect = 2e-26 Identities = 66/216 (30%), Positives = 101/216 (46%) Frame = +1 Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186 L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72 Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366 V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132 Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546 + ++ C +N C C +I Y + ++ Sbjct: 133 NYNPNDTCPASCAKSNQKCSS---------CAPIIGEY---------------AGEVLRF 168 Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 G +GL FSFTEI+GVWL R+RN +DP A+P FL Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q5RAP8|SAS_PONPY Sarcoma amplified sequence homolog Length = 210 Score = 117 bits (292), Expect = 4e-26 Identities = 76/220 (34%), Positives = 114/220 (51%), Gaps = 2/220 (0%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LVS LLI A+ + +V+ VFL ++A G+ H Sbjct: 11 NALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW-KNSDHAQIIVMKTFNCC 357 +QV QF I+C CLA+N + +++ W S+ + + ++F+CC Sbjct: 71 HQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQADVINASWWVMSNKTRDELERSFDCC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCW-KMLQYSLNK 534 GL NLT + CT I + + CQ C K L+YS ++ Sbjct: 131 GLF---------------NLTTLY---QQDYDFCTA-ICKSQSPTCQMCGEKFLKYS-DE 170 Query: 535 AVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 A+K+ G VGL FSFTEI+GVWLA+RFRN++DP A+P FL Sbjct: 171 ALKILGGVGLFFSFTEILGVWLAMRFRNLKDPRANPSAFL 210
>sp|O95857|TSN13_HUMAN Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13) (Tetraspan NET-6) Length = 204 Score = 115 bits (289), Expect = 9e-26 Identities = 65/216 (30%), Positives = 102/216 (47%) Frame = +1 Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186 L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72 Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366 V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNQEQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132 Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546 + ++ C ++ +C C +I Y + ++ Sbjct: 133 SVNPNDTCLASCVKSDHSCSP---------CAPIIGEY---------------AGEVLRF 168 Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 G +GL FSFTEI+GVWL R+RN +DP A+P FL Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q9D8C2|TSN13_MOUSE Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13) Length = 204 Score = 115 bits (289), Expect = 9e-26 Identities = 65/216 (30%), Positives = 100/216 (46%) Frame = +1 Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186 L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72 Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366 V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132 Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546 + ++ C + C C +I Y + ++ Sbjct: 133 SYNPNDTCPASCAKSTQKCSS---------CAPIIGEY---------------AGEVLRF 168 Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 G +GL FSFTEI+GVWL R+RN +DP A+P FL Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q12999|SAS_HUMAN Sarcoma amplified sequence (Tetraspanin-31) (Tspan-31) Length = 210 Score = 114 bits (286), Expect = 2e-25 Identities = 72/219 (32%), Positives = 109/219 (49%), Gaps = 1/219 (0%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LVS LLI A+ + +V+ VFL ++A G+ H Sbjct: 11 NALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW-KNSDHAQIIVMKTFNCC 357 +QV QF I+C CLA+N + +++ W S+ + + ++F+CC Sbjct: 71 HQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQTDVINASWWVMSNKTRDELERSFDCC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537 GL NLT + CT I + + CQ C + ++A Sbjct: 131 GLF---------------NLTTLY---QQDYDFCTA-ICKSQSPTCQMCGEKFLKHSDEA 171 Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 +K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL Sbjct: 172 LKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q5XHG6|SAS1_XENLA Sarcoma amplified sequence homolog 1 Length = 212 Score = 113 bits (283), Expect = 5e-25 Identities = 70/223 (31%), Positives = 106/223 (47%), Gaps = 5/223 (2%) Frame = +1 Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180 ++L ALN++Y+LV LLI A+ + IV+ VFL ++A +G+ H Sbjct: 11 NALCALNVVYMLVGLLLIGVAAWGKGFGIVSSIHIIGGVIAIGVFLLLIAIIGLIGAVSH 70 Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357 +QV QF ++C CLA+N +E + W+ S+ ++ + +T CC Sbjct: 71 HQVMLFIYMVVLILVFIFQFIVSCSCLAMNRSQQEYFLNTTWRRMSNETRLNLEETLECC 130 Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCP----CQQCWKMLQYS 525 G + N T + + C+ V CP C C + Sbjct: 131 GFL---------------NTTEARELFNKDVALCSHV------CPDPHKCLSCGDKMLNH 169 Query: 526 LNKAVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654 ++A+K+ G VGL FSFTEI+GVWLA RFRN +DP A+P FL Sbjct: 170 ADEALKILGGVGLFFSFTEILGVWLAFRFRNQKDPRANPSAFL 212
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 77,853,452 Number of Sequences: 369166 Number of extensions: 1515874 Number of successful extensions: 3158 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3039 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3145 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6510836890 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)