Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_P22
(725 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CQ88|SAS_MOUSE Sarcoma amplified sequence homolog 123 6e-28
sp|Q7ZUB3|SAS_BRARE Sarcoma amplified sequence homolog 121 2e-27
sp|Q7ZWW7|SAS2_XENLA Sarcoma amplified sequence homolog 2 119 8e-27
sp|Q5U1V9|SAS_RAT Sarcoma amplified sequence homolog 119 8e-27
sp|Q5FVL6|TSN13_RAT Tetraspanin-13 (Tspan-13) (Transmembran... 118 2e-26
sp|Q5RAP8|SAS_PONPY Sarcoma amplified sequence homolog 117 4e-26
sp|O95857|TSN13_HUMAN Tetraspanin-13 (Tspan-13) (Transmembr... 115 9e-26
sp|Q9D8C2|TSN13_MOUSE Tetraspanin-13 (Tspan-13) (Transmembr... 115 9e-26
sp|Q12999|SAS_HUMAN Sarcoma amplified sequence (Tetraspanin... 114 2e-25
sp|Q5XHG6|SAS1_XENLA Sarcoma amplified sequence homolog 1 113 5e-25
>sp|Q9CQ88|SAS_MOUSE Sarcoma amplified sequence homolog
Length = 210
Score = 123 bits (308), Expect = 6e-28
Identities = 72/219 (32%), Positives = 112/219 (51%), Gaps = 1/219 (0%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LV FLLI A+ + +V+ VFL ++A G+ + H
Sbjct: 11 NALCALNVVYMLVGFLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAANH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357
+QV QF I+C CLA+N + +++ W S+ + + ++F+CC
Sbjct: 71 HQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWSVLSNSTRHELERSFDCC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537
GL NLT + ++T C + + + CQ C + +KA
Sbjct: 131 GLF---------------NLTTLR--LQDDTSC--SAVCKTKSSTCQMCGERFLKHSDKA 171
Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
+K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL
Sbjct: 172 LKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q7ZUB3|SAS_BRARE Sarcoma amplified sequence homolog
Length = 212
Score = 121 bits (303), Expect = 2e-27
Identities = 73/219 (33%), Positives = 116/219 (52%), Gaps = 1/219 (0%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L +LN++Y+LV LLI+ A+ + IV+ FL ++A +G+ H
Sbjct: 11 NALCSLNVVYMLVGLLLIVVAAWGKGFGIVSSIHIIGGVIAVGFFLQLIAIVGLIGAVHH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWK-NSDHAQIIVMKTFNCC 357
+QV QF ++C CLA+N +E L+ WK S+ +I + K +CC
Sbjct: 71 HQVMLFFYMVILFVVFLFQFGVSCSCLAMNQGQQEKLLESSWKIMSNDTRISLEKKLDCC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537
GL N + L+ + + + CT ++ ++C KMLQ+S ++A
Sbjct: 131 GLF-----NSTNLQADIMS----------DLHLCTSPCTQKKECVTCGL-KMLQHS-SEA 173
Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
+K+ G VGL FSFTEI+GVWLA+R+RN +DP A+P FL
Sbjct: 174 LKILGGVGLFFSFTEILGVWLAMRYRNQKDPRANPSAFL 212
>sp|Q7ZWW7|SAS2_XENLA Sarcoma amplified sequence homolog 2
Length = 212
Score = 119 bits (298), Expect = 8e-27
Identities = 72/219 (32%), Positives = 109/219 (49%), Gaps = 1/219 (0%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LV LLI+ A+ + IV+ VFL ++A +G+ H
Sbjct: 11 NALCALNVVYMLVGVLLIIVAAWGKGFGIVSSIHIIGGVIAIGVFLLLIAIIGLIGAVSH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357
+QV QF ++C CLA+N +E L+ W S+ ++ + KT +CC
Sbjct: 71 HQVMLFIYMVVLILVFIFQFIVSCSCLAMNRSQQEYLLNTTWNRMSNETRLNLEKTLDCC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537
G + + + E K +A C V S CP C + ++A
Sbjct: 131 GFLNTT-EGRDEFKQDVA--------------LCIQVCSDPHKCP--SCGDKMLNHADEA 173
Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
+K+ G VGL FSFTEI+GVWLA R+RN +DP A+P FL
Sbjct: 174 LKILGGVGLFFSFTEILGVWLAFRYRNQKDPRANPSAFL 212
>sp|Q5U1V9|SAS_RAT Sarcoma amplified sequence homolog
Length = 210
Score = 119 bits (298), Expect = 8e-27
Identities = 72/221 (32%), Positives = 109/221 (49%), Gaps = 3/221 (1%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LV LLI A+ + +V+ VFL ++A G+ H
Sbjct: 11 NALCALNVVYMLVGLLLIGVAAWGKGLGVVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW---KNSDHAQIIVMKTFN 351
+QV QF I+C CLA+N + +++ W NS ++ ++F+
Sbjct: 71 HQVLLFFYMIILGLVFIFQFGISCSCLAINRNTQADVINASWWVLSNSTRHEL--ERSFD 128
Query: 352 CCGLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLN 531
CCGL NLT ++ C+ + + PCQ C + +
Sbjct: 129 CCGLF---------------NLTTVH---LHDDASCSA-LCKTRSSPCQMCGETFLKHSD 169
Query: 532 KAVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
KA+K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL
Sbjct: 170 KALKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q5FVL6|TSN13_RAT Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13)
Length = 204
Score = 118 bits (295), Expect = 2e-26
Identities = 66/216 (30%), Positives = 101/216 (46%)
Frame = +1
Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186
L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q
Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72
Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366
V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG
Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132
Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546
+ ++ C +N C C +I Y + ++
Sbjct: 133 NYNPNDTCPASCAKSNQKCSS---------CAPIIGEY---------------AGEVLRF 168
Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
G +GL FSFTEI+GVWL R+RN +DP A+P FL
Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q5RAP8|SAS_PONPY Sarcoma amplified sequence homolog
Length = 210
Score = 117 bits (292), Expect = 4e-26
Identities = 76/220 (34%), Positives = 114/220 (51%), Gaps = 2/220 (0%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LVS LLI A+ + +V+ VFL ++A G+ H
Sbjct: 11 NALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW-KNSDHAQIIVMKTFNCC 357
+QV QF I+C CLA+N + +++ W S+ + + ++F+CC
Sbjct: 71 HQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQADVINASWWVMSNKTRDELERSFDCC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCW-KMLQYSLNK 534
GL NLT + CT I + + CQ C K L+YS ++
Sbjct: 131 GLF---------------NLTTLY---QQDYDFCTA-ICKSQSPTCQMCGEKFLKYS-DE 170
Query: 535 AVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
A+K+ G VGL FSFTEI+GVWLA+RFRN++DP A+P FL
Sbjct: 171 ALKILGGVGLFFSFTEILGVWLAMRFRNLKDPRANPSAFL 210
>sp|O95857|TSN13_HUMAN Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13)
(Tetraspan NET-6)
Length = 204
Score = 115 bits (289), Expect = 9e-26
Identities = 65/216 (30%), Positives = 102/216 (47%)
Frame = +1
Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186
L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q
Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72
Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366
V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG
Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNQEQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132
Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546
+ ++ C ++ +C C +I Y + ++
Sbjct: 133 SVNPNDTCLASCVKSDHSCSP---------CAPIIGEY---------------AGEVLRF 168
Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
G +GL FSFTEI+GVWL R+RN +DP A+P FL
Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q9D8C2|TSN13_MOUSE Tetraspanin-13 (Tspan-13) (Transmembrane 4 superfamily member 13)
Length = 204
Score = 115 bits (289), Expect = 9e-26
Identities = 65/216 (30%), Positives = 100/216 (46%)
Frame = +1
Query: 7 LFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKHNQ 186
L ALN++Y LVS LLI A+ +++ +FL ++A +G+ KH+Q
Sbjct: 13 LCALNLLYTLVSLLLIGIAAWGIGFGLISSLRVVGVVIAVGIFLFLIALVGLIGAVKHHQ 72
Query: 187 VAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKNSDHAQIIVMKTFNCCGLM 366
V VQFS++C CLA+N + + L+ GW N+ A+ + + NCCG
Sbjct: 73 VLLFFYMIILLLVFIVQFSVSCACLALNREQQGQLLEVGWNNTASARNDIQRNLNCCGFR 132
Query: 367 ESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKAVKV 546
+ ++ C + C C +I Y + ++
Sbjct: 133 SYNPNDTCPASCAKSTQKCSS---------CAPIIGEY---------------AGEVLRF 168
Query: 547 TGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
G +GL FSFTEI+GVWL R+RN +DP A+P FL
Sbjct: 169 VGGIGLFFSFTEILGVWLTYRYRNQKDPRANPSAFL 204
>sp|Q12999|SAS_HUMAN Sarcoma amplified sequence (Tetraspanin-31) (Tspan-31)
Length = 210
Score = 114 bits (286), Expect = 2e-25
Identities = 72/219 (32%), Positives = 109/219 (49%), Gaps = 1/219 (0%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LVS LLI A+ + +V+ VFL ++A G+ H
Sbjct: 11 NALCALNVVYMLVSLLLIGVAAWGKGLGLVSSIHIIGGVIAVGVFLLLIAVAGLVGAVNH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGW-KNSDHAQIIVMKTFNCC 357
+QV QF I+C CLA+N + +++ W S+ + + ++F+CC
Sbjct: 71 HQVLLFFYMIILGLVFIFQFVISCSCLAINRSKQTDVINASWWVMSNKTRDELERSFDCC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCPCQQCWKMLQYSLNKA 537
GL NLT + CT I + + CQ C + ++A
Sbjct: 131 GLF---------------NLTTLY---QQDYDFCTA-ICKSQSPTCQMCGEKFLKHSDEA 171
Query: 538 VKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
+K+ G VGL FSFTEI+GVWLA+RFRN +DP A+P FL
Sbjct: 172 LKILGGVGLFFSFTEILGVWLAMRFRNQKDPRANPSAFL 210
>sp|Q5XHG6|SAS1_XENLA Sarcoma amplified sequence homolog 1
Length = 212
Score = 113 bits (283), Expect = 5e-25
Identities = 70/223 (31%), Positives = 106/223 (47%), Gaps = 5/223 (2%)
Frame = +1
Query: 1 SSLFALNIIYILVSFLLILFGAYARLSAIVTXXXXXXXXXXXXVFLAIVASLGIFATSKH 180
++L ALN++Y+LV LLI A+ + IV+ VFL ++A +G+ H
Sbjct: 11 NALCALNVVYMLVGLLLIGVAAWGKGFGIVSSIHIIGGVIAIGVFLLLIAIIGLIGAVSH 70
Query: 181 NQVAXXXXXXXXXXXXXVQFSIACVCLAVNDKIEENLVRQGWKN-SDHAQIIVMKTFNCC 357
+QV QF ++C CLA+N +E + W+ S+ ++ + +T CC
Sbjct: 71 HQVMLFIYMVVLILVFIFQFIVSCSCLAMNRSQQEYFLNTTWRRMSNETRLNLEETLECC 130
Query: 358 GLMESDLDNPSELKCKLANLTCCKGFPANETRCCTGVISRYEDCP----CQQCWKMLQYS 525
G + N T + + C+ V CP C C +
Sbjct: 131 GFL---------------NTTEARELFNKDVALCSHV------CPDPHKCLSCGDKMLNH 169
Query: 526 LNKAVKVTGAVGLVFSFTEIIGVWLAIRFRNMRDPIADPKLFL 654
++A+K+ G VGL FSFTEI+GVWLA RFRN +DP A+P FL
Sbjct: 170 ADEALKILGGVGLFFSFTEILGVWLAFRFRNQKDPRANPSAFL 212
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,853,452
Number of Sequences: 369166
Number of extensions: 1515874
Number of successful extensions: 3158
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3039
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3145
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6510836890
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)