Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00448 (975 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P09194|PHLC_TRYBB Variant-surface-glycoprotein phospholi... 84 6e-16 sp|O15886|PHLC_TRYCR Variant-surface-glycoprotein phospholi... 75 3e-13 sp|P34024|PLC_LISMO 1-phosphatidylinositol phosphodiesteras... 56 1e-07 sp|P14262|PLC_BACCE 1-phosphatidylinositol phosphodiesteras... 49 3e-05 sp|P08954|PLC_BACTU 1-phosphatidylinositol phosphodiesteras... 48 4e-05 sp|P45723|PLC_STAAU 1-phosphatidylinositol phosphodiesteras... 45 3e-04 sp|O07664|HPRK_ENTFA HPr kinase/phosphorylase (HPrK/P) (HPr... 32 2.7 sp|P44207|YE76_HAEIN Putative HTH-type transcriptional regu... 31 6.0 sp|Q03306|PKH3_YEAST Serine/threonine-protein kinase PKH3 (... 31 6.0 sp|P13010|KU86_HUMAN ATP-dependent DNA helicase II, 80 kDa ... 30 7.9
>sp|P09194|PHLC_TRYBB Variant-surface-glycoprotein phospholipase C (VSG lipase) (Glycosylphosphatidylinositol-specific phospholipase C) (GPI-PLC) Length = 358 Score = 84.0 bits (206), Expect = 6e-16 Identities = 65/233 (27%), Positives = 112/233 (48%), Gaps = 14/233 (6%) Frame = +3 Query: 87 YNPSDWMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKL----ISIF 254 ++P WMS+ ++ K + + + G H++ T+ I S DA + + L + Sbjct: 7 WSPQSWMSDTRSSIEKKCIGQVYMVGAHNAGTHGIQMFSPFGLDAPEKLRSLPPYVTFLL 66 Query: 255 GSWAVSVISRWAKAQDLDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLC 434 V V SRW + Q+L L+ G+RY D+R I+ N+IY+ H S +++ L Sbjct: 67 RFLTVGVSSRWGRCQNLSIRQLLDHGVRYLDLRMNISPDQENKIYTTHFHISVPLQEVLK 126 Query: 435 AINNFLKT--HQKEVVLLDLNHFYNFTQ-HDHMRLLHYLETIFSDKLVPYSRTIPT-LSE 602 + +FL T E V+LD HFY F + H R + L+ + + +P + ++ T L Sbjct: 127 DVKDFLTTPASANEFVILDFLHFYGFNESHTMKRFVEELQAL-EEFYIPTTVSLTTPLCN 185 Query: 603 LWETNHRVFVFYHCENVHKPYLWPGY------TIPSPWPNTDKLSMLMKFLSE 743 LW++ R+F+ V +PY+ Y + S W N +L+ L+ L E Sbjct: 186 LWQSTRRIFL------VVRPYVEYPYARLRSVALKSIWVNQMELNDLLDRLEE 232
>sp|O15886|PHLC_TRYCR Variant-surface-glycoprotein phospholipase C (VSG lipase) (Glycosylphosphatidylinositol-specific phospholipase C) (GPI-PLC) Length = 380 Score = 75.1 bits (183), Expect = 3e-13 Identities = 57/229 (24%), Positives = 97/229 (42%), Gaps = 12/229 (5%) Frame = +3 Query: 87 YNPSDWMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKLISIFGSWA 266 ++P WM +L + ++ + + G+HD+ +Y ++ S DA ++ S+F S Sbjct: 13 WHPQSWMHDLRSFIGEMAITQVCFVGSHDAASYGVSKDSPFGADAPGFLLG-DSVFASLL 71 Query: 267 V----SVISRWAKAQDLDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLC 434 + + W++ Q + QLN G+RY D+R A N D + +Y+ H S + D L Sbjct: 72 RFLFRGICASWSRCQWMSVRAQLNHGVRYLDMRVATNPEDASRLYTLHHQISVPLADVLE 131 Query: 435 AINNFLK--THQKEVVLLDLNHFYNFTQHDHMRLLHYLETIFSDKLVPYSRTIPT-LSEL 605 + FL E ++LD H Y D SD+ +P + T L L Sbjct: 132 DVKAFLNDPLSADEFIVLDFQHLYLTDDSDGKGKFFRELDRLSDRFIPVDVPLTTPLEFL 191 Query: 606 WETNHRVFVFYHCENVHKPYLWPGYTIPSP-----WPNTDKLSMLMKFL 737 W + R +F + +P I S W N + L L++ L Sbjct: 192 WRASSRRRIFLVVGSGEDESPYPAARIRSKCMVSRWVNENSLRKLLEAL 240
>sp|P34024|PLC_LISMO 1-phosphatidylinositol phosphodiesterase precursor (Phosphatidylinositol diacylglycerol-lyase) (Phosphatidylinositol-specific phospholipase C) (PI-PLC) Length = 317 Score = 56.2 bits (134), Expect = 1e-07 Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 4/172 (2%) Frame = +3 Query: 102 WMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKLISIFGSWAVSVIS 281 WMS LP+T L ++IPGTHD+ +Y G ++ Sbjct: 48 WMSALPDTTN---LAALSIPGTHDTMSYN----------------------GDITWTLTK 82 Query: 282 RWAKAQDLDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLCAINNFLKTH 461 A+ Q + Y QL AGIRY DIR+ +D IY + ++ L I FLK + Sbjct: 83 PLAQTQTMSLYQQLEAGIRYIDIRA----KDNLNIYHGPIFLNASLSGVLETITQFLKKN 138 Query: 462 QKEVVLLDLNHFYNFTQHDHMRLLH----YLETIFSDKLVPYSRTIPTLSEL 605 KE +++ L N R+ Y + ++ S IPTL ++ Sbjct: 139 PKETIIMRLKDEQNSNDSFDYRIQPLINIYKDYFYTTPRTDTSNKIPTLKDV 190
>sp|P14262|PLC_BACCE 1-phosphatidylinositol phosphodiesterase precursor (Phosphatidylinositol diacylglycerol-lyase) (Phosphatidylinositol-specific phospholipase C) (PI-PLC) Length = 329 Score = 48.5 bits (114), Expect = 3e-05 Identities = 36/137 (26%), Positives = 59/137 (43%) Frame = +3 Query: 90 NPSDWMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKLISIFGSWAV 269 N S WM +P+++ PL I+IPGTHDS T+K+ + IK + Sbjct: 40 NWSKWMQPIPDSI---PLARISIPGTHDSGTFKLQN-----------PIKQV-------- 77 Query: 270 SVISRWAKAQDLDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLCAINNF 449 W Q+ D Q++ G R FDIR + D + ++ + + + F Sbjct: 78 -----WGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQF 132 Query: 450 LKTHQKEVVLLDLNHFY 500 LK + E +++ L Y Sbjct: 133 LKDNPSETIIMSLKKEY 149
>sp|P08954|PLC_BACTU 1-phosphatidylinositol phosphodiesterase precursor (Phosphatidylinositol diacylglycerol-lyase) (Phosphatidylinositol-specific phospholipase C) (PI-PLC) Length = 329 Score = 48.1 bits (113), Expect = 4e-05 Identities = 36/137 (26%), Positives = 58/137 (42%) Frame = +3 Query: 90 NPSDWMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKLISIFGSWAV 269 N S WM +P+ + PL I+IPGTHDS T+K+ + IK + Sbjct: 40 NWSKWMQPIPDNI---PLARISIPGTHDSGTFKLQN-----------PIKQV-------- 77 Query: 270 SVISRWAKAQDLDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLCAINNF 449 W Q+ D Q++ G R FDIR + D + ++ + + + F Sbjct: 78 -----WGMTQEYDFRYQMDHGARIFDIRGRLTDDNTIVLHHGPLYLYVTLHEFINEAKQF 132 Query: 450 LKTHQKEVVLLDLNHFY 500 LK + E +++ L Y Sbjct: 133 LKDNPSETIIMSLKKEY 149
>sp|P45723|PLC_STAAU 1-phosphatidylinositol phosphodiesterase precursor (Phosphatidylinositol diacylglycerol-lyase) (Phosphatidylinositol-specific phospholipase C) (PI-PLC) Length = 311 Score = 45.1 bits (105), Expect = 3e-04 Identities = 47/182 (25%), Positives = 71/182 (39%), Gaps = 11/182 (6%) Frame = +3 Query: 90 NPSDWMSNLPETLTKLPLNWIAIPGTHDSFTYKINSHSHVSPDAEDIVIKLISIFGSWAV 269 +P +WMS L + +N IPG+HDS ++ + Sbjct: 17 SPENWMSKLDDGKHLTEIN---IPGSHDSGSFTLKD------------------------ 49 Query: 270 SVISRWAKAQDLDPYGQLNAGIRYFDIR---SAIN--DRDGNEIYSCHSLFSGNIRDDLC 434 V S WAK QD D Q+ +G+R+FDIR SA N +Y H L G DD Sbjct: 50 PVKSVWAKTQDKDYLTQMKSGVRFFDIRGRASADNMISVHHGMVYLHHEL--GKFLDD-- 105 Query: 435 AINNFLKTHQKEVVLLDLNHFYNF------TQHDHMRLLHYLETIFSDKLVPYSRTIPTL 596 +L + E +++ + Y+ T + R +Y + + S PTL Sbjct: 106 -AKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYYYNNPQYQNLFYTGSNANPTL 164 Query: 597 SE 602 E Sbjct: 165 KE 166
>sp|O07664|HPRK_ENTFA HPr kinase/phosphorylase (HPrK/P) (HPr(Ser) kinase/phosphorylase) Length = 311 Score = 32.0 bits (71), Expect = 2.7 Identities = 13/51 (25%), Positives = 29/51 (56%) Frame = +3 Query: 435 AINNFLKTHQKEVVLLDLNHFYNFTQHDHMRLLHYLETIFSDKLVPYSRTI 587 ++N +KT + L+L ++N+ HD ++L E F+++++P R + Sbjct: 25 SLNRTIKTGEISRPGLELTGYFNYYSHDRLQLFGSKEITFAERMMPEERLL 75
>sp|P44207|YE76_HAEIN Putative HTH-type transcriptional regulator HI1476 Length = 239 Score = 30.8 bits (68), Expect = 6.0 Identities = 20/69 (28%), Positives = 32/69 (46%), Gaps = 6/69 (8%) Frame = +3 Query: 303 LDPYGQLNAGIRYFDIRSAINDRDGNEIYSCHSLFSGNIRDDLCAI-----NNFLKT-HQ 464 +D Y +N + I DG E YS L S ++ D CA+ N+ L T + Sbjct: 104 IDSYSSINVSAGFGSFNEGITQPDGQEPYSDELLTSLGVKADNCAVFWANGNSMLPTINN 163 Query: 465 KEVVLLDLN 491 + +L+DL+ Sbjct: 164 YDQMLVDLS 172
>sp|Q03306|PKH3_YEAST Serine/threonine-protein kinase PKH3 (Pkb-activating kinase homolog 3) Length = 898 Score = 30.8 bits (68), Expect = 6.0 Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 2/36 (5%) Frame = +3 Query: 45 FSRFTRKSYVHLQNYNPSDWMSNLP--ETLTKLPLN 146 F+ TRK ++ L+ Y W +LP TL+K+P N Sbjct: 601 FNELTRKGFLILEKYKNRIWFISLPSYSTLSKIPFN 636
>sp|P13010|KU86_HUMAN ATP-dependent DNA helicase II, 80 kDa subunit (Lupus Ku autoantigen protein p86) (Ku86) (Ku80) (86 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box binding factor 85 kDa subunit) (CTCBF) (CTC85) (Nuclear factor IV) (DNA-repair protein XRCC5) Length = 732 Score = 30.4 bits (67), Expect = 7.9 Identities = 13/31 (41%), Positives = 19/31 (61%) Frame = +3 Query: 441 NNFLKTHQKEVVLLDLNHFYNFTQHDHMRLL 533 NNFLK Q++V + LNHF+ D + L+ Sbjct: 656 NNFLKALQEKVEIKQLNHFWEIVVQDGITLI 686
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 122,324,432 Number of Sequences: 369166 Number of extensions: 2686501 Number of successful extensions: 6197 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5947 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6192 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10191921135 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)