Planaria EST Database

DrC_00445

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00445
         (1332 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q5RFM9|FTHFD_PONPY  10-formyltetrahydrofolate dehydrogena...   580   e-165
sp|Q8R0Y6|FTHFD_MOUSE  10-formyltetrahydrofolate dehydrogena...   576   e-164
sp|O75891|FTHFD_HUMAN  10-formyltetrahydrofolate dehydrogena...   575   e-163
sp|P28037|FTHFD_RAT  10-formyltetrahydrofolate dehydrogenase...   572   e-163
sp|Q8MI17|AL1A1_RABIT  Retinal dehydrogenase 1 (RalDH1) (RAL...   352   1e-96
sp|Q28399|ALDH1_ELEED  Aldehyde dehydrogenase, cytosolic 1 (...   352   1e-96
sp|Q29490|ALDH1_MACPR  Aldehyde dehydrogenase, cytosolic 1 (...   351   3e-96
sp|P00352|AL1A1_HUMAN  Retinal dehydrogenase 1 (RalDH1) (RAL...   350   4e-96
sp|P51977|AL1A1_SHEEP  Retinal dehydrogenase 1 (RalDH1) (RAL...   350   4e-96
sp|P48644|AL1A1_BOVIN  Retinal dehydrogenase 1 (RalDH1) (RAL...   350   5e-96

>sp|Q5RFM9|FTHFD_PONPY 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (Aldehyde
            dehydrogenase 1 family member L1)
          Length = 902

 Score =  580 bits (1496), Expect = e-165
 Identities = 280/443 (63%), Positives = 343/443 (77%), Gaps = 1/443 (0%)
 Frame = +2

Query: 5    RLVEEIKFAFD-VELKIDHIYLYNTFDSLFRWIVLKKRGGGVSKKLIYDAVIINANKITF 181
            RLVEE+K   D +EL+ + +Y+ +TF    + +V K RG     +   D V +  NK T 
Sbjct: 359  RLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTI 418

Query: 182  PVPHQLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGEWG 361
             +PHQLFI  EFVD+E  K YET NP D SVIC+VS +               FE G WG
Sbjct: 419  RIPHQLFIGGEFVDAEGAKTYETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWG 478

Query: 362  KMNARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCD 541
            K++AR+RGR++Y+LADL+E+H EELAT+E+LD+GAVYTLALKTHVGMSI+TFRYFAGWCD
Sbjct: 479  KISARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCD 538

Query: 542  KIQGSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKP 721
            KIQGS IPI+ ARPN+NL++T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KP
Sbjct: 539  KIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKP 598

Query: 722  AQVTPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTI 901
            AQVTPLT+LKF E  ++AG P GV+NVLPGSG++ G  +S+H DVRK+GFTGST +G+ I
Sbjct: 599  AQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHI 658

Query: 902  MTSCAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTR 1081
            M SCA SN+KK SLELGGKSPLIIF+DCD+ KAV+   SSVFFNKGENCIAAGRLF++  
Sbjct: 659  MKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDS 718

Query: 1082 IHDLFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKR 1261
            IHD F++ ++EEV KMK+GDPLDR  DHGPQNH  HL KL+E+C  G KEGA LV GG +
Sbjct: 719  IHDEFVRRVVEEVRKMKVGDPLDRDTDHGPQNHHAHLMKLMEYCQRGVKEGATLVCGGNQ 778

Query: 1262 CDRKGYFLQPTVFTDVTDDMYIA 1330
              R G+F +PTVFTDV D M+IA
Sbjct: 779  VPRPGFFFEPTVFTDVEDHMFIA 801

>sp|Q8R0Y6|FTHFD_MOUSE 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (Aldehyde
            dehydrogenase 1 family member L1)
          Length = 902

 Score =  576 bits (1484), Expect = e-164
 Identities = 277/443 (62%), Positives = 342/443 (77%), Gaps = 1/443 (0%)
 Frame = +2

Query: 5    RLVEEIKFAFD-VELKIDHIYLYNTFDSLFRWIVLKKRGGGVSKKLIYDAVIINANKITF 181
            RLVEE+K   D +EL+ + +Y+  TF    + +V K RG     + + + V     K+T 
Sbjct: 359  RLVEEVKELCDGLELENEDVYMATTFGDFIQLLVRKLRGEDGESECVINYVEKAVKKLTL 418

Query: 182  PVPHQLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGEWG 361
             +P+QLFI  EFVD+E  K Y T NP D SVIC+VS +               FE G WG
Sbjct: 419  QMPYQLFIGGEFVDAEGAKTYSTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWG 478

Query: 362  KMNARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCD 541
            K+NAR+RGR++Y+LADL+E+H EELAT+E+LD+GAVYTLALKTHVGMSI+TFRYFAGWCD
Sbjct: 479  KINARDRGRLLYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCD 538

Query: 542  KIQGSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKP 721
            KIQG+ IPI+ ARPN+NL++TKKEP+GVCGI+ PWNYPLMML+WK AACLAAGNTVV+KP
Sbjct: 539  KIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKP 598

Query: 722  AQVTPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTI 901
            AQVTPLT+LKF E  ++AG P GV+N+LPGSG++ G  +S+H DVRK+GFTGST +G+ I
Sbjct: 599  AQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHI 658

Query: 902  MTSCAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTR 1081
            M SCA SN+KK SLELGGKSPLIIF+DCD+ KAV+   SSVFFNKGENCIAAGRLF++  
Sbjct: 659  MKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDS 718

Query: 1082 IHDLFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKR 1261
            IHD F++ ++EEV KMKIG+PLDR  +HGPQNHE HL KL+E+C  G KEGA LV GG +
Sbjct: 719  IHDQFVQKVVEEVGKMKIGNPLDRDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQ 778

Query: 1262 CDRKGYFLQPTVFTDVTDDMYIA 1330
              R G+F QPTVFTDV D MYIA
Sbjct: 779  VPRPGFFFQPTVFTDVEDHMYIA 801

>sp|O75891|FTHFD_HUMAN 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (Aldehyde
            dehydrogenase 1 family member L1)
          Length = 902

 Score =  575 bits (1481), Expect = e-163
 Identities = 279/443 (62%), Positives = 342/443 (77%), Gaps = 1/443 (0%)
 Frame = +2

Query: 5    RLVEEIKFAFD-VELKIDHIYLYNTFDSLFRWIVLKKRGGGVSKKLIYDAVIINANKITF 181
            RLVEE+K   D +EL+ + +Y+ +TF    + +V K RG     +   D V +  NK T 
Sbjct: 359  RLVEEVKELCDGLELENEDVYMASTFGDFIQLLVRKLRGDDEEGECSIDYVEMAVNKRTV 418

Query: 182  PVPHQLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGEWG 361
             +PHQLFI  EFVD+E  K  ET NP D SVIC+VS +               FE G WG
Sbjct: 419  RMPHQLFIGGEFVDAEGAKTSETINPTDGSVICQVSLAQVTDVDKAVAAAKDAFENGRWG 478

Query: 362  KMNARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCD 541
            K++AR+RGR+MY+LADL+E+H EELAT+E+LD+GAVYTLALKTHVGMSI+TFRYFAGWCD
Sbjct: 479  KISARDRGRLMYRLADLMEQHQEELATIEALDAGAVYTLALKTHVGMSIQTFRYFAGWCD 538

Query: 542  KIQGSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKP 721
            KIQGS IPI+ ARPN+NL++T+KEP+GVCGII PWNYPLMML+WK AACLAAGNTVV+KP
Sbjct: 539  KIQGSTIPINQARPNRNLTLTRKEPVGVCGIIIPWNYPLMMLSWKTAACLAAGNTVVIKP 598

Query: 722  AQVTPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTI 901
            AQVTPLT+LKF E  ++AG P GV+NVLPGSG++ G  +S+H DVRK+GFTGST +G+ I
Sbjct: 599  AQVTPLTALKFAELTLKAGIPKGVVNVLPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHI 658

Query: 902  MTSCAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTR 1081
            M SCA SN+KK SLELGGKSPLIIF+DCD+ KAV+   SSVFFNKGENCIAAGRLF++  
Sbjct: 659  MKSCAISNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEDS 718

Query: 1082 IHDLFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKR 1261
            IHD F++ ++EEV KMK+G+PLDR  DHGPQNH  HL KL+E+C  G KEGA LV GG +
Sbjct: 719  IHDEFVRRVVEEVRKMKVGNPLDRDTDHGPQNHHAHLVKLMEYCQHGVKEGATLVCGGNQ 778

Query: 1262 CDRKGYFLQPTVFTDVTDDMYIA 1330
              R G+F +PTVFTDV D M+IA
Sbjct: 779  VPRPGFFFEPTVFTDVEDHMFIA 801

>sp|P28037|FTHFD_RAT 10-formyltetrahydrofolate dehydrogenase (10-FTHFDH) (Aldehyde
            dehydrogenase 1 family member L1) (FBP-CI)
          Length = 902

 Score =  572 bits (1475), Expect = e-163
 Identities = 275/443 (62%), Positives = 342/443 (77%), Gaps = 1/443 (0%)
 Frame = +2

Query: 5    RLVEEIKFAFD-VELKIDHIYLYNTFDSLFRWIVLKKRGGGVSKKLIYDAVIINANKITF 181
            RLVEE+K   D +EL+ + +Y+  TF    + +V K RG     + + + V    NK+T 
Sbjct: 359  RLVEEVKELCDGLELENEDVYMATTFREFIQLLVRKLRGEDDESECVINYVERAVNKLTL 418

Query: 182  PVPHQLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGEWG 361
             +P+QLFI  EFVD+E  K Y T NP D SVIC+VS +               FE G WG
Sbjct: 419  QMPYQLFIGGEFVDAEGSKTYNTINPTDGSVICQVSLAQVSDVDKAVAAAKEAFENGLWG 478

Query: 362  KMNARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCD 541
            K+NAR+RGR++Y+LAD++E+H EELAT+E+LD GAVYTLALKTHVGMSI+TFRYFAGWCD
Sbjct: 479  KINARDRGRLLYRLADVMEQHQEELATIEALDRGAVYTLALKTHVGMSIQTFRYFAGWCD 538

Query: 542  KIQGSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKP 721
            KIQG+ IPI+ ARPN+NL++TKKEP+GVCGI+ PWNYPLMML+WK AACLAAGNTVV+KP
Sbjct: 539  KIQGATIPINQARPNRNLTLTKKEPVGVCGIVIPWNYPLMMLSWKTAACLAAGNTVVIKP 598

Query: 722  AQVTPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTI 901
            AQVTPLT+LKF E  ++AG P GV+N+LPGSG++ G  +S+H DVRK+GFTGST +G+ I
Sbjct: 599  AQVTPLTALKFAELTLKAGIPKGVVNILPGSGSLVGQRLSDHPDVRKIGFTGSTEVGKHI 658

Query: 902  MTSCAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTR 1081
            M SCA SN+KK SLELGGKSPLIIF+DCD+ KAV+   SSVFFNKGENCIAAGRLF++  
Sbjct: 659  MKSCALSNVKKVSLELGGKSPLIIFADCDLNKAVQMGMSSVFFNKGENCIAAGRLFVEES 718

Query: 1082 IHDLFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKR 1261
            IH+ F++ ++EEV KMKIG+PL+R  +HGPQNHE HL KL+E+C  G KEGA LV GG +
Sbjct: 719  IHNQFVQKVVEEVEKMKIGNPLERDTNHGPQNHEAHLRKLVEYCQRGVKEGATLVCGGNQ 778

Query: 1262 CDRKGYFLQPTVFTDVTDDMYIA 1330
              R G+F QPTVFTDV D MYIA
Sbjct: 779  VPRPGFFFQPTVFTDVEDHMYIA 801

>sp|Q8MI17|AL1A1_RABIT Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
            family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
            (ALHDII) (ALDH-E1)
          Length = 496

 Score =  352 bits (903), Expect = 1e-96
 Identities = 177/380 (46%), Positives = 246/380 (64%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            ++FINNE+ DS SGK +   NPA E  IC +                  F+ G  W  M+
Sbjct: 17   KIFINNEWHDSVSGKKFPVLNPATEEQICLIEEGDKADVDKAVKAARQAFQIGSPWRTMD 76

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERGR++YKLADL+E+    LAT+ESL++G ++  A    +G  I+T RY AGW DKIQ
Sbjct: 77   ASERGRLLYKLADLIERDRLLLATMESLNAGKLFPNAYLMDLGGCIKTLRYCAGWADKIQ 136

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  +P+           T+ EP+GVCG I PWN+PL+ML WK+   L+ GNTV++KPA+ 
Sbjct: 137  GRTMPMDG----DFFCYTRHEPVGVCGQIIPWNFPLVMLIWKIGPALSCGNTVIVKPAEQ 192

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H D+ K+ FTGST +G+ I  +
Sbjct: 193  TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 252

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
              KSNLK+ +LELGGKSP I+F+D D++ AV+ A   VF+++G+ CIAA RLF++  I+D
Sbjct: 253  AGKSNLKRVTLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYD 312

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K  +G+PL   V+ GPQ  +   +K+L+    G+KEGA+L  GG     
Sbjct: 313  EFVRRSVERAKKYVLGNPLAPEVNQGPQIDKEQYNKILDLIESGKKEGAKLECGGGPWGN 372

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPTVF++VTD+M IA
Sbjct: 373  KGYFIQPTVFSNVTDEMRIA 392

>sp|Q28399|ALDH1_ELEED Aldehyde dehydrogenase, cytosolic 1 (ALDH class 1) (ETA-crystallin)
          Length = 501

 Score =  352 bits (903), Expect = 1e-96
 Identities = 179/380 (47%), Positives = 247/380 (65%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            +LFINNE+ +S SGK +   NPA E  IC V  +               F+ G  W  M+
Sbjct: 22   KLFINNEWHESVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKAAREAFQMGSPWRTMD 81

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERG+++YKLADL+E+    LATLES+++G V+  A    +   I+  RY AGW DKIQ
Sbjct: 82   ASERGQLIYKLADLIERDRLLLATLESINAGKVFASAYLMDLDYCIKALRYCAGWADKIQ 141

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  IP+      +  S T+ EPIGVCG+I PWN P+++LA K+   L  GNTV++KPA+ 
Sbjct: 142  GRTIPVDG----EFFSYTRHEPIGVCGLIFPWNAPMILLACKIGPALCCGNTVIVKPAEQ 197

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H DV K+ FTGST +G+ I  +
Sbjct: 198  TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMIQEA 257

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
             AKSNLK+ +LELG K+P I+F+D D++ AV+ A   VF N+G++CIAA +LF++  I+D
Sbjct: 258  AAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAASKLFVEEAIYD 317

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K   G+PL   V+HGPQ ++   +K++E    G+KEGA+L  GG     
Sbjct: 318  EFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGAKLECGGGPWGN 377

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPTVF++VTDDM IA
Sbjct: 378  KGYFIQPTVFSNVTDDMRIA 397

>sp|Q29490|ALDH1_MACPR Aldehyde dehydrogenase, cytosolic 1 (ALDH class 1) (ETA-crystallin)
          Length = 501

 Score =  351 bits (900), Expect = 3e-96
 Identities = 178/380 (46%), Positives = 246/380 (64%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            +LFINNE+ DS SGK +   NPA E  IC V  +               F+ G  W  M+
Sbjct: 22   KLFINNEWHDSVSGKTFPVFNPATEEKICEVEEADKEDVDKAVKAAREAFQMGSPWRTMD 81

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERG+++YKLADL+E+    LATLES+++G ++  A    +   I+  RY AGW DKIQ
Sbjct: 82   ASERGQLIYKLADLIERDRLLLATLESINAGKIFASAYLMDLDYCIKVLRYCAGWADKIQ 141

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  IP+      +  S T+ EPIGVCG I PWN P+++LA K+   L  GNTV++KPA+ 
Sbjct: 142  GRTIPVDG----EFFSYTRHEPIGVCGQIFPWNAPMILLACKIGPALCCGNTVIVKPAEQ 197

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H DV K+ FTGST +G+ I  +
Sbjct: 198  TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKMIQEA 257

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
             AKSNLK+ +LELG K+P I+F+D D++ AV+ A   VF N+G++CIAA +LF++  I+D
Sbjct: 258  AAKSNLKRVTLELGAKNPCIVFADADLDSAVEFAHQGVFTNQGQSCIAASKLFVEETIYD 317

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K   G+PL   V+HGPQ ++   +K++E    G+KEGA+L  GG     
Sbjct: 318  EFVQRSVERAKKYVFGNPLTPGVNHGPQINKAQHNKIMELIESGKKEGAKLECGGGPWGN 377

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPT+F++VTDDM IA
Sbjct: 378  KGYFIQPTIFSNVTDDMRIA 397

>sp|P00352|AL1A1_HUMAN Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
            family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
            (ALHDII) (ALDH-E1)
          Length = 501

 Score =  350 bits (899), Expect = 4e-96
 Identities = 178/380 (46%), Positives = 244/380 (64%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            ++FINNE+ DS SGK +   NPA E  +C+V                  F+ G  W  M+
Sbjct: 22   KIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMD 81

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERGR++YKLADL+E+    LAT+ES++ G +Y+ A    +   I+T RY AGW DKIQ
Sbjct: 82   ASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQ 141

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  IPI         + T+ EPIGVCG I PWN+PL+ML WK+   L+ GNTVV+KPA+ 
Sbjct: 142  GRTIPIDG----NFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQ 197

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H D+ K+ FTGST +G+ I  +
Sbjct: 198  TPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEA 257

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
              KSNLK+ +LELGGKSP I+ +D D++ AV+ A   VF+++G+ CIAA R+F++  I+D
Sbjct: 258  AGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYD 317

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K  +G+PL   V  GPQ  +    K+L+    G+KEGA+L  GG     
Sbjct: 318  EFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPTVF++VTD+M IA
Sbjct: 378  KGYFVQPTVFSNVTDEMRIA 397

>sp|P51977|AL1A1_SHEEP Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
            family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
            (ALHDII) (ALDH-E1)
          Length = 501

 Score =  350 bits (899), Expect = 4e-96
 Identities = 178/380 (46%), Positives = 242/380 (63%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            ++FINNE+  S SGK +   NPA E  +C V                  F+ G  W  M+
Sbjct: 22   KIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAARQAFQIGSPWRTMD 81

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERGR++ KLADL+E+    LAT+E+++ G +++ A    +G  I+T RY AGW DKIQ
Sbjct: 82   ASERGRLLNKLADLIERDRLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQ 141

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  IP+         + T+ EP+GVCG I PWN+PL+M  WK+   L+ GNTVV+KPA+ 
Sbjct: 142  GRTIPMDG----NFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQ 197

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H DV K+ FTGST +G+ I  +
Sbjct: 198  TPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEA 257

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
              KSNLK+ SLELGGKSP I+F+D D++ AV+ A   VF+++G+ CIAA RLF++  I+D
Sbjct: 258  AGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYD 317

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K  +G+PL   V  GPQ  +    K+L+    G+KEGA+L  GG     
Sbjct: 318  EFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGN 377

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPTVF+DVTDDM IA
Sbjct: 378  KGYFIQPTVFSDVTDDMRIA 397

>sp|P48644|AL1A1_BOVIN Retinal dehydrogenase 1 (RalDH1) (RALDH 1) (Aldehyde dehydrogenase
            family 1 member A1) (Aldehyde dehydrogenase, cytosolic)
            (ALHDII) (ALDH-E1)
          Length = 501

 Score =  350 bits (898), Expect = 5e-96
 Identities = 178/380 (46%), Positives = 242/380 (63%), Gaps = 1/380 (0%)
 Frame = +2

Query: 194  QLFINNEFVDSESGKDYETKNPADESVICRVSFSSXXXXXXXXXXXXXXFEYGE-WGKMN 370
            ++FINNE+  S SGK +   NPA E  +C V                  F+ G  W  M+
Sbjct: 22   KIFINNEWHSSVSGKKFPVFNPATEEKLCEVEEGDKEDVDKAVKAVRQAFQIGSPWRTMD 81

Query: 371  ARERGRIMYKLADLLEKHAEELATLESLDSGAVYTLALKTHVGMSIETFRYFAGWCDKIQ 550
            A ERGR++ KLADL+E+    LAT+E+++ G +++ A    +G  I+T RY AGW DKIQ
Sbjct: 82   ASERGRLLNKLADLIERDHLLLATMEAMNGGKLFSNAYLMDLGGCIKTLRYCAGWADKIQ 141

Query: 551  GSVIPISNARPNKNLSITKKEPIGVCGIITPWNYPLMMLAWKMAACLAAGNTVVMKPAQV 730
            G  IP+         + T+ EP+GVCG I PWN+PL+M  WK+   L+ GNTVV+KPA+ 
Sbjct: 142  GRTIPMDG----NFFTYTRSEPVGVCGQIIPWNFPLLMFLWKIGPALSCGNTVVVKPAEQ 197

Query: 731  TPLTSLKFCEFVVEAGFPPGVINVLPGSGAITGTAISEHGDVRKLGFTGSTGIGQTIMTS 910
            TPLT+L     + EAGFPPGV+N++PG G   G AIS H DV K+ FTGST +G+ I  +
Sbjct: 198  TPLTALHMGSLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDVDKVAFTGSTEVGKLIKEA 257

Query: 911  CAKSNLKKCSLELGGKSPLIIFSDCDIEKAVKSACSSVFFNKGENCIAAGRLFIDTRIHD 1090
              KSNLK+ SLELGGKSP I+F+D D++ AV+ A   VF+++G+ CIAA RLF++  I+D
Sbjct: 258  AGKSNLKRVSLELGGKSPCIVFADADLDNAVEFAHQGVFYHQGQCCIAASRLFVEESIYD 317

Query: 1091 LFLKLIIEEVSKMKIGDPLDRSVDHGPQNHEIHLHKLLEFCNIGEKEGARLVYGGKRCDR 1270
             F++  +E   K  +G+PL   V  GPQ  +    K+L+    G+KEGA+L  GG     
Sbjct: 318  EFVRRSVERAKKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGN 377

Query: 1271 KGYFLQPTVFTDVTDDMYIA 1330
            KGYF+QPTVF+DVTDDM IA
Sbjct: 378  KGYFIQPTVFSDVTDDMRIA 397

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 163,692,255
Number of Sequences: 369166
Number of extensions: 3562704
Number of successful extensions: 10605
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9593
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10188
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 15560117510
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00445

  1. Dr_sW_011_K20
  2. Dr_sW_028_M21