Planaria EST Database


DrC_00427

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00427
         (1550 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P05997|CO5A2_HUMAN  Collagen alpha 2(V) chain precursor        164   6e-40
sp|P12107|CA1B_HUMAN  Collagen alpha 1(XI) chain precursor        160   9e-39
sp|Q01149|CO1A2_MOUSE  Collagen alpha 2(I) chain precursor        158   4e-38
sp|P02458|CO2A1_HUMAN  Collagen alpha 1(II) chain precursor ...   157   1e-37
sp|P20909|CA1B_RAT  Collagen alpha 1(XI) chain precursor          156   2e-37
sp|P02465|CO1A2_BOVIN  Collagen alpha 2(I) chain precursor        154   7e-37
sp|O46392|CO1A2_CANFA  Collagen alpha 2(I) chain precursor        152   3e-36
sp|P02467|CO1A2_CHICK  Collagen alpha 2(I) chain precursor        151   6e-36
sp|P28481|CO2A1_MOUSE  Collagen alpha 1(II) chain precursor ...   150   1e-35
sp|P02457|CA11_CHICK  Collagen alpha 1(I) chain precursor         149   3e-35
>sp|P05997|CO5A2_HUMAN Collagen alpha 2(V) chain precursor
          Length = 1496

 Score =  164 bits (415), Expect = 6e-40
 Identities = 127/426 (29%), Positives = 179/426 (42%), Gaps = 20/426 (4%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            GR GK G PGP G  GD G  G                    GD G+ G  G  G  GL 
Sbjct: 1110 GRAGKRGLPGPQGPRGDKGDHGDR------------------GDRGQKGHRGFTGLQGLP 1151

Query: 419  GPPG---DAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXX 589
            GPPG   + GSAG  GP G +GPPGP G  G +G  GP G                    
Sbjct: 1152 GPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPLGPPGVRGSVGEAGPEGPP 1211

Query: 590  XXXXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPN 769
                                    + D       +   D   +F  D+   + K+  DP 
Sbjct: 1212 GEPGPPGPPGPPGHLTAALGDIMGHYD-------ESMPDPLPEFTEDQAAPDDKNKTDPG 1264

Query: 770  DEDEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKD 949
                 +   L  LS+ ++ +  P GSK +PAR+C D++  ++ K +G Y+IDPN G  +D
Sbjct: 1265 -----VHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVED 1319

Query: 950  AIYVFCNFEKLETCIEPEVSNYKKTSYMKSHSS-----WFSILASLNKQVSY------KI 1096
            AI V+CN E  ETCI    S+  + ++  S S      W+ +  +   Q +Y        
Sbjct: 1320 AIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNT 1379

Query: 1097 PKEQLVFLQLSSESTSQNFTLSCDN-IGLVSDNSVNQEN----KYNNSLQLLGDDNQILT 1261
               Q+ FL+L S+  SQN T  C N +G + D + N +     K  N L +  + N    
Sbjct: 1380 AITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGN---- 1435

Query: 1262 VNNDDDLFQYQIIEDNC-KGKSSSGRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVE 1438
                   F+Y +++D C K   + G+ V +       RLPI D     +  + Q + GVE
Sbjct: 1436 -----IRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQ-EFGVE 1489

Query: 1439 IGPVCF 1456
            IGPVCF
Sbjct: 1490 IGPVCF 1495

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 44/107 (41%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G+ G+ GPPGP   +G PG PG                  +IG  G PG  G  G+ G  
Sbjct: 402 GQRGETGPPGP---VGSPGLPG------------------AIGTDGTPGPKGPTGSPGTS 440

Query: 419 GPPGDAGSAGNDGPKGSQGP---------PGPTGNIGPKGERGPKGV 532
           GPPG AG  G+ GP+GS GP         PG  G  GPKGE GP G+
Sbjct: 441 GPPGSAGPPGSPGPQGSTGPQGNSGLPGDPGFKGEAGPKGEPGPHGI 487

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 43/110 (39%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G DG PGP G  G PG  G                    G++G PGDPG  G AG 
Sbjct: 419 PGAIGTDGTPGPKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGNSGLPGDPGFKGEAGP 478

Query: 416 ------------IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                       IGPPG+ G  G  G  G+ GPPGP G  G  G RG  G
Sbjct: 479 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTLGPPGPVGERGAPGNRGFPG 528

 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 42/109 (38%), Positives = 48/109 (44%), Gaps = 12/109 (11%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G+ G  G PGP G  GDPG PG A                 +G  G PG PG+ G  G  
Sbjct: 606 GQPGTMGLPGPKGSNGDPGKPGEAGNPGVPGQRGAPGKDGKVGPYGPPGPPGLRGERGEQ 665

Query: 419 GPPGDAGSAGNDGPKGSQGP------------PGPTGNIGPKGERGPKG 529
           GPPG  G  G+ GP G  G             PG  G +GP+GERG  G
Sbjct: 666 GPPGPTGFQGHPGPPGPPGEGGKPGDQGVPGGPGAVGPLGPRGERGNPG 714

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 42/103 (40%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSG---KLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
           G  G+ GPPGP+G     G PG PG                   +G  GE G+PG  G  
Sbjct: 660 GERGEQGPPGPTGFQGHPGPPGPPGEGGKPGDQGVPGGPGAVGPLGPRGERGNPGERGEP 719

Query: 410 GLIGPPGDAGSAGN---DGPKGSQGPPGPTGNIGPKGERGPKG 529
           G+ G PG+ G AG    DGPKGS GP G  G+ GP G +G  G
Sbjct: 720 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPG 762

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 45/110 (40%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G SG  GDPGF G A                 IG  GE G  G  G+ G 
Sbjct: 452 PGPQGSTGPQGNSGLPGDPGFKGEAGPKGEPGPHGIQGP---IGPPGEEGKRGPRGDPGT 508

Query: 416 IGPPGDAG------------SAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           +GPPG  G            S G  GPKG+QG  GP G+ GPKG +G  G
Sbjct: 509 LGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 558

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 41/97 (42%), Positives = 46/97 (47%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G+DG PGP G +G  G PG                    G  G  GDPG  G AG  
Sbjct: 588 GAPGEDGRPGPPGSIGIKGQPGTMGLP---------------GPKGSNGDPGKPGEAGNP 632

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G PG  G+ G DG  G  GPPGP G  G +GE+GP G
Sbjct: 633 GVPGQRGAPGKDGKVGPYGPPGPPGLRGERGEQGPPG 669

 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 41/104 (39%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ G PG  G  G PG  G A                  G  G PG  G  G+AG
Sbjct: 853  QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAG 912

Query: 413  LIGPPGDAGSAGNDGP---KGSQGPPGPTGNIGPKGERGPKGVA 535
             +GPPG AG+ G  GP    G +GPPGP G+ G  G  G +G A
Sbjct: 913  RVGPPGPAGAPGPAGPLGEPGKEGPPGPRGDPGSHGRVGVRGPA 956

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 46/109 (42%), Positives = 49/109 (44%), Gaps = 12/109 (11%)
 Frame = +2

Query: 239  GRMGKDGP---PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
            G  G DGP   PGPSG  GD G PG                    G  GE G  G AGN 
Sbjct: 732  GGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND 791

Query: 410  GL------IGPPGDAG---SAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G       +GPPG AG     G  GP+G  GPPG  GN G +GE GP G
Sbjct: 792  GAGGLPGPLGPPGPAGLLGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 840

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 40/103 (38%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPG---RAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
           +PGR G+ G PG  G  G+PG  G   +                 SIG  G+PG  G+ G
Sbjct: 556 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIKGQPGTMGLPG 615

Query: 404 NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G PG  G AGN G  G +G PG  G +GP G  GP G+
Sbjct: 616 PKGSNGDPGKPGEAGNPGVPGQRGAPGKDGKVGPYGPPGPPGL 658

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 43/102 (42%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            GR+G  GP GP G  GD G PG                    G  G PG  G  G  GL 
Sbjct: 948  GRVGVRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP 1007

Query: 419  GP---PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GP   PG  G  G  G KG  GP GP G+ GP GE GP+G A
Sbjct: 1008 GPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1049

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 41/102 (40%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G+ G PG  G  G  G PG                  S GD G PG+PG+ G  GL
Sbjct: 512 PGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGL 571

Query: 416 IGPPGDAGSAGNDGP---KGSQGPPGPTGNIGPKGERGPKGV 532
            G PG  G  G  GP    G  G PGP G+IG KG+ G  G+
Sbjct: 572 TGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIKGQPGTMGL 613

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 42/110 (38%), Positives = 49/110 (44%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G+ G DGPPGP+G  G  G  G                    G AG PG  G  G  G
Sbjct: 970  EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP------GPAGTPGKVGPTGATG 1023

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGN---------IGPKGERGPKGVA 535
              GPPG  G  G++GP G  GP GP GN         +G +G+RG  G A
Sbjct: 1024 DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPA 1073

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 42/103 (40%), Positives = 48/103 (46%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G  GP GP G  G  G PG                    G+ G  G PG  G+ G
Sbjct: 727  EKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP---------GERGIAGTPGPKGDRG 777

Query: 413  LIGPPGDAGSAGNDGP---KGSQGPPGPTGNIGPKGERGPKGV 532
             IG  G  G+AGNDG     G  GPPGP G +G KGE GP+G+
Sbjct: 778  GIGEKGAEGTAGNDGAGGLPGPLGPPGPAGLLGEKGEPGPRGL 820

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 44/110 (40%), Positives = 49/110 (44%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G  G  GP G  G+PG  G                    G  GEPG+PG  G+AG
Sbjct: 811  EKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGSDGQPGVKGEPGEPGQKGDAG 870

Query: 413  LIGPPGDAGSAGNDGP---------KGSQGPPGPTGNIGPKGERGPKGVA 535
              GP G AGS G  GP         +G+QGPPG TG  G  G  GP G A
Sbjct: 871  SPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 920

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 43/107 (40%), Positives = 50/107 (46%), Gaps = 9/107 (8%)
 Frame = +2

Query: 239  GRMGKDGP---PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
            GR+G  GP   PGP+G LG+PG  G                    GD G  G  GV G A
Sbjct: 912  GRVGPPGPAGAPGPAGPLGEPGKEGPPGPR---------------GDPGSHGRVGVRGPA 956

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGN------IGPKGERGPKGV 532
            G  G PGD G  G DG  G  GPPGP G       +G  G+RG +G+
Sbjct: 957  GPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM 1003

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/103 (39%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  GP GP GK G+ G PGR                   G  G PG  G  G+ GL 
Sbjct: 249 GPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLE 308

Query: 419 GP------PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP      PG  G AG  GP G+ GP GP G  G +G  GP+G
Sbjct: 309 GPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQG 351

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 39/100 (39%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  G PG  G+LG  G PG+                   G +G PG+PG+ G AG  
Sbjct: 333 GPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPT 392

Query: 419 G---PPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G   P G  G  G  GP G  G PG  G IG  G  GPKG
Sbjct: 393 GARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGPKG 432

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 41/105 (39%), Positives = 49/105 (46%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233 EPGRMGKDGP---PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
           +PG  G+ GP   PGP G  G  G PG                   +G+ G PG+ G  G
Sbjct: 469 DPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTLGPPGPVGERGAPGNRGFPG 528

Query: 404 NAGLIGP---PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           + GL GP    G+ G  G+ GPKGSQG PG  G  G  G RG  G
Sbjct: 529 SDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTG 573

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 40/97 (41%), Positives = 44/97 (45%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G +G+ G PGP G +G PG  G                    G  G  G PGV G  G  
Sbjct: 807  GLLGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFA---GPQGSDGQPGVKGEPGEP 863

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  GDAGS G  G  GS GP GP G  G KG RG +G
Sbjct: 864  GQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 900

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 35/98 (35%), Positives = 42/98 (42%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG+ G  G PG  G +G  G PG +                + G  G  G  G  G  G 
Sbjct: 353 PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGP 412

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           +G PG  G+ G DG  G +GP G  G  GP G  GP G
Sbjct: 413 VGSPGLPGAIGTDGTPGPKGPTGSPGTSGPPGSAGPPG 450

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 40/98 (40%), Positives = 43/98 (43%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G  GPPGP+G LG+ G PG                  S G+ G  G  G AG  G  
Sbjct: 795  GLPGPLGPPGPAGLLGEKGEPG---PRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGSD 851

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G PG  G  G  G KG  G PGP G  G  G  GP GV
Sbjct: 852  GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV 889

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/101 (38%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLG---DPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
            G  G DG PG  G +G   D G PG A                + GDAG+ GDPG  G  
Sbjct: 1047 GPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI 1106

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G +G  G  G  G  GP+G +G  G  G+ G KG RG  G+
Sbjct: 1107 GHLGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGL 1147

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 40/105 (38%), Positives = 42/105 (40%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPG------FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            EPG+ G  G PGP G  G PG       PG                  S G  G PG  G
Sbjct: 862  EPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 921

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G AG +G PG  G  G  G  GS G  G  G  GP G  G KG
Sbjct: 922  APGPAGPLGEPGKEGPPGPRGDPGSHGRVGVRGPAGPPGGPGDKG 966

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 39/104 (37%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN--- 406
            PG+ G+ G PG  G  G PG  G                  S G  GEPG  G AGN   
Sbjct: 995  PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1054

Query: 407  ---AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                G +G  GD G  G  G  GSQG PG  G +G  G+ G +G
Sbjct: 1055 PGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG 1098

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 39/101 (38%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGK---LGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
           PG  G+ GP GP G    LG  G PG                    G  G  G PG  G 
Sbjct: 317 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAP---------GQRGAHGMPGKPGP 367

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G +G PG +G  GN G KG  GP G  G  GP+G+RG  G
Sbjct: 368 MGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETG 408

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 38/98 (38%), Positives = 39/98 (39%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G  GP GP G  G  G  G                    G  GEPGDPG  G  G 
Sbjct: 212 PGSVGPVGPRGPQGLQGQQGGAGPT------------------GPPGEPGDPGPMGPIGS 253

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP G  G  G DG  G  G PG  G  G  G RG  G
Sbjct: 254 RGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPG 291

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 38/102 (37%), Positives = 42/102 (41%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPGR G  G  G +G  G  GFPG                    G+ G PG  G AG  G
Sbjct: 268 EPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTG 327

Query: 413 ---LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
               +GP G  G  G  G  G QG PG  G  G  G+ GP G
Sbjct: 328 PMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG 369

 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 35/99 (35%), Positives = 41/99 (41%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G  G PG  G  G PG PG                  + G  GE G  G  G  G 
Sbjct: 275 PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGP 334

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +GP G  G  G  GP+G+ G  G  G  G  G  GP G+
Sbjct: 335 LGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGI 373

 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 37/98 (37%), Positives = 44/98 (44%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  G PGP G  G+ G PGR                 ++G+ G+ GDPG AG    
Sbjct: 1034 PGSNGPVGEPGPEGPAGNDGTPGR---------------DGAVGERGDRGDPGPAGL--- 1075

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
               PG  G+ G  GP G+   PG  G  G  G RGP G
Sbjct: 1076 ---PGSQGAPGTPGPVGA---PGDAGQRGDPGSRGPIG 1107

 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 41/129 (31%), Positives = 48/129 (37%), Gaps = 30/129 (23%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGR---------------------------AXXXXXXX 331
           E G  G+ GP GP G  G+PG PG+                                   
Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204

Query: 332 XXXXXXXXXSIGDAGEPGDPGV---AGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIG 502
                    S+G  G  G  G+    G AG  GPPG+ G  G  GP GS+GP GP G  G
Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPG 264

Query: 503 PKGERGPKG 529
             GE G  G
Sbjct: 265 EDGEPGRNG 273

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 37/109 (33%), Positives = 43/109 (39%), Gaps = 12/109 (11%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G  GP G++G PG  G A                ++G  G  G PG  G  G  
Sbjct: 300 GHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG---------AMGPLGPRGMPGERGRLGPQ 350

Query: 419 GPPGDAGSAGNDGPKGSQGP------------PGPTGNIGPKGERGPKG 529
           G PG  G+ G  G  G  GP            PG  G  GP G RGP+G
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEG 399

 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 40/133 (30%), Positives = 46/133 (34%), Gaps = 36/133 (27%)
 Frame = +2

Query: 239 GRMGKDGPP---GPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG----- 394
           GR G  GPP   GP G+ G  G PG                  + G  G P  PG     
Sbjct: 129 GRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188

Query: 395 ----------------------VAGNAGLIGP------PGDAGSAGNDGPKGSQGPPGPT 490
                                 + G+ G +GP       G  G AG  GP G  G PGP 
Sbjct: 189 RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPM 248

Query: 491 GNIGPKGERGPKG 529
           G IG +G  GP G
Sbjct: 249 GPIGSRGPEGPPG 261

 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 37/119 (31%), Positives = 43/119 (36%), Gaps = 18/119 (15%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS------------IGDAG 376
           EPG  G+ G PGP G    PG  G +                             +G  G
Sbjct: 163 EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222

Query: 377 EPGDPGVAGNAGLIGPPGDAGSAG------NDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G  G  G AG  GPPG+ G  G      + GP+G  G PG  G  G  G  G  G A
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 26/57 (45%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
 Frame = +2

Query: 365 GDAGEPGDPG-VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G  G+ G+PG V    G+ G PG AG  G+ GP+G +GP G  G  GP+G  G  GV
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGV 166

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 27/59 (45%), Positives = 28/59 (47%), Gaps = 4/59 (6%)
 Frame = +2

Query: 365 GDAGEPG----DPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  GEPG      G+ G  G  GPPG  G  G  GPKG  GP GP G  G  G  G  G
Sbjct: 113 GQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPG 171

 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 24/57 (42%), Positives = 26/57 (45%)
 Frame = +2

Query: 365 GDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G AG PG  G  G  G  G PG  G  G DG  G  G PG  G  G     GP G++
Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 32/99 (32%), Positives = 37/99 (37%), Gaps = 4/99 (4%)
 Frame = +2

Query: 239 GRMGKDGPPG----PSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
           GR G+ G PG     +G  G PG  G                    G  G  G+ G  G 
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGRPGPAGPP------------------GSQGPRGERGPKGR 151

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGP 523
            G  GP G  G  G  G  G+ GPPG   + GP G   P
Sbjct: 152 PGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190
>sp|P12107|CA1B_HUMAN Collagen alpha 1(XI) chain precursor
          Length = 1806

 Score =  160 bits (405), Expect = 9e-39
 Identities = 124/419 (29%), Positives = 179/419 (42%), Gaps = 10/419 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+DGPPGP G  G PG  G                    G+ GE GD G+ G  G 
Sbjct: 1422 PGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1481

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G  GD G  G  GP G  GPPG  G  GPKG +G  G A                    
Sbjct: 1482 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGPPGPPGE 1541

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                        I   ++T    E  Q D       + +D +D 
Sbjct: 1542 VIQPLP----------------------ILSSKKTRRHTEGMQADADD----NILDYSDG 1575

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
             E+IF +L  L   ++++  P G++T PAR+C D+Q  + +  +G Y+IDPN G   D+ 
Sbjct: 1576 MEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSF 1635

Query: 956  YVFCNFEK-LETCIEPEVSN--YKKTSYMKSH-SSWFSILASLNKQVSY------KIPKE 1105
             V+CNF    ETCI P+  +   + +S+ K    SWFS      K +SY       I   
Sbjct: 1636 KVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEF-KRGKLLSYLDVEGNSINMV 1694

Query: 1106 QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDDDLF 1285
            Q+ FL+L + S  QNFT  C       D S      Y+ +L+ LG +++ ++ +N+  + 
Sbjct: 1695 QMTFLKLLTASARQNFTYHCHQSAAWYDVS---SGSYDKALRFLGSNDEEMSYDNNPFI- 1750

Query: 1286 QYQIIEDNCKGKSSSGRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVCFSG 1462
              + + D C  +    + VI++   +  ++PI D          Q K G E+GPVCF G
Sbjct: 1751 --KTLYDGCTSRKGYEKTVIEINTPKIDQVPIVDVMISDFGDQNQ-KFGFEVGPVCFLG 1806

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 45/102 (44%), Positives = 52/102 (50%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLG---DPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
           +PG  G DGPPGP G +G   +PG PG+                   G+ G  G PG+AG
Sbjct: 665 QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 724

Query: 404 NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G  GPPG  G  G  G KG+ GPPGP G IG  G RG KG
Sbjct: 725 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766

 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 44/100 (44%), Positives = 49/100 (49%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGE---PGDPGVAGNA 409
            G  G++GPPGP G  G  G PG A                  GD G    PG PG  G  
Sbjct: 1141 GGKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GL GPPG+ G  G+ GP G  GPPGP G  GP G  GP+G
Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG 1240

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 43/103 (41%), Positives = 48/103 (46%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLG------DPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVA 400
            G  G DGP GP G +G      + G PG A                  G+ GE G PG A
Sbjct: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290

Query: 401  GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G  GPPGD G  GN GP G  G PGP G +GP G+ G  G
Sbjct: 1291 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGELGPAGQDGVGG 1333

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 43/103 (41%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G+ GPPGPSG+ G PG PG+                 + G+AG  G PG  G  G
Sbjct: 1337 EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1396

Query: 413  LIGP---PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
              GP   PG  G  G  GP G QG PG  G  GP G  GP G+
Sbjct: 1397 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1439

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 46/110 (41%), Positives = 49/110 (44%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG------- 394
            PG  G +GP GP G +G PG  G A                  G AGE G PG       
Sbjct: 1041 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLRGRPGPQGPPGPAGEKGAPGEKGPQGP 1100

Query: 395  -----VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                 V G  GL GP G AGS G DG KG  G PG  G+ G KGE GP G
Sbjct: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGGKGENGPPG 1150

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 41/99 (41%), Positives = 48/99 (48%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           + G  G+ GP GP G  GD G  G                    G+ G  G PG AG  G
Sbjct: 611 DKGHRGERGPQGPPGPPGDDGMRGED------------------GEIGPRGLPGEAGPRG 652

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           L+GP G  G+ G  G  G  GPPGP GN+GP+GE GP G
Sbjct: 653 LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPG 691

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 42/98 (42%), Positives = 47/98 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G DG  G  G++G  G PG A                  G AG  G PG  GN G 
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP 683

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  GN GP+G  GP GP   IGP GE+GP+G
Sbjct: 684 QGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQG 718

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 44/100 (44%), Positives = 48/100 (48%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  G PGP G  GDPG PG                    GD GE GDPG  G    
Sbjct: 1299 PGDDGPKGNPGPVGFPGDPGPPGELGPAGQDGVG---------GDKGEDGDPGQPG---- 1345

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
              PPG +G AG  GP G +GPPG  G  G +GE+G KG A
Sbjct: 1346 --PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383

 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 43/109 (39%), Positives = 51/109 (46%), Gaps = 12/109 (11%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G DGP G  G +G PG PG                    GD G+PG PG +G AG  
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGELGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356

Query: 419  GPPGD------AGSAGNDGPKGS------QGPPGPTGNIGPKGERGPKG 529
            GPPG       AG+ G  G KG+      +GPPG TG +GP+G  G  G
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 39/100 (39%), Positives = 44/100 (44%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  GK+G  G  G LG PG  G                    G  GE G+ G  G  G 
Sbjct: 732  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 791

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            +G  GD G  G  GP+G  GP GP G  GP G+ GP G A
Sbjct: 792  MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 831

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 40/97 (41%), Positives = 48/97 (49%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPGP+GK G  G PG                  + G  G PG+PG  G+ G  
Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPG------------------ADGGRGMPGEPGAKGDRGFD 603

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G PG  G  G+ G +G QGPPGP G+ G +GE G  G
Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIG 640

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 43/106 (40%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGD---------PGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDP 391
            GR G  G PGPSG+ G+         PG+PGR                 S G  G PG  
Sbjct: 817  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGR------------QGPKGSTGFPGFPGAN 864

Query: 392  GVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G  G+ G PG  G  G  GP+GS+G  GPTG  GPKG  G  G
Sbjct: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 41/102 (40%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            + G  G  GPPGP G +G PG  G                  S G+ GE G PG  G+ G
Sbjct: 740  QSGEKGALGPPGPQGPIGYPGPRG------VKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793

Query: 413  LIGPPGDAGSAG---NDGPKGSQGPPGPTGNIGPKGERGPKG 529
            L G  G+ G  G    DGP+G +G  GPTG+ GP G+ G KG
Sbjct: 794  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG 835

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 47/125 (37%), Positives = 54/125 (43%), Gaps = 24/125 (19%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDA------GEPGDPG 394
            E G +G+ G PGP G  G+ G PG A                  G A      GE G PG
Sbjct: 977  ETGPIGERGYPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036

Query: 395  VAGNAGL------------IGPPGDAGSAGNDGP------KGSQGPPGPTGNIGPKGERG 520
              G  GL            +G PG+ GSAG  GP       G QGPPGP G  G  GE+G
Sbjct: 1037 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLRGRPGPQGPPGPAGEKGAPGEKG 1096

Query: 521  PKGVA 535
            P+G A
Sbjct: 1097 PQGPA 1101

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 40/98 (40%), Positives = 48/98 (48%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG+ G  GP GP+GK G  G  G                   +G+ G PG  G  G  G 
Sbjct: 1389 PGKTGPVGPQGPAGKPGPEGLRG---------------IPGPVGEQGLPGAAGQDGPPGP 1433

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            +GPPG  G  G+ G KG +G PG  G IGP GE+G KG
Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 41/107 (38%), Positives = 45/107 (42%), Gaps = 6/107 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGE------PGDPG 394
            + G  G  GPPGP G  G PG PG                    G  G        G PG
Sbjct: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1243

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
              G+ G +G  G+ G AGN GP G  G  GP G  G KGE GP G A
Sbjct: 1244 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290

 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 44/118 (37%), Positives = 49/118 (41%), Gaps = 18/118 (15%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  GP G  G+ G+ G PG A                  G  G PGD G  GN G 
Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPP---------------GAKGPPGDDGPKGNPGP 1310

Query: 416  IGPPGD---------------AGSAGNDGPKGSQGPPGPTGNI---GPKGERGPKGVA 535
            +G PGD                G  G DG  G  GPPGP+G     GP G+RGP G A
Sbjct: 1311 VGFPGDPGPPGELGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 40/101 (39%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS---IGDAGEPGDPGVAGN 406
            PG  GKDG PG  G+ G+ GF G+                     IG+ G PG PG  G 
Sbjct: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGYPGPPGPPGE 995

Query: 407  AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GL G  G  G+ G+ GP+G  G  GP G  G  GERG  G
Sbjct: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 44/122 (36%), Positives = 48/122 (39%), Gaps = 21/122 (17%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  GK GPPGP G +G  G  G                    G  GE G PG AG  G
Sbjct: 953  ETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGYPGPP------GPPGEQGLPGAAGKEG 1006

Query: 413  LIGPPGDAGSAGNDGP---------------------KGSQGPPGPTGNIGPKGERGPKG 529
              G PG  G +G DGP                     KG +GP GP G +G  GERG  G
Sbjct: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066

Query: 530  VA 535
             A
Sbjct: 1067 TA 1068

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 41/102 (40%), Positives = 47/102 (46%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN---A 409
            G  G  GPPGP GK G PG PG+                   G  G PG  GV G     
Sbjct: 928  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQ------------GKTGPPGPGGVVGPQGPT 975

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G  GP G+ G  G  GP G QG PG  G  G KG+ GP+G++
Sbjct: 976  GETGPIGERGYPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 43/105 (40%), Positives = 45/105 (42%), Gaps = 6/105 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  GKDGP G  G  G+ G PG                   +G  GE G  G AG  GL 
Sbjct: 1015 GISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLR 1074

Query: 419  G------PPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G      PPG AG  G  G KG QGP G  G  GP G  GP G A
Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1119

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 41/103 (39%), Positives = 46/103 (44%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            GR G  GPPGP+G+ G PG  G                    G AG  G PG  G+ G I
Sbjct: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP---GPAGPAGSPGEDGDKGEI 1131

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGP------KGERGPKG 529
            G PG  GS G  G  G  GPPG  G +G        GE GP+G
Sbjct: 1132 GEPGQKGSKGGKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1174

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 38/102 (37%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G+DGP GP G+ G  G PG +                  G  G  G  G  G  G  
Sbjct: 805  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 864

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIG---PKGERGPKGVA 535
            G  G  G AG  GP+G +GP GP G+ G   P G+ GPKG +
Sbjct: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 38/97 (39%), Positives = 40/97 (41%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G  G PGP G  G  G PG                    G  G PG  G+ G+ G  
Sbjct: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G  G  G  GP G  GP GPTG  GP GERG  G
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGYPG 988

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 41/107 (38%), Positives = 44/107 (41%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGR---------AXXXXXXXXXXXXXXXXSIGDAGEPGD 388
            PG  G  G  GP G  G PGFPG          A                S G  G  G 
Sbjct: 840  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 899

Query: 389  PGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            PG  G +G  GPPG  G  G  GP+G  G PGP G  GP G+ G  G
Sbjct: 900  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 946

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 38/100 (38%), Positives = 44/100 (44%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           +  R+   GPPGP G  G PG  G                  S G  GE GDPG  G  G
Sbjct: 521 QQARIALRGPPGPMGLTGRPGPVG---------------GPGSSGAKGESGDPGPQGPRG 565

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           + GPPG  G  G  G  G+ G  G  G  G KG+RG  G+
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL 605

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 40/100 (40%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239  GRMGKDGP---PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
            GR G  GP   PGP+G  G PG  G                  S G  GE G PG  G  
Sbjct: 1102 GRDGVQGPVGLPGPAGPAGSPGEDG------DKGEIGEPGQKGSKGGKGENGPPGPPGLQ 1155

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G +G PG AG  G  GP+G QG  G  G+ G +G  GP G
Sbjct: 1156 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 37/105 (35%), Positives = 43/105 (40%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGK------LGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            +PG  G+ GP GP G        G PG  G +                  G  G PG  G
Sbjct: 875  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 934

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G  G  G PG  G  G  G +G  GPPGP G +GP+G  G  G
Sbjct: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG 979

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 35/99 (35%), Positives = 43/99 (43%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G+ GP GP+G+ G  G  G                   IG+ G+ G  G  G  G
Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGGKGENG 1147

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPPG  G  G  G  G  G PGP G  G  G++G +G
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1186

 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 38/110 (34%), Positives = 44/110 (40%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKL--------GD----PGFPGRAXXXXXXXXXXXXXXXXSIGDAGE 379
           PG  G DG PGP G +        GD    P    +                   G  G 
Sbjct: 477 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 536

Query: 380 PGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G  G  G++G  G  GP+G QGPPGPTG  G +G  G  G
Sbjct: 537 TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 586

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 40/100 (40%), Positives = 44/100 (44%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA--- 409
            G  G+DG PG  G +G  G  G                    G AG  GDPG +G A   
Sbjct: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK---GRAGPTGDPGPSGQAGEK 834

Query: 410  GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G +G PG  G  G  GPKGS G PG  G  G KG RG  G
Sbjct: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 37/97 (38%), Positives = 40/97 (41%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G  G  G  G+ G+ GFPG                   IG  GE G  G  G AG  
Sbjct: 766  GADGVRGLKGSKGEKGEDGFPG---FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 822

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG +G AG  G  G  G PG  G  GPKG  G  G
Sbjct: 823  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPG 859

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 44/128 (34%), Positives = 50/128 (39%), Gaps = 29/128 (22%)
 Frame = +2

Query: 233 EPGRM--GKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
           EPG +  G  GP GP+G +G PG  G                    GD G PG PG+ G 
Sbjct: 435 EPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------------GDRGPPGRPGLPGA 482

Query: 407 AGLIGPPGDA-------GSAGNDGPKGS-----------------QGPPGP---TGNIGP 505
            GL GPPG         G  G+ GP  S                 +GPPGP   TG  GP
Sbjct: 483 DGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP 542

Query: 506 KGERGPKG 529
            G  G  G
Sbjct: 543 VGGPGSSG 550

 Score = 55.1 bits (131), Expect = 6e-07
 Identities = 33/95 (34%), Positives = 43/95 (45%), Gaps = 1/95 (1%)
 Frame = +2

Query: 251 KDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI-GPP 427
           +D P  P  +   PG P                   + G+ G+ G+P V     L+ GPP
Sbjct: 390 EDKPTSPPNEEFGPGVPAETDITETSINGHG-----AYGEKGQKGEPAVVEPGMLVEGPP 444

Query: 428 GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G AG AG  GP G QGP GP G+ G +G  G  G+
Sbjct: 445 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
>sp|Q01149|CO1A2_MOUSE Collagen alpha 2(I) chain precursor
          Length = 1372

 Score =  158 bits (400), Expect = 4e-38
 Identities = 121/419 (28%), Positives = 177/419 (42%), Gaps = 12/419 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  GP G  G  G+PG  G                    GD GEPGD G  G  GL
Sbjct: 969  PGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDKGHRGLPGL 1028

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G  G  G  G  G  G QG PGP G  GP+G  GP G                      
Sbjct: 1029 KGYSGLQGLPGLAGLHGDQGAPGPVGPAGPRGPAGPSGPVGKDGRSGQPGPVGPAGVRGS 1088

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                     +   F       E + ++ D+P+++   S+ P D 
Sbjct: 1089 QGSQGPAGPPGPPGPPGPPGVSGGGYDFGF-------EGDFYRADQPRSQP--SLRPKDY 1139

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
            + D    L  L+  ++ L  P GS+  PAR+C D++  +   ++  Y+IDPN G   DAI
Sbjct: 1140 EVDA--TLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWNSDYYWIDPNQGCTMDAI 1197

Query: 956  YVFCNFEKLETCIEPE-VSNYKKTSYMKSHSS---WFSILASLNKQVSYKI----PKE-- 1105
             V+C+F   ETCI+ + V+   K SY ++ ++   W     +   Q  Y +     KE  
Sbjct: 1198 KVYCDFSTGETCIQAQPVNTPAKNSYSRAQANKHVWLGETINGGSQFEYNVEGVSSKEMA 1257

Query: 1106 -QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDDDL 1282
             QL F++L +   SQN T  C N    S   +++E    N   LL   N +  V   +  
Sbjct: 1258 TQLAFMRLLANRASQNITYHCKN----SIAYLDEETGSLNKAVLLQGSNDVELVAEGNSR 1313

Query: 1283 FQYQIIEDNCKGKSSS-GRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVCF 1456
            F Y ++ D C  K++  G+ +I+ + ++P RLP  D     +  + Q +  VE+GPVCF
Sbjct: 1314 FTYSVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDIGGADQ-EFRVEVGPVCF 1371

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 43/100 (43%), Positives = 49/100 (49%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGPSG  G PG PG A                  G+ G  G PG  G  G 
Sbjct: 795  PGAAGRTGPPGPSGIAGPPGPPGAAGKEGIRGPRGDQGPVGRTGETGASGPPGFVGEKGP 854

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G PG AG+ G  GP+G  G PG  G  G +GERG  G+A
Sbjct: 855  SGEPGTAGAPGTAGPQGLLGAPGILGLPGSRGERGLPGIA 894

 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 45/109 (41%), Positives = 53/109 (48%), Gaps = 9/109 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS---------IGDAGEPG 385
           EPG +G  GPPGPSG+ G  G PG A                S          G  G PG
Sbjct: 368 EPGSVGAQGPPGPSGEEGKRGSPGEAGSAGPAGPPGLRGSPGSRGLPGADGRAGVMGPPG 427

Query: 386 DPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           + G  G AG+ GP GDAG  G  G  G +G PG  GN+GP G+ GP G+
Sbjct: 428 NRGSTGPAGIRGPNGDAGRPGEPGLMGPRGLPGSPGNVGPSGKEGPVGL 476

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 42/97 (43%), Positives = 45/97 (46%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G +GPPGP G  GD G PG                    G AG PG PG AG  G+ 
Sbjct: 769  GPSGPNGPPGPVGSRGDGGPPGMTGFPGAAGRTGPPGPS---GIAGPPGPPGAAGKEGIR 825

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP GD G  G  G  G+ GPPG  G  GP GE G  G
Sbjct: 826  GPRGDQGPVGRTGETGASGPPGFVGEKGPSGEPGTAG 862

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 43/105 (40%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPG---PSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            EPG +G  GPPG   P G +G PG    PG A                  G  GE G PG
Sbjct: 899  EPGPLGISGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGSDGPPGRDGQPGHKGERGYPG 958

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G  G  G PG  GS G  G  G++G PGP G++GP G  GP+G
Sbjct: 959  SIGPTGAAGAPGPHGSVGPAGKHGNRGEPGPAGSVGPVGAVGPRG 1003

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 43/98 (43%), Positives = 47/98 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG MG  GP GP G +G PG  G                    G AGEPG+PG  G AG 
Sbjct: 96  PGPMGLMGPRGPPGAVGAPGPQGFQ------------------GPAGEPGEPGQTGPAGP 137

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP G  G AG DG  G  G PG  G +GP+G RG  G
Sbjct: 138 RGPAGSPGKAGEDGHPGKPGRPGERGVVGPQGARGFPG 175

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/106 (39%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPG------FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG  G++G PG +G  G PG       PG A                 IG AG PG PG
Sbjct: 206 EPGAPGENGTPGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 265

Query: 395 VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G +GP G+ G AG  GP+G  G PG +G +GP G  G  G+
Sbjct: 266 APGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGPVGPPGNPGTNGL 311

 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 42/97 (43%), Positives = 50/97 (51%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           GR G  GP GP G+ G+ GFPG                    G +G+PG PG  G+ GL 
Sbjct: 481 GRPGPIGPAGPRGEAGNIGFPGPK------------------GPSGDPGKPGERGHPGLA 522

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G     G+ G DG  G+QGPPGP G  G KGE+GP G
Sbjct: 523 GA---RGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAG 556

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 38/97 (39%), Positives = 45/97 (46%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPGP G  G  G  G A                + G+ G+PG+ G+ G  GL 
Sbjct: 532 GNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPSG---TTGEVGKPGERGLPGEFGLP 588

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  G  G  G  G+ GP GP G+ GP G  GP G
Sbjct: 589 GPAGPRGERGTPGESGAAGPSGPIGSRGPSGAPGPDG 625

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 45/108 (41%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G  GP G LG PG  G                    G  GEPG  G++G  G
Sbjct: 857  EPGTAGAPGTAGPQGLLGAPGILGLPGSRGERGLPGIA------GALGEPGPLGISGPPG 910

Query: 413  LIGPPGDAGS---------AGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPPG  GS         AG DG  GS GPPG  G  G KGERG  G
Sbjct: 911  ARGPPGAVGSPGVNGAPGEAGRDGNPGSDGPPGRDGQPGHKGERGYPG 958

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 38/98 (38%), Positives = 44/98 (44%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G  GP G SG  G+ G  G +                  G+ G  G  G AG AG 
Sbjct: 684 PGAVGAPGPAGASGDRGEAGAAGPSGPAGPRGSPGER------GEVGPAGPNGFAGPAGA 737

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G  GPKG  G  GPTG++G  G  GP G
Sbjct: 738 AGQPGAKGEKGTKGPKGENGIVGPTGSVGAAGPSGPNG 775

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 37/99 (37%), Positives = 42/99 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GP GP+G  G PG  G                    G  GE G  G  G  G++
Sbjct: 700 GEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGEKGTKGPKGENGIV 759

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           GP G  G+AG  GP G  GP G  G+ GP G  G  G A
Sbjct: 760 GPTGSVGAAGPSGPNGPPGPVGSRGDGGPPGMTGFPGAA 798

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 39/98 (39%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP GP G+ G PG  G A                S G +G PG  G  G AG 
Sbjct: 582 PGEFGLPGPAGPRGERGTPGESGAAGPSGPIG---------SRGPSGAPGPDGNKGEAGA 632

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           +G PG AG++G  G  G +G  G  G  G KGE G +G
Sbjct: 633 VGAPGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRG 670

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  GP GP G  G PGFPG                    G  GE G PG++G    +
Sbjct: 244 GSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGP---V 300

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKGVA 535
           GPPG+ G+ G  G KG+ G PG  G     GP+G  GP G A
Sbjct: 301 GPPGNPGTNGLTGAKGATGLPGVAGAPGLPGPRGIPGPAGAA 342

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 37/99 (37%), Positives = 43/99 (43%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PG +G  G  G PG                    GD G  G  G  G  G +
Sbjct: 628 GEAGAVGAPGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRGDTGNTGRDGARGIPGAV 687

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G PG AG++G+ G  G+ GP GP G  G  GERG  G A
Sbjct: 688 GAPGPAGASGDRGEAGAAGPSGPAGPRGSPGERGEVGPA 726

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 46/119 (38%), Positives = 50/119 (42%), Gaps = 21/119 (17%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG---VAGN 406
           PG  G  GP G  G  G PG PG                  + G  GEPG PG     G 
Sbjct: 159 PGERGVVGPQGARGFPGTPGLPGFKGVKGHSGMDGLKGQPGAQGVKGEPGAPGENGTPGQ 218

Query: 407 AGL---------IGPPGDAGSAGND---------GPKGSQGPPGPTGNIGPKGERGPKG 529
           AG          +G PG AG+ G+D         GP GS GPPG  G  GPKGE GP G
Sbjct: 219 AGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVG 277

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 44/111 (39%), Positives = 51/111 (45%), Gaps = 12/111 (10%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG-- 412
           G  G+ G PG SG +G PG PG                  + G  G  G PG AG AG  
Sbjct: 286 GPRGEVGLPGLSGPVGPPGNPGTNGLTGAKGATGLPGVAGAPGLPGPRGIPGPAGAAGAT 345

Query: 413 ----LIGPPGDAGSAGNDGPKG------SQGPPGPTGNIGPKGERGPKGVA 535
               L+G PG AGS G  G KG      +QGPPGP+G  G +G  G  G A
Sbjct: 346 GARGLVGEPGPAGSKGESGNKGEPGSVGAQGPPGPSGEEGKRGSPGEAGSA 396

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 38/100 (38%), Positives = 43/100 (43%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G+ G  G PG                    G  G PG  G  G AG 
Sbjct: 636 PGSAGASGPGGLPGERGAAGIPGGKGEKGETGLRGDTGNTGRDGARGIPGAVGAPGPAGA 695

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G  G+AG+AG  GP G +G PG  G +GP G  G  G A
Sbjct: 696 SGDRGEAGAAGPSGPAGPRGSPGERGEVGPAGPNGFAGPA 735

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 39/97 (40%), Positives = 41/97 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           GR G DGP GP G  G PG PG                     D G    PG  G  G  
Sbjct: 51  GRDGVDGPMGPPGPPGSPGPPGSPAPPGLTGNFAA-----QYSDKGVSSGPGPMGLMGPR 105

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GPPG  G+ G  G +G  G PG  G  GP G RGP G
Sbjct: 106 GPPGAVGAPGPQGFQGPAGEPGEPGQTGPAGPRGPAG 142

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/97 (41%), Positives = 41/97 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PGP G  GDPG PG                    G AG  G PG  GN G  
Sbjct: 493 GEAGNIGFPGPKGPSGDPGKPGERGHP---------------GLAGARGAPGPDGNNGAQ 537

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GPPG  G  G  G +G  GPPG  G  GP G  G  G
Sbjct: 538 GPPGPQGVQGGKGEQGPAGPPGFQGLPGPSGTTGEVG 574

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/104 (37%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ G  GP G+ G  G  G                  S GD G PG  G  G AG
Sbjct: 740  QPGAKGEKGTKGPKGENGIVGPTGSVGAAGPSGPNGPPGPVGSRGDGGPPGMTGFPGAAG 799

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPG---PTGNIGPKGERGPKGVA 535
              GPPG +G AG  GP G+ G  G   P G+ GP G  G  G +
Sbjct: 800  RTGPPGPSGIAGPPGPPGAAGKEGIRGPRGDQGPVGRTGETGAS 843

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 40/107 (37%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ G PG +G LG+PG  G +                S G  G PG+ G  GN G 
Sbjct: 882  PGSRGERGLPGIAGALGEPGPLGISGPPGARGPPGAVG---SPGVNGAPGEAGRDGNPGS 938

Query: 416  IGPP---------GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GPP         G+ G  G+ GP G+ G PGP G++GP G+ G +G
Sbjct: 939  DGPPGRDGQPGHKGERGYPGSIGPTGAAGAPGPHGSVGPAGKHGNRG 985

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 37/101 (36%), Positives = 44/101 (43%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           +PG  G  G PG  G+ G PG  G                  + G  G  G  G AG  G
Sbjct: 197 QPGAQGVKGEPGAPGENGTPGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIG 256

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             GPPG  G+ G  G  G  G PGP G  GP+GE G  G++
Sbjct: 257 SAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEVGLPGLS 297

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 43/104 (41%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV------ 397
            PG  G+DG PG  G  G  G PG                  SIG  G  G PG       
Sbjct: 927  PGEAGRDGNPGSDGPPGRDGQPGHKGERGYPG---------SIGPTGAAGAPGPHGSVGP 977

Query: 398  AGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            AG  G  G PG AGS G  G  G +GP GP G  G KGE G KG
Sbjct: 978  AGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGDKG 1021

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 36/99 (36%), Positives = 46/99 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G  GP G  G  G+PG PG+                   G+ G PG PG  G  G+
Sbjct: 108 PGAVGAPGPQGFQGPAGEPGEPGQTGPAGPRGPAGSPG---KAGEDGHPGKPGRPGERGV 164

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +GP G  G  G  G  G +G  G +G  G KG+ G +GV
Sbjct: 165 VGPQGARGFPGTPGLPGFKGVKGHSGMDGLKGQPGAQGV 203

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 38/99 (38%), Positives = 41/99 (41%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G  GP GP G  G+ G  G A                  G AG  G PG  G  G
Sbjct: 701 EAGAAGPSGPAGPRGSPGERGEVGPAGPNGF------------AGPAGAAGQPGAKGEKG 748

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GP G+ G  G  G  G+ GP GP G  GP G RG  G
Sbjct: 749 TKGPKGENGIVGPTGSVGAAGPSGPNGPPGPVGSRGDGG 787

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 38/101 (37%), Positives = 43/101 (42%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           +PGR G+ G  GP G  G PG PG                    G  G  G+PG  G  G
Sbjct: 155 KPGRPGERGVVGPQGARGFPGTPGLPGFKGVKGHSGMDGLKGQPGAQGVKGEPGAPGENG 214

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
               PG AG+ G  G +G  G PGP G  G  G  GP G A
Sbjct: 215 T---PGQAGARGLPGERGRVGAPGPAGARGSDGSVGPVGPA 252

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 37/98 (37%), Positives = 42/98 (42%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GP GP+G  G  G  G+                   G  G  G  G AG +G 
Sbjct: 717  PGERGEVGPAGPNGFAGPAGAAGQPGAKGEKGTKGPKGEN---GIVGPTGSVGAAGPSGP 773

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GPPG  GS G+ GP G  G PG  G  GP G  G  G
Sbjct: 774  NGPPGPVGSRGDGGPPGMTGFPGAAGRTGPPGPSGIAG 811

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 39/98 (39%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G +G++G PG                       G  GE G PG AG  G 
Sbjct: 558 PGFQGLPGPSGTTGEVGKPG---------------------ERGLPGEFGLPGPAGPRGE 596

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG++G+AG  GP GS+GP G  G  G KGE G  G
Sbjct: 597 RGTPGESGAAGPSGPIGSRGPSGAPGPDGNKGEAGAVG 634

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 37/99 (37%), Positives = 41/99 (41%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PGPSG  G+ G PG                    G  GE G  G +G  G  
Sbjct: 556 GPPGFQGLPGPSGTTGEVGKPGERGLPGEFGLPGPAGPRGERGTPGESGAAGPSGPIGSR 615

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           GP G  G  GN G  G+ G PG  G  GP G  G +G A
Sbjct: 616 GPSGAPGPDGNKGEAGAVGAPGSAGASGPGGLPGERGAA 654

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 43/111 (38%), Positives = 44/111 (39%), Gaps = 12/111 (10%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PG  G  G  G PG A                  GD G PG  G AG  G
Sbjct: 1016 EPGDKGHRGLPGLKGYSGLQGLPGLAGLH---------------GDQGAPGPVGPAGPRG 1060

Query: 413  LIGP------------PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GP            PG  G AG  G +GSQGP GP G  GP G  G  G
Sbjct: 1061 PAGPSGPVGKDGRSGQPGPVGPAGVRGSQGSQGPAGPPGPPGPPGPPGVSG 1111

 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 36/99 (36%), Positives = 40/99 (40%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG  G+ GP GP G  G PG  G                    G  G PG+ GV G  G
Sbjct: 125 EPGEPGQTGPAGPRGPAGSPGKAGEDGHP---------------GKPGRPGERGVVGPQG 169

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G PG  G  G  G KG  G  G  G  G +G +G  G
Sbjct: 170 ARGFPGTPGLPGFKGVKGHSGMDGLKGQPGAQGVKGEPG 208

 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 27/68 (39%), Positives = 31/68 (45%), Gaps = 13/68 (19%)
 Frame = +2

Query: 365 GDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNI-------------GP 505
           G  G+ G  G  G  G+ GP G  G  G+ GP GS  PPG TGN              GP
Sbjct: 39  GPRGQRGPAGPRGRDGVDGPMGPPGPPGSPGPPGSPAPPGLTGNFAAQYSDKGVSSGPGP 98

Query: 506 KGERGPKG 529
            G  GP+G
Sbjct: 99  MGLMGPRG 106

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 22/47 (46%), Positives = 25/47 (53%)
 Frame = +2

Query: 392 GVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G  G+ G  G  G AG  G DG  G  GPPGP G+ GP G   P G+
Sbjct: 33  GPTGDRGPRGQRGPAGPRGRDGVDGPMGPPGPPGSPGPPGSPAPPGL 79

 Score = 42.4 bits (98), Expect = 0.004
 Identities = 22/49 (44%), Positives = 23/49 (46%)
 Frame = +2

Query: 374 GEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERG 520
           G  GD G  G  G  GP G  G  G  GP G  G PGP G+  P G  G
Sbjct: 33  GPTGDRGPRGQRGPAGPRGRDGVDGPMGPPGPPGSPGPPGSPAPPGLTG 81
>sp|P02458|CO2A1_HUMAN Collagen alpha 1(II) chain precursor [Contains: Chondrocalcin]
          Length = 1418

 Score =  157 bits (396), Expect = 1e-37
 Identities = 120/432 (27%), Positives = 173/432 (40%), Gaps = 25/432 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGR------AXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
            PG  G  GP GP+GK GD G  G       +                  G+AGEPG+ G+
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1060

Query: 398  AGNAG------LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXX 559
             G+ G      L GPPG +G  G  GP G  GP GP G +GP G+ G  G+         
Sbjct: 1061 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120

Query: 560  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQ 739
                                               + F  +  R++  D  +  + D+  
Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDM----SAFAGLGpreKGPDPLQYMRADQAA 1176

Query: 740  AEQKSSIDPNDEDEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYY 919
               +        D ++   L  L+  ++++  P GS+  PAR+C D++  +    +G Y+
Sbjct: 1177 GGLRQ------HDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYW 1230

Query: 920  IDPNGGHWKDAIYVFCNFEKLETCIEPEVSNYKKTSYMKSHSS-----WFSILASLNKQV 1084
            IDPN G   DA+ VFCN E  ETC+ P  +N  K ++  S S      WF    +     
Sbjct: 1231 IDPNQGCTLDAMKVFCNMETGETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHF 1290

Query: 1085 SY-------KIPKEQLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGD 1243
            SY            Q+ FL+L S   SQN T  C N     D +     K      L+  
Sbjct: 1291 SYGDDNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKK----ALLIQG 1346

Query: 1244 DNQILTVNNDDDLFQYQIIEDNC-KGKSSSGRVVIKVELDRPRRLPIRDFNFKSLESSPQ 1420
             N +      +  F Y  ++D C K     G+ VI+    +  RLPI D     +   P+
Sbjct: 1347 SNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDI-GGPE 1405

Query: 1421 AKIGVEIGPVCF 1456
             + GV+IGPVCF
Sbjct: 1406 QEFGVDIGPVCF 1417

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 44/106 (41%), Positives = 52/106 (49%), Gaps = 6/106 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGR------AXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG +G  GPPG  G  G+ GFPG+                       + GD G PG+PG
Sbjct: 427 EPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG 486

Query: 395 VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           + G  GL G PGDAG  G  GP G+ G  G  G  GP+G RG  GV
Sbjct: 487 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 42/104 (40%), Positives = 53/104 (50%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPG +G  G PG PG +                  GD+G PG  G  G  G 
Sbjct: 830  PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR---------GDSGPPGRAGEPGLQGP 880

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPK------GERGPKG 529
             GPPG+ G  G+DGP G++GPPGP G  G +      G+RG +G
Sbjct: 881  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERG 924

 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 44/114 (38%), Positives = 51/114 (44%), Gaps = 15/114 (13%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G+ G  GPPGP G  G PGFPG                  + G  GEPG PG  G AG  
Sbjct: 279 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGAS 338

Query: 419 GPPGD---------------AGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G PG                AG+ G  GP+G   P G TG +GPKG+ G  G+A
Sbjct: 339 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPDPQGATGPLGPKGQTGKPGIA 392

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 41/97 (42%), Positives = 46/97 (47%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G+ GPPGP+G  G  G PG                    G  G  G PG  G  G  
Sbjct: 732  GEKGEVGPPGPAGSAGARGAPGERGETGPPGTSGIA------GPPGADGQPGAKGEQGEA 785

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  GDAG+ G  GP G+ GP GPTG  GPKG RG +G
Sbjct: 786  GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 822

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 41/98 (41%), Positives = 47/98 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GPPGP G  G PG  G                    G  G  G+PG AG  GL
Sbjct: 512 PGEDGRPGPPGPQGARGQPGVMGFP------------------GPKGANGEPGKAGEKGL 553

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G DG  G++GPPGP G  G +GE+G  G
Sbjct: 554 PGAPGLRGLPGKDGETGAEGPPGPAGPAGERGEQGAPG 591

 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 45/105 (42%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPG  GK GD G PG A                  G+ G PG+ G  G  GL 
Sbjct: 597 GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPR---------GERGFPGERGSPGAQGLQ 647

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGP------KGERGPKGVA 535
           GP G  G+ G DGPKG+ GP GP G  GP       GERG  G+A
Sbjct: 648 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 38/97 (39%), Positives = 44/97 (45%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GP GP G  G PG  G                   +G+ G  G PG  G  GL 
Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  G AG +G KG  GPPGP G+ G +G  G +G
Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 43/112 (38%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
 Frame = +2

Query: 236  PGRMGKDGPPGP------------SGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGE 379
            PG  G  GPPGP             G+ G PG  G                  ++G  G 
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000

Query: 380  PGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            PG PG  G AG  G  GD G AG  GP G  GP G  G  GP+G RG KG A
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1052

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 41/110 (37%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXX---------SIGDAGEPG 385
           EPG +G  GPPGP G  G PG  G                            +G  G PG
Sbjct: 85  EPGTLGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144

Query: 386 DPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G  G  G  G PG+ G  G  GP G +GPPGP G  G  GE G  G A
Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 194

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 40/97 (41%), Positives = 46/97 (47%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G MG  GPPGP+G  G  GF G                     + GEPG+PGV+G  G  
Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQG---------------------NPGEPGEPGVSGPMGPR 173

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GPPG  G  G+DG  G  G  G  G  GP+G RG  G
Sbjct: 174 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPG 210

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 40/101 (39%), Positives = 47/101 (46%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           +PG+ G+ GPPGP G  G PG PG                    G  G  G PG+ G  G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLP------------------GVKGHRGYPGLDGAKG 231

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G PG  G +G+ G  GS GP GP G  G +G  GP G A
Sbjct: 232 EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 42/101 (41%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPG SG  G PG  G+                   G+AG+ GD G  G  G 
Sbjct: 752  PGERGETGPPGTSGIAGPPGADGQPGAKGEQ------------GEAGQKGDAGAPGPQGP 799

Query: 416  IGPPGDAGSAGNDGPKGS---QGPPGPTGNIGPKGERGPKG 529
             G PG  G  G  GPKG+   QGPPG TG  G  G  GP G
Sbjct: 800  SGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 840

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 40/101 (39%), Positives = 48/101 (47%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD---PGVAGN 406
           PG  G +G PG +G+ G PG PG                    G AGE G+   PG +G 
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAEGPPGPAGPAGERGEQGAPGPSGF 595

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GL GPPG  G  G  G +G  G  G  G +GP+GERG  G
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPG 636

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 39/106 (36%), Positives = 46/106 (43%), Gaps = 9/106 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG----- 403
           G  G DG PG  G  G PG  G                   +G  G+ G PG+AG     
Sbjct: 339 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPDPQGATGPLGPKGQTGKPGIAGFKGEQ 398

Query: 404 ----NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                 G  GP G  G AG +G +G++G PG  G IGP GERG  G
Sbjct: 399 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPG 444

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 38/99 (38%), Positives = 45/99 (45%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G+ G  G PGP G  G PG  G                  + G  G  G  G  G+ G
Sbjct: 784  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 843

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPPG  G +G DGPKG++G  GP G  G  G +GP G
Sbjct: 844  NPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 882

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 43/109 (39%), Positives = 47/109 (43%), Gaps = 12/109 (11%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGK------LGDPGFPGRAXXXXXXXXXXXXXXXXSIGD------AGEP 382
            G  G  GPPGPSGK       GD G PGRA                  GD       G P
Sbjct: 843  GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 902

Query: 383  GDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G+AG  G++G PG  G  G  G  G  G PG  G  G  G+RGP G
Sbjct: 903  GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGQQGAPGASGDRGPPG 951

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/102 (40%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G  GP G  G  G+PG PG                  + G AG PG  G  G  G
Sbjct: 307 EAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 366

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPT---GNIGPKGERGPKG 529
             GPP   G+ G  GPKG  G PG     G  GPKGE GP G
Sbjct: 367 PRGPPDPQGATGPLGPKGQTGKPGIAGFKGEQGPKGEPGPAG 408

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 40/99 (40%), Positives = 46/99 (46%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ G  G  G  G PG  G +                + G  G PG  G  G AG
Sbjct: 775  QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG 834

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             +GPPG   S GN GP    GPPGP+G  GPKG RG  G
Sbjct: 835  RVGPPG---SNGNPGPP---GPPGPSGKDGPKGARGDSG 867

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 43/112 (38%), Positives = 47/112 (41%), Gaps = 12/112 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G DGP G SG  G PG                     + G  G  G PG  G AG+
Sbjct: 653 PGTPGTDGPKGASGPAGPPG---------------------AQGPPGLQGMPGERGAAGI 691

Query: 416 IGPPGDAGSAGNDGPKGSQG------------PPGPTGNIGPKGERGPKGVA 535
            GP GD G  G  GP+G+ G            PPGP G  G KGE GP G A
Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 38/99 (38%), Positives = 44/99 (44%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  GPPG  G+ GD G  G                    G  GE G PG+ G +G
Sbjct: 874  EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 933

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G  G  G++G+ GP G  GPPG TG  G  G  G  G
Sbjct: 934  EPGQQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 972

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN--- 406
           P   G  GP GP G+ G PG  G                  + G AGE G  G  G    
Sbjct: 371 PDPQGATGPLGPKGQTGKPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430

Query: 407 AGLIGPPGDAGSAGN---------DGPKGSQGPPGPTGNIGPKGERGPKG 529
            G IGPPG+ G+ GN          GPKG+ G  GP+G  GPKG  G  G
Sbjct: 431 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 44/126 (34%), Positives = 49/126 (38%), Gaps = 27/126 (21%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEP---------- 382
           E G+ GK G  GP G  G  GFPG                  + G+AG P          
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 383 --------GDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNI---------GPKG 511
                   G  G+ G  G  GP G AG+ GNDG  G  GPPGP G           G KG
Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 306

Query: 512 ERGPKG 529
           E GP G
Sbjct: 307 EAGPTG 312

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/108 (36%), Positives = 45/108 (41%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G DGP G  G  G  G  G+                   G +GEPG  G  G +G
Sbjct: 886  EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGQQGAPGASG 945

Query: 413  LIGPP---------GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPP         G AG  G +G  G+ GPPG  G  G KG+RG  G
Sbjct: 946  DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 993

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 39/99 (39%), Positives = 46/99 (46%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G++G PGP G  G PG  GR                 + G  G  G PG AG  G
Sbjct: 241 ESGSPGENGSPGPMGPRGLPGERGRTGPAG------------AAGARGNDGQPGPAGPPG 288

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            +GP G  G  G  G KG     GPTG  GP+G +GP+G
Sbjct: 289 PVGPAGGPGFPGAPGAKGE---AGPTGARGPEGAQGPRG 324

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 40/107 (37%), Positives = 47/107 (43%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGD------PGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
           PG  G  G  GP G  GD       G PG+                 + G+ GE G PG 
Sbjct: 683 PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 742

Query: 398 AGNAGLIGPPGDAGSAGNDGPKGSQ---GPPGPTGNIGPKGERGPKG 529
           AG+AG  G PG+ G  G   P G+    GPPG  G  G KGE+G  G
Sbjct: 743 AGSAGARGAPGERGETG---PPGTSGIAGPPGADGQPGAKGEQGEAG 786

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 34/89 (38%), Positives = 38/89 (42%)
 Frame = +2

Query: 263 PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLIGPPGDAGS 442
           PGP G+ G+PG                      +G  G PG  G AG  G  G  GD G 
Sbjct: 31  PGPKGQKGEPG-----------------DIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGE 73

Query: 443 AGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  GP+G  G PG  GN GP G  GP G
Sbjct: 74  KGAPGPRGRDGEPGTLGNPGPPGPPGPPG 102

 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 40/119 (33%), Positives = 46/119 (38%), Gaps = 21/119 (17%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD--------- 388
           PG  G  GP G  G  G+PG PG +                  G+AG+PG          
Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202

Query: 389 ------------PGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                       PGV G+ G  G  G  G AG  G KG  G PG  G+ GP G RG  G
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 261

 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 28/129 (21%)
 Frame = +2

Query: 233 EPGRM----GKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVA 400
           EPG +    G  GPPGP G  G+ G                       GD G+ G+ G  
Sbjct: 39  EPGDIKDIVGPKGPPGPQGPAGEQG---------------------PRGDRGDKGEKGAP 77

Query: 401 GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGN------------------------IGPK 508
           G  G  G PG  G+ G  GP G  GPPG  GN                        +GP 
Sbjct: 78  GPRGRDGEPGTLGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137

Query: 509 GERGPKGVA 535
           G RGP G A
Sbjct: 138 GPRGPPGPA 146
>sp|P20909|CA1B_RAT Collagen alpha 1(XI) chain precursor
          Length = 482

 Score =  156 bits (394), Expect = 2e-37
 Identities = 122/419 (29%), Positives = 179/419 (42%), Gaps = 10/419 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+DGPPGP   LG PG PG                   IG  GE G+ G  G  G 
Sbjct: 98   PGAAGQDGPPGP---LGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 154

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G PG  G  G  GP G  GPPGP G  GP G +G KG +                    
Sbjct: 155  QGSPGAKGDGGIPGPAGPIGPPGPPGLPGPAGPKGNKGSSGPTGQKGDSGMPGPPGPPGP 214

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                        I   ++T    E  Q D       + +D +D 
Sbjct: 215  PGEVIQPLP-------------------ILSPKKTRRHTESIQADAGD----NILDYSDG 251

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
             E+IF +L  L   ++++  P G++T PAR+C D+Q  + +  +G Y+IDPN G   D+ 
Sbjct: 252  MEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSF 311

Query: 956  YVFCNFEK-LETCIEPEVSN--YKKTSYMKSH-SSWFSILASLNKQVSY------KIPKE 1105
             V+CNF    ETCI P+  +   + +S+ K    SW+S      K +SY       I   
Sbjct: 312  KVYCNFTAGGETCIYPDKKSEGVRLSSWPKEKPGSWYSEF-KRGKLLSYLDVEGNSINMV 370

Query: 1106 QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDDDLF 1285
            Q+ FL+L + S  QNFT +C       D        Y+ +L+ LG +++ ++ +N+  + 
Sbjct: 371  QMTFLKLLTSSARQNFTYNCHQSTAWYD---VLSGSYDKALRFLGSNDEEMSYDNNPHI- 426

Query: 1286 QYQIIEDNCKGKSSSGRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVCFSG 1462
              + + D C  +    + VI++   +  ++PI D          Q K G E+GP CF G
Sbjct: 427  --KALYDGCASRKGYEKTVIEINTPKIDQVPIIDVMINDFGDQNQ-KFGFEVGPACFLG 482

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 43/103 (41%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G+ GPPGPSG+ G PG PG+                 + G+AG  G PG  G  G
Sbjct: 13  EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGASGSEGGQGEKGAKGEAGAEGPPGKTGPVG 72

Query: 413 LIGP---PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             GP   PG  G  G  GP G QG PG  G  GP G  GP G+
Sbjct: 73  PQGPSGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPLGPPGL 115

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 41/98 (41%), Positives = 48/98 (48%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG+ G  GP GPSGK G  G  G                   +G+ G PG  G  G  G 
Sbjct: 65  PGKTGPVGPQGPSGKPGPEGLRG---------------IPGPVGEQGLPGAAGQDGPPGP 109

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           +GPPG  G  G+ G KG +G PG  G IGP GE+G KG
Sbjct: 110 LGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 147

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 37/94 (39%), Positives = 44/94 (46%)
 Frame = +2

Query: 248 GKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLIGPP 427
           G+DG  G  G+ GDPG PG                    G+AG PG PG  G  G  G  
Sbjct: 3   GQDGVGGDKGEDGDPGQPGPPGPS---------------GEAGPPGPPGKRGPPGASGSE 47

Query: 428 GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  G  G  G  G++GPPG TG +GP+G  G  G
Sbjct: 48  GGQGEKGAKGEAGAEGPPGKTGPVGPQGPSGKPG 81

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 38/101 (37%), Positives = 43/101 (42%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           + G  G  G PGP G  G+ G PG                  + G  G  G+ G  G AG
Sbjct: 10  DKGEDGDPGQPGPPGPSGEAGPPG---------PPGKRGPPGASGSEGGQGEKGAKGEAG 60

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             GPPG  G  G  GP G  GP G  G  GP GE+G  G A
Sbjct: 61  AEGPPGKTGPVGPQGPSGKPGPEGLRGIPGPVGEQGLPGAA 101

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 30/57 (52%), Positives = 36/57 (63%)
 Frame = +2

Query: 365 GDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           GD GE GDPG  G      PPG +G AG  GP G +GPPG +G+ G +GE+G KG A
Sbjct: 9   GDKGEDGDPGQPG------PPGPSGEAGPPGPPGKRGPPGASGSEGGQGEKGAKGEA 59

 Score = 43.5 bits (101), Expect = 0.002
 Identities = 20/42 (47%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
 Frame = +2

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKG---ERGPKGVA 535
           G  G  G  G DG  G  GPPGP+G  GP G   +RGP G +
Sbjct: 3   GQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAS 44

 Score = 42.0 bits (97), Expect = 0.005
 Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
 Frame = +2

Query: 398 AGNAGLIGPPGDAGSAGNDGPKGSQ---GPPGPTGNIGPKGERGPKG 529
           AG  G+ G  G+ G  G  GP G     GPPGP G  GP G  G +G
Sbjct: 2   AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGASGSEG 48
>sp|P02465|CO1A2_BOVIN Collagen alpha 2(I) chain precursor
          Length = 1364

 Score =  154 bits (389), Expect = 7e-37
 Identities = 123/420 (29%), Positives = 177/420 (42%), Gaps = 13/420 (3%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  GP G  G  G+PG  G                    GD GEPGD G  G  GL
Sbjct: 961  PGPQGPVGPVGKHGNRGEPGPAGAVGPAGAVGPRGPSGPQGIRGDKGEPGDKGPRGLPGL 1020

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G  G  G  G  G  G QG PG  G  GP+G  GP G A                    
Sbjct: 1021 KGHNGLQGLPGLAGHHGDQGAPGAVGPAGPRGPAGPSGPAGKDGRIGQPGAVGPAGIRGS 1080

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                     ++  F       + + ++ D+P++   +S+ P D 
Sbjct: 1081 QGSQGPAGPPGPPGPPGPPGPSGGGYEFGF-------DGDFYRADQPRSP--TSLRPKDY 1131

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
            + D    L  L+  ++ L  P GS+  PAR+C D++  +   S+G Y+IDPN G   DAI
Sbjct: 1132 EVDA--TLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAI 1189

Query: 956  YVFCNFEKLETCI--EPE---VSNYKKTSYMKSHSSWFSILASLNKQVSYKI----PKE- 1105
             V+C+F   ETCI  +PE   V N+ + S  K H  W     +   Q  Y +     KE 
Sbjct: 1190 KVYCDFSTGETCIRAQPEDIPVKNWYRNSKAKKH-VWVGETINGGTQFEYNVEGVTTKEM 1248

Query: 1106 --QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDDD 1279
              QL F++L +   SQN T  C N    S   +++E        +L   N +  V   + 
Sbjct: 1249 ATQLAFMRLLANHASQNITYHCKN----SIAYMDEETGNLKKAVILQGSNDVELVAEGNS 1304

Query: 1280 LFQYQIIEDNCKGKSSS-GRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVCF 1456
             F Y ++ D C  K++   + +I+ + ++P RLPI D     +  + Q +I + IGPVCF
Sbjct: 1305 RFTYTVLVDGCSKKTNEWQKTIIEYKTNKPSRLPILDIAPLDIGGADQ-EIRLNIGPVCF 1363

 Score = 81.3 bits (199), Expect = 7e-15
 Identities = 44/100 (44%), Positives = 48/100 (48%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGPSG  G PG PG A                  G+ G  G PG  G  G 
Sbjct: 787  PGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRSGETGASGPPGFVGEKGP 846

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G PG AG  G  GP+G  G PG  G  G +GERG  GVA
Sbjct: 847  SGEPGTAGPPGTPGPQGLLGAPGFLGLPGSRGERGLPGVA 886

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 42/97 (43%), Positives = 46/97 (47%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G +GPPGP+G  GD G PG                    G +G PG PG AG  GL 
Sbjct: 761  GPSGPNGPPGPAGSRGDGGPPGATGFPGAAGRTGPPGPS---GISGPPGPPGPAGKEGLR 817

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP GD G  G  G  G+ GPPG  G  GP GE G  G
Sbjct: 818  GPRGDQGPVGRSGETGASGPPGFVGEKGPSGEPGTAG 854

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 47/110 (42%), Positives = 51/110 (46%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PGP G LG PGF G                    G  GEPG  G+AG  G
Sbjct: 849  EPGTAGPPGTPGPQGLLGAPGFLGLPGSRGERGLPGVA------GSVGEPGPLGIAGPPG 902

Query: 413  LIGPPGDAGS---------AGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
              GPPG+ G+         AG DG  G+ GPPG  G  G KGERG  G A
Sbjct: 903  ARGPPGNVGNPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNA 952

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 41/100 (41%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS--IGDAGEPGDPGVAGNA 409
           PGR G DG PGP G  G PG PG                     +G  G PG  G  G  
Sbjct: 50  PGRDGDDGIPGPPGPPGPPGPPGLGGNFAAQFDAKGGGPGPMGLMGPRGPPGASGAPGPQ 109

Query: 410 GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  GPPG+ G  G  GP G++GPPGP G  G  G  G  G
Sbjct: 110 GFQGPPGEPGEPGQTGPAGARGPPGPPGKAGEDGHPGKPG 149

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 43/105 (40%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPG---PSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            EPG +G  GPPG   P G +G+PG    PG A                  G  GE G PG
Sbjct: 891  EPGPLGIAGPPGARGPPGNVGNPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 950

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             AG  G  G PG  G  G  G  G++G PGP G +GP G  GP+G
Sbjct: 951  NAGPVGAAGAPGPQGPVGPVGKHGNRGEPGPAGAVGPAGAVGPRG 995

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 43/98 (43%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG MG  GP GP G  G PG  G                    G  GEPG+PG  G AG 
Sbjct: 88  PGPMGLMGPRGPPGASGAPGPQGFQ------------------GPPGEPGEPGQTGPAGA 129

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG  G AG DG  G  G PG  G +GP+G RG  G
Sbjct: 130 RGPPGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPG 167

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/106 (39%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPG------FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG  G++G PG +G  G PG       PG A                 IG AG PG PG
Sbjct: 198 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 257

Query: 395 VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G +GP G+ G AG  GP+G  G PG +G +GP G  G  G+
Sbjct: 258 APGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL 303

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/109 (38%), Positives = 51/109 (46%), Gaps = 9/109 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGK---------LGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPG 385
           EPG +G+ GPPGPSG+         +G  G PG                    G  G  G
Sbjct: 360 EPGAVGQPGPPGPSGEEGKRGSTGEIGPAGPPGPPGLRGNPGSRGLPGADGRAGVMGPAG 419

Query: 386 DPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G AG+ GP GD+G  G  G  G +G PG  GNIGP G+ GP G+
Sbjct: 420 SRGATGPAGVRGPNGDSGRPGEPGLMGPRGFPGSPGNIGPAGKEGPVGL 468

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 41/98 (41%), Positives = 45/98 (45%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G +G PG  GR                   G  G  GDPG AG  G 
Sbjct: 451 PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPSGDPGKAGEKGH 510

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G  G+ G DG  G+QGPPG  G  G KGE+GP G
Sbjct: 511 AGLAGARGAPGPDGNNGAQGPPGLQGVQGGKGEQGPAG 548

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 44/114 (38%), Positives = 51/114 (44%), Gaps = 17/114 (14%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN---- 406
           G  G+ GPPGP G+ GD G PG                    G  G PG PG+ GN    
Sbjct: 39  GPRGERGPPGPPGRDGDDGIPGPP------------------GPPGPPGPPGLGGNFAAQ 80

Query: 407 ----------AGLIGPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKG 529
                      GL+GP G  G++G  GP+G QGPPG  G     GP G RGP G
Sbjct: 81  FDAKGGGPGPMGLMGPRGPPGASGAPGPQGFQGPPGEPGEPGQTGPAGARGPPG 134

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 39/97 (40%), Positives = 43/97 (44%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G+ GP GP+G  G  G PG                    G+ G  G  G AG AG  
Sbjct: 689 GDRGEAGPAGPAGPAGPRGSPGER------------------GEVGPAGPNGFAGPAGAA 730

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G PG  G  G  GPKG  GP GPTG +G  G  GP G
Sbjct: 731 GQPGAKGERGTKGPKGENGPVGPTGPVGAAGPSGPNG 767

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 40/106 (37%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG---------DAGEPGDP 391
           G +G  GPPGP G  G+PG  G                  + G         D+G PG+P
Sbjct: 383 GEIGPAGPPGPPGLRGNPGSRGLPGADGRAGVMGPAGSRGATGPAGVRGPNGDSGRPGEP 442

Query: 392 GVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G+ G  G  G PG+ G AG +GP G  G  G  G IGP G RG  G
Sbjct: 443 GLMGPRGFPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPG 488

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 43/107 (40%), Positives = 51/107 (47%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD--------- 388
           PG  G  G  G  G  G PGF G                  + G+AG+PG+         
Sbjct: 532 PGLQGVQGGKGEQGPAGPPGFQG------------LPGPAGTAGEAGKPGERGIPGEFGL 579

Query: 389 PGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           PG AG  G  GPPG++G+AG  GP GS+GP GP G  G KGE G  G
Sbjct: 580 PGPAGARGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 626

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 43/101 (42%), Positives = 46/101 (45%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG +G  G  GPSG  G PG  G A                  GD G PG  G  G  G
Sbjct: 621 EPGVVGAPGTAGPSGPSGLPGERGAAGIPGGKGEKGETGLR---GDIGSPGRDGARGAPG 677

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            IG PG AG+ G+ G  G  GP GP G  G  GERG  G A
Sbjct: 678 AIGAPGPAGANGDRGEAGPAGPAGPAGPRGSPGERGEVGPA 718

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 38/97 (39%), Positives = 41/97 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GP GP+G  G PG  G                    G AG  G PG  G  G  
Sbjct: 692 GEAGPAGPAGPAGPRGSPGERGEVGPAGPNGFA---------GPAGAAGQPGAKGERGTK 742

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G+ G  G  GP G+ GP GP G  GP G RG  G
Sbjct: 743 GPKGENGPVGPTGPVGAAGPSGPNGPPGPAGSRGDGG 779

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 41/107 (38%), Positives = 48/107 (44%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GP GP+G  G  G  G+                   G  G  G  G AG +G 
Sbjct: 709  PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGTKGPKGEN---GPVGPTGPVGAAGPSGP 765

Query: 416  IGPPGDAGSAGNDGPKGS---------QGPPGPTGNIGPKGERGPKG 529
             GPPG AGS G+ GP G+          GPPGP+G  GP G  GP G
Sbjct: 766  NGPPGPAGSRGDGGPPGATGFPGAAGRTGPPGPSGISGPPGPPGPAG 812

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 39/102 (38%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
           PG  G +G PG  G  G PG    PG                  + G  GEPG  G  G 
Sbjct: 295 PGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGE 354

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +G  G PG  G  G  GP G +G  G TG IGP G  GP G+
Sbjct: 355 SGNKGEPGAVGQPGPPGPSGEEGKRGSTGEIGPAGPPGPPGL 396

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 42/99 (42%), Positives = 43/99 (43%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PG  G  G  G PG A                  G  G  G  G AG  G
Sbjct: 1008 EPGDKGPRGLPGLKGHNGLQGLPGLAGHHGDQGAPGAVGPA---GPRGPAGPSGPAGKDG 1064

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             IG PG  G AG  G +GSQGP GP G  GP G  GP G
Sbjct: 1065 RIGQPGAVGPAGIRGSQGSQGPAGPPGPPGPPGPPGPSG 1103

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 40/102 (39%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  GP GP G  G PGFPG                    G  GE G PG++G    +
Sbjct: 236 GSVGPVGPAGPIGSAGPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGP---V 292

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKGVA 535
           GPPG+ G+ G  G KG+ G PG  G     GP+G  GP G A
Sbjct: 293 GPPGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 334

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 39/104 (37%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGK---LGDPGFPGRAXXXXXXXXXXXXXXXXSIG---DAGEPGDPGVA 400
            G  G DGPPG  G+    G+ G+PG A                 +G   + GEPG  G  
Sbjct: 926  GNPGNDGPPGRDGQPGHKGERGYPGNAGPVGAAGAPGPQGPVGPVGKHGNRGEPGPAGAV 985

Query: 401  GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G AG +GP G +G  G  G KG  G  GP G  G KG  G +G+
Sbjct: 986  GPAGAVGPRGPSGPQGIRGDKGEPGDKGPRGLPGLKGHNGLQGL 1029

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 40/105 (38%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GP GP+G  G+PG  G                    G AG  G PG  GN G 
Sbjct: 469 PGIDGRPGPIGPAGARGEPGNIGFPGPKGPSGDPGKAGEKGHAGLAGARGAPGPDGNNGA 528

Query: 416 IGPP------GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            GPP      G  G  G  GP G QG PGP G  G  G+ G +G+
Sbjct: 529 QGPPGLQGVQGGKGEQGPAGPPGFQGLPGPAGTAGEAGKPGERGI 573

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/100 (39%), Positives = 45/100 (45%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PGP G+LG  G PG A                 +G  G PG  G+ G  G  
Sbjct: 251 GPPGFPGAPGPKGELGPVGNPGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLPGAKGAA 310

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPK---GERGPKG 529
           G PG AG+ G  GP+G  GP G  G  G +   GE GP G
Sbjct: 311 GLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAG 350

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/101 (38%), Positives = 46/101 (45%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G+ G PG  G A                  G+ GEPG  G  G AG 
Sbjct: 574 PGEFGLPGPAGARGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAPGTAGP 633

Query: 416 IGP---PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP   PG+ G+AG  G KG +G  G  G+IG  G  G +G
Sbjct: 634 SGPSGLPGERGAAGIPGGKGEKGETGLRGDIGSPGRDGARG 674

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 38/99 (38%), Positives = 40/99 (40%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G  GP GP G  G  G PG                    G  G  G  G  G  G
Sbjct: 282 EVGLPGLSGPVGPPGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARG 341

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           L+G PG AGS G  G KG  G  G  G  GP GE G +G
Sbjct: 342 LVGEPGPAGSKGESGNKGEPGAVGQPGPPGPSGEEGKRG 380

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 37/98 (37%), Positives = 42/98 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPG  G  G  G  G A                  G  GE G PG +G AG  
Sbjct: 542 GEQGPAGPPGFQGLPGPAGTAGEAGKPGERGIPGEFGLPGPAGARGERGPPGESGAAGPT 601

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           GP G  G +G  GP G++G PG  G  G  G  GP G+
Sbjct: 602 GPIGSRGPSGPPGPDGNKGEPGVVGAPGTAGPSGPSGL 639

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 41/104 (39%), Positives = 44/104 (42%), Gaps = 3/104 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
           E G  G  G PG  G  G PG    PG A                  G  G PG+ G  G
Sbjct: 657 ETGLRGDIGSPGRDGARGAPGAIGAPGPAGANGDRGEAGPAGPAGPAGPRGSPGERGEVG 716

Query: 404 NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            AG  G  G AG+AG  G KG +G  GP G  GP G  GP G A
Sbjct: 717 PAGPNGFAGPAGAAGQPGAKGERGTKGPKGENGPVGPTGPVGAA 760

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 39/102 (38%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN-- 406
           + G  G  GPPGP GK G+ G PG+                   G  G PG  G+ G+  
Sbjct: 123 QTGPAGARGPPGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNG 182

Query: 407 -AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GL G PG  G  G  G  G  G PG TG  G  GERG  G
Sbjct: 183 LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVG 224

 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 38/104 (36%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ G  GP G+ G  G  G                  S GD G PG  G  G AG
Sbjct: 732  QPGAKGERGTKGPKGENGPVGPTGPVGAAGPSGPNGPPGPAGSRGDGGPPGATGFPGAAG 791

Query: 413  LIGPPGDAGSAGNDGPKG---SQGPPGPTGNIGPKGERGPKGVA 535
              GPPG +G +G  GP G    +G  GP G+ GP G  G  G +
Sbjct: 792  RTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRSGETGAS 835

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 44/123 (35%), Positives = 51/123 (41%), Gaps = 24/123 (19%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG------DAGEPGDPG 394
           +PGR G+ G  GP G  G PG PG                    G      + G PG+ G
Sbjct: 147 KPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENG 206

Query: 395 VAGNAGL---------IGPPGDAGSAGND---------GPKGSQGPPGPTGNIGPKGERG 520
             G  G          +G PG AG+ G+D         GP GS GPPG  G  GPKGE G
Sbjct: 207 TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGELG 266

Query: 521 PKG 529
           P G
Sbjct: 267 PVG 269

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 42/108 (38%), Positives = 47/108 (43%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG +G  GP GPSG   DPG  G                  + G  G PG  GV G  G
Sbjct: 486 EPGNIGFPGPKGPSG---DPGKAGEKGHAGLAGARGAPGPDGNNGAQGPPGLQGVQGGKG 542

Query: 413 LIGP---------PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GP         PG AG+AG  G  G +G PG  G  GP G RG +G
Sbjct: 543 EQGPAGPPGFQGLPGPAGTAGEAGKPGERGIPGEFGLPGPAGARGERG 590

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 37/97 (38%), Positives = 42/97 (43%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PG  G  G PG  G A                S G++G  G+PG  G  G  
Sbjct: 311 GLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGAVGQPGPP 370

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G+ G  G+ G  G  GPPGP G  G  G RG  G
Sbjct: 371 GPSGEEGKRGSTGEIGPAGPPGPPGLRGNPGSRGLPG 407

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 36/98 (36%), Positives = 41/98 (41%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PGP G  G PG PG                    G+ G PG PG  G  G++
Sbjct: 98  GPPGASGAPGPQGFQGPPGEPGEPGQTGPAGARGPPGPPGKAGEDGHPGKPGRPGERGVV 157

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           GP G  G  G  G  G +G  G  G  G KG+ G  GV
Sbjct: 158 GPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 195

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 39/99 (39%), Positives = 45/99 (45%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G  G+PG PG+                   G  G PG PG AG  G 
Sbjct: 100 PGASGAPGPQGFQGPPGEPGEPGQTGPA---------------GARGPPGPPGKAGEDGH 144

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G PG  G  G  GP+G++G PG  G  G KG RG  G+
Sbjct: 145 PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL 183

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 36/100 (36%), Positives = 42/100 (42%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG +G  G  G  G +G+PG  G                    G +GE G  G  G  G 
Sbjct: 328 PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGAVGQPGPPGPSGEEGKRGSTGEIGP 387

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GPPG  G  GN G +G  G  G  G +GP G RG  G A
Sbjct: 388 AGPPGPPGLRGNPGSRGLPGADGRAGVMGPAGSRGATGPA 427

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 35/99 (35%), Positives = 44/99 (44%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G +G+ G PG  G                    G++G  G  G  G+ G 
Sbjct: 550 PGFQGLPGPAGTAGEAGKPGERGIPGEFGLPGPAGARGERGPPGESGAAGPTGPIGSRGP 609

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            GPPG  G+ G  G  G+ G  GP+G  G  GERG  G+
Sbjct: 610 SGPPGPDGNKGEPGVVGAPGTAGPSGPSGLPGERGAAGI 648

 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 39/107 (36%), Positives = 43/107 (40%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ G  GP+G  G PG PG+A                  G  G PG+ GV G  G 
Sbjct: 115 PGEPGEPGQTGPAGARGPPGPPGKAGEDGHP------------GKPGRPGERGVVGPQGA 162

Query: 416 IGPPGD---------AGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG           G  G DG KG  G PG  G  G  GE G  G
Sbjct: 163 RGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 209

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 27/66 (40%), Positives = 28/66 (42%), Gaps = 14/66 (21%)
 Frame = +2

Query: 374 GEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPT--------------GNIGPKG 511
           G  GD G  G  G  GPPG  G  G  GP G  GPPGP               G  GP G
Sbjct: 33  GPSGDRGPRGERGPPGPPGRDGDDGIPGPPGPPGPPGPPGLGGNFAAQFDAKGGGPGPMG 92

Query: 512 ERGPKG 529
             GP+G
Sbjct: 93  LMGPRG 98

 Score = 37.7 bits (86), Expect = 0.092
 Identities = 21/50 (42%), Positives = 23/50 (46%)
 Frame = +2

Query: 383 GDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G  G  G  G  GPPG  G  G+DG  G  GPPGP          GP G+
Sbjct: 33  GPSGDRGPRGERGPPGPPGRDGDDGIPGPPGPPGPP---------GPPGL 73
>sp|O46392|CO1A2_CANFA Collagen alpha 2(I) chain precursor
          Length = 1366

 Score =  152 bits (383), Expect = 3e-36
 Identities = 121/420 (28%), Positives = 175/420 (41%), Gaps = 13/420 (3%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  GP G  G  G+PG  G                    GD GEPG+ G  G  GL
Sbjct: 963  PGPHGPVGPTGKHGNRGEPGPAGSVGPVGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGL 1022

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G  G  G  G  G  G QG PG  G  GP+G  GP G A                    
Sbjct: 1023 KGHNGLQGLPGLAGQHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGQPGTVGPAGIRGS 1082

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                     +   +       E + ++ D+P++    S+ P D 
Sbjct: 1083 QGSQGPAGPPGPPGPPGPPGPSGGGYDFGY-------EGDFYRADQPRSPP--SLRPKDY 1133

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
            + D    L  L+  ++ L  P GS+  PAR+C D++  +   S+G Y+IDPN G   DAI
Sbjct: 1134 EVDA--TLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEWSSGYYWIDPNQGCTMDAI 1191

Query: 956  YVFCNFEKLETCI--EPE---VSNYKKTSYMKSHSSWFSILASLNKQVSYKI----PKE- 1105
             V+C+F   ETCI  +PE     N+ + S +K H  W     +   Q  Y +     KE 
Sbjct: 1192 KVYCDFSTGETCIRAQPENIPAKNWYRNSKVKKH-IWLGETINGGTQFEYNVEGVTTKEM 1250

Query: 1106 --QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDDD 1279
              QL F++L +   SQN T  C N    S   +++E        +L   N +  V   + 
Sbjct: 1251 ATQLAFMRLLANHASQNITYHCKN----SIAYMDEETGNLKKAVILQGSNDVELVAEGNS 1306

Query: 1280 LFQYQIIEDNCKGKSSSGR-VVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVCF 1456
             F Y ++ D C  K++  R  +I+ + ++P RLPI D     +  + Q +  V++GPVCF
Sbjct: 1307 RFTYTVLVDGCSKKTNEWRKTIIEYKTNKPSRLPILDIAPLDIGDADQ-EFRVDVGPVCF 1365

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 44/100 (44%), Positives = 48/100 (48%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGPSG  G PG PG A                  G+ G  G PG  G  G 
Sbjct: 789  PGAAGRTGPPGPSGITGPPGPPGAAGKEGLRGPRGDQGPVGRTGETGASGPPGFTGEKGP 848

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G PG AG  G  GP+G  G PG  G  G +GERG  GVA
Sbjct: 849  SGEPGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVA 888

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 43/97 (44%), Positives = 46/97 (47%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G +GPPGP+G  GD G PG                    G  G PG PG AG  GL 
Sbjct: 763  GPSGPNGPPGPAGSRGDGGPPGATGFPGAAGRTGPPGPS---GITGPPGPPGAAGKEGLR 819

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP GD G  G  G  G+ GPPG TG  GP GE G  G
Sbjct: 820  GPRGDQGPVGRTGETGASGPPGFTGEKGPSGEPGTAG 856

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 44/98 (44%), Positives = 47/98 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG MG  GP GP G  G PG  G                    G AGEPG+PG  G AG 
Sbjct: 90  PGPMGLMGPRGPPGASGAPGPQGFQ------------------GPAGEPGEPGQTGPAGA 131

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG  G AG DG  G  G PG  G +GP+G RG  G
Sbjct: 132 RGPPGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPG 169

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 43/106 (40%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPG------FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG  G++G PG +G  G PG       PG A                 IG AG PG PG
Sbjct: 200 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259

Query: 395 VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G IGP G+ G AG  GP+G  G PG +G +GP G  G  G+
Sbjct: 260 APGPKGEIGPVGNPGPAGPAGPRGEVGLPGVSGPVGPPGNPGANGL 305

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 42/105 (40%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPG---PSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            EPG +G  GPPG   P G +G PG    PG A                  G  GE G PG
Sbjct: 893  EPGPLGIAGPPGARGPPGAVGAPGVNGAPGEAGRDGNPGNDGPPGRDGQAGHKGERGYPG 952

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G  G +G PG  G  G  G  G++G PGP G++GP G  GP+G
Sbjct: 953  NIGPVGAVGAPGPHGPVGPTGKHGNRGEPGPAGSVGPVGAVGPRG 997

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 41/98 (41%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G +G PG  GR                   G  G  GDPG  G+ G 
Sbjct: 453 PGAPGNVGPAGKEGPMGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGH 512

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G  G+ G DG  G+QGPPGP G  G KGE+GP G
Sbjct: 513 AGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPAG 550

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 43/109 (39%), Positives = 50/109 (45%), Gaps = 9/109 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS---------IGDAGEPG 385
           EPG  G  GPPGPSG+ G  G  G A                S          G  G PG
Sbjct: 362 EPGSAGAQGPPGPSGEEGKRGPNGEAGSAGPSGPPGLRGSPGSRGLPGADGPAGVMGPPG 421

Query: 386 DPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             G  G AG+ GP GD+G  G  G  G +G PG  GN+GP G+ GP G+
Sbjct: 422 PRGATGPAGVRGPNGDSGRPGEPGLMGPRGFPGAPGNVGPAGKEGPMGL 470

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 45/108 (41%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PGP G LG PG  G                    G  GEPG  G+AG  G
Sbjct: 851  EPGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVA------GSVGEPGPLGIAGPPG 904

Query: 413  LIGPPGDAGS---------AGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPPG  G+         AG DG  G+ GPPG  G  G KGERG  G
Sbjct: 905  ARGPPGAVGAPGVNGAPGEAGRDGNPGNDGPPGRDGQAGHKGERGYPG 952

 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 44/103 (42%), Positives = 50/103 (48%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGE---PGD---PGVA 400
           G  G  GPPGP G  G  G  G A                 +G  GE   PG+   PG A
Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPAGTAGEVGKPGERGLPGEFGLPGPA 585

Query: 401 GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  G  GPPG++G+AG  GP GS+GP GP G  G KGE G  G
Sbjct: 586 GPRGERGPPGESGAAGPSGPIGSRGPSGPPGPDGNKGEPGVLG 628

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 41/98 (41%), Positives = 44/98 (44%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG MG  GP G +G  G+ G  G A                  G+ G  G  G AG AG 
Sbjct: 678 PGAMGAPGPAGATGDRGEAGPAGPAGPAGPRGTPGER------GEVGPAGPNGFAGPAGA 731

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G  GPKG  GP GPTG IG  G  GP G
Sbjct: 732 AGQPGAKGERGTKGPKGENGPVGPTGPIGSAGPSGPNG 769

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 39/98 (39%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  G  GP+G +G PG  G                    GD+G PG+PG+ G  G 
Sbjct: 402 PGSRGLPGADGPAGVMGPPGPRGATGPAGVRGPN---------GDSGRPGEPGLMGPRGF 452

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG+ G AG +GP G  G  G  G IGP G RG  G
Sbjct: 453 PGAPGNVGPAGKEGPMGLPGIDGRPGPIGPAGARGEPG 490

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 39/97 (40%), Positives = 42/97 (43%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G+ GP GP+G  G  G PG                    G AG  G PG  G  G  
Sbjct: 691 GDRGEAGPAGPAGPAGPRGTPGERGEVGPAGPNGFA------GPAGAAGQPGAKGERGTK 744

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G+ G  G  GP GS GP GP G  GP G RG  G
Sbjct: 745 GPKGENGPVGPTGPIGSAGPSGPNGPPGPAGSRGDGG 781

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 43/108 (39%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD---PGVAG 403
            E G  G +G  GP+G  G PG  G                   IG AG  G    PG AG
Sbjct: 716  EVGPAGPNGFAGPAGAAGQPGAKGERGTKGPKGENGPVGPTGPIGSAGPSGPNGPPGPAG 775

Query: 404  NAGLIGP------PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            + G  GP      PG AG  G  GP G  GPPGP G  G +G RGP+G
Sbjct: 776  SRGDGGPPGATGFPGAAGRTGPPGPSGITGPPGPPGAAGKEGLRGPRG 823

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 40/114 (35%), Positives = 45/114 (39%), Gaps = 15/114 (13%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPG---------------FPGRAXXXXXXXXXXXXXXXXSIGDA 373
           G  G  GPPGP G  G+PG                PG                    G+ 
Sbjct: 607 GSRGPSGPPGPDGNKGEPGVLGAPGTAGASGPGGLPGERGAAGIPGGKGEKGETGLRGEI 666

Query: 374 GEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G PG  G  G  G +G PG AG+ G+ G  G  GP GP G  G  GERG  G A
Sbjct: 667 GNPGRDGARGAPGAMGAPGPAGATGDRGEAGPAGPAGPAGPRGTPGERGEVGPA 720

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 41/102 (40%), Positives = 48/102 (47%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  GP GP G  G PGFPG                    G  GE G PGV+G    +
Sbjct: 238 GSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGPVGNPGPAGPAGPRGEVGLPGVSGP---V 294

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKGVA 535
           GPPG+ G+ G  G KG+ G PG  G     GP+G  GP G A
Sbjct: 295 GPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 42/109 (38%), Positives = 46/109 (42%), Gaps = 9/109 (8%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  G PGP G  G  G  G                    G AG  G PG +G  G 
Sbjct: 321 PGLPGPRGIPGPVGAAGATGARGIVGEPGPAGSKGESGNKGEPGSAGAQGPPGPSGEEGK 380

Query: 416 IGPPGDAGSAGNDGPKGSQGPPG---------PTGNIGPKGERGPKGVA 535
            GP G+AGSAG  GP G +G PG         P G +GP G RG  G A
Sbjct: 381 RGPNGEAGSAGPSGPPGLRGSPGSRGLPGADGPAGVMGPPGPRGATGPA 429

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 43/115 (37%), Positives = 49/115 (42%), Gaps = 19/115 (16%)
 Frame = +2

Query: 242 RMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN----- 406
           R G  G  GP G+ G PG PGR                   G  G PG PG+ GN     
Sbjct: 31  RKGPTGDRGPRGERGPPGPPGRDGDDGIPGPP---------GPPGPPGPPGLGGNFAAQY 81

Query: 407 -----------AGLIGPPGDAGSAGNDGPKGSQGP---PGPTGNIGPKGERGPKG 529
                       GL+GP G  G++G  GP+G QGP   PG  G  GP G RGP G
Sbjct: 82  DGKGVGLGPGPMGLMGPRGPPGASGAPGPQGFQGPAGEPGEPGQTGPAGARGPPG 136

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 38/99 (38%), Positives = 41/99 (41%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GP GP+G  G PG  G                    G  GE G  G  G  G +
Sbjct: 694 GEAGPAGPAGPAGPRGTPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGTKGPKGENGPV 753

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           GP G  GSAG  GP G  GP G  G+ GP G  G  G A
Sbjct: 754 GPTGPIGSAGPSGPNGPPGPAGSRGDGGPPGATGFPGAA 792

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 38/100 (38%), Positives = 42/100 (42%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G+ G  G PG                    G  G PG  G  G AG 
Sbjct: 630 PGTAGASGPGGLPGERGAAGIPGGKGEKGETGLRGEIGNPGRDGARGAPGAMGAPGPAGA 689

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G  G+AG AG  GP G +G PG  G +GP G  G  G A
Sbjct: 690 TGDRGEAGPAGPAGPAGPRGTPGERGEVGPAGPNGFAGPA 729

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 41/99 (41%), Positives = 42/99 (42%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PG  G  G  G PG A                  G  G  G  G AG  G
Sbjct: 1010 EPGEKGPRGLPGLKGHNGLQGLPGLA---GQHGDQGAPGSVGPAGPRGPAGPSGPAGKDG 1066

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G PG  G AG  G +GSQGP GP G  GP G  GP G
Sbjct: 1067 RTGQPGTVGPAGIRGSQGSQGPAGPPGPPGPPGPPGPSG 1105

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 42/111 (37%), Positives = 50/111 (45%), Gaps = 12/111 (10%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG-- 412
           G  G+ G PG SG +G PG PG                  + G  G  G PG  G AG  
Sbjct: 280 GPRGEVGLPGVSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGAT 339

Query: 413 ----LIGPPGDAGSAGNDGPKG------SQGPPGPTGNIGPKGERGPKGVA 535
               ++G PG AGS G  G KG      +QGPPGP+G  G +G  G  G A
Sbjct: 340 GARGIVGEPGPAGSKGESGNKGEPGSAGAQGPPGPSGEEGKRGPNGEAGSA 390

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 41/98 (41%), Positives = 45/98 (45%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G MG  GPPG SG  G  GF G A                  G  G PG PG AG  G  
Sbjct: 94  GLMGPRGPPGASGAPGPQGFQGPAGEPGEPGQTGPA------GARGPPGPPGKAGEDGHP 147

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G PG  G  G  GP+G++G PG  G  G KG RG  G+
Sbjct: 148 GKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL 185

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 36/99 (36%), Positives = 42/99 (42%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  G  G +G  G  G PG                  + G  GEPG  G  G +G 
Sbjct: 300 PGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGIVGEPGPAGSKGESGN 359

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G PG AG+ G  GP G +G  GP G  G  G  GP G+
Sbjct: 360 KGEPGSAGAQGPPGPSGEEGKRGPNGEAGSAGPSGPPGL 398

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 40/99 (40%), Positives = 43/99 (43%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG +G  GP GP+G  G  G  G A                  G AG  G PG  GN G
Sbjct: 488 EPGNIGFPGPKGPTGDPGKNGDKGHA------------------GLAGARGAPGPDGNNG 529

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GPPG  G  G  G +G  GPPG  G  GP G  G  G
Sbjct: 530 AQGPPGPQGVQGGKGEQGPAGPPGFQGLPGPAGTAGEVG 568

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 38/98 (38%), Positives = 44/98 (44%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GP GP+G  G  G  G+                   G  G  G  G AG +G 
Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGTKGPKGEN---GPVGPTGPIGSAGPSGP 767

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG AGS G+ GP G+ G PG  G  GP G  G  G
Sbjct: 768 NGPPGPAGSRGDGGPPGATGFPGAAGRTGPPGPSGITG 805

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 38/104 (36%), Positives = 45/104 (43%), Gaps = 3/104 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ G  GP G+ G  G  G                  S GD G PG  G  G AG
Sbjct: 734  QPGAKGERGTKGPKGENGPVGPTGPIGSAGPSGPNGPPGPAGSRGDGGPPGATGFPGAAG 793

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPG---PTGNIGPKGERGPKGVA 535
              GPPG +G  G  GP G+ G  G   P G+ GP G  G  G +
Sbjct: 794  RTGPPGPSGITGPPGPPGAAGKEGLRGPRGDQGPVGRTGETGAS 837

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 41/108 (37%), Positives = 46/108 (42%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233 EPGRMGKD------GPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG  G+       GPPGP GK G+ G PG+                   G  G PG  G
Sbjct: 119 EPGEPGQTGPAGARGPPGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKG 178

Query: 395 VAGN---AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           + G+    GL G PG  G  G  G  G  G PG TG  G  GERG  G
Sbjct: 179 IRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVG 226

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 44/123 (35%), Positives = 51/123 (41%), Gaps = 24/123 (19%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG------DAGEPGDPG 394
           +PGR G+ G  GP G  G PG PG                    G      + G PG+ G
Sbjct: 149 KPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENG 208

Query: 395 VAGNAGL---------IGPPGDAGSAGND---------GPKGSQGPPGPTGNIGPKGERG 520
             G  G          +G PG AG+ G+D         GP GS GPPG  G  GPKGE G
Sbjct: 209 TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIG 268

Query: 521 PKG 529
           P G
Sbjct: 269 PVG 271

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 42/121 (34%), Positives = 50/121 (41%), Gaps = 22/121 (18%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN---- 406
           G  G+ GPPGP G+ GD G PG                    G  G PG PG+ GN    
Sbjct: 39  GPRGERGPPGPPGRDGDDGIPGPP------------------GPPGPPGPPGLGGNFAAQ 80

Query: 407 ------------AGLIGPPGDAGSAGNDGPKG------SQGPPGPTGNIGPKGERGPKGV 532
                        GL+GP G  G++G  GP+G        G PG TG  G +G  GP G 
Sbjct: 81  YDGKGVGLGPGPMGLMGPRGPPGASGAPGPQGFQGPAGEPGEPGQTGPAGARGPPGPPGK 140

Query: 533 A 535
           A
Sbjct: 141 A 141

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 38/97 (39%), Positives = 43/97 (44%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PG  G  G PG  G A                S G++G  G+PG AG  G  
Sbjct: 313 GLPGVAGAPGLPGPRGIPGPVGAAGATGARGIVGEPGPAGSKGESGNKGEPGSAGAQGPP 372

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G+ G  G +G  GS GP GP G  G  G RG  G
Sbjct: 373 GPSGEEGKRGPNGEAGSAGPSGPPGLRGSPGSRGLPG 409

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 36/98 (36%), Positives = 41/98 (41%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPG  G  G  G  G                    G  GE G PG +G AG  
Sbjct: 544 GEQGPAGPPGFQGLPGPAGTAGEVGKPGERGLPGEFGLPGPAGPRGERGPPGESGAAGPS 603

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           GP G  G +G  GP G++G PG  G  G  G  GP G+
Sbjct: 604 GPIGSRGPSGPPGPDGNKGEPGVLGAPGTAGASGPGGL 641

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 39/99 (39%), Positives = 43/99 (43%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP GP G+ G PG  G A                 IG  G  G PG  GN G 
Sbjct: 576 PGEFGLPGPAGPRGERGPPGESGAAGPSGP------------IGSRGPSGPPGPDGNKGE 623

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G  G  G+AG  GP G  G  G  G  G KGE+G  G+
Sbjct: 624 PGVLGAPGTAGASGPGGLPGERGAAGIPGGKGEKGETGL 662

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 37/99 (37%), Positives = 48/99 (48%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G+ G PGP+G  G+ G PG +                S G +G PG  G  G  G
Sbjct: 572 ERGLPGEFGLPGPAGPRGERGPPGES------GAAGPSGPIGSRGPSGPPGPDGNKGEPG 625

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           ++G PG AG++G  G  G +G  G  G  G KGE G +G
Sbjct: 626 VLGAPGTAGASGPGGLPGERGAAGIPGGKGEKGETGLRG 664

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 45/130 (34%), Positives = 49/130 (37%), Gaps = 33/130 (25%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
           G  G  G PG +G  G PG    PG                    G  GE G+ G  G+A
Sbjct: 307 GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGIVGEPGPAGSKGESGNKGEPGSA 366

Query: 410 GLIGPP------------GDAGSA------------------GNDGPKGSQGPPGPTGNI 499
           G  GPP            G+AGSA                  G DGP G  GPPGP G  
Sbjct: 367 GAQGPPGPSGEEGKRGPNGEAGSAGPSGPPGLRGSPGSRGLPGADGPAGVMGPPGPRGAT 426

Query: 500 GPKGERGPKG 529
           GP G RGP G
Sbjct: 427 GPAGVRGPNG 436

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 37/104 (35%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLG---DPGFPGRAXXXXXXXXXXXXXXXXSIG---DAGEPGDPGVA 400
            G  G DGPPG  G+ G   + G+PG                    G   + GEPG  G  
Sbjct: 928  GNPGNDGPPGRDGQAGHKGERGYPGNIGPVGAVGAPGPHGPVGPTGKHGNRGEPGPAGSV 987

Query: 401  GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G  G +GP G +G  G  G KG  G  GP G  G KG  G +G+
Sbjct: 988  GPVGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGL 1031

 Score = 37.7 bits (86), Expect = 0.092
 Identities = 21/50 (42%), Positives = 23/50 (46%)
 Frame = +2

Query: 383 GDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G  G  G  G  GPPG  G  G+DG  G  GPPGP          GP G+
Sbjct: 33  GPTGDRGPRGERGPPGPPGRDGDDGIPGPPGPPGPP---------GPPGL 73
>sp|P02467|CO1A2_CHICK Collagen alpha 2(I) chain precursor
          Length = 1362

 Score =  151 bits (381), Expect = 6e-36
 Identities = 119/421 (28%), Positives = 169/421 (40%), Gaps = 14/421 (3%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GP G  G  GDPG  G                    G+ GEPGD G  G  GL
Sbjct: 961  PGPHGQVGPSGKPGNRGDPGPVGPVGPAGAFGPRGLAGPQGPRGEKGEPGDKGHRGLPGL 1020

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXXXXXXXXXXXXXX 595
             G  G  G  G  G  G QGPPG  G  GP+G  GP G                      
Sbjct: 1021 KGHNGLQGLPGLAGQHGDQGPPGNNGPAGPRGPPGPSGPPGKDGRNGLPGPIGPAGVRGS 1080

Query: 596  XXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQAEQKSSIDPNDE 775
                                     ++  F       + E ++ D+P      S+ P D 
Sbjct: 1081 HGSQGPAGPPGPPGPPGPPGPNGGGYEVGF-------DAEYYRADQP------SLRPKDY 1127

Query: 776  DEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNGGHWKDAI 955
            + D    L  L+  ++ L  P GSK  PAR+C D++  +   S+G Y+IDPN G   DAI
Sbjct: 1128 EVDA--TLKTLNNQIETLLTPEGSKKNPARTCRDLRLSHPEWSSGFYWIDPNQGCTADAI 1185

Query: 956  YVFCNFEKLETCIEPEVSNY-KKTSYMKSHSS-----WFSILASLNKQVSY-------KI 1096
              +C+F   ETCI   + +   KT Y+  +       WF    +   Q  Y       K 
Sbjct: 1186 RAYCDFATGETCIHASLEDIPTKTWYVSKNPKDKKHIWFGETINGGTQFEYNGEGVTTKD 1245

Query: 1097 PKEQLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQILTVNNDD 1276
               QL F++L +   SQN T  C N    S   +++E        +L   N +      +
Sbjct: 1246 MATQLAFMRLLANHASQNITYHCKN----SIAYMDEETGNLKKAVILQGSNDVELRAEGN 1301

Query: 1277 DLFQYQIIEDNCKGKSSS-GRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIGVEIGPVC 1453
              F + ++ D C  K++  G+ +I+   ++P RLPI D     +  + Q + G+ IGPVC
Sbjct: 1302 SRFTFSVLVDGCSKKNNKWGKTIIEYRTNKPSRLPILDIAPLDIGGADQ-EFGLHIGPVC 1360

Query: 1454 F 1456
            F
Sbjct: 1361 F 1361

 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 47/101 (46%), Positives = 52/101 (51%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
           PG  G+ GP GP+G  G+PG   FPG                    G  GEPG PG  GN
Sbjct: 469 PGADGRVGPIGPAGNRGEPGNIGFPGPK------------------GPTGEPGKPGEKGN 510

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GL GP G  G  GN+   G+QGPPG TGN G KGE GP G
Sbjct: 511 VGLAGPRGAPGPEGNN---GAQGPPGVTGNQGAKGETGPAG 548

 Score = 80.9 bits (198), Expect = 9e-15
 Identities = 44/107 (41%), Positives = 54/107 (50%), Gaps = 6/107 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPG---PSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            EPG +G  GPPG   PSG +G PG    PG A                + G  GE G PG
Sbjct: 891  EPGPLGVSGPPGARGPSGPVGSPGPNGAPGEAGRDGNPGNDGPPGRDGAPGFKGERGAPG 950

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
              G +G +G PG  G  G  G  G++G PGP G +GP G  GP+G+A
Sbjct: 951  NPGPSGALGAPGPHGQVGPSGKPGNRGDPGPVGPVGPAGAFGPRGLA 997

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 42/100 (42%), Positives = 48/100 (48%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGP+G  G PG PG A                  G+ G  G PG AG  G 
Sbjct: 787  PGAAGRVGPPGPAGITGPPGPPGPAGKDGPRGLRGDVGPVGRTGEQGIAGPPGFAGEKGP 846

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G  G AG  G  GP+G  G PG  G  G +GERG  G+A
Sbjct: 847  SGEAGAAGPPGTPGPQGILGAPGILGLPGSRGERGLPGIA 886

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 43/110 (39%), Positives = 50/110 (45%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G+ GP GP G+ G  G  G                    GDAG PG  G  G AG
Sbjct: 732  QPGAKGERGPKGPKGETGPTGAIGPIGASGPPGPVGAAGPAGPRGDAGPPGMTGFPGAAG 791

Query: 413  LIGPPGDAG---------SAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             +GPPG AG          AG DGP+G +G  GP G  G +G  GP G A
Sbjct: 792  RVGPPGPAGITGPPGPPGPAGKDGPRGLRGDVGPVGRTGEQGIAGPPGFA 841

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 44/104 (42%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGF------PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
           PG  G  G PG  G+ G PG        GR                   GD GE G  G 
Sbjct: 640 PGERGVAGVPGGKGEKGAPGLRGDTGATGRDGARGLPGAIGAPGPAGGAGDRGEGGPAGP 699

Query: 398 AGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           AG AG  G PG+ G  G  GP G  GPPG  G  G KGERGPKG
Sbjct: 700 AGPAGARGIPGERGEPGPVGPSGFAGPPGAAGQPGAKGERGPKG 743

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/102 (41%), Positives = 50/102 (49%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           + G  G+DG  G  G +G PG  G A                + G  GE G+PG  G +G
Sbjct: 663 DTGATGRDGARGLPGAIGAPGPAGGAGDRGEGGPAGPAGPAGARGIPGERGEPGPVGPSG 722

Query: 413 LIGPPGDAG---SAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GPPG AG   + G  GPKG +G  GPTG IGP G  GP G
Sbjct: 723 FAGPPGAAGQPGAKGERGPKGPKGETGPTGAIGPIGASGPPG 764

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/100 (42%), Positives = 46/100 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GP GPSG  G PG  G+                   G  GE G  G  G  G 
Sbjct: 709 PGERGEPGPVGPSGFAGPPGAAGQPGAKGERGPK---------GPKGETGPTGAIGPIGA 759

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GPPG  G+AG  GP+G  GPPG TG  G  G  GP G A
Sbjct: 760 SGPPGPVGAAGPAGPRGDAGPPGMTGFPGAAGRVGPPGPA 799

 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 43/98 (43%), Positives = 45/98 (45%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG MG  GP GP G  G PG PG                    G  GEPG+PG  G  G 
Sbjct: 89  PGPMGLMGPRGPPGASGPPGPPGFQ------------------GVPGEPGEPGQTGPQGP 130

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG  G AG DG  G  G PG  G  GP+G RG  G
Sbjct: 131 RGPPGPPGKAGEDGHPGKPGRPGERGVAGPQGARGFPG 168

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 39/98 (39%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GPPGP+G  G  G  G                    G++G  G+PG AG  G 
Sbjct: 322 PGPRGIPGPPGPAGPSGARGLVGEPGPAGAK------------GESGNKGEPGAAGPPGP 369

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP G+ G  G++G  GS GPPGP G  G  G RG  G
Sbjct: 370 PGPSGEEGKRGSNGEPGSAGPPGPAGLRGEPGSRGLPG 407

 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 40/101 (39%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG---VAGN 406
            PG  GKDGP G  G +G  G  G                    G AG PG PG   + G 
Sbjct: 808  PGPAGKDGPRGLRGDVGPVGRTGEQGIAGPPGFAGEKGPSGEAGAAGPPGTPGPQGILGA 867

Query: 407  AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G++G PG  G  G  G  G+ G PGP G  GP G RGP G
Sbjct: 868  PGILGLPGSRGERGLPGIAGATGEPGPLGVSGPPGARGPSG 908

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 36/98 (36%), Positives = 45/98 (45%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G +G  GP G  G+ G  G                    G+AG+PG+ G+ G  G+
Sbjct: 520 PGPEGNNGAQGPPGVTGNQGAKGETGPAGPPGFQGLPGPSGPAGEAGKPGERGLHGEFGV 579

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP G  G  G  G  G+ GP GP G+ GP G  GP G
Sbjct: 580 PGPAGPRGERGLPGESGAVGPAGPIGSRGPSGPPGPDG 617

 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 38/97 (39%), Positives = 44/97 (45%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G+ GP GP G  G PG  G A                  G AG  G+ G+ G +G +
Sbjct: 539 GAKGETGPAGPPGFQGLPGPSGPAGEAGKPGERGLHGEFGVPGPAGPRGERGLPGESGAV 598

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  GS G  GP G  G  G  GN+GP G  GP G
Sbjct: 599 GPAGPIGSRGPSGPPGPDGNKGEPGNVGPAGAPGPAG 635

 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 40/102 (39%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G +GP GP+G  G+ G PG +                 +G  G PG  G+ G  G
Sbjct: 264 EIGPAGNEGPTGPAGPRGEIGLPGSSGP---------------VGPPGNPGANGLPGAKG 308

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPK---GERGPKG 529
             G PG AG+ G  GP+G  GPPGP G  G +   GE GP G
Sbjct: 309 AAGLPGVAGAPGLPGPRGIPGPPGPAGPSGARGLVGEPGPAG 350

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 40/99 (40%), Positives = 46/99 (46%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG +G  GP GP+G+ G PG  G                  ++G AG  G PG  GN G
Sbjct: 486 EPGNIGFPGPKGPTGEPGKPGEKG------------------NVGLAGPRGAPGPEGNNG 527

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GPPG  G+ G  G  G  GPPG  G  GP G  G  G
Sbjct: 528 AQGPPGVTGNQGAKGETGPAGPPGFQGLPGPSGPAGEAG 566

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 42/101 (41%), Positives = 44/101 (43%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
            PG +G  GP GP G  G PG   FPG A                  G  G PG PG AG 
Sbjct: 763  PGPVGAAGPAGPRGDAGPPGMTGFPGAAGRVGPPGPA---------GITGPPGPPGPAGK 813

Query: 407  AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G  G  GD G  G  G +G  GPPG  G  GP GE G  G
Sbjct: 814  DGPRGLRGDVGPVGRTGEQGIAGPPGFAGEKGPSGEAGAAG 854

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 40/99 (40%), Positives = 45/99 (45%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG  G  GPPGPSG+ G  G  G                    G AG PG  G+ G  G
Sbjct: 360 EPGAAGPPGPPGPSGEEGKRGSNGEP------------------GSAGPPGPAGLRGEPG 401

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G PG  G AG  GP G++G  GP G  GP G+ G  G
Sbjct: 402 SRGLPGADGRAGVMGPAGNRGASGPVGAKGPNGDAGRPG 440

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 40/107 (37%), Positives = 45/107 (42%), Gaps = 6/107 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G  GP GP G  G  G PG                    G  G PG  G +G  G
Sbjct: 282 EIGLPGSSGPVGPPGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPPGPAGPSGARG 341

Query: 413 LIGPPGDAGSAGNDGPKGSQG------PPGPTGNIGPKGERGPKGVA 535
           L+G PG AG+ G  G KG  G      PPGP+G  G +G  G  G A
Sbjct: 342 LVGEPGPAGAKGESGNKGEPGAAGPPGPPGPSGEEGKRGSNGEPGSA 388

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 40/99 (40%), Positives = 45/99 (45%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G+ GP G  G+ G+ G PG A                  G  GEPG  G  G AGL 
Sbjct: 341 GLVGEPGPAGAKGESGNKGEPGAAGPPGPPGPSGEEGKR---GSNGEPGSAGPPGPAGLR 397

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G PG  G  G DG  G  GP G  G  GP G +GP G A
Sbjct: 398 GEPGSRGLPGADGRAGVMGPAGNRGASGPVGAKGPNGDA 436

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 40/102 (39%), Positives = 46/102 (45%), Gaps = 3/102 (2%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPGP G  G+PG  G A                  G+ G  G PG  G  G  
Sbjct: 605 GSRGPSGPPGPDGNKGEPGNVGPAGAPGPAGPGGIP------GERGVAGVPGGKGEKGAP 658

Query: 419 GPPGDAGSAGNDGPKG---SQGPPGPTGNIGPKGERGPKGVA 535
           G  GD G+ G DG +G   + G PGP G  G +GE GP G A
Sbjct: 659 GLRGDTGATGRDGARGLPGAIGAPGPAGGAGDRGEGGPAGPA 700

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 40/99 (40%), Positives = 46/99 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GPPG  G  G+PG PG+                   G  G PG PG AG  G 
Sbjct: 101 PGASGPPGPPGFQGVPGEPGEPGQTGPQ---------------GPRGPPGPPGKAGEDGH 145

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G PG  G  G  GP+G++G PG  G  G KG RG  G+
Sbjct: 146 PGKPGRPGERGVAGPQGARGFPGTPGPPGFKGIRGHNGL 184

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 39/106 (36%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGR--------AXXXXXXXXXXXXXXXXSIGDAGEPGDP 391
           PGR G+DGPPGP G  G PG  G                            G +G PG P
Sbjct: 51  PGRDGEDGPPGPPGPPGPPGLGGNFAAQYDPSKAADFGPGPMGLMGPRGPPGASGPPGPP 110

Query: 392 GVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G        G PG+ G  G  GP+G +GPPGP G  G  G  G  G
Sbjct: 111 GFQ------GVPGEPGEPGQTGPQGPRGPPGPPGKAGEDGHPGKPG 150

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 44/108 (40%), Positives = 46/108 (42%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G  G PGP G LG PG  G                    G  GEPG  GV+G  G
Sbjct: 849  EAGAAGPPGTPGPQGILGAPGILGLPGSRGERGLPGIA------GATGEPGPLGVSGPPG 902

Query: 413  LIGPPGDAGS---------AGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GP G  GS         AG DG  G+ GPPG  G  G KGERG  G
Sbjct: 903  ARGPSGPVGSPGPNGAPGEAGRDGNPGNDGPPGRDGAPGFKGERGAPG 950

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 38/99 (38%), Positives = 44/99 (44%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP GP+G+ G PG  G                    G++G  G  G  G+ G 
Sbjct: 550 PGFQGLPGPSGPAGEAGKPGERGLHGEFGVPGPAGPRGERGLPGESGAVGPAGPIGSRGP 609

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            GPPG  G+ G  G  G  G PGP G  G  GERG  GV
Sbjct: 610 SGPPGPDGNKGEPGNVGPAGAPGPAGPGGIPGERGVAGV 648

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 40/105 (38%), Positives = 46/105 (43%), Gaps = 6/105 (5%)
 Frame = +2

Query: 233 EPGRMGKDGP---PGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
           EPG+ G  GP   PGP GK G+ G PG+                   G  G PG  G+ G
Sbjct: 121 EPGQTGPQGPRGPPGPPGKAGEDGHPGKPGRPGERGVAGPQGARGFPGTPGPPGFKGIRG 180

Query: 404 N---AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           +    GL G PG  G+ G  G  G  G PG  G  G  GERG  G
Sbjct: 181 HNGLDGLTGQPGAPGTKGEPGAPGENGTPGQPGARGLPGERGRIG 225

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 36/98 (36%), Positives = 44/98 (44%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GP G +G  G PG PG                  + G  G PG  G  G  G+
Sbjct: 838  PGFAGEKGPSGEAGAAGPPGTPG------------PQGILGAPGILGLPGSRGERGLPGI 885

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             G  G+ G  G  GP G++GP GP G+ GP G  G  G
Sbjct: 886  AGATGEPGPLGVSGPPGARGPSGPVGSPGPNGAPGEAG 923

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 36/97 (37%), Positives = 40/97 (41%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPGP G  G PG PG                    G+ G PG PG  G  G+ 
Sbjct: 99  GPPGASGPPGPPGFQGVPGEPGEPGQTGPQGPRGPPGPPGKAGEDGHPGKPGRPGERGVA 158

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  G  G  GP G +G  G  G  G  G+ G  G
Sbjct: 159 GPQGARGFPGTPGPPGFKGIRGHNGLDGLTGQPGAPG 195

 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 39/99 (39%), Positives = 42/99 (42%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  G PGPSG  G+ G PG                    G  GE G  G AG  G  
Sbjct: 548 GPPGFQGLPGPSGPAGEAGKPGERGLHGEFGVPGPAGPRGERGLPGESGAVGPAGPIGSR 607

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           GP G  G  GN G  G+ GP G  G  GP G  G +GVA
Sbjct: 608 GPSGPPGPDGNKGEPGNVGPAGAPGPAGPGGIPGERGVA 646

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 36/100 (36%), Positives = 41/100 (41%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG+ G+ G  G +G  G  GFPG                    G  G PG  G  G  G 
Sbjct: 146 PGKPGRPGERGVAGPQGARGFPGTPGPPGFKGIRGHNGLDGLTGQPGAPGTKGEPGAPGE 205

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G PG  G+ G  G +G  G PGP G  G  G  GP G A
Sbjct: 206 NGTPGQPGARGLPGERGRIGAPGPAGARGSDGSAGPTGPA 245

 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 43/132 (32%), Positives = 52/132 (39%), Gaps = 33/132 (25%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIG------DAGEPGDP 391
           G  G  GPPGP+G  G+PG    PG                   +G      DAG PG+P
Sbjct: 383 GEPGSAGPPGPAGLRGEPGSRGLPGADGRAGVMGPAGNRGASGPVGAKGPNGDAGRPGEP 442

Query: 392 GVAGNA------------------------GLIGPPGDAGSAGNDGPKGSQGPPGPTGNI 499
           G+ G                          G +GP G AG+ G  G  G  GP GPTG  
Sbjct: 443 GLMGPRXXXXXXXXXXXXXXXXXXGFPGADGRVGPIGPAGNRGEPGNIGFPGPKGPTGEP 502

Query: 500 GPKGERGPKGVA 535
           G  GE+G  G+A
Sbjct: 503 GKPGEKGNVGLA 514

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 52/100 (52%), Positives = 60/100 (60%), Gaps = 3/100 (3%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G +G  GP G +G+ G+PG  G                    G  G  G  G  G AG  
Sbjct: 425 GPVGAKGPNGDAGRPGEPGLMGPRXXXXXXXXXXXXXXXXXXGFPGADGRVGPIGPAGNR 484

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNI---GPKGERGPKG 529
           G PG+ G  G  GP G  G PG  GN+   GP+G  GP+G
Sbjct: 485 GEPGNIGFPGPKGPTGEPGKPGEKGNVGLAGPRGAPGPEG 524

 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 36/100 (36%), Positives = 41/100 (41%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G +G PG  G  G PG  G                    G  G  G+PG AG  G 
Sbjct: 295 PGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPPGPAGPSGARGLVGEPGPAGAKGE 354

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G  G+ G+AG  GP G  G  G  G+ G  G  GP G A
Sbjct: 355 SGNKGEPGAAGPPGPPGPSGEEGKRGSNGEPGSAGPPGPA 394

 Score = 60.8 bits (146), Expect = 1e-08
 Identities = 38/99 (38%), Positives = 44/99 (44%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G+ G PGP+G  G+ G PG +                 IG  G  G PG  GN G
Sbjct: 570 ERGLHGEFGVPGPAGPRGERGLPGESGAVGPAGP---------IGSRGPSGPPGPDGNKG 620

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
               PG+ G AG  GP G  G PG  G  G  G +G KG
Sbjct: 621 ---EPGNVGPAGAPGPAGPGGIPGERGVAGVPGGKGEKG 656

 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 40/102 (39%), Positives = 40/102 (39%), Gaps = 6/102 (5%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            EPG  G  G PG  G  G  G PG A                  G  G  G PG  G  G
Sbjct: 1008 EPGDKGHRGLPGLKGHNGLQGLPGLAGQHGDQGPPGNNGPAGPRGPPGPSGPPGKDGRNG 1067

Query: 413  LIGPPGDAG------SAGNDGPKGSQGPPGPTGNIGPKGERG 520
            L GP G AG      S G  GP G  GPPGP G  G   E G
Sbjct: 1068 LPGPIGPAGVRGSHGSQGPAGPPGPPGPPGPPGPNGGGYEVG 1109

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 49/100 (49%), Positives = 53/100 (53%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ G PGP+G  G  G  G                       GE G  G  G  G 
Sbjct: 218 PGERGRIGAPGPAGARGSDGSAGPTGPAXXXXXXXXXXXXXXXXX-GEIGPAGNEGPTGP 276

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GP G+ G  G+ GP G  G PG  G  G KG  G  GVA
Sbjct: 277 AGPRGEIGLPGSSGPVGPPGNPGANGLPGAKGAAGLPGVA 316

 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 20/119 (16%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRA-----------XXXXXXXXXXXXXXXXSIGDAGE 379
           E GR+G  GP G  G  G  G  G A                             G AG 
Sbjct: 220 ERGRIGAPGPAGARGSDGSAGPTGPAXXXXXXXXXXXXXXXXXGEIGPAGNEGPTGPAGP 279

Query: 380 PGDPGVAGNAGLIGPPGDAGSAGNDGPK---------GSQGPPGPTGNIGPKGERGPKG 529
            G+ G+ G++G +GPPG+ G+ G  G K         G+ G PGP G  GP G  GP G
Sbjct: 280 RGEIGLPGSSGPVGPPGNPGANGLPGAKGAAGLPGVAGAPGLPGPRGIPGPPGPAGPSG 338

 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 29/74 (39%), Positives = 30/74 (40%), Gaps = 17/74 (22%)
 Frame = +2

Query: 359 SIGDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTG--------------- 493
           S   AG  G  G  G  G  GPPG  G  G DGP G  GPPGP G               
Sbjct: 26  SEASAGRKGPRGDKGPQGERGPPGPPGRDGEDGPPGPPGPPGPPGLGGNFAAQYDPSKAA 85

Query: 494 --NIGPKGERGPKG 529
               GP G  GP+G
Sbjct: 86  DFGPGPMGLMGPRG 99

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 20/43 (46%), Positives = 22/43 (51%)
 Frame = +2

Query: 404 NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +AG  GP GD G  G  GP G  G  G  G  GP G  GP G+
Sbjct: 29  SAGRKGPRGDKGPQGERGPPGPPGRDGEDGPPGPPGPPGPPGL 71
>sp|P28481|CO2A1_MOUSE Collagen alpha 1(II) chain precursor [Contains: Chondrocalcin]
          Length = 1459

 Score =  150 bits (379), Expect = 1e-35
 Identities = 117/432 (27%), Positives = 173/432 (40%), Gaps = 25/432 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGR------AXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
            PG  G  GP GP+GK GD G  G       +                  G++GE G+ G+
Sbjct: 1042 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIAGPQGPRGDKGESGEQGERGL 1101

Query: 398  AGNAG------LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVAXXXXXXXX 559
             G+ G      L GPPG +G  G  GP G  GP GP G +GP G+ G  G+         
Sbjct: 1102 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGSNGIPGPIGPPGP 1161

Query: 560  XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXNTDFQNIFKRQRTTDEEEQFQRDEPQ 739
                                               + F  + +R++  D  +  + DE  
Sbjct: 1162 RGRSGETGPVGPPGSPGPPGPPGPPGPGIDM----SAFAGLGQREKGPDPMQYMRADEAD 1217

Query: 740  AEQKSSIDPNDEDEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYY 919
            +  +        D ++   L  L+  ++++  P GS+  PAR+C D++  +    +G Y+
Sbjct: 1218 STLRQ------HDVEVDATLKSLNNQIESIRSPDGSRKNPARTCQDLKLCHPEWKSGDYW 1271

Query: 920  IDPNGGHWKDAIYVFCNFEKLETCIEPEVSNYKKTSYMKSHSS-----WFSILASLNKQV 1084
            IDPN G   DA+ VFCN E  ETC+ P  +   + ++  S S      WF    +     
Sbjct: 1272 IDPNQGCTLDAMKVFCNMETGETCVYPNPATVPRKNWWSSKSKEKKHIWFGETMNGGFHF 1331

Query: 1085 SY-------KIPKEQLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGD 1243
            SY            Q+ FL+L S   SQN T  C N     D +     K      L+  
Sbjct: 1332 SYGDGNLAPNTANVQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKK----ALLIQG 1387

Query: 1244 DNQILTVNNDDDLFQYQIIEDNC-KGKSSSGRVVIKVELDRPRRLPIRDFNFKSLESSPQ 1420
             N +      +  F Y  ++D C K     G+ VI+    +  RLPI D     +  + Q
Sbjct: 1388 SNDVEMRAEGNSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGAEQ 1447

Query: 1421 AKIGVEIGPVCF 1456
             + GV+IGPVCF
Sbjct: 1448 -EFGVDIGPVCF 1458

 Score = 82.4 bits (202), Expect = 3e-15
 Identities = 45/114 (39%), Positives = 53/114 (46%), Gaps = 15/114 (13%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G+ G  GPPGP G  G PGFPG                  + G  GEPG+PG  G AG  
Sbjct: 320 GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGSRGEPGNPGSPGPAGAS 379

Query: 419 GPPGD---------------AGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G PG                AG+ G  GP+G  GP G TG +GPKG+ G  G+A
Sbjct: 380 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQAGEPGIA 433

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 42/97 (43%), Positives = 47/97 (48%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G+ GPPGPSG  G  G PG                    G  G  G PG  G+ G  
Sbjct: 773  GEKGEAGPPGPSGSTGARGAPGEPGETGPPGPAGFA------GPPGADGQPGAKGDQGEA 826

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  GDAG+ G  GP G+ GP GPTG  GPKG RG +G
Sbjct: 827  GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 863

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 44/106 (41%), Positives = 51/106 (48%), Gaps = 6/106 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGR------AXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
           EPG  G  GPPG  G  G+ GFPG+                       + GD G PG+PG
Sbjct: 468 EPGGAGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG 527

Query: 395 VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           + G  GL G PGDAG  G  GP G+ G  G  G  GP+G RG  GV
Sbjct: 528 LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 573

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 41/98 (41%), Positives = 47/98 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GPPGP G  G PG  G                    G  G  G+PG AG  GL
Sbjct: 553 PGEDGRPGPPGPQGARGQPGVMGFP------------------GPKGANGEPGKAGEKGL 594

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G DG  G+ GPPGP+G  G +GE+G  G
Sbjct: 595 AGAPGLRGLPGKDGETGAAGPPGPSGPAGERGEQGAPG 632

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 45/105 (42%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPG  GK GD G PG A                  G+ G PG+ G  G  GL 
Sbjct: 638 GLPGPPGPPGEGGKQGDQGIPGEAGAPGLVGPR---------GERGFPGERGSPGAQGLQ 688

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGP------KGERGPKGVA 535
           GP G  G+ G DGPKG+ GP GP G  GP       GERG  G+A
Sbjct: 689 GPRGLPGTPGTDGPKGAAGPDGPPGAQGPPGLQGMPGERGAAGIA 733

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 42/111 (37%), Positives = 50/111 (45%), Gaps = 12/111 (10%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGP+G  G PG  G+                 + G  G  G PG  G  G+
Sbjct: 793  PGEPGETGPPGPAGFAGPPGADGQPGAKGDQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV 852

Query: 416  IGPPGDAGS------------AGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             GP G  G+            AG  GP G+ G PGP G  GP G+ GPKGV
Sbjct: 853  TGPKGARGAQGPPGATGFPGAAGRVGPPGANGNPGPAGPPGPAGKDGPKGV 903

 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 41/105 (39%), Positives = 47/105 (44%), Gaps = 6/105 (5%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G  GP GP G  G PG  G                   +G+ G  G PG  G  GL 
Sbjct: 701  GPKGAAGPDGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 760

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKG------ERGPKGVA 535
            GP G  G AG +G KG  GPPGP+G+ G +G      E GP G A
Sbjct: 761  GPIGPPGPAGANGEKGEAGPPGPSGSTGARGAPGEPGETGPPGPA 805

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 42/110 (38%), Positives = 46/110 (41%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236  PGRMGKDGPPGP------------SGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGE 379
            PG  G  GPPGP             G+ G PG  G                  ++G  G 
Sbjct: 982  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGALGAPGA 1041

Query: 380  PGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            PG PG  G AG  G  GD G AG  GP G  GP G  G  GP+G RG KG
Sbjct: 1042 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIAGPQGPRGDKG 1091

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 41/97 (42%), Positives = 46/97 (47%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G MG  GPPGP+G  G  GF G                     + GEPG+PGV+G  G  
Sbjct: 176 GPMGPRGPPGPAGAPGPQGFQG---------------------NPGEPGEPGVSGPMGPR 214

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GPPG AG  G+DG  G  G  G  G  GP G RG  G
Sbjct: 215 GPPGPAGKPGDDGEAGKPGKSGERGLPGPMGARGFPG 251

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 43/110 (39%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN--- 406
           PG  G  GP GP G+ G+PG  G                  + G AGE G  G  G    
Sbjct: 412 PGPQGATGPLGPKGQAGEPGIAGFKGDQGPKGETGPAGPQGAPGPAGEEGKRGARGEPGG 471

Query: 407 AGLIGPPGDAGSAGN---------DGPKGSQGPPGPTGNIGPKGERGPKG 529
           AG IGPPG+ G+ GN          GPKG+ G  GP+G  GPKG  G  G
Sbjct: 472 AGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 521

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 39/106 (36%), Positives = 47/106 (44%), Gaps = 9/106 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG----- 403
           G  G DG PG  G  G PG  G                   +G  G+ G+PG+AG     
Sbjct: 380 GNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQAGEPGIAGFKGDQ 439

Query: 404 ----NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                 G  GP G  G AG +G +G++G PG  G IGP GERG  G
Sbjct: 440 GPKGETGPAGPQGAPGPAGEEGKRGARGEPGGAGPIGPPGERGAPG 485

 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPG +G  G  G PG A                  G  G+ G PG AG+ GL
Sbjct: 871  PGAAGRVGPPGANGNPGPAGPPGPAGKDGPK------------GVRGDSGPPGRAGDPGL 918

Query: 416  IGP---PGDAGSAGNDGPKGSQGPPGPTGNIGPK------GERGPKG 529
             GP   PG+ G  G+DGP G  GPPGP G  G +      G+RG +G
Sbjct: 919  EGPAGAPGEKGEPGDDGPSGLDGPPGPQGLAGQRGIVGLPGQRGERG 965

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 42/110 (38%), Positives = 47/110 (42%), Gaps = 9/110 (8%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG  G  GP GP G  G PG  G A                + G  G PG PGV G+ G
Sbjct: 204 EPGVSGPMGPRGPPGPAGKPGDDGEAGKPGKSGERGLPGPMGARGFPGTPGLPGVKGHRG 263

Query: 413 L---------IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
                      G PG  G +G+ G  GS GP GP G  G +G  GP G A
Sbjct: 264 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 313

 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 41/104 (39%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPG------PSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
            PG  GKDGP G      P G+ GDPG  G A                  G  G PG  G+
Sbjct: 892  PGPAGKDGPKGVRGDSGPPGRAGDPGLEGPAGAPGEKGEPGDDGPS---GLDGPPGPQGL 948

Query: 398  AGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            AG  G++G PG  G  G  G  G  G PG  G  G  G+RGP G
Sbjct: 949  AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG 992

 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 40/98 (40%), Positives = 43/98 (43%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GPPGP G  G  G  G+A                  G AG  G PG AG  G 
Sbjct: 403 PGFPGPRGPPGPQGATGPLGPKGQAGEPGIAGFKGDQGPKGETGPAGPQGAPGPAGEEGK 462

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G  G+ G AG  GP G +G PG  G  G  G  GPKG
Sbjct: 463 RGARGEPGGAGPIGPPGERGAPGNRGFPGQDGLAGPKG 500

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 39/101 (38%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD---PGVAGN 406
           PG  G +G PG +G+ G  G PG                    G AGE G+   PG +G 
Sbjct: 577 PGPKGANGEPGKAGEKGLAGAPGLRGLPGKDGETGAAGPPGPSGPAGERGEQGAPGPSGF 636

Query: 407 AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GL GPPG  G  G  G +G  G  G  G +GP+GERG  G
Sbjct: 637 QGLPGPPGPPGEGGKQGDQGIPGEAGAPGLVGPRGERGFPG 677

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 41/102 (40%), Positives = 44/102 (43%), Gaps = 3/102 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG---DAGEPGDPGVAG 403
            E G+ G  G PGP G  G PG  G                  + G    AG  G PG  G
Sbjct: 825  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGANG 884

Query: 404  NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            N G  GPPG AG    DGPKG +G  GP G  G  G  GP G
Sbjct: 885  NPGPAGPPGPAGK---DGPKGVRGDSGPPGRAGDPGLEGPAG 923

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 45/123 (36%), Positives = 49/123 (39%), Gaps = 24/123 (19%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG---------DAGEPG 385
           +PG+ G+ G PGP G  G PG PG                    G           GE G
Sbjct: 231 KPGKSGERGLPGPMGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 290

Query: 386 DPGVAGNAGL------IGPPGDAGSAGNDGPKGSQGPPGPTGNI---------GPKGERG 520
            PG  G  GL       GP G AG+ GNDG  G  GPPGP G           G KGE G
Sbjct: 291 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 350

Query: 521 PKG 529
           P G
Sbjct: 351 PTG 353

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 41/107 (38%), Positives = 43/107 (40%), Gaps = 6/107 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG  G  GP G SG  G  G PG                    G  G  G  G  G  G
Sbjct: 366 EPGNPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 425

Query: 413 LIGPPGDAGSAGNDGPKGS------QGPPGPTGNIGPKGERGPKGVA 535
             G PG AG  G+ GPKG       QG PGP G  G +G RG  G A
Sbjct: 426 QAGEPGIAGFKGDQGPKGETGPAGPQGAPGPAGEEGKRGARGEPGGA 472

 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 40/108 (37%), Positives = 46/108 (42%), Gaps = 9/108 (8%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            + G  G DGPPGP G  G  G  G                    G +GEPG  G  G +G
Sbjct: 933  DDGPSGLDGPPGPQGLAGQRGIVGLPGQRGERGFPGLP------GPSGEPGKQGAPGASG 986

Query: 413  LIGPP---------GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              GPP         G AG  G +G  G+ GPPG  G  G KG+RG  G
Sbjct: 987  DRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 1034

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 39/99 (39%), Positives = 47/99 (47%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G++G PGP G  G PG  GR                   G AG  G+ G  G AG
Sbjct: 282 ESGSPGENGSPGPMGPRGLPGERGRTGPA---------------GAAGARGNDGQPGPAG 326

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
             GP G AG  G  G  G++G  GPTG  GP+G +G +G
Sbjct: 327 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGSRG 365

 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 44/125 (35%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN 406
            PG  G  G  GP G+ G PG    PG                    G AG  G PG  G 
Sbjct: 658  PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAAGPDGPPGAQGP 717

Query: 407  AGLIGPPGDAGSAGNDGPKGSQ------------------------GPPGPTGNIGPKGE 514
             GL G PG+ G+AG  GPKG +                        GPPGP G  G KGE
Sbjct: 718  PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGE 777

Query: 515  RGPKG 529
             GP G
Sbjct: 778  AGPPG 782

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 28/127 (22%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXS----------------- 361
           EPG + +DG PGP G+ G+PG PG                                    
Sbjct: 108 EPGDI-RDGAPGPRGRDGEPGTPGNPGPAGPPGPPGPPGLSAGNFAAQMAGGYDEKAGGA 166

Query: 362 -----------IGDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPK 508
                      +G  G PG  G  G  G  G PG+ G  G  GP G +GPPGP G  G  
Sbjct: 167 QMGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPAGKPGDD 226

Query: 509 GERGPKG 529
           GE G  G
Sbjct: 227 GEAGKPG 233

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 39/107 (36%), Positives = 44/107 (41%), Gaps = 6/107 (5%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G+ G PG  G  G  G PG                  + G  G  G PG  G AG
Sbjct: 672 ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAAGPDGPPGAQGPPGLQGMPGERGAAG 731

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPG------PTGNIGPKGERGPKGVA 535
           + GP GD G  G  GP+G+ G  G      P G  GP G  G KG A
Sbjct: 732 IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEA 778

 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 36/99 (36%), Positives = 43/99 (43%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            +PG  G  G PG  G+ GD G  G                    G  GE G PG+ G +G
Sbjct: 915  DPGLEGPAGAPGEKGEPGDDGPSGLDGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 974

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              G  G  G++G+ GP G  GPPG TG  G  G  G  G
Sbjct: 975  EPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPG 1013

 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 39/116 (33%), Positives = 43/116 (37%), Gaps = 16/116 (13%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFP----------------GRAXXXXXXXXXXXXXXXXSI 364
           EPG  G  GP GP G  G PG                  G A                  
Sbjct: 125 EPGTPGNPGPAGPPGPPGPPGLSAGNFAAQMAGGYDEKAGGAQMGVMQGPMGPMGPRGPP 184

Query: 365 GDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           G AG PG  G  GN G  G PG +G  G  GP G  G PG  G  G  G+ G +G+
Sbjct: 185 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPAGKPGDDGEAGKPGKSGERGL 240

 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 37/107 (34%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGD------PGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
            PG  G  G  GP G  GD       G PG+                 + G+ GE G PG 
Sbjct: 724  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEAGPPGP 783

Query: 398  AGNAGLIGPPGDAGSAGNDGPKGSQ---GPPGPTGNIGPKGERGPKG 529
            +G+ G  G PG+ G  G   P G     GPPG  G  G KG++G  G
Sbjct: 784  SGSTGARGAPGEPGETG---PPGPAGFAGPPGADGQPGAKGDQGEAG 827

 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 39/122 (31%), Positives = 47/122 (38%), Gaps = 21/122 (17%)
 Frame = +2

Query: 233  EPGRMGK---DGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAG 403
            EPGR G    DGPPG  G  G  G  G                    G  G+ GD G AG
Sbjct: 1005 EPGREGSPGADGPPGRDGAAGVKGDRGETGALGAPGAPGPPGSPGPAGPTGKQGDRGEAG 1064

Query: 404  NAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIG------------------PKGERGPKG 529
              G +GP G AG+ G  GP+G +G  G +G  G                  P G  G +G
Sbjct: 1065 AQGPMGPSGPAGARGIAGPQGPRGDKGESGEQGERGLKGHRGFTGLQGLPGPPGPSGDQG 1124

Query: 530  VA 535
             +
Sbjct: 1125 AS 1126

 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 31/91 (34%), Positives = 37/91 (40%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            + G  G  GP GP G  G                         +G +G+ G  G+ G  G
Sbjct: 1122 DQGASGPAGPSGPRGPPG------------------------PVGPSGKDGSNGIPGPIG 1157

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGP 505
              GP G +G  G  GP GS GPPGP G  GP
Sbjct: 1158 PPGPRGRSGETGPVGPPGSPGPPGPPGPPGP 1188

 Score = 44.3 bits (103), Expect = 0.001
 Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 30/88 (34%)
 Frame = +2

Query: 362 IGDAGEPGDPGVA--GNAGLIGPPGDAGSAGNDGPKGSQGPPGP---------------- 487
           +G  G+ G+PG    G  G  G  G+ G+ GN GP G  GPPGP                
Sbjct: 100 LGPKGQKGEPGDIRDGAPGPRGRDGEPGTPGNPGPAGPPGPPGPPGLSAGNFAAQMAGGY 159

Query: 488 ------------TGNIGPKGERGPKGVA 535
                        G +GP G RGP G A
Sbjct: 160 DEKAGGAQMGVMQGPMGPMGPRGPPGPA 187
>sp|P02457|CA11_CHICK Collagen alpha 1(I) chain precursor
          Length = 1453

 Score =  149 bits (375), Expect = 3e-35
 Identities = 119/428 (27%), Positives = 174/428 (40%), Gaps = 21/428 (4%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  GP GP+GK GD G  G A                  G  G+ G+ G  G+ G+
Sbjct: 1037 PGAPGAPGPVGPAGKNGDRGETGPAGPAGPPGPAGARGPAGPQGPRGDKGETGEQGDRGM 1096

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPK---GVAXXXXXXXXXXXXXXXXX 586
             G  G +G  G  GP G+ G  GP+G  GP G RGP    G A                 
Sbjct: 1097 KGHRGFSGLQGPPGPPGAPGEQGPSGASGPAGPRGPPGSAGAAGKDGLNGLPGPIGPPGP 1156

Query: 587  XXXXXXXXXXXXXXXXXXXXXXXXXNTDFQNIF----KRQRTTDEEEQFQRDEPQAEQKS 754
                                     +  F   F     +++  D    ++ D+    +  
Sbjct: 1157 RGRTGEVGPVGPPGPPGPPGPPGPPSGGFDFSFLPQPPQEKAHDGGRYYRADDANVMR-- 1214

Query: 755  SIDPNDEDEDIFEALLRLSTIVDNLFKPPGSKTYPARSCADIQRDYNNKSNGMYYIDPNG 934
                 D D ++   L  LS  ++N+  P G++  PAR+C D++  + +  +G Y+IDPN 
Sbjct: 1215 -----DRDLEVDTTLKSLSQQIENIRSPEGTRKNPARTCRDLKMCHGDWKSGEYWIDPNQ 1269

Query: 935  GHWKDAIYVFCNFEKLETCIEPEVSNYKKTSYMKSHSS------WFSILASLNKQVSY-- 1090
            G   DAI V+CN E  ETC+ P  +   + ++  S +       WF    S   Q  Y  
Sbjct: 1270 GCNLDAIKVYCNMETGETCVYPTQATIAQKNWYLSKNPKEKKHVWFGETMSDGFQFEYGG 1329

Query: 1091 --KIPKE---QLVFLQLSSESTSQNFTLSCDNIGLVSDNSVNQENKYNNSLQLLGDDNQI 1255
                P +   QL FL+L S   +QN T  C N     D+      K      LL   N+I
Sbjct: 1330 EGSNPADVAIQLTFLRLMSTEATQNVTYHCKNSVAYMDHDTGNLKK----ALLLQGANEI 1385

Query: 1256 LTVNNDDDLFQYQIIEDNCKGKSSS-GRVVIKVELDRPRRLPIRDFNFKSLESSPQAKIG 1432
                  +  F Y + ED C   + + G+ VI+ +  +  RLPI D     +  +P  + G
Sbjct: 1386 EIRAEGNSRFTYGVTEDGCTSHTGAWGKTVIEYKTTKTSRLPIIDLAPMDV-GAPDQEFG 1444

Query: 1433 VEIGPVCF 1456
            ++IGPVCF
Sbjct: 1445 IDIGPVCF 1452

 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 46/98 (46%), Positives = 50/98 (51%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G DG  GP G  G  G PG A                  G AGEPG PG     G 
Sbjct: 533 PGSPGPDGKTGPPGPAGQDGRPGPAGPPGARGQAGVMGFPGPKGAAGEPGKPG---ERGA 589

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG  G+AG DG  G+QGPPGPTG  G +GE+GP G
Sbjct: 590 PGPPGAVGAAGKDGEAGAQGPPGPTGPAGERGEQGPAG 627

 Score = 82.0 bits (201), Expect = 4e-15
 Identities = 41/98 (41%), Positives = 45/98 (45%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG MG  G  GP G+ G  G PG                    G AG PG PG  G  G 
Sbjct: 986  PGPMGPPGLAGPPGEAGREGAPGAEGAPGRDGAAGPKGDRGETGPAGPPGAPGAPGAPGP 1045

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            +GP G  G  G  GP G  GPPGP G  GP G +GP+G
Sbjct: 1046 VGPAGKNGDRGETGPAGPAGPPGPAGARGPAGPQGPRG 1083

 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 49/123 (39%), Positives = 55/123 (44%), Gaps = 24/123 (19%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG--- 394
           +PGR G+ GPPGP G  G PG    PG                    G  GEPG PG   
Sbjct: 226 KPGRPGQRGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGQPGPAGPKGEPGSPGENG 285

Query: 395 ---------VAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGP---------KGERG 520
                    + G  G  GP G AG+ GNDG  G+ GPPGPTG  GP         KGE G
Sbjct: 286 APGQMGPRGLPGERGRPGPSGPAGARGNDGAPGAAGPPGPTGPAGPPGFPGAAGAKGETG 345

Query: 521 PKG 529
           P+G
Sbjct: 346 PQG 348

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 45/98 (45%), Positives = 51/98 (52%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ GPPGPSG +G PG PG A                  G AG PG+PG AG  G 
Sbjct: 866  PGAAGRVGPPGPSGNIGLPGPPGPAGKZGSKGPRG------ETGPAGRPGEPGPAGPPG- 918

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
              PPG+ GS G DGP G+ G PGP G  G +G  G  G
Sbjct: 919  --PPGEKGSPGADGPIGAPGTPGPQGIAGQRGVVGLPG 954

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 44/104 (42%), Positives = 51/104 (49%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G  G PGP+G++G PG  G                    G AG  G PG +GN GL
Sbjct: 830  PGPAGPTGAPGPAGZVGAPGPKGARGSAGPPGATGFP------GAAGRVGPPGPSGNIGL 883

Query: 416  IGPPGDAGSAGNDGPKGSQGP------PGPTGNIGPKGERGPKG 529
             GPPG AG  G+ GP+G  GP      PGP G  GP GE+G  G
Sbjct: 884  PGPPGPAGKZGSKGPRGETGPAGRPGEPGPAGPPGPPGEKGSPG 927

 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 42/98 (42%), Positives = 46/98 (46%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+ GP GP+G  G+ G PG A                  G AG PG PG AG  G 
Sbjct: 296 PGERGRPGPSGPAGARGNDGAPGAAGPPGPT------------GPAGPPGFPGAAGAKGE 343

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GP G  GS G  G +G  GPPGP G  GP G  G  G
Sbjct: 344 TGPQGARGSEGPQGSRGEPGPPGPAGAAGPAGNPGADG 381

 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 45/112 (40%), Positives = 49/112 (43%), Gaps = 15/112 (13%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA--- 409
           G  G  GPPGP+G  G PGFPG A                  G  GEPG PG AG A   
Sbjct: 315 GAPGAAGPPGPTGPAGPPGFPGAAGAKGETGPQGARGSEGPQGSRGEPGPPGPAGAAGPA 374

Query: 410 ------------GLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
                       G  G PG AG+ G  G +G  GP GP+G  GPKG  G  G
Sbjct: 375 GNPGADGQPGAKGATGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGEPG 426

 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 41/99 (41%), Positives = 45/99 (45%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG  G  GP G  G  G  GFPG                  ++G  G PG+ G  G AG
Sbjct: 463 EPGPAGLPGPAGERGAPGSRGFPGADGIAGPKGPPGERGSPGAVGPKGSPGEAGRPGEAG 522

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           L G  G  GS G+ GP G  GPPGP G  G  G  GP G
Sbjct: 523 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPAGPPG 561

 Score = 77.8 bits (190), Expect = 8e-14
 Identities = 47/110 (42%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLG---------DPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGD 388
            PG  G+ GPPGP+G  G         +PG PG A                  GDAG  GD
Sbjct: 767  PGDKGEAGPPGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGETGDAGAKGD 826

Query: 389  PGVAGNAGLIGPPGDAGSAGNDGPKG---SQGPPGPTGNIGPKGERGPKG 529
             G  G AG  G PG AG  G  GPKG   S GPPG TG  G  G  GP G
Sbjct: 827  AGPPGPAGPTGAPGPAGZVGAPGPKGARGSAGPPGATGFPGAAGRVGPPG 876

 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 42/99 (42%), Positives = 49/99 (49%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GPPGP G  G  G PG                  + GDAG PG PG  G  GL
Sbjct: 671 PGERGVQGPPGPQGPRGANGAPGN---------------DGAKGDAGAPGAPGNEGPPGL 715

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
            G PG+ G+AG  G KG +G PGP G  G  G+ G +G+
Sbjct: 716 EGMPGERGAAGLPGAKGDRGDPGPKGADGAPGKDGLRGL 754

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 43/104 (41%), Positives = 45/104 (43%), Gaps = 6/104 (5%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPG------FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGV 397
            PG  G  G PG  G  GDPG       PG+                 + GD GE G PG 
Sbjct: 719  PGERGAAGLPGAKGDRGDPGPKGADGAPGKDGLRGLTGPIGPPGPAGAPGDKGEAGPPGP 778

Query: 398  AGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            AG  G  G PGD G  G  GP G  GPPG  G  G KGE G  G
Sbjct: 779  AGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGETGDAG 822

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 41/97 (42%), Positives = 47/97 (48%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPGP+G  G+ G  G A                  G+AG+PG+ GV GNAG  
Sbjct: 603 GEAGAQGPPGPTGPAGERGEQGPAGAPGFQGLPGPAGPP---GEAGKPGEQGVPGNAGAP 659

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  G  G  G +G QGPPGP G  G  G  G  G
Sbjct: 660 GPAGARGERGFPGERGVQGPPGPQGPRGANGAPGNDG 696

 Score = 74.7 bits (182), Expect = 7e-13
 Identities = 39/97 (40%), Positives = 44/97 (45%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G+ G  GP G +G  G PG PG A                 IG  G PG  G+AG  G++
Sbjct: 891  GKZGSKGPRGETGPAGRPGEPGPAGPPGPPGEKGSPGADGPIGAPGTPGPQGIAGQRGVV 950

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            G PG  G  G  G  G  G PG  G  G  GERGP G
Sbjct: 951  GLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 987

 Score = 74.3 bits (181), Expect = 9e-13
 Identities = 46/123 (37%), Positives = 52/123 (42%), Gaps = 24/123 (19%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPS------GKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPG 394
            + G  G  GP GP+      G  G+PG PG A                  GDAG  GD G
Sbjct: 769  DKGEAGPPGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGETGDAGAKGDAG 828

Query: 395  VAGNAGLIGPPGDAGSAGNDGPKGSQ------------------GPPGPTGNIGPKGERG 520
              G AG  G PG AG  G  GPKG++                  GPPGP+GNIG  G  G
Sbjct: 829  PPGPAGPTGAPGPAGZVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNIGLPGPPG 888

Query: 521  PKG 529
            P G
Sbjct: 889  PAG 891

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 38/99 (38%), Positives = 47/99 (47%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  GK GPPGP+G+ G PG  G                  + G+ G+PG+ G  G  G 
Sbjct: 536 PGPDGKTGPPGPAGQDGRPGPAGPPGARGQAGVMGFPGPKGAAGEPGKPGERGAPGPPGA 595

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +G  G  G AG  GP G  GP G  G  GP G  G +G+
Sbjct: 596 VGAAGKDGEAGAQGPPGPTGPAGERGEQGPAGAPGFQGL 634

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 42/103 (40%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           E G  G  G  GP G  G+PG PG A                + G  G PG  G  G  G
Sbjct: 343 ETGPQGARGSEGPQGSRGEPGPPGPAGAAGPAGNPGADGQPGAKGATGAPGIAGAPGFPG 402

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKGV 532
             GP G  G +G  GPKG+ G PG  GN    G KGE GP GV
Sbjct: 403 ARGPSGPQGPSGAPGPKGNSGEPGAPGNKGDTGAKGEPGPAGV 445

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 42/106 (39%), Positives = 49/106 (46%), Gaps = 9/106 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGF---PGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
           G  G DG PG  G  G PG    PG                    G++GEPG PG  G+ 
Sbjct: 375 GNPGADGQPGAKGATGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGEPGAPGNKGDT 434

Query: 410 GLIGPPGDA------GSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  G PG A      G AG +G +G++G PGP G  GP GERG  G
Sbjct: 435 GAKGEPGPAGVQGPPGPAGEEGKRGARGEPGPAGLPGPAGERGAPG 480

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 40/100 (40%), Positives = 48/100 (48%)
 Frame = +2

Query: 233 EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
           EPG+ G+ G PGP G +G  G  G A                  G AG PG  G+ G AG
Sbjct: 580 EPGKPGERGAPGPPGAVGAAGKDGEAGAQGPPGPTGPAGERGEQGPAGAPGFQGLPGPAG 639

Query: 413 LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
              PPG+AG  G  G  G+ G PGP G  G +G  G +GV
Sbjct: 640 ---PPGEAGKPGEQGVPGNAGAPGPAGARGERGFPGERGV 676

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 41/97 (42%), Positives = 46/97 (47%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
           G  G  GPPG +GK G+ G PG A                  G+ G PG+ GV G  G  
Sbjct: 633 GLPGPAGPPGEAGKPGEQGVPGNAGAPGPAGAR---------GERGFPGERGVQGPPGPQ 683

Query: 419 GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           GP G  G+ GNDG KG  G PG  GN GP G  G  G
Sbjct: 684 GPRGANGAPGNDGAKGDAGAPGAPGNEGPPGLEGMPG 720

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 41/103 (39%), Positives = 44/103 (42%), Gaps = 3/103 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  GP G  G  G PG  G                    G  G  G PG  GN+G 
Sbjct: 365 PGPAGAAGPAGNPGADGQPGAKGATGAPGIAGAPGFPGARGPSGPQGPSGAPGPKGNSGE 424

Query: 416 IGPPG---DAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G PG   D G+ G  GP G QGPPGP G  G +G RG  G A
Sbjct: 425 PGAPGNKGDTGAKGEPGPAGVQGPPGPAGEEGKRGARGEPGPA 467

 Score = 71.2 bits (173), Expect = 7e-12
 Identities = 39/97 (40%), Positives = 48/97 (49%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G+ GP GP G  G PG PG                   +G AG+ GD G  G AG  
Sbjct: 1023 GDRGETGPAGPPGAPGAPGAPG------------------PVGPAGKNGDRGETGPAGPA 1064

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
            GPPG AG+ G  GP+G +G  G TG  G +G +G +G
Sbjct: 1065 GPPGPAGARGPAGPQGPRGDKGETGEQGDRGMKGHRG 1101

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 40/103 (38%), Positives = 43/103 (41%), Gaps = 6/103 (5%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIG------DAGEPGDPGVA 400
           G  G  GPPG  G  G PG PG                  S G          PG  G A
Sbjct: 114 GDRGLPGPPGRDGIPGQPGLPGPPGPPGPPGLGGNFAPQMSYGYDEKSAGVAVPGPMGPA 173

Query: 401 GNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           G  GL GPPG  G  G  GP G  G PG +G +GP+G  GP G
Sbjct: 174 GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPAGPPG 216

 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 40/107 (37%), Positives = 43/107 (40%), Gaps = 9/107 (8%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSI---------GDAGEPGD 388
           PGR G  G PG  G  G PG PG                   +         G  G PG 
Sbjct: 122 PGRDGIPGQPGLPGPPGPPGPPGLGGNFAPQMSYGYDEKSAGVAVPGPMGPAGPRGLPGP 181

Query: 389 PGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
           PG  G  G  GPPG+ G  G  GP G +GP GP G  G  GE G  G
Sbjct: 182 PGAPGPQGFQGPPGEPGEPGASGPMGPRGPAGPPGKNGDDGEAGKPG 228

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 41/110 (37%), Positives = 47/110 (42%), Gaps = 12/110 (10%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDP-------- 391
           PG  G  GP G  G  G+PG PG +                  G+AG+PG P        
Sbjct: 179 PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPAGPPGKNGDDGEAGKPGRPGQRGPPGP 238

Query: 392 ----GVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKG 529
               G+ G AGL G  G  G +G DG KG  GP GP G  G  GE G  G
Sbjct: 239 QGARGLPGTAGLPGMKGHRGFSGLDGAKGQPGPAGPKGEPGSPGENGAPG 288

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 40/99 (40%), Positives = 49/99 (49%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G+ G  G PG  G+ G PG PG +                  G +GE G PG  G  GL 
Sbjct: 945  GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPS---------GASGERGPPGPMGPPGLA 995

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GPPG+   AG +G  G++G PG  G  GPKG+RG  G A
Sbjct: 996  GPPGE---AGREGAPGAEGAPGRDGAAGPKGDRGETGPA 1031

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 39/96 (40%), Positives = 43/96 (44%)
 Frame = +2

Query: 248 GKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLIGPP 427
           G  GP GP G  G PG PG                    G  GEPG+PG +G  G  GP 
Sbjct: 168 GPMGPAGPRGLPGPPGAPGPQGFQ---------------GPPGEPGEPGASGPMGPRGPA 212

Query: 428 GDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G  G  G+DG  G  G PG  G  GP+G RG  G A
Sbjct: 213 GPPGKNGDDGEAGKPGRPGQRGPPGPQGARGLPGTA 248

 Score = 68.2 bits (165), Expect = 6e-11
 Identities = 39/101 (38%), Positives = 43/101 (42%), Gaps = 3/101 (2%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G  G PG  G  GD G  G                    G  GEPG  G+ G AG 
Sbjct: 416 PGPKGNSGEPGAPGNKGDTGAKGEPGPAGVQGPPGPAGEEGKRGARGEPGPAGLPGPAGE 475

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGN---IGPKGERGPKG 529
            G PG  G  G DG  G +GPPG  G+   +GPKG  G  G
Sbjct: 476 RGAPGSRGFPGADGIAGPKGPPGERGSPGAVGPKGSPGEAG 516

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 40/108 (37%), Positives = 48/108 (44%), Gaps = 9/108 (8%)
 Frame = +2

Query: 239 GRMGKDGPPGPSGKLGDPG---FPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNA 409
           G  G+ GP GP G+ G PG    PG+                   G  G  G PG AG  
Sbjct: 264 GAKGQPGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGPSGPAGARGNDGAPGAAGPP 323

Query: 410 GLIGP------PGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
           G  GP      PG AG+ G  GP+G++G  GP G+ G  G  GP G A
Sbjct: 324 GPTGPAGPPGFPGAAGAKGETGPQGARGSEGPQGSRGEPGPPGPAGAA 371

 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 39/100 (39%), Positives = 44/100 (44%)
 Frame = +2

Query: 236  PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
            PG  G+ G  GPSG  G+ G PG                  + G  G PG  G AG  G 
Sbjct: 965  PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGEAGREGAPGAEGAPGRDGAAGPKGD 1024

Query: 416  IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
             G  G AG  G  G  G+ GP GP G  G +GE GP G A
Sbjct: 1025 RGETGPAGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPA 1064

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 37/99 (37%), Positives = 43/99 (43%)
 Frame = +2

Query: 239  GRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGLI 418
            G  G+ GPPGP G  G  G PG A                + G  G+ G+ G AG  G  
Sbjct: 978  GASGERGPPGPMGPPGLAGPPGEAGREGAPGAEGAPGRDGAAGPKGDRGETGPAGPPGAP 1037

Query: 419  GPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            G PG  G  G  G  G +G  GP G  GP G  G +G A
Sbjct: 1038 GAPGAPGPVGPAGKNGDRGETGPAGPAGPPGPAGARGPA 1076

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 39/103 (37%), Positives = 47/103 (45%), Gaps = 3/103 (2%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGN-- 406
            E G  G  GPPGP+G  G  G  G                    G+ GE GD G+ G+  
Sbjct: 1057 ETGPAGPAGPPGPAGARGPAGPQG---------------PRGDKGETGEQGDRGMKGHRG 1101

Query: 407  -AGLIGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGV 532
             +GL GPPG  G+ G  GP G+ GP GP G  G  G  G  G+
Sbjct: 1102 FSGLQGPPGPPGAPGEQGPSGASGPAGPRGPPGSAGAAGKDGL 1144

 Score = 65.1 bits (157), Expect = 5e-10
 Identities = 39/100 (39%), Positives = 42/100 (42%)
 Frame = +2

Query: 236 PGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAGL 415
           PG  G+DG PG  G  G PG PG                         PG  G AG  GL
Sbjct: 119 PGPPGRDGIPGQPGLPGPPGPPGPPGLGGNFAPQMSYGYDEKSAGVAVPGPMGPAGPRGL 178

Query: 416 IGPPGDAGSAGNDGPKGSQGPPGPTGNIGPKGERGPKGVA 535
            GPPG  G      P+G QGPPG  G  G  G  GP+G A
Sbjct: 179 PGPPGAPG------PQGFQGPPGEPGEPGASGPMGPRGPA 212

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 37/91 (40%), Positives = 38/91 (41%)
 Frame = +2

Query: 233  EPGRMGKDGPPGPSGKLGDPGFPGRAXXXXXXXXXXXXXXXXSIGDAGEPGDPGVAGNAG 412
            E G  G  G  G SG  G PG PG                    G AG  G  G+ G  G
Sbjct: 1090 EQGDRGMKGHRGFSGLQGPPGPPGAPGEQGPSGASGPAGPRGPPGSAGAAGKDGLNGLPG 1149

Query: 413  LIGPPGDAGSAGNDGPKGSQGPPGPTGNIGP 505
             IGPPG  G  G  GP G  GPPGP G  GP
Sbjct: 1150 PIGPPGPRGRTGEVGPVGPPGPPGPPGPPGP 1180

 Score = 47.4 bits (111), Expect = 1e-04
 Identities = 26/57 (45%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
 Frame = +2

Query: 359 SIGDAGEPGDPGVAGNAGLIGPPGDAGSAGNDGPKGSQGPPGPT---GNIGPKGERG 520
           S G  G  GD G  G+ GL GPPG  G  G  G  G  GPPGP    GN  P+   G
Sbjct: 100 SAGVEGPKGDTGPRGDRGLPGPPGRDGIPGQPGLPGPPGPPGPPGLGGNFAPQMSYG 156

 Score = 40.8 bits (94), Expect = 0.011
 Identities = 21/46 (45%), Positives = 25/46 (54%), Gaps = 3/46 (6%)
 Frame = +2

Query: 404 NAGLIGPPGDAGSAGN---DGPKGSQGPPGPTGNIGPKGERGPKGV 532
           +AG+ GP GD G  G+    GP G  G PG  G  GP G  GP G+
Sbjct: 100 SAGVEGPKGDTGPRGDRGLPGPPGRDGIPGQPGLPGPPGPPGPPGL 145
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 154,106,673
Number of Sequences: 369166
Number of extensions: 3129829
Number of successful extensions: 51197
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 10454
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 21421
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 18891292455
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00427

  1. Dr_sW_011_F03
  2. Dr_sW_027_G07
  3. Dr_sW_001_I24