Planaria EST Database

DrC_00421

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00421
         (703 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q9Y794|ORC4_SCHPO  Origin recognition complex subunit 4         44   3e-04
sp|Q9U7E0|ATRX_CAEEL  Transcriptional regulator ATRX homolog...    42   0.002
sp|P40631|MLH_TETTH  Micronuclear linker histone polyprotein...    40   0.008
sp|P22058|CPD1_DROME  Chromosomal protein D1                       40   0.008
sp|Q8WXA9|SFR12_HUMAN  Splicing factor, arginine/serine-rich...    38   0.023
sp|P14196|AAC2_DICDI  AAC-rich mRNA clone AAC11 protein            36   0.086
sp|O01761|UNC89_CAEEL  Muscle M-line assembly protein unc-89...    36   0.11 
sp|Q8BRH4|MLL3_MOUSE  Myeloid/lymphoid or mixed-lineage leuk...    36   0.11 
sp|P49711|CTCF_HUMAN  Transcriptional repressor CTCF (CCCTC-...    35   0.19 
sp|P17096|HMGIY_HUMAN  High mobility group protein HMG-I/HMG...    35   0.19 

>sp|Q9Y794|ORC4_SCHPO Origin recognition complex subunit 4
          Length = 972

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 48/182 (26%), Positives = 77/182 (42%), Gaps = 29/182 (15%)
 Frame = +1

Query: 70  EIREKKFRGRPRKTVLDDEKSSLSNGEP-----QAKKSRGRPKKYTMQEDM-NTPSS--- 222
           E++ K+ RGRPRK +  +E SS  NG        AK+ RGRP  +  ++ + NTP S   
Sbjct: 197 ELKPKRGRGRPRK-IKPEEGSSSQNGLSPLVVLPAKRGRGRPPLHRSEQKIANTPISNNV 255

Query: 223 -VKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEK---------QDNEIVVKKHKGR 372
            V+ +  N+                       +E  ++            ++ VK+ +GR
Sbjct: 256 TVESTGTNLHTHSQLNPENEQSSSEFYSLNPQSEIRKEVVVTDQPLFSTADVPVKRKRGR 315

Query: 373 P---------SKSQKNEID-NKDKKPRGRPKSNLVSEMHKDASETTNNYDSVVVKSRERP 522
           P           S +N+ID N+ K+ RGRP+    S +  D+        S+  + R RP
Sbjct: 316 PPLNKPKILFGTSTENKIDENRPKRGRGRPRLERPSGLPLDSKS-----QSLFKRKRGRP 370

Query: 523 KK 528
            K
Sbjct: 371 PK 372


 Score = 30.4 bits (67), Expect = 4.7
 Identities = 23/100 (23%), Positives = 39/100 (39%), Gaps = 27/100 (27%)
 Frame = +1

Query: 7   RKSRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQ---------- 156
           ++ RGRP K+     S+     ++ K+ RGRPR   L   + S+  G  Q          
Sbjct: 123 KRKRGRPPKIKSSSPSTKLDDPLKPKRGRGRPRLHPLPVVQPSVDEGTTQNNLQMGLDEP 182

Query: 157 -----------------AKKSRGRPKKYTMQEDMNTPSSV 225
                             K+ RGRP+K   +E  ++ + +
Sbjct: 183 NIIEGFAEGHANLSELKPKRGRGRPRKIKPEEGSSSQNGL 222

>sp|Q9U7E0|ATRX_CAEEL Transcriptional regulator ATRX homolog (X-linked nuclear protein 1)
          Length = 1359

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 47/191 (24%), Positives = 81/191 (42%), Gaps = 15/191 (7%)
 Frame = +1

Query: 7   RKSRGRPRKLFV-DDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPK 183
           +KS+ + +K+   +  S D APE ++ + R R + +  +  +S  S+ E + K+S  +PK
Sbjct: 219 KKSKKKSKKVVKKESESEDEAPEKKKTEKRKRSKTSSEESSESEKSDEEEEEKESSPKPK 278

Query: 184 KYTMQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKH 363
           K         P +VK+ +                         S E SE+ D E++ +K 
Sbjct: 279 K-------KKPLAVKKLS-------------------------SDEESEESDVEVLPQKK 306

Query: 364 K------------GRPSKSQKNEIDNKDKKPRGRPKSNLVSEMHKDASE--TTNNYDSVV 501
           K             +  KS+    D ++K  + + K    SE   D+SE   T N  S  
Sbjct: 307 KRGAVTLISDSEDEKDQKSESEASDVEEKVSKKKAKKQESSESGSDSSEGSITVNRKS-- 364

Query: 502 VKSRERPKKSK 534
            K +E+P+K K
Sbjct: 365 -KKKEKPEKKK 374

>sp|P40631|MLH_TETTH Micronuclear linker histone polyprotein (MIC LH) [Contains:
           Micronuclear linker histone-alpha; Micronuclear linker
           histone-beta; Micronuclear linker histone-delta;
           Micronuclear linker histone-gamma]
          Length = 633

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 39/185 (21%), Positives = 67/185 (36%), Gaps = 1/185 (0%)
 Frame = +1

Query: 7   RKSRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPKK 186
           +KSR    K     ++++ +     K       K+    +  S S G+    +S  +PK 
Sbjct: 389 KKSRRNSMKEARTKKANNKSASKASKSGSKSKGKSASKSKGKSSSKGKNSKSRSASKPKS 448

Query: 187 YTMQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKHK 366
              Q   NT  +  +S++N                    T   T   +++  ++V +K  
Sbjct: 449 NAAQNSNNTHQTA-DSSENASST----------------TQTRTRGRQREQKDMVNEKSN 491

Query: 367 GRPS-KSQKNEIDNKDKKPRGRPKSNLVSEMHKDASETTNNYDSVVVKSRERPKKSKIPE 543
            + S K +KN   N   K + +  S       K   +TTN+      KSR   K      
Sbjct: 492 SKSSSKGKKNSKSNTRSKSKSKSASKSRKNASKSKKDTTNHGRQTRSKSRSESKSKSEAP 551

Query: 544 NELSN 558
           N+ SN
Sbjct: 552 NKPSN 556


 Score = 35.4 bits (80), Expect = 0.15
 Identities = 32/180 (17%), Positives = 62/180 (34%), Gaps = 6/180 (3%)
 Frame = +1

Query: 13  SRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPKKYT 192
           S+GR +      R+  +A + R +      RK     ++    +   +A  S+GR    +
Sbjct: 197 SKGRTKSTSSKRRADSSASQGRSQSSSSNRRKASSSKDQKGTRSSSRKASNSKGRKNSTS 256

Query: 193 MQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKH--- 363
            + + ++ S    S+ N K                  +    +AS  ++ +    K    
Sbjct: 257 NKRNSSSSSKRSSSSKNKKSSSSKNKKSSSSKGRKSSSSRGRKASSSKNRKSSKSKDRKS 316

Query: 364 ---KGRPSKSQKNEIDNKDKKPRGRPKSNLVSEMHKDASETTNNYDSVVVKSRERPKKSK 534
              KGR S S       K    RGR  S+        + E  N++     +  +  +K +
Sbjct: 317 SSSKGRKSSSSSKSNKRKASSSRGRKSSSSKGRKSSKSQERKNSHADTSKQMEDEGQKRR 376

>sp|P22058|CPD1_DROME Chromosomal protein D1
          Length = 355

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 30/120 (25%), Positives = 47/120 (39%), Gaps = 3/120 (2%)
 Frame = +1

Query: 94  GRPRKTVLDDEKSSLSNGEPQAKKSRGRPKKYTMQEDMNT---PSSVKESNDNVKQXXXX 264
           GRP+K  ++    S  +GEPQ  K RGRP +       +T   P+               
Sbjct: 177 GRPKKRAVE----SNGDGEPQVPKKRGRPPQNKSGSGGSTGYVPTGRPRGRPKANAAPVE 232

Query: 265 XXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKHKGRPSKSQKNEIDNKDKKPRGRPKSNL 444
                        +G+   +S ++   +V  K +GRPS +       +  KPR RP  N+
Sbjct: 233 KHEDNDDDQDDENSGEEEHSSPEKT--VVAPKKRGRPSLAAGKVSKEETTKPRSRPAKNI 290


 Score = 39.3 bits (90), Expect = 0.010
 Identities = 56/219 (25%), Positives = 84/219 (38%), Gaps = 44/219 (20%)
 Frame = +1

Query: 10  KSRGRPRKLFVDDRSSDTA-----PEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRG 174
           K RGRP K  V  +SS  A     P I++   RGRP K    ++ SS   G+      RG
Sbjct: 7   KKRGRPSKASVGGKSSTAAVAAISPGIKK---RGRPAK----NKGSSGGGGQ------RG 53

Query: 175 RPKKYTMQEDMNTP------------SSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDS- 315
           RP K +  ++   P            S  + +N++                    +GDS 
Sbjct: 54  RPPKASKIQNDEDPEDEGEEDGDGDGSGAELANNSSPSPTKGRGRPKSSGGAGSGSGDSV 113

Query: 316 -TEASEKQDNEIVVKKHKGRPSKSQKNEIDNKD--------------KKPRGRPKSNLVS 450
            T  S K       K+  GRP K Q ++ +N+D              ++P GRP +  V+
Sbjct: 114 KTPGSAK-------KRKAGRPKKHQPSDSENEDDQDEDDDGNSSIEERRPVGRPSAGSVN 166

Query: 451 -----------EMHKDASETTNNYDSVVVKSRERPKKSK 534
                         K A E+  + +  V K R RP ++K
Sbjct: 167 LNISRTGRGLGRPKKRAVESNGDGEPQVPKKRGRPPQNK 205


 Score = 35.4 bits (80), Expect = 0.15
 Identities = 38/153 (24%), Positives = 62/153 (40%), Gaps = 16/153 (10%)
 Frame = +1

Query: 85  KFRGRPRKTVLDDEKSSLSNGEPQAKKSR--GRPKKYTMQEDMNTPSSVKESNDNV---K 249
           K RGRP+ +      S  S   P + K R  GRPKK+   +  N     ++ + N    +
Sbjct: 94  KGRGRPKSSGGAGSGSGDSVKTPGSAKKRKAGRPKKHQPSDSENEDDQDEDDDGNSSIEE 153

Query: 250 QXXXXXXXXXXXXXXXXXTGDSTEASEKQ------DNEIVVKKHKGRPSKSQKNEIDNKD 411
           +                 TG      +K+      D E  V K +GRP +++     +  
Sbjct: 154 RRPVGRPSAGSVNLNISRTGRGLGRPKKRAVESNGDGEPQVPKKRGRPPQNKSGSGGSTG 213

Query: 412 K----KPRGRPKSNLVS-EMHKDASETTNNYDS 495
                +PRGRPK+N    E H+D  +  ++ +S
Sbjct: 214 YVPTGRPRGRPKANAAPVEKHEDNDDDQDDENS 246

>sp|Q8WXA9|SFR12_HUMAN Splicing factor, arginine/serine-rich 12 (Serine-arginine-rich
           splicing regulatory protein 86) (SRrp86) (Splicing
           regulatory protein 508) (SRrp508)
          Length = 508

 Score = 38.1 bits (87), Expect = 0.023
 Identities = 29/135 (21%), Positives = 49/135 (36%)
 Frame = +1

Query: 7   RKSRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPKK 186
           +KSR  PR      RS  ++ E R ++ R   R           S+  P  +    + KK
Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKK 418

Query: 187 YTMQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKHK 366
              + D  +    +E + ++++                   D  E  EK    +  K+H 
Sbjct: 419 REKERDHISERRERERSTSMRKSSNDR--------------DGKEKLEKNSTSLKEKEHN 464

Query: 367 GRPSKSQKNEIDNKD 411
             P  S   E+D+KD
Sbjct: 465 KEPDSSVSKEVDDKD 479


 Score = 33.9 bits (76), Expect = 0.43
 Identities = 40/176 (22%), Positives = 65/176 (36%)
 Frame = +1

Query: 7   RKSRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPKK 186
           RKSR R       D+  DT  +I+EK+     R    D EK      E + +K RG+ K 
Sbjct: 249 RKSRSRSHSR---DKRKDTREKIKEKE-----RVKEKDREKEREREKEREKEKERGKNKD 300

Query: 187 YTMQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKHK 366
              + + +     ++  +  ++                      E  ++QD E    K +
Sbjct: 301 RDKEREKDREKDKEKDREREREKEHEKDR-------------DKEKEKEQDKE----KER 343

Query: 367 GRPSKSQKNEIDNKDKKPRGRPKSNLVSEMHKDASETTNNYDSVVVKSRERPKKSK 534
            +    + +E   KDKK R  P+S   S   + +S       S    S   P+ SK
Sbjct: 344 EKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS--RSSSRSPRTSK 397

>sp|P14196|AAC2_DICDI AAC-rich mRNA clone AAC11 protein
          Length = 448

 Score = 36.2 bits (82), Expect = 0.086
 Identities = 40/178 (22%), Positives = 64/178 (35%), Gaps = 3/178 (1%)
 Frame = +1

Query: 34  LFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQAKKSRGRPKKYTMQEDMN- 210
           L ++   + ++    +K+ RGRPRK    + K +        K+ RGRP K  M E+ N 
Sbjct: 145 LGINSSPTQSSANSADKRSRGRPRKNPPSEPKDTSG-----PKRKRGRPPK--MDEEGNP 197

Query: 211 TPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNEIVVKKHKGRPSKSQK 390
            P  V +   N K+                   D    S    N     K +GRP K+  
Sbjct: 198 QPKPVPQPGSNKKR-------GRPKKPKDENESDYNNTSFSDSNTDGTPKKRGRPPKA-- 248

Query: 391 NEIDNKDKKPRGRPKSNLVSE--MHKDASETTNNYDSVVVKSRERPKKSKIPENELSN 558
                K + P   P  N +    ++ + +   NN +S +         +    N  SN
Sbjct: 249 -----KGESPSASPTHNTLGNGILNSNNNNNNNNNNSNINNINNNNNNNSNNNNNSSN 301

>sp|O01761|UNC89_CAEEL Muscle M-line assembly protein unc-89 (Uncoordinated protein 89)
          Length = 8081

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 39/157 (24%), Positives = 62/157 (39%), Gaps = 14/157 (8%)
 Frame = +1

Query: 10   KSRGRPRKLFVDDRSS--DTAPEIREKKFRG------RPRKTVLDDEKSSLSNGEPQAKK 165
            K    P K  V++  S  + +PE  E+K +        P K+  ++ KS     +   K 
Sbjct: 1706 KKEKSPEKSVVEEVKSPKEKSPEKAEEKPKSPTKKEKSPEKSAAEEVKSPTKKEKSPEKS 1765

Query: 166  SRGRPKKYTMQEDMNTPSSVKESNDNVKQXXXXXXXXXXXXXXXXXTGDSTEASEKQDNE 345
            +  +PK  T +E     S VK ++D VK                       +  EK   E
Sbjct: 1766 AEEKPKSPTKKES----SPVKMADDEVKSPTKKEKSPEKVEEKPASPTKKEKTPEKSAAE 1821

Query: 346  IV---VKKHKGRPSKSQKNEIDNKDK---KPRGRPKS 438
             +    KK K   S ++K   ++K+K   KP  +PKS
Sbjct: 1822 ELKSPTKKEKSPSSPTKKTGDESKEKSPEKPEEKPKS 1858

>sp|Q8BRH4|MLL3_MOUSE Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
           (Histone-lysine N-methyltransferase, H3 lysine-4
           specific MLL3)
          Length = 4903

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 19/55 (34%), Positives = 27/55 (49%)
 Frame = +1

Query: 355 KKHKGRPSKSQKNEIDNKDKKPRGRPKSNLVSEMHKDASETTNNYDSVVVKSRER 519
           K+ +GRP K   +      KKPR R KS +  E   D  ETT   + V  + +E+
Sbjct: 34  KRPRGRPRKDGASPFQRARKKPRSRGKSTVEDEDSMDGLETTETENIVETEIKEQ 88

>sp|P49711|CTCF_HUMAN Transcriptional repressor CTCF (CCCTC-binding factor) (CTCFL
           paralog) (11-zinc finger protein)
          Length = 727

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 23/80 (28%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
 Frame = +1

Query: 4   GRKSRGRPRKLFVDDRSSDTAPEIREKKFRGRPRKTVLDD-EKSSLSNGEPQAKKSRGRP 180
           GRK + R +K    D S +  P++ + +    P   +  + E   ++   P AKK RGRP
Sbjct: 597 GRKRKMRSKKEDSSD-SENAEPDLDDNEDEEEPAVEIEPEPEPQPVTPAPPPAKKRRGRP 655

Query: 181 KKYTMQEDMNTPSSVKESND 240
              T Q   N P+++ +  D
Sbjct: 656 PGRTNQPKQNQPTAIIQVED 675

>sp|P17096|HMGIY_HUMAN High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility
           group AT-hook 1) (High mobility group protein A1)
 sp|Q6URC2|HMGIY_CANFA High mobility group protein HMG-I/HMG-Y (HMG-I(Y)) (High mobility
           group AT-hook 1) (High mobility group protein A1)
          Length = 107

 Score = 35.0 bits (79), Expect = 0.19
 Identities = 29/92 (31%), Positives = 42/92 (45%), Gaps = 13/92 (14%)
 Frame = +1

Query: 313 STEASEKQDNEIVVKKHKGRPSK------------SQKNEID-NKDKKPRGRPKSNLVSE 453
           S   + KQ+ +   K+ +GRP K            SQK   +    K+PRGRPK +    
Sbjct: 9   SQPLASKQEKDGTEKRGRGRPRKQPPVSPGTALVGSQKEPSEVPTPKRPRGRPKGS---- 64

Query: 454 MHKDASETTNNYDSVVVKSRERPKKSKIPENE 549
            +K A++T     +   K R RPKK +  E E
Sbjct: 65  KNKGAAKTRKTTTTPGRKPRGRPKKLEKEEEE 96


 Score = 30.0 bits (66), Expect = 6.2
 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 9/75 (12%)
 Frame = +1

Query: 7   RKSRGRPRK---------LFVDDRSSDTAPEIREKKFRGRPRKTVLDDEKSSLSNGEPQA 159
           ++ RGRPRK         L    +     P    K+ RGRP+ +       +        
Sbjct: 23  KRGRGRPRKQPPVSPGTALVGSQKEPSEVPT--PKRPRGRPKGSKNKGAAKTRKTTTTPG 80

Query: 160 KKSRGRPKKYTMQED 204
           +K RGRPKK   +E+
Sbjct: 81  RKPRGRPKKLEKEEE 95

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.314    0.130    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,777,702
Number of Sequences: 369166
Number of extensions: 1250626
Number of successful extensions: 3756
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3426
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3711
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6122130210
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)

Cluster detail

DrC_00421

  1. Dr_sW_011_D20
  2. Dr_sW_009_L24