Planaria EST Database

DrC_00392

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00392
         (1435 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O95202|LETM1_HUMAN  Leucine zipper-EF-hand containing tra...   207   6e-53
sp|Q9Z2I0|LETM1_MOUSE  Leucine zipper-EF-hand containing tra...   204   4e-52
sp|Q5XIN6|LETM1_RAT  Leucine zipper-EF-hand containing trans...   204   7e-52
sp|P91927|A60DA_DROME  Calcium-binding mitochondrial protein...   173   1e-42
sp|O13920|YDWH_SCHPO  Hypothetical protein C23C11.17 in chro...    84   8e-16
sp|Q08179|MDM38_YEAST  Mitochondrial distribution and morpho...    74   1e-12
sp|P25386|USO1_YEAST  Intracellular protein transport protei...    49   5e-05
sp|P13535|MYH8_HUMAN  Myosin-8 (Myosin heavy chain, skeletal...    46   2e-04
sp|P49454|CENPF_HUMAN  CENP-F kinetochore protein (Centromer...    46   2e-04
sp|P35579|MYH9_HUMAN  Myosin-9 (Myosin heavy chain, nonmuscl...    45   4e-04

>sp|O95202|LETM1_HUMAN Leucine zipper-EF-hand containing transmembrane protein 1,
            mitochondrial precursor
          Length = 739

 Score =  207 bits (527), Expect = 6e-53
 Identities = 137/441 (31%), Positives = 225/441 (51%), Gaps = 56/441 (12%)
 Frame = +2

Query: 14   EVRETGQIARTDDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMK 193
            ++RETG+    ++I++FS+LF DE+TL +L   QL ALCKLLE+ SIG    L  +L M+
Sbjct: 292  KIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMR 351

Query: 194  VYILKVDDRMIIKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVP 373
            +  +K DD++I +EG+D++   ELQ  CR RGMRA G++EDRLR QL QW +L + +++P
Sbjct: 352  LRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTEDRLRGQLKQWLDLHLHQEIP 411

Query: 374  ISLLLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDVILR-SSTNDENVDSEPKFESITE 550
             SLL+LSR MYLP+ LSP  QL   + TLP  V+K+  ++ +    E VD++ K E+  +
Sbjct: 412  TSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEQVDNKAKLEATLQ 471

Query: 551  ELEHILTEVKEAERIEKETLIDR---AHQINIDAQDETTTKEKQLSGESISISDLNQIET 721
            E   I  E +E E ++K + + +     ++    Q   T  + ++    +    L     
Sbjct: 472  EEAAIQQEHREKE-LQKRSEVAKDFEPERVVAAPQRPGTEPQPEMPDTVLQSETLKDTAP 530

Query: 722  VIENLTSSETTDLE------GLDKLNEKAASLQEEDQLTESLK----------------- 832
            V+E L   E T  E         KL E+  SL +E +  E LK                 
Sbjct: 531  VLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKEL 590

Query: 833  ---SRESTHEETDAKRVLAVNIVSKAAQ--------------------------EKKISV 925
                 E   EE+ A + L   +     Q                          E  ISV
Sbjct: 591  SKTGEEKYVEESKASKRLTKRVQQMIGQIDGLISQLEMDQQAGKLAPANGMPTGENVISV 650

Query: 926  SDLMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELS 1105
            ++L+ A++Q++ I   E K   +   LDE+ DG + +  + KV +++  ++V +S  +++
Sbjct: 651  AELINAMKQVKHIP--ESKLTSLAAALDENKDGKVNIDDLVKVIELVDKEDVHISTSQVA 708

Query: 1106 RLIDTIGKEDDIGQETKPLEE 1168
             ++ T+ KE+ + ++ K  E+
Sbjct: 709  EIVATLEKEEKVEEKEKAKEK 729

>sp|Q9Z2I0|LETM1_MOUSE Leucine zipper-EF-hand containing transmembrane protein 1,
            mitochondrial precursor
          Length = 738

 Score =  204 bits (520), Expect = 4e-52
 Identities = 138/441 (31%), Positives = 223/441 (50%), Gaps = 56/441 (12%)
 Frame = +2

Query: 14   EVRETGQIARTDDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMK 193
            ++RETG+    ++I++FS+LF DE+TL +L   QL ALCKLLE+ SIG    L  +L M+
Sbjct: 291  KIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMR 350

Query: 194  VYILKVDDRMIIKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVP 373
            +  +K DD++I +EG+D++   ELQ  CR RGMRA G++EDRL+ QL QW +L +  ++P
Sbjct: 351  LRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLHHEIP 410

Query: 374  ISLLLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDVILR-SSTNDENVDSEPKFESITE 550
             SLL+LSR MYLP+ LSP  QL   + TLP  V+K+  ++ +    E VD++ K E+  +
Sbjct: 411  TSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKVAEVEGEKVDNKAKLEATLQ 470

Query: 551  ELEHILTEVKEAERIEKETLIDRAHQINIDAQDETTTKEKQLSGESISISD--LNQIETV 724
            E   I  E  E  +   E + D   ++           E Q   + + +    L     V
Sbjct: 471  EEAAIQQEHLEELKRASEAVKDIQPEVAEATLPGRPGPEPQPPVDDVILPSEVLTDTAPV 530

Query: 725  IENLTSSETTDLEGLDKLNEKAASLQEE----------------------DQLTESLKSR 838
            +E L   E T  E +D L++  + LQE+                      + L E  K  
Sbjct: 531  LEGLKGEEITK-EEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKEL 589

Query: 839  ESTHEETDAKRVLAVNIVSKAAQ-------------------------------EKKISV 925
              T EE   +   A   +SK  Q                               E  IS+
Sbjct: 590  SKTGEEKYIEESAASKRLSKRVQQMIGQIDGLITQLETTQQDGKLGPSQSTPTGESVISI 649

Query: 926  SDLMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELS 1105
            ++L+ A++Q++ I   E K   +   LD++ DG+I +  + KV D++  ++VQ+S  +++
Sbjct: 650  TELISAMKQIKHIP--EHKLISLTSALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVA 707

Query: 1106 RLIDTIGKEDDIGQETKPLEE 1168
             ++ T+ KE+ I ++ K  E+
Sbjct: 708  EIVATLEKEEKIEEKEKAKEK 728

>sp|Q5XIN6|LETM1_RAT Leucine zipper-EF-hand containing transmembrane protein 1,
            mitochondrial precursor
          Length = 739

 Score =  204 bits (518), Expect = 7e-52
 Identities = 145/445 (32%), Positives = 229/445 (51%), Gaps = 60/445 (13%)
 Frame = +2

Query: 14   EVRETGQIARTDDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMK 193
            ++RETG+    ++I++FS+LF DE+TL +L   QL ALCKLLE+ SIG    L  +L M+
Sbjct: 291  KIRETGERPSNEEIMRFSKLFEDELTLDNLTRPQLVALCKLLELQSIGTNNFLRFQLTMR 350

Query: 194  VYILKVDDRMIIKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVP 373
            +  +K DD++I +EG+D++   ELQ  CR RGMRA G++EDRL+ QL QW +L +  ++P
Sbjct: 351  LRSIKADDKLISEEGVDSLTVKELQAACRARGMRALGVTEDRLKGQLKQWLDLHLYHEIP 410

Query: 374  ISLLLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDVILRSS-TNDENVDSEPKFESITE 550
             SLL+LSR MYLP+ LSP  QL   + TLP  V+K+  ++++    E VD++ K E+  +
Sbjct: 411  TSLLILSRAMYLPDTLSPADQLKSTLQTLPEIVAKEAQVKAAEVEGEQVDNKAKLEATLQ 470

Query: 551  E-----LEHILTEVKEAERIEKETLIDRAHQINIDAQDETTTKEKQLSGESISISD-LNQ 712
            E      EH L E+K A    K+   + A +  +  +     + K +  + I  S+ L  
Sbjct: 471  EEAAIQQEH-LEELKRAAETAKDIQPEVA-EATVPGRPGAELQPKMV--DVIPPSEILKD 526

Query: 713  IETVIENLTSSETTDLE------GLDKLNEKAASLQEEDQLTESLKS------------- 835
               V+E L   E T  E         KL E+  SL +E +  E LK              
Sbjct: 527  TAPVLEGLKGEEITKEEIDILSDACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIK 586

Query: 836  ------------RESTHEETDAKRV----------------------LAVNIVSKAAQEK 913
                         EST  +  +KRV                      L     S    E 
Sbjct: 587  KELSKTGDEKYIEESTASKRLSKRVQQMIGQIDGLITQLETTQQNGKLDPAAASSPTGES 646

Query: 914  KISVSDLMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSA 1093
             ISV +L+ A++Q++ I   E K   +   LDE+ DG+I +  + KV D++  ++VQ+S 
Sbjct: 647  VISVDELISAMKQIKHIP--EHKLISLTSALDENKDGNINIDDLVKVIDLVNKEDVQIST 704

Query: 1094 KELSRLIDTIGKEDDIGQETKPLEE 1168
             +++ ++ T+ KE+ + ++ K  E+
Sbjct: 705  TQVAEIVATLEKEEKVEEKEKAKEK 729

>sp|P91927|A60DA_DROME Calcium-binding mitochondrial protein Anon-60Da
          Length = 1013

 Score =  173 bits (439), Expect = 1e-42
 Identities = 122/428 (28%), Positives = 219/428 (51%), Gaps = 56/428 (13%)
 Frame = +2

Query: 14   EVRETGQIARTDDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMK 193
            ++R   +    D+I+KF++ F+DEITL SL   QL ALC++LE+ +IG   +L  +L++K
Sbjct: 320  KIRNPTEPVSNDEIIKFAKRFDDEITLDSLSREQLAALCRVLELNTIGTTTLLRFQLRLK 379

Query: 194  VYILKVDDRMIIKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVP 373
            +  L  DDR+I +EG+D++   ELQQ C+ RGMRA+G++E+RLRFQL +W +LS+ +QVP
Sbjct: 380  LRSLATDDRVIAREGVDSLDLLELQQACKARGMRAYGLTEERLRFQLKEWIDLSLNEQVP 439

Query: 374  ISLLLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEE 553
             +LLLLSR M + ++     +L E I  LP  V          ++  VD++ K E I EE
Sbjct: 440  PTLLLLSRTMLISDDSITTDKLKETIRVLPDAVGAHTRHAIGESEGKVDNKTKIEIIKEE 499

Query: 554  LEHILTEVKEAERIEKETLIDRA------------------HQINIDAQDETTTKEKQLS 679
             E  + E +E ER  +ET+  R+                   Q  +D +++++  E   +
Sbjct: 500  -ERKIREEREEER--EETIAKRSAIKEEIPAPYVFAEKLSGSQDLLDHKEQSSVSE---T 553

Query: 680  GESISISDLNQIETVIENLTSSE--TTDLEGLDKLNEKAASLQEE-DQLTESLKSRESTH 850
             + IS +D+  +   ++ L+S +    + E + +L E+ A  +E+ ++L E  +  +   
Sbjct: 554  DKGISSTDVQLLSEALKTLSSDKQLVVEKETIKELKEELADYKEDVEELREVRQVVKEPV 613

Query: 851  EETDAKRVLAVNIVSKAAQ--------------------------------EKKISVSDL 934
             E+ A ++L   +    +Q                                ++ + + +L
Sbjct: 614  RESRAAKLLYNRVNKMISQLDNVLNDLEARQHQIKQAESSDYAASSPTVEPQQMVHIDEL 673

Query: 935  MKALRQLQSISGGEGKWQRILDV---LDEDHDGHIEVHHITKVFDILGHDEVQLSAKELS 1105
            +  +R+++  S  E +++ + D+   LD D DG I V+ ITK    +  +   +  K+L 
Sbjct: 674  VATIRRMKEAS-DEERFKVVGDLLVKLDADKDGVISVNEITKAVQSIDREATNIDKKQLE 732

Query: 1106 RLIDTIGK 1129
               + + K
Sbjct: 733  EFTELLSK 740

>sp|O13920|YDWH_SCHPO Hypothetical protein C23C11.17 in chromosome I
          Length = 485

 Score = 84.3 bits (207), Expect = 8e-16
 Identities = 59/229 (25%), Positives = 112/229 (48%), Gaps = 4/229 (1%)
 Frame = +2

Query: 14  EVRETGQIARTDDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMK 193
           +VR +GQ    +++++  + F D+ITL +L   QL A+C+ + + + G   +L   ++ +
Sbjct: 256 KVRTSGQSPSREELIEVCKYFKDDITLDNLSRAQLVAMCRYMNLNAFGTDPLLRYNIRHR 315

Query: 194 VYILKVDDRMIIKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVP 373
           +  ++ DDR I  EGI+++   EL   C  RG+R  G+S  +L+ +LS W ++ ++  +P
Sbjct: 316 MRQIRRDDRAIYIEGINSLSIPELFNACNSRGIRTQGLSPAKLKEELSVWLDMRIKHGIP 375

Query: 374 ISLLLLSRIMYLPENL----SPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFES 541
             +L+LS       N     S    L + + ++P ++  + +         VD   K  S
Sbjct: 376 SVILMLSNAFSYGYNEGTYDSRWDALQDTLASIPDELYHETV---------VDMPTKQVS 426

Query: 542 ITEELEHILTEVKEAERIEKETLIDRAHQINIDAQDETTTKEKQLSGES 688
             E LE IL E +E    E E + +         ++   T +  +S +S
Sbjct: 427 NKERLE-ILREQEELIEEEAEHVAEHPDLAKKQTEENKATSKPAVSAKS 474

>sp|Q08179|MDM38_YEAST Mitochondrial distribution and morphology protein 38, mitochondrial
            precursor
          Length = 573

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 70/294 (23%), Positives = 130/294 (44%), Gaps = 2/294 (0%)
 Frame = +2

Query: 47   DDIVKFSRLFNDEITLASLDHHQLRALCKLLEIASIGPKLVLISRLKMKVYILKVDDRMI 226
            D+I   +++F ++  L +L   QL A+ K + +   G   +L  +++ K+  +  DD+ I
Sbjct: 239  DEISAIAQMFKNDSVLDNLSRPQLAAMSKFMSLRPFGNDNMLRYQIRSKLKDIMNDDKTI 298

Query: 227  IKEGIDTIPTFELQQLCRERGMRAFGISEDRLRFQLSQWCNLSVEKQVPISLLLLSRIMY 406
              EG++++   EL Q C  RGM+A+G+S++ L   L  W  L + +++P  L++LS    
Sbjct: 299  DYEGVESLSQEELYQACVSRGMKAYGVSKEDLVDNLKVWLELRLRQKIPSVLMVLSSTFT 358

Query: 407  LPENLSPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEHILTEVKEA 586
                  P++  ++    L  K         S  D+ +D    ++ I + L  I   V   
Sbjct: 359  F--GGLPKENYSKAFSPLAEKKE-----TKSKYDDLLDL--YYDGILQVLSSIPDPVYNV 409

Query: 587  ERIEKETLIDRAHQINIDAQ--DETTTKEKQLSGESISISDLNQIETVIENLTSSETTDL 760
             +++       A +   + Q  ++    E++    +I   +    E+VI    S+ T  L
Sbjct: 410  AKLDVSESKSSAAETEAEKQVAEKKIKTEEKPEETAIPKEEATAKESVIATTASAVTPKL 469

Query: 761  EGLDKLNEKAASLQEEDQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKIS 922
                 +NEKA     E   TE +   +   E TD+         +  A+EKK S
Sbjct: 470  V---VVNEKA-----ETAKTEEISQEKENAEPTDSAE-------ATEAEEKKTS 508

>sp|P25386|USO1_YEAST Intracellular protein transport protein USO1 (Int-1)
          Length = 1790

 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 62/312 (19%), Positives = 136/312 (43%), Gaps = 30/312 (9%)
 Frame = +2

Query: 305  ISEDRLRFQLSQWCNLSVEKQVPISLLLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDV 484
            +S+++  FQ+ +    S+EK +      +S +    E +  +   ++  +     + K+ 
Sbjct: 1006 MSQEKENFQIERG---SIEKNIEQLKKTISDLEQTKEEIISKSDSSKDEYESQISLLKEK 1062

Query: 485  ILRSST-NDENVDSEPKFESITEELE-----------HILTEVKEAERIEKETLIDRAH- 625
            +  ++T NDENV+   +     EELE            + T+++ +E+  KE   +  H 
Sbjct: 1063 LETATTANDENVNKISELTKTREELEAELAAYKNLKNELETKLETSEKALKEVKENEEHL 1122

Query: 626  -QINIDAQDETTTKEKQLSGESISISDLN--------QIETVIENLTSSETTDLEGLDKL 778
             +  I  + E T  ++QL+    ++  L         Q++   E + + E    E + +L
Sbjct: 1123 KEEKIQLEKEATETKQQLNSLRANLESLEKEHEDLAAQLKKYEEQIANKERQYNEEISQL 1182

Query: 779  NEKAASLQEE--------DQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDL 934
            N++  S Q+E        D+L   +K+ +ST EE    +   ++ ++   Q K++   + 
Sbjct: 1183 NDEITSTQQENESIKKKNDELEGEVKAMKSTSEEQSNLKKSEIDALN--LQIKELKKKNE 1240

Query: 935  MKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRLI 1114
                  L+SI   E +  +I ++ DE +    EV  +         D+++ S  + S+ +
Sbjct: 1241 TNEASLLESIKSVESETVKIKELQDECNFKEKEVSEL--------EDKLKASEDKNSKYL 1292

Query: 1115 DTIGKEDDIGQE 1150
            +   + + I +E
Sbjct: 1293 ELQKESEKIKEE 1304


 Score = 42.7 bits (99), Expect = 0.003
 Identities = 42/183 (22%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
 Frame = +2

Query: 437  LNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEHILTEVKEAERIEKETLID 616
            LNE   T+  + S+ +   ++  DE +  + + E   +E+++  +E+++      E L +
Sbjct: 1372 LNEGSSTITQEYSEKI---NTLEDELIRLQNENELKAKEIDNTRSELEKVSLSNDELLEE 1428

Query: 617  RAHQINIDAQDE--------TTTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD 772
            + + I    QDE        T   EK LS E  +  DL  ++  +     S+    EGL 
Sbjct: 1429 KQNTIK-SLQDEILSYKDKITRNDEKLLSIERDNKRDLESLKEQLRAAQESKAKVEEGLK 1487

Query: 773  KLNEKAASLQEE-DQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALR 949
            KL E+++  + E ++  E +K  EST E  + +   ++  + K+ ++ + S     + ++
Sbjct: 1488 KLEEESSKEKAELEKSKEMMKKLESTIESNETELKSSMETIRKSDEKLEQSKKSAEEDIK 1547

Query: 950  QLQ 958
             LQ
Sbjct: 1548 NLQ 1550


 Score = 37.4 bits (85), Expect = 0.11
 Identities = 43/213 (20%), Positives = 96/213 (45%), Gaps = 25/213 (11%)
 Frame = +2

Query: 383  LLLSRIMYLPENLSPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEH 562
            +L + +  + ++L    QL +V+ T   +    ++   ST  +  DS    +++ + LE 
Sbjct: 794  ILETELKNVRDSLDEMTQLRDVLETKDKENQTALLEYKSTIHKQEDS---IKTLEKGLET 850

Query: 563  ILTEVKEAE------------------RIEK--ETLIDRAHQINIDAQDETTTKEKQLSG 682
            IL++ K+AE                   +E+  + L     + N++ Q ET + ++ ++ 
Sbjct: 851  ILSQKKKAEDGINKMGKDLFALSREMQAVEENCKNLQKEKDKSNVNHQKETKSLKEDIAA 910

Query: 683  ESISISDLNQIETVIENLTSSETTDLEGLDK-LNEKAASLQEED----QLTESLKSREST 847
            +   I  +N+    ++   ++ + + E + K L E  +  Q  D    +LTE LKS  + 
Sbjct: 911  KITEIKAINENLEEMKIQCNNLSKEKEHISKELVEYKSRFQSHDNLVAKLTEKLKSLANN 970

Query: 848  HEETDAKRVLAVNIVSKAAQEKKISVSDLMKAL 946
            +++  A+    +  V ++  E  I +S+L   +
Sbjct: 971  YKDMQAENESLIKAVEESKNESSIQLSNLQNKI 1003

>sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
            (MyHC-perinatal)
          Length = 1937

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 63/272 (23%), Positives = 123/272 (45%), Gaps = 14/272 (5%)
 Frame = +2

Query: 407  LPENLSPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEHILTEVKEA 586
            L ++ +  ++L E + TL  + +   +   S  D   D+E + E + +    +  ++KE 
Sbjct: 866  LAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLEAKIKEV 925

Query: 587  -ERIEKETLIDRAHQINI-DAQDETTTKEKQLSGESISISDLNQIETVIENLTSSETTDL 760
             ER E+E  I+          +DE +  +K +    ++++ + + +   EN   + T ++
Sbjct: 926  TERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEM 985

Query: 761  EGLD----KLNEKAASLQEEDQLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISV 925
             GLD    KL+++  +LQE  Q T + L++ E             VNI++KA  + +  V
Sbjct: 986  AGLDETIAKLSKEKKALQETHQQTLDDLQAEED-----------KVNILTKAKTKLEQQV 1034

Query: 926  SDLMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK--- 1096
             DL  +L Q       E K +  L+      +G +++   + +   + +D+ QL  K   
Sbjct: 1035 DDLEGSLEQ-------EKKLRMDLERAKRKLEGDLKLAQESTM--DMENDKQQLDEKLEK 1085

Query: 1097 ---ELSRLIDTIGKEDDIG-QETKPLEEFQTK 1180
               E+S LI  I  E  +  Q  K ++E Q +
Sbjct: 1086 KEFEISNLISKIEDEQAVEIQLQKKIKELQAR 1117

>sp|P49454|CENPF_HUMAN CENP-F kinetochore protein (Centromere protein F) (Mitosin) (AH
            antigen)
          Length = 3210

 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 62/249 (24%), Positives = 103/249 (41%), Gaps = 3/249 (1%)
 Frame = +2

Query: 401  MYLPENLSPEQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEHILTEVK 580
            + L E  S + QL E+         ++  L+ S +  + D   K   + EE+      + 
Sbjct: 2748 LLLEEIKSSKDQLKELTL-------ENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLH 2800

Query: 581  EAERIEKETLIDRAHQINIDAQ---DETTTKEKQLSGESISISDLNQIETVIENLTSSET 751
            EAE+  +  L+D   Q  ++ Q   ++ T+KE+ LS + + I  L   +  + N   + T
Sbjct: 2801 EAEKKHQALLLDTNKQYEVEIQTYREKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATT 2860

Query: 752  TDLEGLDKLNEKAASLQEEDQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSD 931
              LE L K   K  +L+  +QL       +  +E    K  L +    +  +EK+I    
Sbjct: 2861 QILEELKK--TKMDNLKYVNQL-------KKENERAQGKMKLLIKSCKQLEEEKEI---- 2907

Query: 932  LMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRL 1111
            L K L QLQ+      + Q+   V+D            TKV      DE+    KEL   
Sbjct: 2908 LQKELSQLQAAQ----EKQKTGTVMD------------TKV------DELTTEIKELKET 2945

Query: 1112 IDTIGKEDD 1138
            ++   KE D
Sbjct: 2946 LEEKTKEAD 2954


 Score = 32.0 bits (71), Expect = 4.6
 Identities = 53/236 (22%), Positives = 95/236 (40%), Gaps = 31/236 (13%)
 Frame = +2

Query: 344  CNLSVEKQVPISLLLLSRIMYLPENLSPEQQLN-------EVIFTLPPKVSKDVI----L 490
            C L  ++    S +L +R+  L  +L  ++Q+N       E +  +  ++ ++++    +
Sbjct: 814  CRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQM 873

Query: 491  RSSTNDENVDSEPKFESITEELEHILTEVKEA-ERIEKE--TLIDRAHQINIDAQD---- 649
              S   E      K +  T   ++++ E   A E  EKE   L D+      + Q+    
Sbjct: 874  HQSFVAETSQRISKLQEDTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQELKKS 933

Query: 650  ----ETTTKEKQLSGESI--------SISDLNQIETVIENLTSSETTDLEGLDKLN-EKA 790
                E + KE QL  E++        SI  LN+ E  IE LT    T  E    LN EK 
Sbjct: 934  NHLLEDSLKELQLLSETLSLEKKEMSSIISLNKRE--IEELTQENGTLKEINASLNQEKM 991

Query: 791  ASLQEEDQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQ 958
              +Q+ +     +  RE +  E   +      I+ +  +E   +  DL +  +  Q
Sbjct: 992  NLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQ 1047

>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
            chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
            heavy chain, type A) (Nonmuscle myosin heavy chain-A)
            (NMMHC-A)
          Length = 1960

 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 43/178 (24%), Positives = 79/178 (44%), Gaps = 4/178 (2%)
 Frame = +2

Query: 518  DSEPKFESITEELEHILTEVKEAERIEKETLIDRAHQINIDAQDETTTKEKQLSGESISI 697
            DSE K + +  +L+ +  +  E ER+  E L D+  ++ ++  + T    +  S  S   
Sbjct: 1242 DSEHKRKKVEAQLQELQVKFNEGERVRTE-LADKVTKLQVELDNVTGLLSQSDSKSSKLT 1300

Query: 698  SDLNQIETVIENLTSSETTDLEGLDKLNEKAASLQEEDQLTESLKSRESTHEETDAKRVL 877
             D + +E+ +++  + E    E   KL+      Q ED   E    RE   EE +AK  L
Sbjct: 1301 KDFSALESQLQD--TQELLQEENRQKLSLSTKLKQVED---EKNSFREQLEEEEEAKHNL 1355

Query: 878  AVNIVSKAAQEKKISVSDLMKALRQ----LQSISGGEGKWQRILDVLDEDHDGHIEVH 1039
               I +  AQ     V+D+ K +      L++    + K Q+ L+ L + H+  +  +
Sbjct: 1356 EKQIATLHAQ-----VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAY 1408


 Score = 35.0 bits (79), Expect = 0.54
 Identities = 44/220 (20%), Positives = 94/220 (42%), Gaps = 12/220 (5%)
 Frame = +2

Query: 338  QWCNLSVEKQVPISLLLLSRIMYLPENLSPEQQLNEVIFTLPPK-------VSKDVILRS 496
            Q C L+ EK+     LL  RI     NL+ E++ ++ +  L  K       + + +    
Sbjct: 986  QNCKLAKEKK-----LLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREE 1040

Query: 497  STNDENVDSEPKFESITEELEHILTEVKEAERIEKETLIDRAHQINIDAQDETTTKEKQL 676
                E   +  K E  + +L   + E++      K  L  +  ++    Q      E++ 
Sbjct: 1041 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEEL----QAALARVEEEA 1096

Query: 677  SGESISISDLNQIETVIENLTSSETTDLEGLDKLNEKAASLQEE-----DQLTESLKSRE 841
            + +++++  + ++E+ I  L     ++    +K  ++   L EE      +L ++L S  
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDST- 1155

Query: 842  STHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQS 961
            +  +E  +KR   VNI+ K  +E+  +    ++ +RQ  S
Sbjct: 1156 AAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHS 1195


 Score = 32.7 bits (73), Expect = 2.7
 Identities = 55/255 (21%), Positives = 112/255 (43%), Gaps = 4/255 (1%)
 Frame = +2

Query: 428  EQQLNEVIFTLPPKVSKDVILRSSTNDENVDSEPKFESITEELEHILTE-VKEAERIEKE 604
            +Q+L++++  L      D   +S+ N E    + KF+ +  E + I  +  +E +R E E
Sbjct: 1419 QQELDDLLVDL------DHQRQSACNLEK--KQKKFDQLLAEEKTISAKYAEERDRAEAE 1470

Query: 605  TLIDRAHQINIDAQDETTTKEKQLSGESISISDLN-QIETVIENLTSSETTDLEGLDKLN 781
                    +++    E   ++K        +  LN Q  T +E+L SS+    + + +L 
Sbjct: 1471 AREKETKALSLARALEEAMEQKA------ELERLNKQFRTEMEDLMSSKDDVGKSVHELE 1524

Query: 782  EKAASLQEE-DQLTESLKSRESTHEET-DAKRVLAVNIVSKAAQEKKISVSDLMKALRQL 955
            +   +L+++ +++   L+  E   + T DAK  L VN+ +  AQ ++    DL     Q 
Sbjct: 1525 KSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER----DLQGRDEQS 1580

Query: 956  QSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRLIDTIGKED 1135
            +     E K Q +  V   + +  +E     +   +    ++++  K+L   ID+  K  
Sbjct: 1581 E-----EKKKQLVRQV--REMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNR 1633

Query: 1136 DIGQETKPLEEFQTK 1180
            D  +  K L + Q +
Sbjct: 1634 D--EAIKQLRKLQAQ 1646

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 154,593,380
Number of Sequences: 369166
Number of extensions: 3179218
Number of successful extensions: 10828
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9928
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10776
length of database: 68,354,980
effective HSP length: 114
effective length of database: 47,295,190
effective search space used: 17168153970
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00392

  1. Dr_sW_010_J06
  2. Dr_sW_023_O13
  3. Dr_sW_004_N16