Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_023_O13
(694 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5XIN6|LETM1_RAT Leucine zipper-EF-hand containing trans... 59 1e-08
sp|Q9Z2I0|LETM1_MOUSE Leucine zipper-EF-hand containing tra... 56 8e-08
sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal... 38 0.029
sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle iso... 38 0.029
sp|Q5SX39|MYH4_MOUSE Myosin-4 (Myosin heavy chain, skeletal... 37 0.050
sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal... 36 0.084
sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle 36 0.084
sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, a... 36 0.084
sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal... 36 0.11
sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9 (Protein ki... 35 0.14
>sp|Q5XIN6|LETM1_RAT Leucine zipper-EF-hand containing transmembrane protein 1,
mitochondrial precursor
Length = 739
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/183 (23%), Positives = 89/183 (48%), Gaps = 6/183 (3%)
Frame = +1
Query: 25 DAQDEITTKEKQLSGESISISDLNQ-IETVIENLTS-----SETTDLEGLDKLNEKAASL 186
DA ++ ++K L+ E + L + ++ E+L S+T D + +++
Sbjct: 549 DACSKLKEQKKSLTKEKEELELLKEDVQDYSEDLQEIKKELSKTGDEKYIEESTASKRLS 608
Query: 187 QEEDQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEG 366
+ Q+ + + E T L S E ISV +L+ A++Q++ I E
Sbjct: 609 KRVQQMIGQIDGLITQLETTQQNGKLDPAAASSPTGESVISVDELISAMKQIKHIP--EH 666
Query: 367 KWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRLIDTIGKEDDIGQEIKP 546
K + LDE+ DG+I + + KV D++ ++VQ+S +++ ++ T+ KE+ + ++ K
Sbjct: 667 KLISLTSALDENKDGNINIDDLVKVIDLVNKEDVQISTTQVAEIVATLEKEEKVEEKEKA 726
Query: 547 LEE 555
E+
Sbjct: 727 KEK 729
>sp|Q9Z2I0|LETM1_MOUSE Leucine zipper-EF-hand containing transmembrane protein 1,
mitochondrial precursor
Length = 738
Score = 56.2 bits (134), Expect = 8e-08
Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 34/199 (17%)
Frame = +1
Query: 61 LSGESISISDLNQIETVIENLTSSE---TTDLEGLDKLNEKAASLQEEDQLTESLKSRES 231
L GE I+ +++ + L + T + E L+ L E E+ L E K
Sbjct: 534 LKGEEITKEEIDILSDACSKLQEQKKSLTKEKEELELLKEDVQDYSED--LQEIKKELSK 591
Query: 232 THEETDAKRVLAVNIVSKAAQ-------------------------------EKKISVSD 318
T EE + A +SK Q E IS+++
Sbjct: 592 TGEEKYIEESAASKRLSKRVQQMIGQIDGLITQLETTQQDGKLGPSQSTPTGESVISITE 651
Query: 319 LMKALRQLQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRL 498
L+ A++Q++ I E K + LD++ DG+I + + KV D++ ++VQ+S +++ +
Sbjct: 652 LISAMKQIKHIP--EHKLISLTSALDDNKDGNINIDDLVKVIDLVNKEDVQISTTQVAEI 709
Query: 499 IDTIGKEDDIGQEIKPLEE 555
+ T+ KE+ I ++ K E+
Sbjct: 710 VATLEKEEKIEEKEKAKEK 728
>sp|P13535|MYH8_HUMAN Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 37.7 bits (86), Expect = 0.029
Identities = 48/193 (24%), Positives = 90/193 (46%), Gaps = 14/193 (7%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD----KLNEKAASLQEED 198
+DE + +K + ++++ + + + EN + T ++ GLD KL+++ +LQE
Sbjct: 947 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETH 1006
Query: 199 QLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q T + L++ E VNI++KA + + V DL +L Q E K +
Sbjct: 1007 QQTLDDLQAEED-----------KVNILTKAKTKLEQQVDDLEGSLEQ-------EKKLR 1048
Query: 376 RILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK------ELSRLIDTIGKEDDIGQE 537
L+ +G +++ + + + +D+ QL K E+S LI I ED+ E
Sbjct: 1049 MDLERAKRKLEGDLKLAQESTM--DMENDKQQLDEKLEKKEFEISNLISKI--EDEQAVE 1104
Query: 538 I---KPLEEFQTK 567
I K ++E Q +
Sbjct: 1105 IQLQKKIKELQAR 1117
>sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle isoform
Length = 1102
Score = 37.7 bits (86), Expect = 0.029
Identities = 48/191 (25%), Positives = 87/191 (45%), Gaps = 12/191 (6%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQ----IETVIENLTSSETTDLEGLDKLNEKAASLQE-E 195
+DE + +K + I+++ + + E ++NLT T E + KL ++ SLQE
Sbjct: 110 EDECSELKKDIDDLEITLAKVEKEKHATENKVKNLTEEMATLDENISKLTKEKKSLQEAH 169
Query: 196 DQLTESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q+ + L++ E VN +SKA + + V DL +L Q E K +
Sbjct: 170 QQVLDDLQAEED-----------KVNTLSKAKVKLEQQVDDLEGSLEQ-------EKKVR 211
Query: 376 RILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK------ELSRLIDTIGKEDDIGQE 537
L+ +G +++ V D L +D++Q+ K E+S+L I E I +
Sbjct: 212 MDLERAKRKLEGDLKLTQ-ESVMD-LENDKLQMEEKLKKKEFEMSQLNSKIEDEQAIVMQ 269
Query: 538 I-KPLEEFQTK 567
+ K ++E Q +
Sbjct: 270 LQKKIKELQAR 280
>sp|Q5SX39|MYH4_MOUSE Myosin-4 (Myosin heavy chain, skeletal muscle, fetal)
Length = 1939
Score = 37.0 bits (84), Expect = 0.050
Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 12/191 (6%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD----KLNEKAASLQEED 198
+DE + +K + ++++ + + + EN + T ++ GLD KL ++ +LQE
Sbjct: 948 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAH 1007
Query: 199 QLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q T + L++ E VN ++KA + + V DL +L Q E K +
Sbjct: 1008 QQTLDDLQAEED-----------KVNTLTKAKTKLEQQVDDLEGSLEQ-------EKKLR 1049
Query: 376 RILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK------ELSRLIDTIGKEDDIGQE 537
L+ +G +++ DI +D+ QL K E+S L I E +G +
Sbjct: 1050 MDLERAKRKLEGDLKLAQ-ESTMDI-ENDKQQLDEKLKKKEFEMSNLQSKIEDEQALGMQ 1107
Query: 538 I-KPLEEFQTK 567
+ K ++E Q +
Sbjct: 1108 LQKKIKELQAR 1118
>sp|Q5SX40|MYH1_MOUSE Myosin-1 (Myosin heavy chain, skeletal muscle, adult 1)
Length = 1942
Score = 36.2 bits (82), Expect = 0.084
Identities = 42/186 (22%), Positives = 87/186 (46%), Gaps = 7/186 (3%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD----KLNEKAASLQEED 198
+DE + +K + ++++ + + + EN + T ++ GLD KL ++ +LQE
Sbjct: 951 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAH 1010
Query: 199 QLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q T + L++ E VN ++KA + + V DL +L Q + I + +
Sbjct: 1011 QQTLDDLQAEED-----------KVNTLTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK 1059
Query: 376 RILD-VLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRLIDTIGKEDDIGQEI-KPL 549
R L+ L + ++V + + D ++++ E+S L I E +G ++ K +
Sbjct: 1060 RKLEGDLKLAQESTMDVENDKQQLD----EKLKKKEFEMSNLQSKIEDEQALGMQLQKKI 1115
Query: 550 EEFQTK 567
+E Q +
Sbjct: 1116 KELQAR 1121
>sp|Q90339|MYSS_CYPCA Myosin heavy chain, fast skeletal muscle
Length = 1935
Score = 36.2 bits (82), Expect = 0.084
Identities = 44/191 (23%), Positives = 90/191 (47%), Gaps = 12/191 (6%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQ----IETVIENLTSSETTDLEGLDKLNEKAASLQEED 198
+DE + +K + ++++ + + E ++NLT + E + KL ++ +LQE
Sbjct: 945 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMASQDESIAKLTKEKKALQEAH 1004
Query: 199 QLT-ESLKSRE-STHEETDAKRVL---AVNIVSKAAQEKKISVSDLMKALRQLQSISGGE 363
Q T + L++ E + T AK L ++ QEKK+ + DL +A R+L+ G+
Sbjct: 1005 QQTLDDLQAEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKLRM-DLERAKRKLE----GD 1059
Query: 364 GK--WQRILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAKELSRLIDTIGKEDDIGQE 537
K + I+D+ +E ++++ E+S+L+ I E +G +
Sbjct: 1060 LKLAQESIMDLENEKQQ---------------SDEKIKKKDFEISQLLSKIEDEQSLGAQ 1104
Query: 538 I-KPLEEFQTK 567
+ K ++E Q +
Sbjct: 1105 LQKKIKELQAR 1115
>sp|P13538|MYSS_CHICK Myosin heavy chain, skeletal muscle, adult
Length = 1939
Score = 36.2 bits (82), Expect = 0.084
Identities = 45/191 (23%), Positives = 87/191 (45%), Gaps = 12/191 (6%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD----KLNEKAASLQEED 198
+DE + +K + ++++ + + + EN + T ++ LD KL ++ +LQE
Sbjct: 947 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAVLDETIAKLTKEKKALQEAH 1006
Query: 199 QLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q T + L+ E VN ++KA + + V DL +L Q E K +
Sbjct: 1007 QQTLDDLQVEED-----------KVNTLTKAKTKLEQQVDDLEGSLEQ-------EKKLR 1048
Query: 376 RILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK------ELSRLIDTIGKEDDIGQE 537
L+ +G +++ H + D L +D+ QL K E+S++ I E +G +
Sbjct: 1049 MDLERAKRKLEGDLKLAH-DSIMD-LENDKQQLDEKLKKKDFEISQIQSKIEDEQALGMQ 1106
Query: 538 I-KPLEEFQTK 567
+ K ++E Q +
Sbjct: 1107 LQKKIKELQAR 1117
>sp|P13542|MYH8_MOUSE Myosin-8 (Myosin heavy chain, skeletal muscle, perinatal)
(MyHC-perinatal)
Length = 1937
Score = 35.8 bits (81), Expect = 0.11
Identities = 49/193 (25%), Positives = 87/193 (45%), Gaps = 14/193 (7%)
Frame = +1
Query: 31 QDEITTKEKQLSGESISISDLNQIETVIENLTSSETTDLEGLD----KLNEKAASLQEED 198
+DE + +K + ++++ + + + EN + T ++ GLD KL ++ +LQE
Sbjct: 947 EDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAGLDENIAKLTKEKKALQEAH 1006
Query: 199 QLT-ESLKSRESTHEETDAKRVLAVNIVSKAAQEKKISVSDLMKALRQLQSISGGEGKWQ 375
Q T + L++ E VN ++KA + + V DL +L Q E K +
Sbjct: 1007 QQTLDDLQAEED-----------KVNTLTKAKTKLEQQVDDLEGSLEQ-------EKKLR 1048
Query: 376 RILDVLDEDHDGHIEVHHITKVFDILGHDEVQLSAK------ELSRLIDTIGKEDDIGQE 537
L+ +G +++ DI +D+ QL K E+S LI I ED+ E
Sbjct: 1049 MDLERAKRKLEGDLKLAQ-ESTMDI-ENDKQQLDEKLKKKEFEISNLISKI--EDEQAVE 1104
Query: 538 I---KPLEEFQTK 567
I K ++E Q +
Sbjct: 1105 IQLQKKIKELQAR 1117
>sp|Q99996|AKAP9_HUMAN A-kinase anchor protein 9 (Protein kinase A anchoring protein 9)
(PRKA9) (A-kinase anchor protein 450 kDa) (AKAP 450)
(A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350)
(AKAP 120-like protein) (Hyperion protein) (Yotiao
protein) (Centrosome- and Golgi-localized PKN-associated
protein) (CG-NAP)
Length = 3911
Score = 35.4 bits (80), Expect = 0.14
Identities = 52/216 (24%), Positives = 94/216 (43%), Gaps = 32/216 (14%)
Frame = +1
Query: 10 HQINIDAQDEITTKEKQLSGESISISD----LNQIETVIENLTSS-------ETTDLEGL 156
+++NI QD + KEK + + + Q+E ++E L+ S T E
Sbjct: 508 NELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFSREQIQRARQTIAEQE 567
Query: 157 DKLNEKAASLQEEDQLTESLKSRESTHEETDAK---RVLAVNIVSKAAQEKKISVSDLMK 327
KLNE SL + L + S + +E + K V I + +++K +V D M
Sbjct: 568 SKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKLEMLEKEKNAVLDRMA 627
Query: 328 ALRQ-------LQSISGGEGKWQRILDVLDEDHDGHIEVHHITKVFDILG-HDEVQLSA- 480
++ Q + E + ++ + L+ +H +IE K+ D LG H + Q+
Sbjct: 628 ESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIE-----KLKDNLGIHYKQQIDGL 682
Query: 481 -KELSRLIDT--------IGKEDDIGQEIKPLEEFQ 561
E+S+ I+T I K++ + EI L++ Q
Sbjct: 683 QNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQ 718
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,863,402
Number of Sequences: 369166
Number of extensions: 1565193
Number of successful extensions: 5648
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5359
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5639
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5976365205
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)