Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00387 (1071 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O75954|TSN9_HUMAN Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) 44 6e-04 sp|Q8BJU2|TSN9_MOUSE Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) 43 0.002 sp|Q61451|CD53_MOUSE Leukocyte surface antigen CD53 (Cell s... 35 0.37 sp|P24485|CD53_RAT Leukocyte surface antigen CD53 (Cell sur... 33 1.1 sp|Q9DCK3|TSN4_MOUSE Tetraspanin-4 (Tspan-4) (Transmembrane... 33 1.4 sp|O14817|TSN4_HUMAN Tetraspanin-4 (Tspan-4) (Transmembrane... 32 4.0 sp|Q9D6K9|LASS5_MOUSE LAG1 longevity assurance homolog 5 (T... 31 5.3 sp|O95859|TSN12_HUMAN Tetraspanin-12 (Tspan-12) (Transmembr... 30 9.0 sp|Q8N5B7|LASS5_HUMAN LAG1 longevity assurance homolog 5 30 9.0 sp|P16893|TRAP_PLAFA Thrombospondin-related anonymous prote... 30 9.0
>sp|O75954|TSN9_HUMAN Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) Length = 239 Score = 44.3 bits (103), Expect = 6e-04 Identities = 28/126 (22%), Positives = 54/126 (42%), Gaps = 9/126 (7%) Frame = +3 Query: 93 ILDHGLMLEITSGSIY--------LTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXX 248 +L G+ L ++ G+ L+ L+I +G I+ T G G++KE++ + Sbjct: 27 LLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSF 86 Query: 249 XXXXXXXXXXXXXXXXXXXXXPSSLNDSTKAEMKRTLINQYARTRL-ITDAWNLTQNRLR 425 +N++ K ++K L+ + + + +AWN+ Q +R Sbjct: 87 FIVLLVILLAELILLILFFVYMDKVNENAKKDLKEGLLLYHTENNVGLKNAWNIIQAEMR 146 Query: 426 CCGVED 443 CCGV D Sbjct: 147 CCGVTD 152
>sp|Q8BJU2|TSN9_MOUSE Tetraspanin-9 (Tspan-9) (Tetraspan NET-5) Length = 239 Score = 42.7 bits (99), Expect = 0.002 Identities = 28/126 (22%), Positives = 53/126 (42%), Gaps = 9/126 (7%) Frame = +3 Query: 93 ILDHGLMLEITSGSIY--------LTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXX 248 +L G+ L ++ G+ L+ L+I +G I+ T G G++KE++ + Sbjct: 27 LLGVGIWLSVSQGNFATFSPSFPSLSAANLVIAIGTIVMVTGFLGCLGAIKENKCLLLSF 86 Query: 249 XXXXXXXXXXXXXXXXXXXXXPSSLNDSTKAEMKRTLINQYARTRL-ITDAWNLTQNRLR 425 +N++ K ++K L+ + + +AWN+ Q +R Sbjct: 87 FIVLLIILLAELILIILFFVYMDKVNENAKQDLKEGLLLYNTENNVGLKNAWNIIQAEMR 146 Query: 426 CCGVED 443 CCGV D Sbjct: 147 CCGVTD 152
>sp|Q61451|CD53_MOUSE Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) Length = 219 Score = 35.0 bits (79), Expect = 0.37 Identities = 25/100 (25%), Positives = 37/100 (37%) Frame = +3 Query: 138 YLTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXXXXXXXXXXXXXXXXXXXXXXXPS 317 +LT +L+ VG I+ G GS+KE++ + Sbjct: 49 FLTLGNILVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLIILLAEVTIAILLFVYEQ 108 Query: 318 SLNDSTKAEMKRTLINQYARTRLITDAWNLTQNRLRCCGV 437 LN + AE I Y AW+ Q +L+CCGV Sbjct: 109 KLN-TLVAEGLNDSIQHYHSDNSTMKAWDFIQTQLQCCGV 147
>sp|P24485|CD53_RAT Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Leukocyte antigen MRC OX-44) Length = 219 Score = 33.5 bits (75), Expect = 1.1 Identities = 24/100 (24%), Positives = 38/100 (38%) Frame = +3 Query: 138 YLTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXXXXXXXXXXXXXXXXXXXXXXXPS 317 +LT +L+ VG I+ G GS+KE++ + Sbjct: 49 FLTLGNVLVIVGSIIMVVAFLGCMGSIKENKCLLMSFFVLLLLILLAEVTLAILLFVYEK 108 Query: 318 SLNDSTKAEMKRTLINQYARTRLITDAWNLTQNRLRCCGV 437 +N + AE I Y AW+ Q++L+CCGV Sbjct: 109 KIN-TLVAEGLNDSIQHYHSDNSTRMAWDFIQSQLQCCGV 147
>sp|Q9DCK3|TSN4_MOUSE Tetraspanin-4 (Tspan-4) (Transmembrane 4 superfamily member 7) Length = 238 Score = 33.1 bits (74), Expect = 1.4 Identities = 35/170 (20%), Positives = 61/170 (35%), Gaps = 7/170 (4%) Frame = +3 Query: 135 IYLTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXXXXXXXXXXXXXXXXXXXXXXXP 314 + +TGT+++ +GF+ C G+LKE++ + Sbjct: 57 LIVTGTFVMA-IGFVGCI-------GALKENKCLLLTFFVLLLLVFLLEATIAVLFFAYS 108 Query: 315 SSLNDSTKAEMKRTLINQYARTRL-ITDAWNLTQNRLRCCGVEDGQWDIYINSYWDNITN 491 ++ + ++K+ L + + +T+AW++ Q RCCGV + + W + N Sbjct: 109 DKIDSYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFRCCGVSN-------YTDWFEVYN 161 Query: 492 IDLNNMNLKISRHNPFYQFVPISCCWLLVD------PQTGWPGTVYRNVK 623 VP SCC D P T W Y VK Sbjct: 162 ATR----------------VPDSCCLEFSDSCGLHEPGTWWKSPCYETVK 195
>sp|O14817|TSN4_HUMAN Tetraspanin-4 (Tspan-4) (Transmembrane 4 superfamily member 7) (Novel antigen 2) (NAG-2) Length = 238 Score = 31.6 bits (70), Expect = 4.0 Identities = 39/192 (20%), Positives = 64/192 (33%), Gaps = 15/192 (7%) Frame = +3 Query: 93 ILDHGLMLEITSGSIY--------LTGTYLLIFVGFILCFTVCFGTYGSLKEDRFMXXXX 248 +L G+ L T GS L+ LLI G + G G++KE++ + Sbjct: 27 VLGVGIWLAATQGSFATLSSSFPSLSAANLLIITGAFVMAIGFVGCLGAIKENKCLLLTF 86 Query: 249 XXXXXXXXXXXXXXXXXXXXXPSSLNDSTKAEMKRTLINQYARTRL-ITDAWNLTQNRLR 425 ++ + ++K+ L + + +T+AW++ Q R Sbjct: 87 FLLLLLVFLLEATIAILFFAYTDKIDRYAQQDLKKGLHLYGTQGNVGLTNAWSIIQTDFR 146 Query: 426 CCGVEDGQWDIYINSYWDNITNIDLNNMNLKISRHNPFYQFVPISCCWLLVD------PQ 587 CCGV + + W + N VP SCC + P Sbjct: 147 CCGVSN-------YTDWFEVYNATR----------------VPDSCCLEFSESCGLHAPG 183 Query: 588 TGWPGTVYRNVK 623 T W Y VK Sbjct: 184 TWWKAPCYETVK 195
>sp|Q9D6K9|LASS5_MOUSE LAG1 longevity assurance homolog 5 (Translocating chain-associating membrane protein homolog 4) (TRAM homolog 4) Length = 414 Score = 31.2 bits (69), Expect = 5.3 Identities = 17/67 (25%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Frame = +2 Query: 20 TSFCY----FKFYIITFCISTCYCWYK*YTRPWVNARNNKWLNIFNRNLSFDICRFYFVL 187 T FC F +Y+ FC + W + PW W N + LS ++ +Y Sbjct: 139 TKFCESMWRFTYYLCIFCYGIRFLW----SMPWFWDTRQCWYNYPYQPLSRELYYYYITQ 194 Query: 188 HRLFWNL 208 +W+L Sbjct: 195 LAFYWSL 201
>sp|O95859|TSN12_HUMAN Tetraspanin-12 (Tspan-12) (Transmembrane 4 superfamily member 12) (Tetraspan NET-2) Length = 305 Score = 30.4 bits (67), Expect = 9.0 Identities = 15/41 (36%), Positives = 20/41 (48%) Frame = +3 Query: 375 RTRLITDAWNLTQNRLRCCGVEDGQWDIYINSYWDNITNID 497 R R +T AWN Q +CCGV +Y W +T +D Sbjct: 142 RYRWLTHAWNFFQREFKCCGV------VYFTD-WLEMTEMD 175
>sp|Q8N5B7|LASS5_HUMAN LAG1 longevity assurance homolog 5 Length = 392 Score = 30.4 bits (67), Expect = 9.0 Identities = 18/67 (26%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Frame = +2 Query: 20 TSFCY----FKFYIITFCISTCYCWYK*YTRPWVNARNNKWLNIFNRNLSFDICRFYFVL 187 T FC F FY+ FC + W + PW W N + LS + +Y + Sbjct: 139 TKFCESMWRFTFYLCIFCYGIRFLW----SSPWFWDIRQCWHNYPFQPLSSGLYHYYIME 194 Query: 188 HRLFWNL 208 +W+L Sbjct: 195 LAFYWSL 201
>sp|P16893|TRAP_PLAFA Thrombospondin-related anonymous protein precursor Length = 559 Score = 30.4 bits (67), Expect = 9.0 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Frame = +3 Query: 312 PSSLNDSTKAEMKRTLINQYARTRLITDAWNLTQNR-LRCCGVEDGQWDIYINSYWDNIT 488 P S+ DS K K + I N+ NR L C DG+ ++Y +S W+N+ Sbjct: 165 PDSIQDSLKESRKLSDRGVKIAVFGIGQGINVAFNRFLVGCHPSDGKCNLYADSAWENVK 224 Query: 489 NI 494 N+ Sbjct: 225 NV 226
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 114,273,167 Number of Sequences: 369166 Number of extensions: 2307805 Number of successful extensions: 5745 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5534 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5742 length of database: 68,354,980 effective HSP length: 112 effective length of database: 47,664,660 effective search space used: 11630177040 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)