Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00379 (544 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransfera... 171 8e-43 sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransfera... 171 1e-42 sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferas... 171 1e-42 sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransfera... 171 1e-42 sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransfera... 167 2e-41 sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransfera... 165 8e-41 sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransfera... 162 6e-40 sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoylt... 140 2e-33 sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoylt... 119 5e-27 sp|P34809|NMT_CRYNV Glycylpeptide N-tetradecanoyltransferas... 117 1e-26
>sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide N-myristoyltransferase 2) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Type II N-myristoyltransferase) Length = 498 Score = 171 bits (434), Expect = 8e-43 Identities = 87/154 (56%), Positives = 111/154 (72%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D +L+N YL +F L A EE HWF+PR +I+ TFVVE P+G +TD S+Y+L Sbjct: 347 DIKSVRELINTYLKQFHL-APVMDEEEVAHWFLpreHIIDTFVVESPNGKLTDFLSFYTL 405 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PS+V+ +P H L AAYSFYN+ +E T + LM DALI AKS+GFDVFNAL++M+NK FL Sbjct: 406 PSTVMHHPAHKSLKAAYSFYNIHTE-TPLLDLMSDALILAKSKGFDVFNALDLMENKTFL 464 Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 ++LKFG GDG L YYLYNW+CP +S V LVLQ Sbjct: 465 EKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 498
>sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide N-myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) Length = 496 Score = 171 bits (433), Expect = 1e-42 Identities = 85/154 (55%), Positives = 110/154 (71%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D P +LL YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+L Sbjct: 345 DIPVVHQLLTRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462 Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 ++LKFG GDG L YYLYNW+CP M + V LVLQ Sbjct: 463 EKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferase (Peptide N-myristoyltransferase) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) (dNMT) Length = 472 Score = 171 bits (433), Expect = 1e-42 Identities = 84/153 (54%), Positives = 106/153 (69%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D +A KLL DYL +F+L F S EEF HWF P+ I+ FVV G ITD+ SYY L Sbjct: 321 DMDKAHKLLEDYLKRFQLSPVF-SKEEFRHWFTPKEGIIDCFVVADEKGNITDLTSYYCL 379 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PSSV+ +P H + AAYSFYNV S KT W+ LM DALI A++ DV+NAL++M+NK++ Sbjct: 380 PSSVMHHPVHKTVRAAYSFYNV-STKTPWLDLMNDALISARNVQMDVYNALDLMENKKYF 438 Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVL 459 LKFG GDG L YYLYNW+CP M ++AL+L Sbjct: 439 APLKFGAGDGNLQYYLYNWRCPSMQPEEIALIL 471
>sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 (Peptide N-myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) Length = 496 Score = 171 bits (432), Expect = 1e-42 Identities = 84/154 (54%), Positives = 110/154 (71%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D P +LL+ YL +F L EE EHWF P+ NI+ TFVVE +G +TD S+Y+L Sbjct: 345 DIPVVHQLLSRYLKQFHLTPVMNQ-EEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462 Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 ++LKFG GDG L YYLYNW+CP M + V LVLQ Sbjct: 463 EKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide N-myristoyltransferase 1) (Myristoyl-CoA:protein N-myristoyltransferase 1) (NMT 1) (Type I N-myristoyltransferase) Length = 497 Score = 167 bits (422), Expect = 2e-41 Identities = 85/155 (54%), Positives = 111/155 (71%), Gaps = 1/155 (0%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D P +LL+ YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+L Sbjct: 345 DIPVVHQLLSRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462 Query: 361 KELKFGPGDG-QLHYYLYNWQCPQMNSGDVALVLQ 462 ++LKFG GDG L YYLYNW+CP M + V LVLQ Sbjct: 463 EKLKFGIGDGNNLQYYLYNWKCPSMGAEKVGLVLQ 497
>sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransferase 2 (Peptide N-myristoyltransferase 2) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Type II N-myristoyltransferase) Length = 529 Score = 165 bits (417), Expect = 8e-41 Identities = 83/148 (56%), Positives = 106/148 (71%) Frame = +1 Query: 19 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 198 +L+N YL +F L E HWF+PR +I+ TFVVE P G +TD S+Y+LPS+V+ Sbjct: 384 ELINIYLKQFHLAPVMDDAE-VAHWFLpreHIIDTFVVENPSGKLTDFLSFYTLPSTVMH 442 Query: 199 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 378 +P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG Sbjct: 443 HPAHKSLKAAYSFYNIHTE-TPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 501 Query: 379 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 GDG L YYLYNW+CP +S V LVLQ Sbjct: 502 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 529
>sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide N-myristoyltransferase 2) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Type II N-myristoyltransferase) Length = 498 Score = 162 bits (409), Expect = 6e-40 Identities = 83/148 (56%), Positives = 105/148 (70%) Frame = +1 Query: 19 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 198 +L N YL +F L A EE HWF+P+ +I+ TFVVE G +TD S+Y+LPS+V+ Sbjct: 353 ELTNTYLKQFHL-APVMDEEEVAHWFLPQEHIIDTFVVENSSGKLTDFLSFYTLPSTVMH 411 Query: 199 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 378 +P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG Sbjct: 412 HPAHKSLKAAYSFYNIHTE-TPLLDLMSDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 470 Query: 379 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 GDG L YYLYNW+CP S V LVLQ Sbjct: 471 IGDGNLQYYLYNWRCPGTESEKVGLVLQ 498
>sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoyltransferase (Peptide N-myristoyltransferase) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) Length = 450 Score = 140 bits (354), Expect = 2e-33 Identities = 71/154 (46%), Positives = 95/154 (61%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180 D PQ FKLL L ++ L + S EE H +P+ +V ++V E +G ITD S+YSL Sbjct: 298 DVPQVFKLLTTSLKQYSLAPVYNSEEELAHALVPKKGVVYSYVAENQNGKITDFVSFYSL 357 Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360 PS+V+ + H + AAY +Y VA T L+ D+LI A E FDVFNAL++M N++ Sbjct: 358 PSTVMGHTTHKTIYAAYLYYYVAGSVTPK-QLINDSLILANREKFDVFNALDLMHNEKIF 416 Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462 +LKFG GDG L YYLYNW+C M + LVLQ Sbjct: 417 SDLKFGKGDGNLQYYLYNWKCADMKPSQIGLVLQ 450
>sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoyltransferase (Peptide N-myristoyltransferase) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) Length = 466 Score = 119 bits (298), Expect = 5e-27 Identities = 71/166 (42%), Positives = 101/166 (60%), Gaps = 19/166 (11%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVS-----TFVVEQPDGT-ITDM 162 D P LL+ Y+ +F+L A S EE HWF+ + S ++VVE P+ ITD Sbjct: 282 DVPAVQSLLSQYMERFEL-AHLFSEEEVRHWFLYTDKVSSGPVVWSYVVENPESKKITDF 340 Query: 163 CSYYSLPSSVIDNPHHSKLCAAYSFY--------NVASE-KTGWIP----LMRDALIQAK 303 S+YSLPS+VI NP + + AAY +Y +++SE + ++ ++ DALI AK Sbjct: 341 FSFYSLPSTVIGNPKYKDIQAAYLYYYASDSCPKDLSSESQLAFVERCKLIVNDALILAK 400 Query: 304 SEGFDVFNALNVMDNKEFLKELKFGPGDGQLHYYLYNWQCPQMNSG 441 FDVFNA+ V+DN FLK+LKFG GDG L+YY+YN+ CP++ G Sbjct: 401 KFHFDVFNAVTVLDNNLFLKDLKFGEGDGFLNYYIYNYNCPKIPGG 446
>sp|P34809|NMT_CRYNV Glycylpeptide N-tetradecanoyltransferase (Peptide N-myristoyltransferase) (Myristoyl-CoA:protein N-myristoyltransferase) (NMT) Length = 598 Score = 117 bits (294), Expect = 1e-26 Identities = 74/196 (37%), Positives = 97/196 (49%), Gaps = 49/196 (25%) Frame = +1 Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLN----------IVSTFVVEQPDG- 147 D PQ LL YL++F + F +E EHWF+ +V +VVE P Sbjct: 386 DVPQVGALLRRYLDRFDVAQAFKDDDEVEHWFLSGQGKEVGGRRVEQVVWAYVVEDPTTH 445 Query: 148 TITDMCSYYSLPSSVIDNPHHSKLCAAYSFY-------------------------NVAS 252 ITD+ S+Y+LPS+++ +P H+ L AAY FY +VA+ Sbjct: 446 RITDLISFYALPSTIMKHPKHNLLNAAYMFYYATDVIFPPPSSSAHSDADVNAGESSVAA 505 Query: 253 EKTGWIP-------------LMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFGPGDGQ 393 TG L D LI AK GFDVFNAL ++DN FL+E KFGPGDG Sbjct: 506 VGTGGEDAKTKKKLETRLNALTADLLIIAKQAGFDVFNALTLLDNNMFLQEQKFGPGDGY 565 Query: 394 LHYYLYNWQCPQMNSG 441 L+YYLYNW C ++ G Sbjct: 566 LNYYLYNWNCAPIDGG 581
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 60,918,889 Number of Sequences: 369166 Number of extensions: 1187631 Number of successful extensions: 2699 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2625 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2677 length of database: 68,354,980 effective HSP length: 104 effective length of database: 49,142,540 effective search space used: 3734833040 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)