Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_N23
(530 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransfera... 171 1e-42
sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferas... 168 9e-42
sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransfera... 167 1e-41
sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransfera... 167 1e-41
sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransfera... 165 7e-41
sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransfera... 163 2e-40
sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransfera... 162 6e-40
sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoylt... 134 1e-31
sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoylt... 116 4e-26
sp|Q9UVX3|NMT_ASPFU Glycylpeptide N-tetradecanoyltransferas... 115 5e-26
>sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 171 bits (433), Expect = 1e-42
Identities = 86/148 (58%), Positives = 110/148 (74%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+L+N YL +F L A EE HWF+PR +I+ TFVVE P+G +TD S+Y+LPS+V+
Sbjct: 353 ELINTYLKQFHL-APVMDEEEVAHWFLpreHIIDTFVVESPNGKLTDFLSFYTLPSTVMH 411
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYN+ +E T + LM DALI AKS+GFDVFNAL++M+NK FL++LKFG
Sbjct: 412 HPAHKSLKAAYSFYNIHTE-TPLLDLMSDALILAKSKGFDVFNALDLMENKTFLEKLKFG 470
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP +S V LVLQ
Sbjct: 471 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 498
>sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT) (dNMT)
Length = 472
Score = 168 bits (425), Expect = 9e-42
Identities = 82/147 (55%), Positives = 103/147 (70%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
KLL DYL +F+L F S EEF HWF P+ I+ FVV G ITD+ SYY LPSSV+
Sbjct: 327 KLLEDYLKRFQLSPVF-SKEEFRHWFTPKEGIIDCFVVADEKGNITDLTSYYCLPSSVMH 385
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H + AAYSFYNV S KT W+ LM DALI A++ DV+NAL++M+NK++ LKFG
Sbjct: 386 HPVHKTVRAAYSFYNV-STKTPWLDLMNDALISARNVQMDVYNALDLMENKKYFAPLKFG 444
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVL 445
GDG L YYLYNW+CP M ++AL+L
Sbjct: 445 AGDGNLQYYLYNWRCPSMQPEEIALIL 471
>sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 167 bits (424), Expect = 1e-41
Identities = 83/148 (56%), Positives = 108/148 (72%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+LL YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+LPS++++
Sbjct: 351 QLLTRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMN 409
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 410 HPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG 468
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP M + V LVLQ
Sbjct: 469 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 167 bits (423), Expect = 1e-41
Identities = 82/148 (55%), Positives = 108/148 (72%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+LL+ YL +F L EE EHWF P+ NI+ TFVVE +G +TD S+Y+LPS++++
Sbjct: 351 QLLSRYLKQFHLTPVMNQ-EEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMN 409
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 410 HPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG 468
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP M + V LVLQ
Sbjct: 469 IGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 529
Score = 165 bits (417), Expect = 7e-41
Identities = 83/148 (56%), Positives = 106/148 (71%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+L+N YL +F L E HWF+PR +I+ TFVVE P G +TD S+Y+LPS+V+
Sbjct: 384 ELINIYLKQFHLAPVMDDAE-VAHWFLpreHIIDTFVVENPSGKLTDFLSFYTLPSTVMH 442
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 443 HPAHKSLKAAYSFYNIHTE-TPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 501
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP +S V LVLQ
Sbjct: 502 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 529
>sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 497
Score = 163 bits (413), Expect = 2e-40
Identities = 83/149 (55%), Positives = 109/149 (73%), Gaps = 1/149 (0%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+LL+ YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+LPS++++
Sbjct: 351 QLLSRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMN 409
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 410 HPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG 468
Query: 365 PGDG-QLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP M + V LVLQ
Sbjct: 469 IGDGNNLQYYLYNWKCPSMGAEKVGLVLQ 497
>sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 162 bits (409), Expect = 6e-40
Identities = 83/148 (56%), Positives = 105/148 (70%)
Frame = +2
Query: 5 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 184
+L N YL +F L A EE HWF+P+ +I+ TFVVE G +TD S+Y+LPS+V+
Sbjct: 353 ELTNTYLKQFHL-APVMDEEEVAHWFLPQEHIIDTFVVENSSGKLTDFLSFYTLPSTVMH 411
Query: 185 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 364
+P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 412 HPAHKSLKAAYSFYNIHTE-TPLLDLMSDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 470
Query: 365 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
GDG L YYLYNW+CP S V LVLQ
Sbjct: 471 IGDGNLQYYLYNWRCPGTESEKVGLVLQ 498
>sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 450
Score = 134 bits (337), Expect = 1e-31
Identities = 68/149 (45%), Positives = 92/149 (61%)
Frame = +2
Query: 2 FKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVI 181
FKLL L ++ L + S EE H +P+ +V ++V E +G ITD S+YSLPS+V+
Sbjct: 303 FKLLTTSLKQYSLAPVYNSEEELAHALVPKKGVVYSYVAENQNGKITDFVSFYSLPSTVM 362
Query: 182 DNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKF 361
+ H + AAY +Y VA T L+ D+LI A E FDVFNAL++M N++ +LKF
Sbjct: 363 GHTTHKTIYAAYLYYYVAGSVTPK-QLINDSLILANREKFDVFNALDLMHNEKIFSDLKF 421
Query: 362 GPGDGQLHYYLYNWQCPQMNSGDVALVLQ 448
G GDG L YYLYNW+C M + LVLQ
Sbjct: 422 GKGDGNLQYYLYNWKCADMKPSQIGLVLQ 450
>sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 466
Score = 116 bits (290), Expect = 4e-26
Identities = 69/159 (43%), Positives = 99/159 (62%), Gaps = 19/159 (11%)
Frame = +2
Query: 8 LLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVS-----TFVVEQPDGT-ITDMCSYYSLP 169
LL+ Y+ +F+L A S EE HWF+ + S ++VVE P+ ITD S+YSLP
Sbjct: 289 LLSQYMERFEL-AHLFSEEEVRHWFLYTDKVSSGPVVWSYVVENPESKKITDFFSFYSLP 347
Query: 170 SSVIDNPHHSKLCAAYSFY--------NVASE-KTGWIP----LMRDALIQAKSEGFDVF 310
S+VI NP + + AAY +Y +++SE + ++ ++ DALI AK FDVF
Sbjct: 348 STVIGNPKYKDIQAAYLYYYASDSCPKDLSSESQLAFVERCKLIVNDALILAKKFHFDVF 407
Query: 311 NALNVMDNKEFLKELKFGPGDGQLHYYLYNWQCPQMNSG 427
NA+ V+DN FLK+LKFG GDG L+YY+YN+ CP++ G
Sbjct: 408 NAVTVLDNNLFLKDLKFGEGDGFLNYYIYNYNCPKIPGG 446
>sp|Q9UVX3|NMT_ASPFU Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 492
Score = 115 bits (289), Expect = 5e-26
Identities = 68/155 (43%), Positives = 92/155 (59%), Gaps = 15/155 (9%)
Frame = +2
Query: 8 LLNDYLNKFKLRAEFGSLEEFEHWFMPRLN-----IVSTFVVEQPDG-TITDMCSYYSLP 169
LL YL++F L F + EE +HW + + +V +VVE P+ ITD S+Y+L
Sbjct: 319 LLQRYLSRFALNQAF-TREEVDHWLVHKPETVKEQVVWAYVVEDPETHKITDFFSFYNLE 377
Query: 170 SSVIDNPHHSKLCAAYSFY---------NVASEKTGWIPLMRDALIQAKSEGFDVFNALN 322
S+VI NP H + AAY +Y N+ + K + LM DALI AK FDVFNAL
Sbjct: 378 STVIQNPKHDNVRAAYLYYYATETAFTNNMKALKERLLMLMNDALILAKKAHFDVFNALT 437
Query: 323 VMDNKEFLKELKFGPGDGQLHYYLYNWQCPQMNSG 427
+ DN FL++LKFG GDGQLH+YLYN++ + G
Sbjct: 438 LHDNPLFLEQLKFGAGDGQLHFYLYNYRTAPVPGG 472
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,996,026
Number of Sequences: 369166
Number of extensions: 1157312
Number of successful extensions: 2735
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2658
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2713
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3600891075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)