Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_E08
(544 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransfera... 171 8e-43
sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransfera... 171 1e-42
sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferas... 171 1e-42
sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransfera... 171 1e-42
sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransfera... 167 2e-41
sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransfera... 165 8e-41
sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransfera... 162 6e-40
sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoylt... 140 2e-33
sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoylt... 119 5e-27
sp|P34809|NMT_CRYNV Glycylpeptide N-tetradecanoyltransferas... 117 1e-26
>sp|O60551|NMT2_HUMAN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 171 bits (434), Expect = 8e-43
Identities = 87/154 (56%), Positives = 111/154 (72%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D +L+N YL +F L A EE HWF+PR +I+ TFVVE P+G +TD S+Y+L
Sbjct: 347 DIKSVRELINTYLKQFHL-APVMDEEEVAHWFLpreHIIDTFVVESPNGKLTDFLSFYTL 405
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PS+V+ +P H L AAYSFYN+ +E T + LM DALI AKS+GFDVFNAL++M+NK FL
Sbjct: 406 PSTVMHHPAHKSLKAAYSFYNIHTE-TPLLDLMSDALILAKSKGFDVFNALDLMENKTFL 464
Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
++LKFG GDG L YYLYNW+CP +S V LVLQ
Sbjct: 465 EKLKFGIGDGNLQYYLYNWRCPGTDSEKVGLVLQ 498
>sp|P30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 171 bits (433), Expect = 1e-42
Identities = 85/154 (55%), Positives = 110/154 (71%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D P +LL YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+L
Sbjct: 345 DIPVVHQLLTRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL
Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462
Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
++LKFG GDG L YYLYNW+CP M + V LVLQ
Sbjct: 463 EKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|O61613|NMT_DROME Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT) (dNMT)
Length = 472
Score = 171 bits (433), Expect = 1e-42
Identities = 84/153 (54%), Positives = 106/153 (69%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D +A KLL DYL +F+L F S EEF HWF P+ I+ FVV G ITD+ SYY L
Sbjct: 321 DMDKAHKLLEDYLKRFQLSPVF-SKEEFRHWFTPKEGIIDCFVVADEKGNITDLTSYYCL 379
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PSSV+ +P H + AAYSFYNV S KT W+ LM DALI A++ DV+NAL++M+NK++
Sbjct: 380 PSSVMHHPVHKTVRAAYSFYNV-STKTPWLDLMNDALISARNVQMDVYNALDLMENKKYF 438
Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVL 459
LKFG GDG L YYLYNW+CP M ++AL+L
Sbjct: 439 APLKFGAGDGNLQYYLYNWRCPSMQPEEIALIL 471
>sp|O70310|NMT1_MOUSE Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 496
Score = 171 bits (432), Expect = 1e-42
Identities = 84/154 (54%), Positives = 110/154 (71%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D P +LL+ YL +F L EE EHWF P+ NI+ TFVVE +G +TD S+Y+L
Sbjct: 345 DIPVVHQLLSRYLKQFHLTPVMNQ-EEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL
Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462
Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
++LKFG GDG L YYLYNW+CP M + V LVLQ
Sbjct: 463 EKLKFGIGDGNLQYYLYNWKCPSMGAEKVGLVLQ 496
>sp|P31717|NMT1_BOVIN Glycylpeptide N-tetradecanoyltransferase 1 (Peptide
N-myristoyltransferase 1) (Myristoyl-CoA:protein
N-myristoyltransferase 1) (NMT 1) (Type I
N-myristoyltransferase)
Length = 497
Score = 167 bits (422), Expect = 2e-41
Identities = 85/155 (54%), Positives = 111/155 (71%), Gaps = 1/155 (0%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D P +LL+ YL +F L S EE EHWF P+ NI+ TFVVE +G +TD S+Y+L
Sbjct: 345 DIPVVHQLLSRYLKQFHLTPVM-SQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTL 403
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PS+++++P H L AAYSFYNV ++ T + LM DAL+ AK +GFDVFNAL++M+NK FL
Sbjct: 404 PSTIMNHPTHKSLKAAYSFYNVHTQ-TPLLDLMSDALVLAKMKGFDVFNALDLMENKTFL 462
Query: 361 KELKFGPGDG-QLHYYLYNWQCPQMNSGDVALVLQ 462
++LKFG GDG L YYLYNW+CP M + V LVLQ
Sbjct: 463 EKLKFGIGDGNNLQYYLYNWKCPSMGAEKVGLVLQ 497
>sp|O70311|NMT2_MOUSE Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 529
Score = 165 bits (417), Expect = 8e-41
Identities = 83/148 (56%), Positives = 106/148 (71%)
Frame = +1
Query: 19 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 198
+L+N YL +F L E HWF+PR +I+ TFVVE P G +TD S+Y+LPS+V+
Sbjct: 384 ELINIYLKQFHLAPVMDDAE-VAHWFLpreHIIDTFVVENPSGKLTDFLSFYTLPSTVMH 442
Query: 199 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 378
+P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 443 HPAHKSLKAAYSFYNIHTE-TPLLDLMNDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 501
Query: 379 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
GDG L YYLYNW+CP +S V LVLQ
Sbjct: 502 IGDGNLQYYLYNWRCPGTDSEKVGLVLQ 529
>sp|Q9N181|NMT2_BOVIN Glycylpeptide N-tetradecanoyltransferase 2 (Peptide
N-myristoyltransferase 2) (Myristoyl-CoA:protein
N-myristoyltransferase 2) (NMT 2) (Type II
N-myristoyltransferase)
Length = 498
Score = 162 bits (409), Expect = 6e-40
Identities = 83/148 (56%), Positives = 105/148 (70%)
Frame = +1
Query: 19 KLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSLPSSVID 198
+L N YL +F L A EE HWF+P+ +I+ TFVVE G +TD S+Y+LPS+V+
Sbjct: 353 ELTNTYLKQFHL-APVMDEEEVAHWFLPQEHIIDTFVVENSSGKLTDFLSFYTLPSTVMH 411
Query: 199 NPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFG 378
+P H L AAYSFYN+ +E T + LM DALI AK +GFDVFNAL++M+NK FL++LKFG
Sbjct: 412 HPAHKSLKAAYSFYNIHTE-TPLLDLMSDALIIAKLKGFDVFNALDLMENKTFLEKLKFG 470
Query: 379 PGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
GDG L YYLYNW+CP S V LVLQ
Sbjct: 471 IGDGNLQYYLYNWRCPGTESEKVGLVLQ 498
>sp|P46548|NMT_CAEEL Probable glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 450
Score = 140 bits (354), Expect = 2e-33
Identities = 71/154 (46%), Positives = 95/154 (61%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVSTFVVEQPDGTITDMCSYYSL 180
D PQ FKLL L ++ L + S EE H +P+ +V ++V E +G ITD S+YSL
Sbjct: 298 DVPQVFKLLTTSLKQYSLAPVYNSEEELAHALVPKKGVVYSYVAENQNGKITDFVSFYSL 357
Query: 181 PSSVIDNPHHSKLCAAYSFYNVASEKTGWIPLMRDALIQAKSEGFDVFNALNVMDNKEFL 360
PS+V+ + H + AAY +Y VA T L+ D+LI A E FDVFNAL++M N++
Sbjct: 358 PSTVMGHTTHKTIYAAYLYYYVAGSVTPK-QLINDSLILANREKFDVFNALDLMHNEKIF 416
Query: 361 KELKFGPGDGQLHYYLYNWQCPQMNSGDVALVLQ 462
+LKFG GDG L YYLYNW+C M + LVLQ
Sbjct: 417 SDLKFGKGDGNLQYYLYNWKCADMKPSQIGLVLQ 450
>sp|O43010|NMT_SCHPO Probable glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 466
Score = 119 bits (298), Expect = 5e-27
Identities = 71/166 (42%), Positives = 101/166 (60%), Gaps = 19/166 (11%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLNIVS-----TFVVEQPDGT-ITDM 162
D P LL+ Y+ +F+L A S EE HWF+ + S ++VVE P+ ITD
Sbjct: 282 DVPAVQSLLSQYMERFEL-AHLFSEEEVRHWFLYTDKVSSGPVVWSYVVENPESKKITDF 340
Query: 163 CSYYSLPSSVIDNPHHSKLCAAYSFY--------NVASE-KTGWIP----LMRDALIQAK 303
S+YSLPS+VI NP + + AAY +Y +++SE + ++ ++ DALI AK
Sbjct: 341 FSFYSLPSTVIGNPKYKDIQAAYLYYYASDSCPKDLSSESQLAFVERCKLIVNDALILAK 400
Query: 304 SEGFDVFNALNVMDNKEFLKELKFGPGDGQLHYYLYNWQCPQMNSG 441
FDVFNA+ V+DN FLK+LKFG GDG L+YY+YN+ CP++ G
Sbjct: 401 KFHFDVFNAVTVLDNNLFLKDLKFGEGDGFLNYYIYNYNCPKIPGG 446
>sp|P34809|NMT_CRYNV Glycylpeptide N-tetradecanoyltransferase (Peptide
N-myristoyltransferase) (Myristoyl-CoA:protein
N-myristoyltransferase) (NMT)
Length = 598
Score = 117 bits (294), Expect = 1e-26
Identities = 74/196 (37%), Positives = 97/196 (49%), Gaps = 49/196 (25%)
Frame = +1
Query: 1 DCPQAFKLLNDYLNKFKLRAEFGSLEEFEHWFMPRLN----------IVSTFVVEQPDG- 147
D PQ LL YL++F + F +E EHWF+ +V +VVE P
Sbjct: 386 DVPQVGALLRRYLDRFDVAQAFKDDDEVEHWFLSGQGKEVGGRRVEQVVWAYVVEDPTTH 445
Query: 148 TITDMCSYYSLPSSVIDNPHHSKLCAAYSFY-------------------------NVAS 252
ITD+ S+Y+LPS+++ +P H+ L AAY FY +VA+
Sbjct: 446 RITDLISFYALPSTIMKHPKHNLLNAAYMFYYATDVIFPPPSSSAHSDADVNAGESSVAA 505
Query: 253 EKTGWIP-------------LMRDALIQAKSEGFDVFNALNVMDNKEFLKELKFGPGDGQ 393
TG L D LI AK GFDVFNAL ++DN FL+E KFGPGDG
Sbjct: 506 VGTGGEDAKTKKKLETRLNALTADLLIIAKQAGFDVFNALTLLDNNMFLQEQKFGPGDGY 565
Query: 394 LHYYLYNWQCPQMNSG 441
L+YYLYNW C ++ G
Sbjct: 566 LNYYLYNWNCAPIDGG 581
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,836,956
Number of Sequences: 369166
Number of extensions: 1185196
Number of successful extensions: 2815
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2736
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2793
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3734833040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)