Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00375 (1498 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q7YR26|TOP1_CERAE DNA topoisomerase I 317 7e-86 sp|P11387|TOP1_HUMAN DNA topoisomerase I 316 1e-85 sp|Q9WUL0|TOP1_RAT DNA topoisomerase I 315 2e-85 sp|Q04750|TOP1_MOUSE DNA topoisomerase I 315 3e-85 sp|Q07050|TOP1_CRIGR DNA topoisomerase I 312 1e-84 sp|P30189|TOP1_DROME DNA topoisomerase I 293 9e-79 sp|Q969P6|TOP1M_HUMAN DNA topoisomerase I, mitochondrial pr... 292 2e-78 sp|P41512|TOP1_XENLA DNA topoisomerase I 291 3e-78 sp|P93119|TOP1_DAUCA DNA topoisomerase I 236 1e-61 sp|P30181|TOP1_ARATH DNA topoisomerase I 231 3e-60
>sp|Q7YR26|TOP1_CERAE DNA topoisomerase I Length = 767 Score = 317 bits (811), Expect = 7e-86 Identities = 164/280 (58%), Positives = 198/280 (70%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTVGCCSLRVEHI L + + EY+V+FDFLGKDSIRY N+V V K Sbjct: 488 ALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEK 547 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 548 RVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKEL 607 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T DEN+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K++ ++ + Sbjct: 608 TAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKEQLADARRDL 667 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ KD+ Q TDRE+NK +ALGTSKLNYLD Sbjct: 668 KSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLD 727 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRI++AWC K VP+ KIYNKTQ +KF WA+DM +DY+F Sbjct: 728 PRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 767
>sp|P11387|TOP1_HUMAN DNA topoisomerase I Length = 765 Score = 316 bits (810), Expect = 1e-85 Identities = 164/280 (58%), Positives = 198/280 (70%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTVGCCSLRVEHI L + + EY+V+FDFLGKDSIRY N+V V K Sbjct: 486 ALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFLGKDSIRYYNKVPVEK 545 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 546 RVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKEL 605 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T DEN+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K++ ++ + Sbjct: 606 TAPDENIPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQTKIDAKKEQLADARRDL 665 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ KD+ Q TDRE+NK +ALGTSKLNYLD Sbjct: 666 KSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLD 725 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRI++AWC K VP+ KIYNKTQ +KF WA+DM +DY+F Sbjct: 726 PRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMADEDYEF 765
>sp|Q9WUL0|TOP1_RAT DNA topoisomerase I Length = 767 Score = 315 bits (807), Expect = 2e-85 Identities = 164/280 (58%), Positives = 198/280 (70%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTVGCCSLRVEHI L + + EY+V+FDF GKDSIRY N+V V K Sbjct: 488 ALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEK 547 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 548 RVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKEL 607 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T DEN+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K + ++ ++ Sbjct: 608 TAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARKDL 667 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ KD+ Q TDRE+NK +ALGTSKLNYLD Sbjct: 668 KSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLD 727 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRI++AWC K VP+ KIYNKTQ +KF WA+DMT +DY+F Sbjct: 728 PRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
>sp|Q04750|TOP1_MOUSE DNA topoisomerase I Length = 767 Score = 315 bits (806), Expect = 3e-85 Identities = 164/280 (58%), Positives = 197/280 (70%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTVGCCSLRVEHI L + + EY+V+FDF GKDSIRY N+V V K Sbjct: 488 ALRAGNEKEEGETADTVGCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEK 547 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 548 RVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKEL 607 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T DEN+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K + ++ + Sbjct: 608 TAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDL 667 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ KD+ Q TDRE+NK +ALGTSKLNYLD Sbjct: 668 KSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLD 727 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRI++AWC K VP+ KIYNKTQ +KF WA+DMT +DY+F Sbjct: 728 PRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
>sp|Q07050|TOP1_CRIGR DNA topoisomerase I Length = 767 Score = 312 bits (800), Expect = 1e-84 Identities = 163/280 (58%), Positives = 196/280 (70%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTV CCSLRVEHI L + + EY+V+FDF GKDSIRY N+V V K Sbjct: 488 ALRAGNEKEEGETADTVSCCSLRVEHINLHPELDGQEYVVEFDFPGKDSIRYYNKVPVEK 547 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 548 RVFKNLQLFMENKQPEDDLFDRLNTGILNKHLQDLMEGLTAKVFRTYNASITLQQQLKEL 607 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T DEN+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K + ++ + Sbjct: 608 TAPDENVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQSKIDAKKDQLADARRDL 667 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ KD+ Q TDRE+NK +ALGTSKLNYLD Sbjct: 668 KSAKADAKVMKDAKTKKVVESKKKAVQRLEEQLMKLEVQATDREENKQIALGTSKLNYLD 727 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRI++AWC K VP+ KIYNKTQ +KF WA+DMT +DY+F Sbjct: 728 PRITVAWCKKWGVPIEKIYNKTQREKFAWAIDMTDEDYEF 767
>sp|P30189|TOP1_DROME DNA topoisomerase I Length = 972 Score = 293 bits (750), Expect = 9e-79 Identities = 159/287 (55%), Positives = 197/287 (68%), Gaps = 8/287 (2%) Frame = +1 Query: 1 ALRAGNEKGEDEADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPKK 180 ALRAGNEK ED+ADTVGCCSLRVEH+ L + N E +V FDF GKDSIRY NEV V K+ Sbjct: 709 ALRAGNEKDEDQADTVGCCSLRVEHVQLHKELNGKENVVVFDFPGKDSIRYYNEVEVEKR 768 Query: 181 VYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNKT 360 V+KNL F E K++GDDLFDRLNT LN++L++LM GLTAKVFRTYNAS TL+ +L T Sbjct: 769 VFKNLELFMEHKKEGDDLFDRLNTQVLNEHLKELMEGLTAKVFRTYNASKTLQSQLDLLT 828 Query: 361 NLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKI-------DKRKKEY- 516 + + K+LAYN ANR VA LCNHQR+VPK+ EKSMENL EKI +K + EY Sbjct: 829 DPSATVPEKLLAYNRANRAVAILCNHQRSVPKSHEKSMENLKEKIKAKREAIEKCESEYH 888 Query: 517 SEVKEQAKQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGT 696 S +++ KQL+ + K + Q+TDR++NK +ALGT Sbjct: 889 SRDEKKGKQLERLRDQLKKLEL-----------------------QETDRDENKTIALGT 925 Query: 697 SKLNYLDPRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 SKLNYLDPRIS+AWC K+ VP+ KI+NKTQ KF WAV M ++Y+F Sbjct: 926 SKLNYLDPRISVAWCKKHDVPIEKIFNKTQRTKFLWAVHMADENYRF 972
>sp|Q969P6|TOP1M_HUMAN DNA topoisomerase I, mitochondrial precursor (TOP1mt) Length = 601 Score = 292 bits (748), Expect = 2e-78 Identities = 149/280 (53%), Positives = 195/280 (69%), Gaps = 1/280 (0%) Frame = +1 Query: 1 ALRAGNEKGEDEA-DTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK + EA DTVGCCSLRVEH+ L + + +++V+FDFLGKD IRY N V V K Sbjct: 322 ALRAGNEKEDGEAADTVGCCSLRVEHVQLHPEADGCQHVVEFDFLGKDCIRYYNRVPVEK 381 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 VYKNL F E K DDLFDRL TT+LN++L++LM GLTAKVFRTYNASITL+ +L Sbjct: 382 PVYKNLQLFMENKDPRDDLFDRLTTTSLNKHLQELMDGLTAKVFRTYNASITLQEQLRAL 441 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 T +++++ K+L+YN ANR VA LCNHQRA P TFEKSM+NL KI +K++ +E + + Sbjct: 442 TRAEDSIAAKILSYNRANRVVAILCNHQRATPSTFEKSMQNLQTKIQAKKEQVAEARAEL 501 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 ++ ++E+ D Q TD+E+NK VALGTSKLNYLD Sbjct: 502 RRARAEHKAQGDGKSRSVLEKKRRLLEKLQEQLAQLSVQATDKEENKQVALGTSKLNYLD 561 Query: 718 PRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 PRISIAWC + +VP+ KIY+KTQ ++F WA+ M +D++F Sbjct: 562 PRISIAWCKRFRVPVEKIYSKTQRERFAWALAMAGEDFEF 601
>sp|P41512|TOP1_XENLA DNA topoisomerase I Length = 829 Score = 291 bits (746), Expect = 3e-78 Identities = 153/263 (58%), Positives = 185/263 (70%), Gaps = 1/263 (0%) Frame = +1 Query: 1 ALRAGNEKGEDE-ADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPK 177 ALRAGNEK E E ADTVGCCSLRVEHI L + + E++V+FDF GKDSIRY N+V V K Sbjct: 542 ALRAGNEKEEGETADTVGCCSLRVEHINLFQELDGQEFVVEFDFPGKDSIRYYNKVPVEK 601 Query: 178 KVYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNK 357 +V+KNL F E KQ DDLFDRLNT+ LN++L+DLM GLTAKVFRTYNASITL+++L Sbjct: 602 RVFKNLQLFMENKQPDDDLFDRLNTSILNKHLQDLMEGLTAKVFRTYNASITLQQQLDEL 661 Query: 358 TNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQA 537 TN D+N+ K+L+YN ANR VA LCNHQRA PKTFEKSM NL KID +K + ++ + + Sbjct: 662 TNSDDNVPAKILSYNRANRAVAILCNHQRAPPKTFEKSMMNLQGKIDAKKDQLADARREF 721 Query: 538 KQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQTDREKNKDVALGTSKLNYLD 717 K K++ +D Q TDRE+NK +ALGTSKLNYLD Sbjct: 722 KSAKADAKVRRDEKTKKLVESKKKAVQRIEEQLMKLEVQATDREENKQIALGTSKLNYLD 781 Query: 718 PRISIAWCLKNKVPLNKIYNKTQ 786 PRIS+AWC K VP+ KIYNKTQ Sbjct: 782 PRISVAWCKKYGVPIEKIYNKTQ 804
>sp|P93119|TOP1_DAUCA DNA topoisomerase I Length = 790 Score = 236 bits (603), Expect = 1e-61 Identities = 132/302 (43%), Positives = 185/302 (61%), Gaps = 30/302 (9%) Frame = +1 Query: 1 ALRAGNEKGEDEADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPKK 180 ALRAGNEK +DEADTVGCC+L+VE++ + PN I+KFDFLGKDSIRYQNEV V + Sbjct: 488 ALRAGNEKDDDEADTVGCCTLKVENVETKR-PN----ILKFDFLGKDSIRYQNEVEVEPR 542 Query: 181 VYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLER----EL 348 V+ + +F+ GK+ GDDLFD+L+T+ LN +L++LMPGLTAKVFRTYNASITL+ +L Sbjct: 543 VFSAIEQFRSGKEGGDDLFDQLDTSKLNAHLKELMPGLTAKVFRTYNASITLDEMVRCKL 602 Query: 349 VNKTNLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVK 528 +++ +++ KV+ Y AN+EVA +CNHQR V K+ M L EKI++ K E++ Sbjct: 603 LSRETKGGDVAEKVVVYQHANKEVAIICNHQRTVSKSHSAQMVRLNEKIEELKGLLKELQ 662 Query: 529 EQAKQLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQ------------------ 654 E ++ K+S + + Sbjct: 663 EDLTRVNKGKPPLKNSDGKPKRNLNLKRYKGKLLKLIQKLRKWSETRRLSVTKKIAQTNT 722 Query: 655 -----QTDREKNKD---VALGTSKLNYLDPRISIAWCLKNKVPLNKIYNKTQLQKFQWAV 810 + D+E +D VALGTSK+NYLDPRI++AWC ++ VP+ KI+NK+ L KF WA+ Sbjct: 723 KIEKMERDKETKEDLKTVALGTSKINYLDPRITVAWCKRHDVPIEKIFNKSLLAKFAWAM 782 Query: 811 DM 816 D+ Sbjct: 783 DV 784
>sp|P30181|TOP1_ARATH DNA topoisomerase I Length = 916 Score = 231 bits (590), Expect = 3e-60 Identities = 131/290 (45%), Positives = 181/290 (62%), Gaps = 11/290 (3%) Frame = +1 Query: 1 ALRAGNEKGEDEADTVGCCSLRVEHITLENDPNTDEYIVKFDFLGKDSIRYQNEVTVPKK 180 ALRAGNEK +DEADTVGCC+L+V ++ PN +KFDFLGKDSI+Y N V V Sbjct: 638 ALRAGNEKDDDEADTVGCCTLKVGNVECI-PPNK----IKFDFLGKDSIQYVNTVEVEPL 692 Query: 181 VYKNLLRFKEGKQDGDDLFDRLNTTTLNQYLRDLMPGLTAKVFRTYNASITLERELVNKT 360 VYK + +F+ GK DDLFD L+T+ LN +L++L+PGLTAKVFRTYNASITL+ E++++ Sbjct: 693 VYKAIGQFQAGKSKTDDLFDELDTSKLNAHLKELVPGLTAKVFRTYNASITLD-EMLSQE 751 Query: 361 NLDENLSNKVLAYNGANREVAKLCNHQRAVPKTFEKSMENLGEKIDKRKKEYSEVKEQAK 540 D +++ K++ Y AN+EVA +CNHQR V KT G +I+K E+KE K Sbjct: 752 TKDGDVTQKIVVYQKANKEVAIICNHQRTVSKTH-------GAQIEKLTARIEELKEVLK 804 Query: 541 QLKSEYSKTKDSGIXXXXXXXXXXXXXXXXXXXXXINQQT-----------DREKNKDVA 687 +LK+ + K I QQ+ +E K VA Sbjct: 805 ELKTNLDRAKKGKPPLEGSDGKKIRSLEPNAWEKKIAQQSAKIEKMERDMHTKEDLKTVA 864 Query: 688 LGTSKLNYLDPRISIAWCLKNKVPLNKIYNKTQLQKFQWAVDMTTKDYKF 837 LGTSK+NYLDPRI++AWC +++VP+ KI+ K+ L+KF WA+D+ +Y+F Sbjct: 865 LGTSKINYLDPRITVAWCKRHEVPIEKIFTKSLLEKFAWAMDV-EPEYRF 913
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 129,938,707 Number of Sequences: 369166 Number of extensions: 2153757 Number of successful extensions: 7191 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 6737 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 7146 length of database: 68,354,980 effective HSP length: 115 effective length of database: 47,110,455 effective search space used: 18043304265 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)