Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00364 (457 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xy... 44 1e-04 sp|P49927|PRIO_PIG Major prion protein precursor (PrP) 35 0.10 sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (P... 33 0.30 sp|Q01714|SP1_RAT Transcription factor Sp1 33 0.30 sp|O89090|SP1_MOUSE Transcription factor Sp1 33 0.30 sp|Q9UPQ9|TNC6B_HUMAN Trinucleotide repeat-containing 6B pr... 33 0.39 sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP) 32 0.51 sp|P67986|PRIO_CEREN Major prion protein precursor (PrP) >g... 32 0.51 sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP) 32 0.51 sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (P... 32 0.51
>sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xylA precursor Length = 954 Score = 44.3 bits (103), Expect = 1e-04 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Frame = +2 Query: 5 NNMAQNGNSINQHMGRSADMMPNPWDPQ-MWNPNHLTTSAMQPSQASNNGWGPMTNGGWD 181 NN QN N N G + N WD WN +Q NN W W+ Sbjct: 463 NNWNQNNNQQNAWNGWDNNNNWNQWDQNNQWN-----------NQQQNNTWDWNNQNNWN 511 Query: 182 QGHPNNQWNALSGFSMQTNSGNDWR--SNMSNGMN 280 NN WN + Q N NDW +N +N N Sbjct: 512 NNQQNNDWNQWNNQGQQQN--NDWNQWNNQNNNQN 544
Score = 41.2 bits (95), Expect = 0.001 Identities = 29/92 (31%), Positives = 38/92 (41%), Gaps = 3/92 (3%) Frame = +2 Query: 5 NNMAQNGNSINQHMGRSADMMP-NPWDPQM-WNPNHLTTSAMQPSQASNNGWGPMTNGGW 178 NN Q N NQ + N W+ Q WN N+ +A NGW N W Sbjct: 434 NNNQQQNNDWNQWNNQGQQNNDWNQWNNQNNWNQNNNQQNAW-------NGWD--NNNNW 484 Query: 179 DQGHPNNQW-NALSGFSMQTNSGNDWRSNMSN 271 +Q NNQW N + N+ N+W +N N Sbjct: 485 NQWDQNNQWNNQQQNNTWDWNNQNNWNNNQQN 516
Score = 41.2 bits (95), Expect = 0.001 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 9/106 (8%) Frame = +2 Query: 5 NNMAQNGNSINQHMGRSADMMPNPWD---PQMWNPNHLTTSAMQPSQASNNG--WGPMTN 169 NN Q N+ + N WD WN N+ +A +NN WG N Sbjct: 523 NNQGQQQNNDWNQWNNQNNNQNNGWDWNNQNNWNQNNNQQNAWNGWDNNNNWNQWGGQNN 582 Query: 170 GGWDQGHPNNQWNALSGFSMQTNSG----NDWRSNMSNGMNPSAAS 295 W+ NN WN + Q N+ N+W N N + +S Sbjct: 583 D-WNNQQQNNDWNQWNNQGQQQNNDWNNQNNWNQGQQNNNNSAGSS 627
Score = 38.1 bits (87), Expect = 0.009 Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 8/100 (8%) Frame = +2 Query: 5 NNMAQNGNSINQ--HMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQ------ASNNGWGP 160 NN Q N NQ + G+ + N W Q + N Q + NN W Sbjct: 292 NNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQ 351 Query: 161 MTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMN 280 N G Q NN WN + Q N N W + +N N Sbjct: 352 WNNQGQQQ---NNDWN---NWGQQNNDWNQWNNQNNNQQN 385
Score = 37.7 bits (86), Expect = 0.012 Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 10/99 (10%) Frame = +2 Query: 5 NNMAQNG----NSINQHMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNG 172 NN QN N+ N + N W+ Q N+ + NNGW Sbjct: 494 NNQQQNNTWDWNNQNNWNNNQQNNDWNQWNNQGQQQNNDWNQWNNQNNNQNNGWDWNNQN 553 Query: 173 GWDQGHPNNQWNALSGFSMQTN------SGNDWRSNMSN 271 W+Q NNQ NA +G+ N NDW + N Sbjct: 554 NWNQN--NNQQNAWNGWDNNNNWNQWGGQNNDWNNQQQN 590
Score = 37.0 bits (84), Expect = 0.021 Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Frame = +2 Query: 5 NNMAQNGNSINQHMGRSADMMP--NPWDPQM-WNPNHL--------TTSAMQPSQASNNG 151 NN Q N NQ ++ + N WD WN N+ + +Q NN Sbjct: 364 NNWGQQNNDWNQWNNQNNNQQNAWNGWDNNNNWNQNNQQQNNWDWNNQNNWNNNQQQNND 423 Query: 152 WGPMTN-GGWDQGHP-NNQWNALSGFSMQTNSGNDWRSNMSN 271 W N W+ NN WN + Q N N W +N +N Sbjct: 424 WNQWNNQNNWNNNQQQNNDWNQWNNQGQQNNDWNQW-NNQNN 464
Score = 34.7 bits (78), Expect = 0.10 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 4/89 (4%) Frame = +2 Query: 5 NNMAQNGNSINQHMGRSAD----MMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNG 172 +N + N S++ G S+D N W+ Q N N + NN W N Sbjct: 227 SNGSANVKSVSVTQGGSSDNGGQQQNNDWNQQ--NNNQQQNNDWNNWGQQNNDWNQWNN- 283 Query: 173 GWDQGHPNNQWNALSGFSMQTNSGNDWRS 259 QG NN WN + Q N N W + Sbjct: 284 ---QGQQNNDWN---NWGQQNNDWNQWNN 306
Score = 33.9 bits (76), Expect = 0.17 Identities = 24/100 (24%), Positives = 36/100 (36%), Gaps = 8/100 (8%) Frame = +2 Query: 5 NNMAQNGNSINQ--HMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQ------ASNNGWGP 160 NN Q N NQ + G+ + N W Q + N Q + NN W Sbjct: 316 NNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQ 375 Query: 161 MTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMN 280 N +Q + N W+ + ++ N+W N N N Sbjct: 376 WNNQNNNQQNAWNGWDNNNNWNQNNQQQNNWDWNNQNNWN 415
>sp|P49927|PRIO_PIG Major prion protein precursor (PrP) Length = 257 Score = 34.7 bits (78), Expect = 0.10 Identities = 17/53 (32%), Positives = 22/53 (41%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292 Q GWG GGW Q H W G Q N + ++NM + +AA Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWNKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 7.3 Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%) Frame = +2 Query: 92 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 265 WN T + P Q S G + P GGW Q H W G G W Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88 Query: 266 SNGMNPSAASMHGQ 307 G HGQ Sbjct: 89 GGGGWGQGGGSHGQ 102
>sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) Length = 252 Score = 33.1 bits (74), Expect = 0.30 Identities = 12/24 (50%), Positives = 13/24 (54%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQW 205 Q GWG GGW QG +NQW Sbjct: 75 QPHGGGWGQPHGGGWGQGGTHNQW 98
>sp|Q01714|SP1_RAT Transcription factor Sp1 Length = 786 Score = 33.1 bits (74), Expect = 0.30 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Frame = +2 Query: 14 AQNGNSINQHMGRSADMMPNPWD------PQMWNPNHLTTSAMQPSQASNNGWGPMTNGG 175 + G+S + G + P+P ++ +PN + ++ PSQ+ G +T Sbjct: 41 SSTGSSSSSGGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQ 100 Query: 176 WDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAAS 295 QG N W +S S T + + N +NG N S +S Sbjct: 101 LSQGA--NGWQIISSSSGATPTSKEQSGNSTNGSNGSESS 138
>sp|O89090|SP1_MOUSE Transcription factor Sp1 Length = 784 Score = 33.1 bits (74), Expect = 0.30 Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%) Frame = +2 Query: 14 AQNGNSINQHMGRSADMMPNPWD------PQMWNPNHLTTSAMQPSQASNNGWGPMTNGG 175 + G+S + G + P+P ++ +PN + ++ PSQ+ G +T Sbjct: 42 SSTGSSSSSGGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQ 101 Query: 176 WDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAAS 295 QG N W +S S T + + N +NG N S +S Sbjct: 102 LSQGA--NGWQIISSSSGATPTSKEQSGNSTNGSNGSESS 139
>sp|Q9UPQ9|TNC6B_HUMAN Trinucleotide repeat-containing 6B protein Length = 1723 Score = 32.7 bits (73), Expect = 0.39 Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 4/105 (3%) Frame = +2 Query: 2 GNNMAQNGNSINQHMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWD 181 G N +N NS N GR P+ P WN N + N GW NG + Sbjct: 697 GWNDYKNNNSSNWGGGR-----PDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGE 751 Query: 182 Q--GHPNNQW--NALSGFSMQTNSGNDWRSNMSNGMNPSAASMHG 304 + N+ W +A S G + NG N S AS G Sbjct: 752 EVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGG 796
>sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP) Length = 256 Score = 32.3 bits (72), Expect = 0.51 Identities = 17/53 (32%), Positives = 22/53 (41%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292 Q GWG GGW Q H W G Q N + ++NM + +AA Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P67986|PRIO_CEREN Major prion protein precursor (PrP) sp|P67987|PRIO_CEREL Major prion protein precursor (PrP) Length = 256 Score = 32.3 bits (72), Expect = 0.51 Identities = 17/53 (32%), Positives = 22/53 (41%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292 Q GWG GGW Q H W G Q N + ++NM + +AA Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGTHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP) Length = 256 Score = 32.3 bits (72), Expect = 0.51 Identities = 17/53 (32%), Positives = 22/53 (41%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292 Q GWG GGW Q H W G Q N + ++NM + +AA Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C) Length = 257 Score = 32.3 bits (72), Expect = 0.51 Identities = 16/53 (30%), Positives = 21/53 (39%) Frame = +2 Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292 Q GWG GGW Q H W G Q + ++NM + +AA Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWGKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 7.3 Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%) Frame = +2 Query: 92 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 265 WN T + P Q S G + P GGW Q H W G G W Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88 Query: 266 SNGMNPSAASMHGQ 307 G HGQ Sbjct: 89 GGGGWGQGGGSHGQ 102
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,784,087 Number of Sequences: 369166 Number of extensions: 1161734 Number of successful extensions: 3340 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2980 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3199 length of database: 68,354,980 effective HSP length: 101 effective length of database: 49,696,745 effective search space used: 2484837250 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)