Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_D13
(390 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xy... 39 0.005
sp|P49927|PRIO_PIG Major prion protein precursor (PrP) 35 0.069
sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (P... 33 0.20
sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP) 32 0.34
sp|P67986|PRIO_CEREN Major prion protein precursor (PrP) >g... 32 0.34
sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP) 32 0.34
sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (P... 32 0.34
sp|Q95M08|PRIO_BUDTA Major prion protein precursor (PrP) 32 0.34
sp|Q7JK02|PRIO_OVIMU Major prion protein precursor (PrP) >g... 32 0.34
sp|P47852|PRIO_ODOHE Major prion protein precursor (PrP) 32 0.34
>sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xylA precursor
Length = 954
Score = 38.5 bits (88), Expect = 0.005
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 2/69 (2%)
Frame = +1
Query: 7 NPWDPQM-WNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQW-NALSGFSMQTNSG 180
N W+ Q WN N+ +A NGW N W+Q NNQW N + N+
Sbjct: 457 NQWNNQNNWNQNNNQQNAW-------NGWD--NNNNWNQWDQNNQWNNQQQNNTWDWNNQ 507
Query: 181 NDWRSNMSN 207
N+W +N N
Sbjct: 508 NNWNNNQQN 516
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 9/84 (10%)
Frame = +1
Query: 7 NPWD---PQMWNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQT 171
N WD WN N+ +A +NN WG N W+ NN WN + Q
Sbjct: 545 NGWDWNNQNNWNQNNNQQNAWNGWDNNNNWNQWGGQNND-WNNQQQNNDWNQWNNQGQQQ 603
Query: 172 NSG----NDWRSNMSNGMNPSAAS 231
N+ N+W N N + +S
Sbjct: 604 NNDWNNQNNWNQGQQNNNNSAGSS 627
Score = 37.4 bits (85), Expect = 0.011
Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 3/73 (4%)
Frame = +1
Query: 7 NPWDPQ-MWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGN 183
N WD WN +Q NN W W+ NN WN + Q N N
Sbjct: 485 NQWDQNNQWN-----------NQQQNNTWDWNNQNNWNNNQQNNDWNQWNNQGQQQN--N 531
Query: 184 DWR--SNMSNGMN 216
DW +N +N N
Sbjct: 532 DWNQWNNQNNNQN 544
Score = 36.2 bits (82), Expect = 0.024
Identities = 21/73 (28%), Positives = 28/73 (38%), Gaps = 6/73 (8%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTN---- 174
N W+ Q N+ + NNGW W+Q NNQ NA +G+ N
Sbjct: 520 NQWNNQGQQQNNDWNQWNNQNNNQNNGWDWNNQNNWNQN--NNQQNAWNGWDNNNNWNQW 577
Query: 175 --SGNDWRSNMSN 207
NDW + N
Sbjct: 578 GGQNNDWNNQQQN 590
Score = 33.9 bits (76), Expect = 0.12
Identities = 22/67 (32%), Positives = 29/67 (43%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGND 186
N WD WN + + Q NN W N G Q NN WN + + N+G D
Sbjct: 500 NTWD---WNNQNNWNNNQQ-----NNDWNQWNNQGQQQ---NNDWNQWNNQNNNQNNGWD 548
Query: 187 WRSNMSN 207
W +N +N
Sbjct: 549 W-NNQNN 554
Score = 33.5 bits (75), Expect = 0.15
Identities = 20/62 (32%), Positives = 25/62 (40%), Gaps = 1/62 (1%)
Frame = +1
Query: 7 NPWDPQM-WNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGN 183
N W+ Q WN N Q NN W N G Q + NQWN + ++ N N
Sbjct: 425 NQWNNQNNWNNN----------QQQNNDWNQWNNQG-QQNNDWNQWNNQNNWNQNNNQQN 473
Query: 184 DW 189
W
Sbjct: 474 AW 475
Score = 33.1 bits (74), Expect = 0.20
Identities = 21/69 (30%), Positives = 28/69 (40%), Gaps = 2/69 (2%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTN-GGWDQGHP-NNQWNALSGFSMQTNSG 180
N WD WN + + +Q NN W N W+ NN WN + Q N
Sbjct: 404 NNWD---WNNQNNWNN----NQQQNNDWNQWNNQNNWNNNQQQNNDWNQWNNQGQQNNDW 456
Query: 181 NDWRSNMSN 207
N W +N +N
Sbjct: 457 NQW-NNQNN 464
Score = 32.0 bits (71), Expect = 0.45
Identities = 22/75 (29%), Positives = 29/75 (38%), Gaps = 5/75 (6%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGH-----PNNQWNALSGFSMQT 171
N W Q + N Q + NN WG N W+Q + NN WN + Q
Sbjct: 316 NNWGQQNNDWNQWNNQGQQQNNDWNN-WGQQNND-WNQWNNQGQQQNNDWNN---WGQQN 370
Query: 172 NSGNDWRSNMSNGMN 216
N N W + +N N
Sbjct: 371 NDWNQWNNQNNNQQN 385
Score = 31.6 bits (70), Expect = 0.58
Identities = 15/46 (32%), Positives = 18/46 (39%), Gaps = 6/46 (13%)
Frame = +1
Query: 70 QASNNGWGPMTNG-----GWDQ-GHPNNQWNALSGFSMQTNSGNDW 189
Q NN W N W+ G NN WN + Q N N+W
Sbjct: 249 QQQNNDWNQQNNNQQQNNDWNNWGQQNNDWNQWNNQGQQNNDWNNW 294
Score = 31.2 bits (69), Expect = 0.76
Identities = 19/63 (30%), Positives = 23/63 (36%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGND 186
N W+ Q N N + NN W N QG NN WN + Q N N
Sbjct: 253 NDWNQQ--NNNQQQNNDWNNWGQQNNDWNQWNN----QGQQNNDWN---NWGQQNNDWNQ 303
Query: 187 WRS 195
W +
Sbjct: 304 WNN 306
Score = 31.2 bits (69), Expect = 0.76
Identities = 20/70 (28%), Positives = 24/70 (34%), Gaps = 7/70 (10%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQ-------GHPNNQWNALSGFSM 165
N W+ WN + NN W N G Q G NN WN +
Sbjct: 276 NDWN--QWNNQGQQNNDWNNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQWNNQGQ 333
Query: 166 QTNSGNDWRS 195
Q N NDW +
Sbjct: 334 QQN--NDWNN 341
Score = 30.0 bits (66), Expect = 1.7
Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Frame = +1
Query: 7 NPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWDQ--GHPNNQWNALSGFSMQTNSG 180
N W Q + N Q + NN WG N W+Q NNQ NA +G+ ++
Sbjct: 340 NNWGQQNNDWNQWNNQGQQQNNDWNN-WGQQNND-WNQWNNQNNNQQNAWNGW----DNN 393
Query: 181 NDWRSN 198
N+W N
Sbjct: 394 NNWNQN 399
Score = 29.3 bits (64), Expect = 2.9
Identities = 19/71 (26%), Positives = 26/71 (36%), Gaps = 3/71 (4%)
Frame = +1
Query: 7 NPWDPQM-WNPNHLTTSAMQPSQASNNGWGPMTN--GGWDQGHPNNQWNALSGFSMQTNS 177
N WD WN N+ Q +N W N Q + NQWN + ++
Sbjct: 388 NGWDNNNNWNQNN--------QQQNNWDWNNQNNWNNNQQQNNDWNQWNNQNNWNNNQQQ 439
Query: 178 GNDWRSNMSNG 210
NDW + G
Sbjct: 440 NNDWNQWNNQG 450
Score = 27.7 bits (60), Expect = 8.4
Identities = 12/46 (26%), Positives = 19/46 (41%)
Frame = +1
Query: 79 NNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMN 216
NN W N +Q + N W+ + ++ N+W N N N
Sbjct: 370 NNDWNQWNNQNNNQQNAWNGWDNNNNWNQNNQQQNNWDWNNQNNWN 415
>sp|P49927|PRIO_PIG Major prion protein precursor (PrP)
Length = 257
Score = 34.7 bits (78), Expect = 0.069
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWNKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 4.9
Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%)
Frame = +1
Query: 28 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 201
WN T + P Q S G + P GGW Q H W G G W
Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88
Query: 202 SNGMNPSAASMHGQ 243
G HGQ
Sbjct: 89 GGGGWGQGGGSHGQ 102
>sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)
Length = 252
Score = 33.1 bits (74), Expect = 0.20
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQW 141
Q GWG GGW QG +NQW
Sbjct: 75 QPHGGGWGQPHGGGWGQGGTHNQW 98
Score = 27.7 bits (60), Expect = 8.4
Identities = 13/40 (32%), Positives = 14/40 (35%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDW 189
Q GWG GGW Q H G Q + N W
Sbjct: 59 QPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGTHNQW 98
>sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P67986|PRIO_CEREN Major prion protein precursor (PrP)
sp|P67987|PRIO_CEREL Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGTHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)
Length = 257
Score = 32.3 bits (72), Expect = 0.34
Identities = 16/53 (30%), Positives = 21/53 (39%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWGKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 4.9
Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%)
Frame = +1
Query: 28 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 201
WN T + P Q S G + P GGW Q H W G G W
Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88
Query: 202 SNGMNPSAASMHGQ 243
G HGQ
Sbjct: 89 GGGGWGQGGGSHGQ 102
>sp|Q95M08|PRIO_BUDTA Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|Q7JK02|PRIO_OVIMU Major prion protein precursor (PrP)
sp|Q7JIY2|PRIO_OVIMO Major prion protein precursor (PrP)
sp|Q7JIH3|PRIO_OVICA Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P47852|PRIO_ODOHE Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.34
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +1
Query: 70 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 228
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGTHSQWNKPSKPKTNMKHVAGAAAA 121
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,097,040
Number of Sequences: 369166
Number of extensions: 916312
Number of successful extensions: 2683
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2355
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2561
length of database: 68,354,980
effective HSP length: 96
effective length of database: 50,620,420
effective search space used: 1670473860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)