Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_K19
(457 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xy... 44 1e-04
sp|P49927|PRIO_PIG Major prion protein precursor (PrP) 35 0.10
sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (P... 33 0.30
sp|Q01714|SP1_RAT Transcription factor Sp1 33 0.30
sp|O89090|SP1_MOUSE Transcription factor Sp1 33 0.30
sp|Q9UPQ9|TNC6B_HUMAN Trinucleotide repeat-containing 6B pr... 33 0.39
sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP) 32 0.51
sp|P67986|PRIO_CEREN Major prion protein precursor (PrP) >g... 32 0.51
sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP) 32 0.51
sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (P... 32 0.51
>sp|P29126|XYNA_RUMFL Bifunctional endo-1,4-beta-xylanase xylA precursor
Length = 954
Score = 44.3 bits (103), Expect = 1e-04
Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 3/95 (3%)
Frame = +2
Query: 5 NNMAQNGNSINQHMGRSADMMPNPWDPQ-MWNPNHLTTSAMQPSQASNNGWGPMTNGGWD 181
NN QN N N G + N WD WN +Q NN W W+
Sbjct: 463 NNWNQNNNQQNAWNGWDNNNNWNQWDQNNQWN-----------NQQQNNTWDWNNQNNWN 511
Query: 182 QGHPNNQWNALSGFSMQTNSGNDWR--SNMSNGMN 280
NN WN + Q N NDW +N +N N
Sbjct: 512 NNQQNNDWNQWNNQGQQQN--NDWNQWNNQNNNQN 544
Score = 41.2 bits (95), Expect = 0.001
Identities = 29/92 (31%), Positives = 38/92 (41%), Gaps = 3/92 (3%)
Frame = +2
Query: 5 NNMAQNGNSINQHMGRSADMMP-NPWDPQM-WNPNHLTTSAMQPSQASNNGWGPMTNGGW 178
NN Q N NQ + N W+ Q WN N+ +A NGW N W
Sbjct: 434 NNNQQQNNDWNQWNNQGQQNNDWNQWNNQNNWNQNNNQQNAW-------NGWD--NNNNW 484
Query: 179 DQGHPNNQW-NALSGFSMQTNSGNDWRSNMSN 271
+Q NNQW N + N+ N+W +N N
Sbjct: 485 NQWDQNNQWNNQQQNNTWDWNNQNNWNNNQQN 516
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 9/106 (8%)
Frame = +2
Query: 5 NNMAQNGNSINQHMGRSADMMPNPWD---PQMWNPNHLTTSAMQPSQASNNG--WGPMTN 169
NN Q N+ + N WD WN N+ +A +NN WG N
Sbjct: 523 NNQGQQQNNDWNQWNNQNNNQNNGWDWNNQNNWNQNNNQQNAWNGWDNNNNWNQWGGQNN 582
Query: 170 GGWDQGHPNNQWNALSGFSMQTNSG----NDWRSNMSNGMNPSAAS 295
W+ NN WN + Q N+ N+W N N + +S
Sbjct: 583 D-WNNQQQNNDWNQWNNQGQQQNNDWNNQNNWNQGQQNNNNSAGSS 627
Score = 38.1 bits (87), Expect = 0.009
Identities = 28/100 (28%), Positives = 36/100 (36%), Gaps = 8/100 (8%)
Frame = +2
Query: 5 NNMAQNGNSINQ--HMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQ------ASNNGWGP 160
NN Q N NQ + G+ + N W Q + N Q + NN W
Sbjct: 292 NNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQ 351
Query: 161 MTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMN 280
N G Q NN WN + Q N N W + +N N
Sbjct: 352 WNNQGQQQ---NNDWN---NWGQQNNDWNQWNNQNNNQQN 385
Score = 37.7 bits (86), Expect = 0.012
Identities = 27/99 (27%), Positives = 36/99 (36%), Gaps = 10/99 (10%)
Frame = +2
Query: 5 NNMAQNG----NSINQHMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNG 172
NN QN N+ N + N W+ Q N+ + NNGW
Sbjct: 494 NNQQQNNTWDWNNQNNWNNNQQNNDWNQWNNQGQQQNNDWNQWNNQNNNQNNGWDWNNQN 553
Query: 173 GWDQGHPNNQWNALSGFSMQTN------SGNDWRSNMSN 271
W+Q NNQ NA +G+ N NDW + N
Sbjct: 554 NWNQN--NNQQNAWNGWDNNNNWNQWGGQNNDWNNQQQN 590
Score = 37.0 bits (84), Expect = 0.021
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 13/102 (12%)
Frame = +2
Query: 5 NNMAQNGNSINQHMGRSADMMP--NPWDPQM-WNPNHL--------TTSAMQPSQASNNG 151
NN Q N NQ ++ + N WD WN N+ + +Q NN
Sbjct: 364 NNWGQQNNDWNQWNNQNNNQQNAWNGWDNNNNWNQNNQQQNNWDWNNQNNWNNNQQQNND 423
Query: 152 WGPMTN-GGWDQGHP-NNQWNALSGFSMQTNSGNDWRSNMSN 271
W N W+ NN WN + Q N N W +N +N
Sbjct: 424 WNQWNNQNNWNNNQQQNNDWNQWNNQGQQNNDWNQW-NNQNN 464
Score = 34.7 bits (78), Expect = 0.10
Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 4/89 (4%)
Frame = +2
Query: 5 NNMAQNGNSINQHMGRSAD----MMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNG 172
+N + N S++ G S+D N W+ Q N N + NN W N
Sbjct: 227 SNGSANVKSVSVTQGGSSDNGGQQQNNDWNQQ--NNNQQQNNDWNNWGQQNNDWNQWNN- 283
Query: 173 GWDQGHPNNQWNALSGFSMQTNSGNDWRS 259
QG NN WN + Q N N W +
Sbjct: 284 ---QGQQNNDWN---NWGQQNNDWNQWNN 306
Score = 33.9 bits (76), Expect = 0.17
Identities = 24/100 (24%), Positives = 36/100 (36%), Gaps = 8/100 (8%)
Frame = +2
Query: 5 NNMAQNGNSINQ--HMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQ------ASNNGWGP 160
NN Q N NQ + G+ + N W Q + N Q + NN W
Sbjct: 316 NNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQWNNQGQQQNNDWNNWGQQNNDWNQ 375
Query: 161 MTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMN 280
N +Q + N W+ + ++ N+W N N N
Sbjct: 376 WNNQNNNQQNAWNGWDNNNNWNQNNQQQNNWDWNNQNNWN 415
>sp|P49927|PRIO_PIG Major prion protein precursor (PrP)
Length = 257
Score = 34.7 bits (78), Expect = 0.10
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWNKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 7.3
Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%)
Frame = +2
Query: 92 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 265
WN T + P Q S G + P GGW Q H W G G W
Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88
Query: 266 SNGMNPSAASMHGQ 307
G HGQ
Sbjct: 89 GGGGWGQGGGSHGQ 102
>sp|Q95211|PRIO_RABIT Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)
Length = 252
Score = 33.1 bits (74), Expect = 0.30
Identities = 12/24 (50%), Positives = 13/24 (54%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQW 205
Q GWG GGW QG +NQW
Sbjct: 75 QPHGGGWGQPHGGGWGQGGTHNQW 98
>sp|Q01714|SP1_RAT Transcription factor Sp1
Length = 786
Score = 33.1 bits (74), Expect = 0.30
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Frame = +2
Query: 14 AQNGNSINQHMGRSADMMPNPWD------PQMWNPNHLTTSAMQPSQASNNGWGPMTNGG 175
+ G+S + G + P+P ++ +PN + ++ PSQ+ G +T
Sbjct: 41 SSTGSSSSSGGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQ 100
Query: 176 WDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAAS 295
QG N W +S S T + + N +NG N S +S
Sbjct: 101 LSQGA--NGWQIISSSSGATPTSKEQSGNSTNGSNGSESS 138
>sp|O89090|SP1_MOUSE Transcription factor Sp1
Length = 784
Score = 33.1 bits (74), Expect = 0.30
Identities = 25/100 (25%), Positives = 43/100 (43%), Gaps = 6/100 (6%)
Frame = +2
Query: 14 AQNGNSINQHMGRSADMMPNPWD------PQMWNPNHLTTSAMQPSQASNNGWGPMTNGG 175
+ G+S + G + P+P ++ +PN + ++ PSQ+ G +T
Sbjct: 42 SSTGSSSSSGGGGGQESQPSPLALLAATCSRIESPNENSNNSQGPSQSGGTGELDLTATQ 101
Query: 176 WDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAAS 295
QG N W +S S T + + N +NG N S +S
Sbjct: 102 LSQGA--NGWQIISSSSGATPTSKEQSGNSTNGSNGSESS 139
>sp|Q9UPQ9|TNC6B_HUMAN Trinucleotide repeat-containing 6B protein
Length = 1723
Score = 32.7 bits (73), Expect = 0.39
Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 4/105 (3%)
Frame = +2
Query: 2 GNNMAQNGNSINQHMGRSADMMPNPWDPQMWNPNHLTTSAMQPSQASNNGWGPMTNGGWD 181
G N +N NS N GR P+ P WN N + N GW NG +
Sbjct: 697 GWNDYKNNNSSNWGGGR-----PDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNGWGE 751
Query: 182 Q--GHPNNQW--NALSGFSMQTNSGNDWRSNMSNGMNPSAASMHG 304
+ N+ W +A S G + NG N S AS G
Sbjct: 752 EVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLASKGG 796
>sp|P52113|PRIO_CAPHI Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.51
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P67986|PRIO_CEREN Major prion protein precursor (PrP)
sp|P67987|PRIO_CEREL Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.51
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGTHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P23907|PRIO_SHEEP Major prion protein precursor (PrP)
Length = 256
Score = 32.3 bits (72), Expect = 0.51
Identities = 17/53 (32%), Positives = 22/53 (41%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292
Q GWG GGW Q H W G Q N + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQ-GGSHSQWNKPSKPKTNMKHVAGAAAA 121
>sp|P52114|PRIO_MUSPF Major prion protein precursor (PrP) (PrP27-30) (PrP33-35C)
Length = 257
Score = 32.3 bits (72), Expect = 0.51
Identities = 16/53 (30%), Positives = 21/53 (39%)
Frame = +2
Query: 134 QASNNGWGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNMSNGMNPSAA 292
Q GWG GGW Q H W G Q + ++NM + +AA
Sbjct: 70 QPHGGGWGQPHGGGWGQPHGGGGWGQGGGSHGQWGKPSKPKTNMKHVAGAAAA 122
Score = 28.5 bits (62), Expect = 7.3
Identities = 21/74 (28%), Positives = 23/74 (31%), Gaps = 2/74 (2%)
Frame = +2
Query: 92 WNPNHLTTSAMQPSQASNNG--WGPMTNGGWDQGHPNNQWNALSGFSMQTNSGNDWRSNM 265
WN T + P Q S G + P GGW Q H W G G W
Sbjct: 34 WN----TGGSRYPGQGSPGGNRYPPQGGGGWGQPH-GGGWGQPHGGGWGQPHGGGWGQPH 88
Query: 266 SNGMNPSAASMHGQ 307
G HGQ
Sbjct: 89 GGGGWGQGGGSHGQ 102
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,784,087
Number of Sequences: 369166
Number of extensions: 1161734
Number of successful extensions: 3340
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2980
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3199
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2484837250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)