Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00350 (978 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoaceta... 430 e-120 sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoaceta... 415 e-115 sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate... 409 e-114 sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoaceta... 280 6e-75 sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor bet... 32 2.1 sp|Q59050|YG56_METJA Hypothetical protein MJ1656 32 2.1 sp|O83729|Y747_TREPA Hypothetical protein TP0747 30 7.9 sp|Q8J0Q0|MNS1_CANAL Mannosyl-oligosaccharide 1,2-alpha-man... 30 7.9
>sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) Length = 419 Score = 430 bits (1106), Expect = e-120 Identities = 208/325 (64%), Positives = 243/325 (74%) Frame = +2 Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181 F + D RIGVAIG+QILDLS IKHLF G +L QDVF + +LN M LG++AW E Sbjct: 22 FSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEA 81 Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361 R +Q LLS+ LRDD ELRK AF+S +A MH+PA IGDYTDFYSS+ HA NVGIMF Sbjct: 82 RVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMF 141 Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541 R KENALMPNW LPVGYHGR+SS+VVSGTPI RP GQ KPDD+ P YG CK+LD ELE Sbjct: 142 RDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELE 201 Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721 MAFF GPGN+LG+PI ++ A ++IFG+VLMNDWSARDIQKWEYVPLGPFLGKSFGTT+SP Sbjct: 202 MAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSP 261 Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXX 901 WVVP+ AL PF + NP D L YL D+ +TFDINL V +K + Sbjct: 262 WVVPMDALMPFAVP-NPKQDPRPLPYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFK 320 Query: 902 YLYWTMKQQLVHHTVNGCNIQPGDL 976 Y+YWTM QQL HH+VNGCN++PGDL Sbjct: 321 YMYWTMLQQLTHHSVNGCNLRPGDL 345
>sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) Length = 419 Score = 415 bits (1066), Expect = e-115 Identities = 201/325 (61%), Positives = 241/325 (74%) Frame = +2 Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181 F + + RIGVAIG+QILDLS IKHLF G L Q VF E +LN M LG++AW E Sbjct: 22 FSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEA 81 Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361 R ++Q LLS LRDD ELR+ AF S +A MH+PA IGDYTDFYSS+ HA NVGIMF Sbjct: 82 RASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMF 141 Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541 RGKENAL+PNW LPVGYHGR+SSIVVSGTPI RP GQ +PD++ P YG C++LD ELE Sbjct: 142 RGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELE 201 Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721 MAFF GPGN+ G+PI ++ A ++IFG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISP Sbjct: 202 MAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISP 261 Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXX 901 WVVP+ AL PF++ NP D + L YL + +TFDINL V +K + Sbjct: 262 WVVPMDALMPFVVP-NPKQDPKPLPYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFK 320 Query: 902 YLYWTMKQQLVHHTVNGCNIQPGDL 976 ++YWTM QQL HH+VNGCN++PGDL Sbjct: 321 HMYWTMLQQLTHHSVNGCNLRPGDL 345
>sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) Length = 419 Score = 409 bits (1052), Expect = e-114 Identities = 199/325 (61%), Positives = 240/325 (73%) Frame = +2 Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181 F + + RIGVAIG+QILDLS IKHLF G +L Q VF E +LN M LG++AW E Sbjct: 22 FSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEA 81 Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361 R ++Q LLS LRDD ELR+ AF S +A MH+PA IGDYTDFYSS HA NVGIMF Sbjct: 82 RASLQNLLSASQAQLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMF 141 Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541 RGKENAL+PNW LPVGYHGR+SS+VVSGTPI RP GQ +PD++ P YG K LD ELE Sbjct: 142 RGKENALLPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELE 201 Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721 MAFF GPGN+ G+PI ++ A+++IFG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISP Sbjct: 202 MAFFVGPGNRFGEPIPISKAQEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISP 261 Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXX 901 WVVP+ AL PF++ NP D + L YL + +TFDINL V +K + Sbjct: 262 WVVPMDALMPFVVP-NPKQDPKPLPYLCHSQPYTFDINLSVALKGEGMSQAATICRSNFK 320 Query: 902 YLYWTMKQQLVHHTVNGCNIQPGDL 976 ++YWT+ QQL HH+VNGCN++PGDL Sbjct: 321 HMYWTILQQLTHHSVNGCNLRPGDL 345
>sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoacetate hydrolase) (Beta-diketonase) (FAA) Length = 431 Score = 280 bits (715), Expect = 6e-75 Identities = 156/324 (48%), Positives = 202/324 (62%), Gaps = 11/324 (3%) Frame = +2 Query: 38 VAIGEQILDLSKIKHLFKGSILKDFQ---DVFVEHSLNRIMSLGESAWNELRFTIQELLS 208 +AIG+ LDLSK S L Q +VF E +LN +LG ++R IQ++ S Sbjct: 35 IAIGDYALDLSKFASSGGFSQLPVIQPHLNVFKESTLNAFAALGRPVHRQVREYIQKVFS 94 Query: 209 MDCP---TLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENA 379 + P LRD+ L+K A + ++ H+P +IGDYTDFY+ +HA NVG++FRG +NA Sbjct: 95 TETPFPQILRDNAALQKEALLPLSEVTNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNA 154 Query: 380 LMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQ--TKPDDADK-PTYGPCKMLDFELEMAF 550 L PN+ LPV YHGR+SS+V SGTP+HRP GQ T P K PT+ PCK LD ELE+AF Sbjct: 155 LQPNYKHLPVAYHGRASSVVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAF 214 Query: 551 FTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVV 730 F N LG P+ ++ AE +IFGVVLMNDWSARDIQ WEYVPLGPF K+FGTTI+PWVV Sbjct: 215 FVSTPNDLGHPVHIDKAEDHIFGVVLMNDWSARDIQAWEYVPLGPFNAKNFGTTITPWVV 274 Query: 731 PIAALKPF-LLDYNPSHDHEDLDYLKDDKSFT-FDINLEVFIKPKDFXXXXXXXXXXXXY 904 I AL+PF + P + L YL++ ++ T +DI LEV + Sbjct: 275 LIDALEPFRTVGLEPGNRESLLPYLREKRADTAYDIPLEVEVTNAGGEPTVISRSNAKNL 334 Query: 905 LYWTMKQQLVHHTVNGCNIQPGDL 976 LY + Q L HHT+ GCN+ GDL Sbjct: 335 LY-SFPQMLAHHTITGCNLNTGDL 357
>sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor beta binding protein 4 precursor (LTBP-4) Length = 1666 Score = 32.3 bits (72), Expect = 2.1 Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Frame = -1 Query: 567 FPGPVKKAISSSKSNILQGPYVGLSASSGFV---CPHGR*IGVPD 442 FP P + + S + L PY GL A + CPHGR + VP+ Sbjct: 1551 FPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPE 1595
>sp|Q59050|YG56_METJA Hypothetical protein MJ1656 Length = 237 Score = 32.3 bits (72), Expect = 2.1 Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 11/71 (15%) Frame = +2 Query: 518 KMLDFELEMAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQ----KW------- 664 K +D+E+E+A G K + I + A I G ++ND +ARD+Q +W Sbjct: 86 KRVDYEVELAIVIG---KKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFD 142 Query: 665 EYVPLGPFLGK 697 + P+GP + K Sbjct: 143 TFCPIGPRIVK 153
>sp|O83729|Y747_TREPA Hypothetical protein TP0747 Length = 344 Score = 30.4 bits (67), Expect = 7.9 Identities = 19/51 (37%), Positives = 31/51 (60%) Frame = +2 Query: 5 QLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSL 157 ++KH SV + V+ GE+I DLSK+ FK F +VF+ S + +++L Sbjct: 295 KVKHGSVIQFAVS-GEEIKDLSKLSKYFKEGASSRF-EVFLHGSPDTVLNL 343
>sp|Q8J0Q0|MNS1_CANAL Mannosyl-oligosaccharide 1,2-alpha-mannosidase (Man(9)-alpha-mannosidase) Length = 565 Score = 30.4 bits (67), Expect = 7.9 Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 2/76 (2%) Frame = +2 Query: 626 LMNDWSARDIQKWEYVPLGPFL--GKSFGTTISPWVVPIAALKPFLLDYNPSHDHEDLDY 799 +++ W + W Y P G++ G W++ + +L ++ P D+ Sbjct: 46 ILDSWHTYEKYGWGYDVYHPIKQEGENMGPKPLGWMI-VDSLDTLMIMDCPEEVSRARDW 104 Query: 800 LKDDKSFTFDINLEVF 847 +K+D +TFD N+ F Sbjct: 105 IKNDLDYTFDYNVNTF 120
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 119,692,853 Number of Sequences: 369166 Number of extensions: 2615432 Number of successful extensions: 6108 Number of sequences better than 10.0: 8 Number of HSP's better than 10.0 without gapping: 5874 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6101 length of database: 68,354,980 effective HSP length: 111 effective length of database: 47,849,395 effective search space used: 10239770530 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)