Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_E24
(810 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoaceta... 371 e-102
sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoaceta... 360 3e-99
sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate... 356 5e-98
sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoaceta... 254 1e-67
sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor bet... 32 1.6
sp|Q59050|YG56_METJA Hypothetical protein MJ1656 32 1.6
sp|O83729|Y747_TREPA Hypothetical protein TP0747 30 6.0
sp|Q83DV5|GLPE_COXBU Thiosulfate sulfurtransferase glpE 30 7.8
sp|Q9ZLL2|MURC_HELPJ UDP-N-acetylmuramate--L-alanine ligase... 30 7.8
>sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 371 bits (953), Expect = e-102
Identities = 180/267 (67%), Positives = 207/267 (77%)
Frame = +2
Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181
F + D RIGVAIG+QILDLS IKHLF G +L QDVF + +LN M LG++AW E
Sbjct: 22 FSTRGDPRPRIGVAIGDQILDLSIIKHLFTGPVLSKHQDVFNQPTLNSFMGLGQAAWKEA 81
Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361
R +Q LLS+ LRDD ELRK AF+S +A MH+PA IGDYTDFYSS+ HA NVGIMF
Sbjct: 82 RVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPATIGDYTDFYSSRQHATNVGIMF 141
Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541
R KENALMPNW LPVGYHGR+SS+VVSGTPI RP GQ KPDD+ P YG CK+LD ELE
Sbjct: 142 RDKENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELE 201
Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721
MAFF GPGN+LG+PI ++ A ++IFG+VLMNDWSARDIQKWEYVPLGPFLGKSFGTT+SP
Sbjct: 202 MAFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSP 261
Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYL 802
WVVP+ AL PF + NP D L YL
Sbjct: 262 WVVPMDALMPFAVP-NPKQDPRPLPYL 287
>sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 360 bits (923), Expect = 3e-99
Identities = 175/267 (65%), Positives = 206/267 (77%)
Frame = +2
Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181
F + + RIGVAIG+QILDLS IKHLF G L Q VF E +LN M LG++AW E
Sbjct: 22 FSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPALSKHQHVFDETTLNNFMGLGQAAWKEA 81
Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361
R ++Q LLS LRDD ELR+ AF S +A MH+PA IGDYTDFYSS+ HA NVGIMF
Sbjct: 82 RASLQNLLSASQARLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMF 141
Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541
RGKENAL+PNW LPVGYHGR+SSIVVSGTPI RP GQ +PD++ P YG C++LD ELE
Sbjct: 142 RGKENALLPNWLHLPVGYHGRASSIVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELE 201
Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721
MAFF GPGN+ G+PI ++ A ++IFG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISP
Sbjct: 202 MAFFVGPGNRFGEPIPISKAHEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISP 261
Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYL 802
WVVP+ AL PF++ NP D + L YL
Sbjct: 262 WVVPMDALMPFVVP-NPKQDPKPLPYL 287
>sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 356 bits (913), Expect = 5e-98
Identities = 174/267 (65%), Positives = 205/267 (76%)
Frame = +2
Query: 2 FQLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSLGESAWNEL 181
F + + RIGVAIG+QILDLS IKHLF G +L Q VF E +LN M LG++AW E
Sbjct: 22 FSTQSNPKPRIGVAIGDQILDLSVIKHLFTGPVLSKHQHVFDETTLNSFMGLGQAAWKEA 81
Query: 182 RFTIQELLSMDCPTLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMF 361
R ++Q LLS LRDD ELR+ AF S +A MH+PA IGDYTDFYSS HA NVGIMF
Sbjct: 82 RASLQNLLSASQAQLRDDKELRQRAFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMF 141
Query: 362 RGKENALMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELE 541
RGKENAL+PNW LPVGYHGR+SS+VVSGTPI RP GQ +PD++ P YG K LD ELE
Sbjct: 142 RGKENALLPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELE 201
Query: 542 MAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISP 721
MAFF GPGN+ G+PI ++ A+++IFG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISP
Sbjct: 202 MAFFVGPGNRFGEPIPISKAQEHIFGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISP 261
Query: 722 WVVPIAALKPFLLDYNPSHDHEDLDYL 802
WVVP+ AL PF++ NP D + L YL
Sbjct: 262 WVVPMDALMPFVVP-NPKQDPKPLPYL 287
>sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 431
Score = 254 bits (650), Expect = 1e-67
Identities = 137/267 (51%), Positives = 176/267 (65%), Gaps = 10/267 (3%)
Frame = +2
Query: 38 VAIGEQILDLSKIKHLFKGSILKDFQ---DVFVEHSLNRIMSLGESAWNELRFTIQELLS 208
+AIG+ LDLSK S L Q +VF E +LN +LG ++R IQ++ S
Sbjct: 35 IAIGDYALDLSKFASSGGFSQLPVIQPHLNVFKESTLNAFAALGRPVHRQVREYIQKVFS 94
Query: 209 MDCP---TLRDDVELRKLAFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENA 379
+ P LRD+ L+K A + ++ H+P +IGDYTDFY+ +HA NVG++FRG +NA
Sbjct: 95 TETPFPQILRDNAALQKEALLPLSEVTNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNA 154
Query: 380 LMPNWTWLPVGYHGRSSSIVVSGTPIHRPCGQ--TKPDDADK-PTYGPCKMLDFELEMAF 550
L PN+ LPV YHGR+SS+V SGTP+HRP GQ T P K PT+ PCK LD ELE+AF
Sbjct: 155 LQPNYKHLPVAYHGRASSVVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAF 214
Query: 551 FTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVV 730
F N LG P+ ++ AE +IFGVVLMNDWSARDIQ WEYVPLGPF K+FGTTI+PWVV
Sbjct: 215 FVSTPNDLGHPVHIDKAEDHIFGVVLMNDWSARDIQAWEYVPLGPFNAKNFGTTITPWVV 274
Query: 731 PIAALKPF-LLDYNPSHDHEDLDYLKD 808
I AL+PF + P + L YL++
Sbjct: 275 LIDALEPFRTVGLEPGNRESLLPYLRE 301
>sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor beta binding protein 4 precursor
(LTBP-4)
Length = 1666
Score = 32.3 bits (72), Expect = 1.6
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Frame = -1
Query: 567 FPGPVKKAISSSKSNILQGPYVGLSASSGFV---CPHGR*IGVPD 442
FP P + + S + L PY GL A + CPHGR + VP+
Sbjct: 1551 FPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPE 1595
>sp|Q59050|YG56_METJA Hypothetical protein MJ1656
Length = 237
Score = 32.3 bits (72), Expect = 1.6
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 11/71 (15%)
Frame = +2
Query: 518 KMLDFELEMAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQ----KW------- 664
K +D+E+E+A G K + I + A I G ++ND +ARD+Q +W
Sbjct: 86 KRVDYEVELAIVIG---KKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFD 142
Query: 665 EYVPLGPFLGK 697
+ P+GP + K
Sbjct: 143 TFCPIGPRIVK 153
>sp|O83729|Y747_TREPA Hypothetical protein TP0747
Length = 344
Score = 30.4 bits (67), Expect = 6.0
Identities = 19/51 (37%), Positives = 31/51 (60%)
Frame = +2
Query: 5 QLKHDSVKRIGVAIGEQILDLSKIKHLFKGSILKDFQDVFVEHSLNRIMSL 157
++KH SV + V+ GE+I DLSK+ FK F +VF+ S + +++L
Sbjct: 295 KVKHGSVIQFAVS-GEEIKDLSKLSKYFKEGASSRF-EVFLHGSPDTVLNL 343
>sp|Q83DV5|GLPE_COXBU Thiosulfate sulfurtransferase glpE
Length = 107
Score = 30.0 bits (66), Expect = 7.8
Identities = 11/29 (37%), Positives = 20/29 (68%)
Frame = -2
Query: 704 QNFSPEMDQEEHIPIFEYHGLTSHSSEQH 618
Q +S + D+E+ + ++ YHG++S S QH
Sbjct: 48 QEYSEKADKEKPVLVYCYHGISSQSVAQH 76
>sp|Q9ZLL2|MURC_HELPJ UDP-N-acetylmuramate--L-alanine ligase
(UDP-N-acetylmuramoyl-L-alanine synthetase)
Length = 449
Score = 30.0 bits (66), Expect = 7.8
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Frame = -2
Query: 800 NNLNLHDHEKDYNPTEMVLTQL*VQPMEK*LYQNFSPEMDQEEHIPIFEYHGLTS--HSS 627
NNL L D + ++PTE+ T + +Y N QE+ I I++ H + +
Sbjct: 312 NNLILID-DYAHHPTEIGATLKSAR-----IYANLLNT--QEKIIVIWQAHKYSRLMDNL 363
Query: 626 EQHRKCFFPHCSSLLVDLTYFLVQ*KRP------FRVQSPTF 519
E+ +KCF HC L++ Y + KR F+ +PTF
Sbjct: 364 EEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKHYNPTF 405
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,812,187
Number of Sequences: 369166
Number of extensions: 2254387
Number of successful extensions: 5344
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5165
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5341
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)