Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_D20
(730 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoaceta... 345 9e-95
sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoaceta... 336 4e-92
sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate... 329 4e-90
sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoaceta... 248 1e-65
sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor bet... 32 1.3
sp|Q59050|YG56_METJA Hypothetical protein MJ1656 32 1.3
sp|Q8J0Q0|MNS1_CANAL Mannosyl-oligosaccharide 1,2-alpha-man... 30 5.0
sp|Q83DV5|GLPE_COXBU Thiosulfate sulfurtransferase glpE 30 6.6
sp|Q9ZLL2|MURC_HELPJ UDP-N-acetylmuramate--L-alanine ligase... 30 6.6
sp|Q8DD17|NUDC_VIBVU NADH pyrophosphatase 30 8.6
>sp|P16930|FAAA_HUMAN Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 345 bits (884), Expect = 9e-95
Identities = 161/241 (66%), Positives = 187/241 (77%)
Frame = +3
Query: 6 AFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENALMPNWTWLPVGYHGRSSS 185
AF+S +A MH+PA IGDYTDFYSS+ HA NVGIMFR KENALMPNW LPVGYHGR+SS
Sbjct: 106 AFISQASATMHLPATIGDYTDFYSSRQHATNVGIMFRDKENALMPNWLHLPVGYHGRASS 165
Query: 186 IVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELEMAFFTGPGNKLGQPITMNNAEKNI 365
+VVSGTPI RP GQ KPDD+ P YG CK+LD ELEMAFF GPGN+LG+PI ++ A ++I
Sbjct: 166 VVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEMAFFVGPGNRLGEPIPISKAHEHI 225
Query: 366 FGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPIAALKPFLLDYNPSHDHEDL 545
FG+VLMNDWSARDIQKWEYVPLGPFLGKSFGTT+SPWVVP+ AL PF + NP D L
Sbjct: 226 FGMVLMNDWSARDIQKWEYVPLGPFLGKSFGTTVSPWVVPMDALMPFAVP-NPKQDPRPL 284
Query: 546 DYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXXYLYWTMKQQLVHHTVNGCNIQPGD 725
YL D+ +TFDINL V +K + Y+YWTM QQL HH+VNGCN++PGD
Sbjct: 285 PYLCHDEPYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQLTHHSVNGCNLRPGD 344
Query: 726 L 728
L
Sbjct: 345 L 345
>sp|P35505|FAAA_MOUSE Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 336 bits (861), Expect = 4e-92
Identities = 156/241 (64%), Positives = 187/241 (77%)
Frame = +3
Query: 6 AFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENALMPNWTWLPVGYHGRSSS 185
AF S +A MH+PA IGDYTDFYSS+ HA NVGIMFRGKENAL+PNW LPVGYHGR+SS
Sbjct: 106 AFTSQASATMHLPATIGDYTDFYSSRQHATNVGIMFRGKENALLPNWLHLPVGYHGRASS 165
Query: 186 IVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELEMAFFTGPGNKLGQPITMNNAEKNI 365
IVVSGTPI RP GQ +PD++ P YG C++LD ELEMAFF GPGN+ G+PI ++ A ++I
Sbjct: 166 IVVSGTPIRRPMGQMRPDNSKPPVYGACRLLDMELEMAFFVGPGNRFGEPIPISKAHEHI 225
Query: 366 FGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPIAALKPFLLDYNPSHDHEDL 545
FG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISPWVVP+ AL PF++ NP D + L
Sbjct: 226 FGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVP-NPKQDPKPL 284
Query: 546 DYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXXYLYWTMKQQLVHHTVNGCNIQPGD 725
YL + +TFDINL V +K + ++YWTM QQL HH+VNGCN++PGD
Sbjct: 285 PYLCHSQPYTFDINLSVSLKGEGMSQAATICRSNFKHMYWTMLQQLTHHSVNGCNLRPGD 344
Query: 726 L 728
L
Sbjct: 345 L 345
>sp|P25093|FAAA_RAT Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 419
Score = 329 bits (844), Expect = 4e-90
Identities = 154/241 (63%), Positives = 185/241 (76%)
Frame = +3
Query: 6 AFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENALMPNWTWLPVGYHGRSSS 185
AF S +A MH+PA IGDYTDFYSS HA NVGIMFRGKENAL+PNW LPVGYHGR+SS
Sbjct: 106 AFTSQASATMHLPATIGDYTDFYSSLQHATNVGIMFRGKENALLPNWLHLPVGYHGRASS 165
Query: 186 IVVSGTPIHRPCGQTKPDDADKPTYGPCKMLDFELEMAFFTGPGNKLGQPITMNNAEKNI 365
+VVSGTPI RP GQ +PD++ P YG K LD ELEMAFF GPGN+ G+PI ++ A+++I
Sbjct: 166 VVVSGTPIRRPMGQMRPDNSKPPVYGASKRLDMELEMAFFVGPGNRFGEPIPISKAQEHI 225
Query: 366 FGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPIAALKPFLLDYNPSHDHEDL 545
FG+VLMNDWSARDIQ+WEYVPLGPFLGKSFGTTISPWVVP+ AL PF++ NP D + L
Sbjct: 226 FGMVLMNDWSARDIQQWEYVPLGPFLGKSFGTTISPWVVPMDALMPFVVP-NPKQDPKPL 284
Query: 546 DYLKDDKSFTFDINLEVFIKPKDFXXXXXXXXXXXXYLYWTMKQQLVHHTVNGCNIQPGD 725
YL + +TFDINL V +K + ++YWT+ QQL HH+VNGCN++PGD
Sbjct: 285 PYLCHSQPYTFDINLSVALKGEGMSQAATICRSNFKHMYWTILQQLTHHSVNGCNLRPGD 344
Query: 726 L 728
L
Sbjct: 345 L 345
>sp|Q00770|FAAA_EMENI Fumarylacetoacetase (Fumarylacetoacetate hydrolase)
(Beta-diketonase) (FAA)
Length = 431
Score = 248 bits (633), Expect = 1e-65
Identities = 128/246 (52%), Positives = 162/246 (65%), Gaps = 5/246 (2%)
Frame = +3
Query: 6 AFVSMNTAKMHVPAEIGDYTDFYSSKDHAVNVGIMFRGKENALMPNWTWLPVGYHGRSSS 185
A + ++ H+P +IGDYTDFY+ +HA NVG++FRG +NAL PN+ LPV YHGR+SS
Sbjct: 113 ALLPLSEVTNHLPMQIGDYTDFYAGLNHAYNVGVLFRGPDNALQPNYKHLPVAYHGRASS 172
Query: 186 IVVSGTPIHRPCGQ--TKPDDADK-PTYGPCKMLDFELEMAFFTGPGNKLGQPITMNNAE 356
+V SGTP+HRP GQ T P K PT+ PCK LD ELE+AFF N LG P+ ++ AE
Sbjct: 173 VVTSGTPLHRPQGQILTNPAANPKLPTFSPCKKLDIELELAFFVSTPNDLGHPVHIDKAE 232
Query: 357 KNIFGVVLMNDWSARDIQKWEYVPLGPFLGKSFGTTISPWVVPIAALKPF-LLDYNPSHD 533
+IFGVVLMNDWSARDIQ WEYVPLGPF K+FGTTI+PWVV I AL+PF + P +
Sbjct: 233 DHIFGVVLMNDWSARDIQAWEYVPLGPFNAKNFGTTITPWVVLIDALEPFRTVGLEPGNR 292
Query: 534 HEDLDYLKDDKSFT-FDINLEVFIKPKDFXXXXXXXXXXXXYLYWTMKQQLVHHTVNGCN 710
L YL++ ++ T +DI LEV + LY + Q L HHT+ GCN
Sbjct: 293 ESLLPYLREKRADTAYDIPLEVEVTNAGGEPTVISRSNAKNLLY-SFPQMLAHHTITGCN 351
Query: 711 IQPGDL 728
+ GDL
Sbjct: 352 LNTGDL 357
>sp|Q8K4G1|LTBP4_MOUSE Latent transforming growth factor beta binding protein 4 precursor
(LTBP-4)
Length = 1666
Score = 32.3 bits (72), Expect = 1.3
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 3/45 (6%)
Frame = -1
Query: 319 FPGPVKKAISSSKSNILQGPYVGLSASSGFV---CPHGR*IGVPD 194
FP P + + S + L PY GL A + CPHGR + VP+
Sbjct: 1551 FPEPEESSERGSYTGALSEPYEGLEAEECGILDGCPHGRCVRVPE 1595
>sp|Q59050|YG56_METJA Hypothetical protein MJ1656
Length = 237
Score = 32.3 bits (72), Expect = 1.3
Identities = 22/71 (30%), Positives = 36/71 (50%), Gaps = 11/71 (15%)
Frame = +3
Query: 270 KMLDFELEMAFFTGPGNKLGQPITMNNAEKNIFGVVLMNDWSARDIQ----KW------- 416
K +D+E+E+A G K + I + A I G ++ND +ARD+Q +W
Sbjct: 86 KRVDYEVELAIVIG---KKCKNIKKDEANDYIMGYTILNDVTARDLQQKDGQWTRAKSFD 142
Query: 417 EYVPLGPFLGK 449
+ P+GP + K
Sbjct: 143 TFCPIGPRIVK 153
>sp|Q8J0Q0|MNS1_CANAL Mannosyl-oligosaccharide 1,2-alpha-mannosidase
(Man(9)-alpha-mannosidase)
Length = 565
Score = 30.4 bits (67), Expect = 5.0
Identities = 17/76 (22%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Frame = +3
Query: 378 LMNDWSARDIQKWEYVPLGPFL--GKSFGTTISPWVVPIAALKPFLLDYNPSHDHEDLDY 551
+++ W + W Y P G++ G W++ + +L ++ P D+
Sbjct: 46 ILDSWHTYEKYGWGYDVYHPIKQEGENMGPKPLGWMI-VDSLDTLMIMDCPEEVSRARDW 104
Query: 552 LKDDKSFTFDINLEVF 599
+K+D +TFD N+ F
Sbjct: 105 IKNDLDYTFDYNVNTF 120
>sp|Q83DV5|GLPE_COXBU Thiosulfate sulfurtransferase glpE
Length = 107
Score = 30.0 bits (66), Expect = 6.6
Identities = 11/29 (37%), Positives = 20/29 (68%)
Frame = -2
Query: 456 QNFSPEMDQEEHIPIFEYHGLTSHSSEQH 370
Q +S + D+E+ + ++ YHG++S S QH
Sbjct: 48 QEYSEKADKEKPVLVYCYHGISSQSVAQH 76
>sp|Q9ZLL2|MURC_HELPJ UDP-N-acetylmuramate--L-alanine ligase
(UDP-N-acetylmuramoyl-L-alanine synthetase)
Length = 449
Score = 30.0 bits (66), Expect = 6.6
Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 8/102 (7%)
Frame = -2
Query: 552 NNLNLHDHEKDYNPTEMVLTQL*VQPMEK*LYQNFSPEMDQEEHIPIFEYHGLTS--HSS 379
NNL L D + ++PTE+ T + +Y N QE+ I I++ H + +
Sbjct: 312 NNLILID-DYAHHPTEIGATLKSAR-----IYANLLNT--QEKIIVIWQAHKYSRLMDNL 363
Query: 378 EQHRKCFFPHCSSLLVDLTYFLVQ*KRP------FRVQSPTF 271
E+ +KCF HC L++ Y + KR F+ +PTF
Sbjct: 364 EEFKKCFLEHCDRLIILPVYSASEVKRDIDLKAHFKHYNPTF 405
>sp|Q8DD17|NUDC_VIBVU NADH pyrophosphatase
Length = 261
Score = 29.6 bits (65), Expect = 8.6
Identities = 14/37 (37%), Positives = 17/37 (45%)
Frame = +3
Query: 471 PWVVPIAALKPFLLDYNPSHDHEDLDYLKDDKSFTFD 581
PW P + + FL DY+ D L D K FT D
Sbjct: 198 PWAFPSSMMMAFLADYHAGELKPDYSELADAKWFTSD 234
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,800,021
Number of Sequences: 369166
Number of extensions: 2081970
Number of successful extensions: 4873
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4685
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4867
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6486082400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)