DrC_00319
- Cluster detail
- GO Category :
- Consensus Sequence :
BLASTX 2.2.13 [Nov-27-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00319 (1076 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q8BMA6|SRP68_MOUSE Signal recognition particle 68 kDa pr... 131 3e-30 sp|Q9UHB9|SRP68_HUMAN Signal recognition particle 68 kDa pr... 130 5e-30 sp|Q00004|SRP68_CANFA Signal recognition particle 68 kDa pr... 128 3e-29 sp|Q9VSS2|SRP68_DROME Probable signal recognition particle ... 122 2e-27 sp|Q20822|SRP68_CAEEL Probable signal recognition particle ... 122 2e-27 sp|P38687|SRP68_YEAST Signal recognition particle 68 kDa pr... 42 0.004 sp|Q6IDD9|SARM1_DROME Sterile alpha and TIR motif containin... 33 1.1 sp|P25446|TNR6_MOUSE Tumor necrosis factor receptor superfa... 33 1.4 sp|P36621|CAP_SCHPO Adenylyl cyclase-associated protein (CAP) 33 1.4 sp|Q9EZE7|ESPC_ECO27 Serine protease espC precursor (EPEC-s... 33 1.4
>sp|Q8BMA6|SRP68_MOUSE Signal recognition particle 68 kDa protein (SRP68) Length = 625 Score = 131 bits (330), Expect = 3e-30 Identities = 101/307 (32%), Positives = 157/307 (51%), Gaps = 13/307 (4%) Frame = +3 Query: 3 SVRDDLKNSSMPNNPAQITNLNLET--MSRLQILFVYLHYVKLTKTVERN---------- 146 +VR++LK P+ + L+ E+ +S LQ L YL Y+KL+ + RN Sbjct: 349 AVREELK----PDQKQRDYALDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLHRA 404 Query: 147 LLIIENNMDTSAS-KPQNMARLYDTVMQNLQEMAGLSGLNRESNDNNAQQEIQAKISAYT 323 LL + D+ S +PQ++ RLYD ++QNL E+ L GL D Q+EI K + Sbjct: 405 LLQQQPEDDSKRSPRPQDLIRLYDIILQNLVELLQLPGLEE---DRTFQKEISLKTLVFK 461 Query: 324 AYRCYYLSQAHLLMKRFAECTALLTRTLRHCENALSNLKLIGNTESESGVSVTKRLIPGP 503 AYRC++++Q+++L+K+++E L R L++ N S G + L P Sbjct: 462 AYRCFFIAQSYVLVKKWSEALVLYDRVLKYA-----------NEVSSHGGASKNSLKDLP 510 Query: 504 SVKEMMEKINSLIESISADQLICRADRCLSMIDDASIENCPASENIELPLAKRLDEFVED 683 V+E++ ++ S S+ A ++ D S D S + +N PL +R + F D Sbjct: 511 DVQELITQVRSEKCSLQAAAILDAND---SHQTDTSYQ---VKDNT--PLVERFESFCLD 562 Query: 684 PYLSKKTSSQSTGRLIQTCPEFEPIPVKPVFFDLAFYHVKFPSLEDKIKDRRGRAADSKG 863 P L K ++ L+ P F+PIP KP+FFDLA HV FP LEDK++ + G Sbjct: 563 PSLVTKQAN-----LVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQK-----TKSG 612 Query: 864 LTGMVKG 884 LTG +KG Sbjct: 613 LTGYIKG 619
>sp|Q9UHB9|SRP68_HUMAN Signal recognition particle 68 kDa protein (SRP68) Length = 627 Score = 130 bits (328), Expect = 5e-30 Identities = 89/280 (31%), Positives = 140/280 (50%), Gaps = 11/280 (3%) Frame = +3 Query: 78 MSRLQILFVYLHYVKLTKTVERN----------LLIIENNMDTSAS-KPQNMARLYDTVM 224 +S LQ L YL Y+KL+ ++RN LL + D+ S +PQ++ RLYD ++ Sbjct: 373 VSNLQYLHSYLTYIKLSTAIKRNENMAKGLQRALLQQQPEDDSKRSPRPQDLIRLYDIIL 432 Query: 225 QNLQEMAGLSGLNRESNDNNAQQEIQAKISAYTAYRCYYLSQAHLLMKRFAECTALLTRT 404 QNL E+ L GL D Q+EI K + AYRC++++Q+++L+K+++E L R Sbjct: 433 QNLVELLQLPGLEE---DKAFQKEIGLKTLVFKAYRCFFIAQSYVLVKKWSEALVLYDRV 489 Query: 405 LRHCENALSNLKLIGNTESESGVSVTKRLIPGPSVKEMMEKINSLIESISADQLICRADR 584 L++ S+ N S+K++ + + LI + +++ +A Sbjct: 490 LKYANEVNSDAGAFKN-----------------SLKDLPD-VQELITQVRSEKCSLQAAA 531 Query: 585 CLSMIDDASIENCPASENIELPLAKRLDEFVEDPYLSKKTSSQSTGRLIQTCPEFEPIPV 764 L D E + PL +R + F DP L K ++ L+ P F+PIP Sbjct: 532 ILDANDAHQTETSSSQVKDNKPLVERFETFCLDPSLVTKQAN-----LVHFPPGFQPIPC 586 Query: 765 KPVFFDLAFYHVKFPSLEDKIKDRRGRAADSKGLTGMVKG 884 KP+FFDLA HV FP LEDK++ + GLTG +KG Sbjct: 587 KPLFFDLALNHVAFPPLEDKLEQK-----TKSGLTGYIKG 621
>sp|Q00004|SRP68_CANFA Signal recognition particle 68 kDa protein (SRP68) Length = 622 Score = 128 bits (321), Expect = 3e-29 Identities = 94/309 (30%), Positives = 155/309 (50%), Gaps = 15/309 (4%) Frame = +3 Query: 3 SVRDDLKNSSMPNNPAQITNLNLET--MSRLQILFVYLHYVKLTKTVERNLLIIEN---- 164 +VR++LK P+ + L+ E+ +S LQ L YL Y+KL+ + RN + + Sbjct: 347 AVREELK----PDQKQRDYTLDGESGKVSNLQYLHSYLTYIKLSTAIRRNENMAKGLQKA 402 Query: 165 ------NMDTSASKPQNMARLYDTVMQNLQEMAGLSGLNRESNDNNAQQEIQAKISAYTA 326 + + +PQ++ RLYD ++QNL E+ L GL D Q+EI K + A Sbjct: 403 LQQQPEDESKRSPRPQDLIRLYDIILQNLVELLQLPGLEE---DRAFQKEIGLKTLVFKA 459 Query: 327 YRCYYLSQAHLLMKRFAECTALLTRTLRHCENALSNLKLIGNTESESGVSVTKRLIPGPS 506 YRC++++Q+++L+K+++E L R L++ S+ N+ + P Sbjct: 460 YRCFFIAQSYVLVKKWSEALVLYDRVLKYANEVNSDAGAFRNSLKDL-----------PD 508 Query: 507 VKEMMEKINSLIESISADQLICRADRCLSMIDDASIENCPASENI---ELPLAKRLDEFV 677 V+E++ ++ S S+ A ++ DAS + P + + PL +R + F Sbjct: 509 VQELITQVRSEKCSLQAAAIL-----------DASDSHQPETSSQVKDNKPLVERFETFC 557 Query: 678 EDPYLSKKTSSQSTGRLIQTCPEFEPIPVKPVFFDLAFYHVKFPSLEDKIKDRRGRAADS 857 DP L K ++ L+ P F+PIP KP+FFDLA HV FP LEDK++ + Sbjct: 558 LDPSLVTKQAN-----LVHFPPGFQPIPCKPLFFDLALNHVAFPPLEDKLEQK-----TK 607 Query: 858 KGLTGMVKG 884 GLTG +KG Sbjct: 608 SGLTGYIKG 616
>sp|Q9VSS2|SRP68_DROME Probable signal recognition particle 68 kDa protein (SRP68) Length = 604 Score = 122 bits (306), Expect = 2e-27 Identities = 91/316 (28%), Positives = 154/316 (48%), Gaps = 18/316 (5%) Frame = +3 Query: 3 SVRDDLKNSSMPNNPAQITNLNLETMSRLQILFVYLHYVKLTKTVERNLLIIE------- 161 +VRD++K +P + +T+S +Q L YL Y++ ++T++RNL ++E Sbjct: 322 AVRDEIKQ-----DPKLRSLTTGQTVSGVQYLLAYLSYIRHSRTLQRNLCLVEQAKLNFY 376 Query: 162 --------NNMDTSASKPQNMARLYDTVMQNLQEMAGLSGLNRESNDNNAQQEIQAKISA 317 N D +PQ++ARLY+ ++QN+ EM ++GL +D Q E++ Sbjct: 377 DPNLQSQQNVGDGKRVRPQDLARLYEIILQNVTEMQQINGLE---DDATYQSEVENLAIT 433 Query: 318 YTAYRCYYLSQAHLLMKRFAECTALLTRTLRHCENALSNLKLIGNTESESGVSVTKRLIP 497 + A+RCYY++ + +K++ E AL R + AL G + E Sbjct: 434 FKAFRCYYIALTLIDIKKWKEAVALYERASNYATEALK-----GKSSPEF---------- 478 Query: 498 GPSVKEMMEKINSLIESISADQLICRADRCLSMIDDASIEN--CPASENIELPLAKRLDE 671 ++ E++ ++ +I + A L DD S E+ S+ PL +RL Sbjct: 479 -----QLQEELKKVVSAIDGCKFSAHAYSVLE--DDNSEESGTTTKSQKTTKPLYERLSL 531 Query: 672 FVEDPYLSKKTSSQSTGRLIQTCPEFEPIPVKPVFFDLAFYHVKFPSLEDKIKDRRGRAA 851 + ED L K + + + P+ EPIP KP+FFDLA +V+ PSLE K++ + A Sbjct: 532 YKEDQSLHTKAPN-----VFKLTPDMEPIPCKPIFFDLAMTYVELPSLEGKLESPGKKGA 586 Query: 852 DSKGLTGMVKGWI-WG 896 +TG VKG++ WG Sbjct: 587 ---SITGFVKGFLGWG 599
>sp|Q20822|SRP68_CAEEL Probable signal recognition particle 68 kDa protein (SRP68) Length = 622 Score = 122 bits (305), Expect = 2e-27 Identities = 86/302 (28%), Positives = 148/302 (49%), Gaps = 32/302 (10%) Frame = +3 Query: 87 LQILFVYLHYVKLTKTVERNLLIIENNMDTSASKPQNMARLYDTVMQNLQEMAGLSGLNR 266 LQ + YL ++K+ T R L II+N SKPQ++ RLYD+V++ +E+A + G + Sbjct: 341 LQSIKAYLEFLKMNGTASRYLAIIDNTKSEKKSKPQDLLRLYDSVIEIYKEVAEIPGAD- 399 Query: 267 ESNDNNAQQEIQAKISAYTAYRCYYLSQAHLLMKRFAECTALLTRTLRHCENALSNLKLI 446 +D N Q + K+ Y A+RC+Y++ ++ + +++E AL RT+ ++A LK + Sbjct: 400 --HDKNLIQAFEVKVEYYRAFRCFYMASSYSALHKYSEAAALFDRTVSRVQDAEGKLKKL 457 Query: 447 GNTESESGVSVTKRLIPGPSVKEMMEKINSLIESISADQLICRADRCLSMIDDASIENCP 626 +S S ++ E +N L + + ++ RA R S D ++ Sbjct: 458 ---KSSSFIT-----------NETQSSLNELRSEVESAKVTVRAARLASAAGDVKTDSEL 503 Query: 627 ASENIELPLAKRLDEF----VEDPYLSKKTSSQSTGRLIQTCPEFEPIPVKPVFFDLAFY 794 A + PL + ++E+ V + KKT + P F P+P KP+FFDLA + Sbjct: 504 AKIIDKRPLLETVNEWRQWDVRNSLKDKKTIP-----VASLPPAFIPMPNKPIFFDLANF 558 Query: 795 HVKFPSLEDKI----KDR--------RGRAA-------------DSKGLTGMVKGW---I 890 H+ P+++D++ KDR +G +A + +GLTGM+ GW Sbjct: 559 HLTMPNVDDRLEKLQKDRDATPKKAAKGSSAAAASSKTSNQEEEEQQGLTGMLSGWKKSF 618 Query: 891 WG 896 WG Sbjct: 619 WG 620
>sp|P38687|SRP68_YEAST Signal recognition particle 68 kDa protein homolog (SRP68) Length = 599 Score = 41.6 bits (96), Expect = 0.004 Identities = 59/292 (20%), Positives = 115/292 (39%), Gaps = 6/292 (2%) Frame = +3 Query: 12 DDLKNSSMPNNPAQIT----NLNLETMSRLQILFVYLHYVKLTKTVERNLLIIENNMDTS 179 D++ +S NN + N+ L ++SR + LF +L L + ++ + Sbjct: 320 DEMVENSSENNQIILAYIKYNILLTSISRERDLFTHLW---------NQWLKLNTSLPSK 370 Query: 180 ASKPQNMARLYDTVMQNLQEMAGLSGLNRESNDNNAQQEIQAKISAYTAYRCYYLSQAHL 359 +K + M R+ + + L ++ L G+ S+D Q K+ LS + Sbjct: 371 LTKYKEMERIVKNLTKYLSDIMELPGVY--SDDELLSQLDLCKLYFQLFLNTGCLSVLYQ 428 Query: 360 LMKRFAECTALLTRTLRHCENALSNLKLIGNTESESGVSVTKRLIPGPSVKEMMEKINSL 539 R+ E AL R EN LS + ES + + L+ SV+ + ++I + Sbjct: 429 SKGRYMEALALYVDAYRRLENKLSEI------ESLDEILLPANLLSLNSVRSLQKRIENG 482 Query: 540 IESISADQLICRADRCLSMIDDASIENCPASENIELPLAKRLDEFVEDPYLSKKT--SSQ 713 S+ +++ + + + +L + ++LD SKK + Sbjct: 483 GNSV------------ITLAEYEKRNHGGSLGKYDLTVIEKLD--------SKKILPTDI 522 Query: 714 STGRLIQTCPEFEPIPVKPVFFDLAFYHVKFPSLEDKIKDRRGRAADSKGLT 869 L P+ PIP KP FDLAF ++ + E + +++ ++ Sbjct: 523 QLKNLFPLKPKMLPIPSKPTLFDLAFNYITYDKQEPSASQVKDSVTETESIS 574
>sp|Q6IDD9|SARM1_DROME Sterile alpha and TIR motif containing protein 1 (Tir-1 homolog) Length = 1360 Score = 33.5 bits (75), Expect = 1.1 Identities = 15/36 (41%), Positives = 21/36 (58%) Frame = +3 Query: 378 ECTALLTRTLRHCENALSNLKLIGNTESESGVSVTK 485 EC TLRHC +AL+NL L G E++ + + K Sbjct: 497 ECRTSDLETLRHCASALANLSLYGGAENQEEMILRK 532
>sp|P25446|TNR6_MOUSE Tumor necrosis factor receptor superfamily member 6 precursor (FASL receptor) (Apoptosis-mediating surface antigen FAS) (Apo-1 antigen) (CD95 antigen) Length = 327 Score = 33.1 bits (74), Expect = 1.4 Identities = 17/43 (39%), Positives = 23/43 (53%), Gaps = 1/43 (2%) Frame = -3 Query: 324 QCTLRFSLESPA-EHCYRCSHDSIRTIPPFPASSASRCRTISP 199 +C F +SP EHC RC+ T+ P A+S + CR SP Sbjct: 124 KCKPDFYCDSPGCEHCVRCASCEHGTLEPCTATSNTNCRKQSP 166
>sp|P36621|CAP_SCHPO Adenylyl cyclase-associated protein (CAP) Length = 551 Score = 33.1 bits (74), Expect = 1.4 Identities = 27/107 (25%), Positives = 47/107 (43%) Frame = +3 Query: 234 QEMAGLSGLNRESNDNNAQQEIQAKISAYTAYRCYYLSQAHLLMKRFAECTALLTRTLRH 413 Q A +S NR +A + + A ISAY + YLS+ L K+ L+ H Sbjct: 81 QVAAAISPRNRSLTSTSAVEAVPASISAYDEFCSKYLSKYMELSKKIG---GLIAEQSEH 137 Query: 414 CENALSNLKLIGNTESESGVSVTKRLIPGPSVKEMMEKINSLIESIS 554 E A + L+ + + + K + P + E ++ I S + +I+ Sbjct: 138 VEKAFNLLRQVLSV----ALKAQKPDMDSPELLEFLKPIQSELLTIT 180
>sp|Q9EZE7|ESPC_ECO27 Serine protease espC precursor (EPEC-secreted protein C) Length = 1305 Score = 33.1 bits (74), Expect = 1.4 Identities = 23/73 (31%), Positives = 33/73 (45%) Frame = -2 Query: 718 VDCEDVFFDRYGSSTNSSNRLASGNSIFSDAGQFSIDASSIIDKQRSARQINWSALMLSM 539 V ++ FDR GS NSS L G + + G FS A +D + +A I Sbjct: 732 VTSQNAVFDRVGSFVNSSLTLEKGAKLTAQGGIFSTGA---VDVKENASLILTGTPSAQK 788 Query: 538 RELIFSIISLTDG 500 +E +IS T+G Sbjct: 789 QEYYSPVISTTEG 801
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 123,732,432
Number of Sequences: 369166
Number of extensions: 2526550
Number of successful extensions: 8563
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 8031
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8543
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11725506360
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
Cluster detail
