Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00317 (922 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P31319|KAPR_APLCA cAMP-dependent protein kinase regulato... 330 4e-90 sp|Q9DBC7|KAP0_MOUSE cAMP-dependent protein kinase type I-a... 324 2e-88 sp|P00514|KAP0_BOVIN cAMP-dependent protein kinase type I-a... 324 2e-88 sp|P12849|KAP1_MOUSE cAMP-dependent protein kinase type I-b... 323 5e-88 sp|P07802|KAP0_PIG cAMP-dependent protein kinase type I-alp... 322 7e-88 sp|P81377|KAP1_RAT cAMP-dependent protein kinase type I-bet... 322 9e-88 sp|P31321|KAP1_HUMAN cAMP-dependent protein kinase type I-b... 322 1e-87 sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-a... 320 3e-87 sp|P09456|KAP0_RAT cAMP-dependent protein kinase type I-alp... 317 3e-86 sp|P16905|KAPR1_DROME cAMP-dependent protein kinase type I ... 311 1e-84
>sp|P31319|KAPR_APLCA cAMP-dependent protein kinase regulatory subunit (N4 subunit of protein kinase A) Length = 378 Score = 330 bits (845), Expect = 4e-90 Identities = 175/291 (60%), Positives = 216/291 (74%), Gaps = 1/291 (0%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEK-QLQKDXXXXXXXXX 227 ++E E Y++KHNI QLLK+C+V+L ++KP SP++F+R++F LEK Q+ K+ Sbjct: 11 LKECEAYVQKHNIQQLLKECIVQLVVNKPESPLAFLRDHFDRLEKEQVAKEK-------- 62 Query: 228 XXXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGA 407 S S +E E+ M+ + A +K R+RRGA Sbjct: 63 ------------SKSATPPSDEKEEDMSSTP------------PQMHPAMNK--RMRRGA 96 Query: 408 VSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKK 587 VS EVY E+DAA YVKKVVPKDYKTM+ALSKAI KNVLFSHLD+ ERSDIFDAMFP+H+ Sbjct: 97 VSAEVYREEDAAQYVKKVVPKDYKTMAALSKAISKNVLFSHLDDNERSDIFDAMFPVHRH 156 Query: 588 AYETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKAST 767 A E IIQQGD+GDNFY+IDQGEV++YVN+ ++ EGGSFGELALIYGTPRAATVKA T Sbjct: 157 AGEVIIQQGDEGDNFYVIDQGEVDVYVNNVHVTSIGEGGSFGELALIYGTPRAATVKAKT 216 Query: 768 DVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 DVKLWGIDRDSYRRILMGSTI+KRK+Y++FLS+V ILE+LDKWE+LTVADA Sbjct: 217 DVKLWGIDRDSYRRILMGSTIRKRKIYEDFLSKVSILENLDKWERLTVADA 267
Score = 63.9 bits (154), Expect = 6e-10 Identities = 47/152 (30%), Positives = 75/152 (49%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + K + +LD+ ER + DA+ P+ + E I++QG Sbjct: 224 DRDSYRRILMGSTIRKRKIYEDFLSKVSILENLDKWERLTVADALEPVQFEDKEEIVRQG 283 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + G++F+II +G + N E G FGE+AL+ PRAATV A +K Sbjct: 284 EPGEDFFIILEGSAAVLQRRSENEEPVEVGRLGPSDYFGEIALLLDRPRAATVVARGPLK 343 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 344 CVKLDRARFERVLGPCSDILKRNISQYNSFVS 375
>sp|Q9DBC7|KAP0_MOUSE cAMP-dependent protein kinase type I-alpha regulatory subunit Length = 381 Score = 324 bits (831), Expect = 2e-88 Identities = 170/290 (58%), Positives = 210/290 (72%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230 + E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ + Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQIQ-------- 66 Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410 C + ED ++ + VV K R RRGA+ Sbjct: 67 ----------CLQKTGIRTDSREDEISP----------PPPNPVV------KGRRRRGAI 100 Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590 S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 160 Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770 ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+ Sbjct: 161 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220 Query: 771 VKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADA Sbjct: 221 VKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADA 270
Score = 63.2 bits (152), Expect = 1e-09 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD F+II +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 378
>sp|P00514|KAP0_BOVIN cAMP-dependent protein kinase type I-alpha regulatory subunit Length = 379 Score = 324 bits (831), Expect = 2e-88 Identities = 169/290 (58%), Positives = 207/290 (71%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230 + E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K Sbjct: 13 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAG-- 70 Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410 S DS + ++ K R RRGA+ Sbjct: 71 -------------SRADSREDEISPPPPNPVV-------------------KGRRRRGAI 98 Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590 S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A Sbjct: 99 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 158 Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770 ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+ Sbjct: 159 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 218 Query: 771 VKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADA Sbjct: 219 VKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADA 268
Score = 63.5 bits (153), Expect = 8e-10 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG Sbjct: 225 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 284 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD F+II +G + N E G FGE+AL+ PRAATV A +K Sbjct: 285 EPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 344 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 345 CVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 376
>sp|P12849|KAP1_MOUSE cAMP-dependent protein kinase type I-beta regulatory subunit Length = 381 Score = 323 bits (827), Expect = 5e-88 Identities = 166/286 (58%), Positives = 205/286 (71%) Frame = +3 Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242 E Y++KH I Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ + Sbjct: 19 EMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQI------------- 65 Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422 + S ++ + H DE S KAR RRG VS EV Sbjct: 66 --------LARQKSNSQCDSH-------------DEEISPTPPNPVVKARRRRGGVSAEV 104 Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602 YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ ET+ Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETV 164 Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782 IQQG++GDNFY+IDQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW Sbjct: 165 IQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224 Query: 783 GIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 GIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADA Sbjct: 225 GIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADA 270
Score = 66.6 bits (161), Expect = 9e-11 Identities = 48/152 (31%), Positives = 74/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + L++ ER + DA+ P+ + E I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD+FYII +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSEILKRNIQRYNSFIS 378
>sp|P07802|KAP0_PIG cAMP-dependent protein kinase type I-alpha regulatory subunit Length = 380 Score = 322 bits (826), Expect = 7e-88 Identities = 169/290 (58%), Positives = 209/290 (72%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230 + E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K Sbjct: 14 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQ---------- 63 Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410 + L+ A + + + VV K R RRGA+ Sbjct: 64 ------------------IQNLQKASARADSREDEISPPPPNPVV------KGRRRRGAI 99 Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590 S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A Sbjct: 100 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 159 Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770 ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+ Sbjct: 160 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 219 Query: 771 VKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 VKLWG DRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADA Sbjct: 220 VKLWGNDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADA 269
Score = 63.9 bits (154), Expect = 6e-10 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 9/153 (5%) Frame = +3 Query: 432 DDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQ 611 +D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ Q Sbjct: 225 NDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQ 284 Query: 612 GDDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDV 773 G+ GD F+II +G + N E G FGE+AL+ PRAATV A + Sbjct: 285 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 344 Query: 774 KLWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 K +DR + R+L S I KR + Y F+S Sbjct: 345 KCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 377
>sp|P81377|KAP1_RAT cAMP-dependent protein kinase type I-beta regulatory subunit Length = 381 Score = 322 bits (825), Expect = 9e-88 Identities = 166/286 (58%), Positives = 205/286 (71%) Frame = +3 Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242 E Y++KH I Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ + Sbjct: 19 EMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQI------------- 65 Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422 + S ++ + H DE S KAR RRG VS EV Sbjct: 66 --------LARQKSNSQCDSH-------------DEEISPTPPNPVVKARRRRGGVSAEV 104 Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602 YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ ET+ Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIDGETV 164 Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782 IQQG++GDNFY+IDQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW Sbjct: 165 IQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224 Query: 783 GIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 GIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVADA Sbjct: 225 GIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADA 270
Score = 66.6 bits (161), Expect = 9e-11 Identities = 48/152 (31%), Positives = 74/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + L++ ER + DA+ P+ + E I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD+FYII +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSEILKRNIQRYNSFIS 378
>sp|P31321|KAP1_HUMAN cAMP-dependent protein kinase type I-beta regulatory subunit Length = 381 Score = 322 bits (824), Expect = 1e-87 Identities = 165/285 (57%), Positives = 204/285 (71%) Frame = +3 Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242 E Y++ H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ + Sbjct: 19 ELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQI------------- 65 Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422 + S ++ + H DE S KAR RRG VS EV Sbjct: 66 --------LARQKSNSQSDSH-------------DEEVSPTPPNPVVKARRRRGGVSAEV 104 Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602 YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A ET+ Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETV 164 Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782 IQQG++GDNFY++DQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW Sbjct: 165 IQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224 Query: 783 GIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVAD 917 GIDRDSYRRILMGST++KRK+Y+EFLS+V ILE L+KWE+LTVAD Sbjct: 225 GIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVAD 269
Score = 64.7 bits (156), Expect = 3e-10 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + L++ ER + D + P+ + E I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADRLEPVQFEDGEKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD+FYII +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSEILKRNIQRYNSFIS 378
>sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1) Length = 381 Score = 320 bits (821), Expect = 3e-87 Identities = 167/290 (57%), Positives = 205/290 (70%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230 + E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAG-- 72 Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410 + DS + ++ K R RRGA+ Sbjct: 73 -------------TRTDSREDEISPPPPNPVV-------------------KGRRRRGAI 100 Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590 S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMF + A Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA 160 Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770 ET+IQQGD+GDNFY+IDQGE ++YVN+E +V EGGSFGELALIYGTPRAATVKA T+ Sbjct: 161 GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220 Query: 771 VKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADA Sbjct: 221 VKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADA 270
Score = 63.5 bits (153), Expect = 8e-10 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD F+II +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 378
>sp|P09456|KAP0_RAT cAMP-dependent protein kinase type I-alpha regulatory subunit Length = 381 Score = 317 bits (812), Expect = 3e-86 Identities = 167/290 (57%), Positives = 207/290 (71%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230 + E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ +L+K+ Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFE----RLEKEEARQIQSLQK 70 Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410 S DS + ++ K R RRGA+ Sbjct: 71 -----------SGIRTDSREDEISPPPPNPVV-------------------KGRRRRGAI 100 Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590 S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 160 Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770 ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+ Sbjct: 161 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220 Query: 771 VKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 VKLWGIDRDSYRRILMGST++KRK+Y+EFLS+V ILE LDKWE+LTVADA Sbjct: 221 VKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADA 270
Score = 63.2 bits (152), Expect = 1e-09 Identities = 47/152 (30%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 + GD F+II +G + N E G FGE+AL+ PRAATV A +K Sbjct: 287 EPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L S I KR + Y F+S Sbjct: 347 CVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 378
>sp|P16905|KAPR1_DROME cAMP-dependent protein kinase type I regulatory subunit (DRI class I to class IV) Length = 376 Score = 311 bits (798), Expect = 1e-84 Identities = 166/291 (57%), Positives = 206/291 (70%), Gaps = 1/291 (0%) Frame = +3 Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEK-QLQKDXXXXXXXXX 227 + E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE+ Q++ D Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVKLD--------- 64 Query: 228 XXXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGA 407 A ++I + ++ S + +A R RG Sbjct: 65 ---------------------------ASRQVIS-PDDCEDLSPMPQTAAPPVRR--RGG 94 Query: 408 VSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKK 587 +S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++ Sbjct: 95 ISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHI 154 Query: 588 AYETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKAST 767 A E IIQQGD+GDNFY+ID GEV+++VN EL +SEGGSFGELALIYGTPRAATV+A T Sbjct: 155 AGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKT 214 Query: 768 DVKLWGIDRDSYRRILMGSTIKKRKLYQEFLSRVPILEDLDKWEQLTVADA 920 DVKLWGIDRDSYRRILMGSTI+KRK+Y+EFLSRV ILE LDKWE+LTVAD+ Sbjct: 215 DVKLWGIDRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADS 265
Score = 55.8 bits (133), Expect = 2e-07 Identities = 45/152 (29%), Positives = 73/152 (48%), Gaps = 9/152 (5%) Frame = +3 Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614 D SY + ++ + + + + + LD+ ER + D++ ETI++QG Sbjct: 222 DRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQG 281 Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776 GD+FYII +G + + +E G FGE+AL+ PRAATV A +K Sbjct: 282 AAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLK 341 Query: 777 LWGIDRDSYRRIL-MGSTIKKRKL--YQEFLS 863 +DR + R+L + I KR + Y F+S Sbjct: 342 CVKLDRARFERVLGPCADILKRNITQYNSFVS 373
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,187,777 Number of Sequences: 369166 Number of extensions: 1732577 Number of successful extensions: 5246 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4915 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5142 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9414689480 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)