Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_H08
(807 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31319|KAPR_APLCA cAMP-dependent protein kinase regulato... 268 1e-71
sp|P31321|KAP1_HUMAN cAMP-dependent protein kinase type I-b... 263 3e-70
sp|Q9DBC7|KAP0_MOUSE cAMP-dependent protein kinase type I-a... 263 4e-70
sp|P00514|KAP0_BOVIN cAMP-dependent protein kinase type I-a... 263 4e-70
sp|P12849|KAP1_MOUSE cAMP-dependent protein kinase type I-b... 263 4e-70
sp|P81377|KAP1_RAT cAMP-dependent protein kinase type I-bet... 262 7e-70
sp|P07802|KAP0_PIG cAMP-dependent protein kinase type I-alp... 261 2e-69
sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-a... 259 6e-69
sp|P09456|KAP0_RAT cAMP-dependent protein kinase type I-alp... 256 7e-68
sp|P16905|KAPR1_DROME cAMP-dependent protein kinase type I ... 249 5e-66
>sp|P31319|KAPR_APLCA cAMP-dependent protein kinase regulatory subunit (N4 subunit of
protein kinase A)
Length = 378
Score = 268 bits (686), Expect = 1e-71
Identities = 145/253 (57%), Positives = 179/253 (70%), Gaps = 1/253 (0%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEK-QLQKDXXXXXXXXX 227
++E E Y++KHNI QLLK+C+V+L ++KP SP++F+R++F LEK Q+ K+
Sbjct: 11 LKECEAYVQKHNIQQLLKECIVQLVVNKPESPLAFLRDHFDRLEKEQVAKEK-------- 62
Query: 228 XXXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGA 407
S S +E E+ M+ + A +K R+RRGA
Sbjct: 63 ------------SKSATPPSDEKEEDMSSTP------------PQMHPAMNK--RMRRGA 96
Query: 408 VSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKK 587
VS EVY E+DAA YVKKVVPKDYKTM+ALSKAI KNVLFSHLD+ ERSDIFDAMFP+H+
Sbjct: 97 VSAEVYREEDAAQYVKKVVPKDYKTMAALSKAISKNVLFSHLDDNERSDIFDAMFPVHRH 156
Query: 588 AYETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKAST 767
A E IIQQGD+GDNFY+IDQGEV++YVN+ ++ EGGSFGELALIYGTPRAATVKA T
Sbjct: 157 AGEVIIQQGDEGDNFYVIDQGEVDVYVNNVHVTSIGEGGSFGELALIYGTPRAATVKAKT 216
Query: 768 DVKLWGIDRDSYR 806
DVKLWGIDRDSYR
Sbjct: 217 DVKLWGIDRDSYR 229
Score = 57.4 bits (137), Expect = 5e-08
Identities = 38/126 (30%), Positives = 62/126 (49%), Gaps = 6/126 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + K + +LD+ ER + DA+ P+ + E I++QG
Sbjct: 224 DRDSYRRILMGSTIRKRKIYEDFLSKVSILENLDKWERLTVADALEPVQFEDKEEIVRQG 283
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ G++F+II +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 284 EPGEDFFIILEGSAAVLQRRSENEEPVEVGRLGPSDYFGEIALLLDRPRAATVVARGPLK 343
Query: 777 LWGIDR 794
+DR
Sbjct: 344 CVKLDR 349
>sp|P31321|KAP1_HUMAN cAMP-dependent protein kinase type I-beta regulatory subunit
Length = 381
Score = 263 bits (673), Expect = 3e-70
Identities = 137/248 (55%), Positives = 169/248 (68%)
Frame = +3
Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242
E Y++ H I Q+LKDC+V LC+SKP P+ F+RE+F+ LEK+ +
Sbjct: 19 ELYVQLHGIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQI------------- 65
Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422
+ S ++ + H DE S KAR RRG VS EV
Sbjct: 66 --------LARQKSNSQSDSH-------------DEEVSPTPPNPVVKARRRRGGVSAEV 104
Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602
YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLF+HLD+ ERSDIFDAMFP+ A ET+
Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETV 164
Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782
IQQG++GDNFY++DQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW
Sbjct: 165 IQQGNEGDNFYVVDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224
Query: 783 GIDRDSYR 806
GIDRDSYR
Sbjct: 225 GIDRDSYR 232
Score = 57.8 bits (138), Expect = 3e-08
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + L++ ER + D + P+ + E I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADRLEPVQFEDGEKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD+FYII +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|Q9DBC7|KAP0_MOUSE cAMP-dependent protein kinase type I-alpha regulatory subunit
Length = 381
Score = 263 bits (672), Expect = 4e-70
Identities = 140/252 (55%), Positives = 174/252 (69%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230
+ E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ +
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQIQ-------- 66
Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410
C + ED ++ + VV K R RRGA+
Sbjct: 67 ----------CLQKTGIRTDSREDEISP----------PPPNPVV------KGRRRRGAI 100
Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590
S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A
Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 160
Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770
ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+
Sbjct: 161 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220
Query: 771 VKLWGIDRDSYR 806
VKLWGIDRDSYR
Sbjct: 221 VKLWGIDRDSYR 232
Score = 56.6 bits (135), Expect = 8e-08
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD F+II +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|P00514|KAP0_BOVIN cAMP-dependent protein kinase type I-alpha regulatory subunit
Length = 379
Score = 263 bits (672), Expect = 4e-70
Identities = 139/252 (55%), Positives = 171/252 (67%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230
+ E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K
Sbjct: 13 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQNLQKAG-- 70
Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410
S DS + ++ K R RRGA+
Sbjct: 71 -------------SRADSREDEISPPPPNPVV-------------------KGRRRRGAI 98
Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590
S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A
Sbjct: 99 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 158
Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770
ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+
Sbjct: 159 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 218
Query: 771 VKLWGIDRDSYR 806
VKLWGIDRDSYR
Sbjct: 219 VKLWGIDRDSYR 230
Score = 57.0 bits (136), Expect = 6e-08
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG
Sbjct: 225 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 284
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD F+II +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 285 EPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 344
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 345 CVKLDRPRF 353
>sp|P12849|KAP1_MOUSE cAMP-dependent protein kinase type I-beta regulatory subunit
Length = 381
Score = 263 bits (672), Expect = 4e-70
Identities = 137/248 (55%), Positives = 169/248 (68%)
Frame = +3
Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242
E Y++KH I Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ +
Sbjct: 19 EMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQI------------- 65
Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422
+ S ++ + H DE S KAR RRG VS EV
Sbjct: 66 --------LARQKSNSQCDSH-------------DEEISPTPPNPVVKARRRRGGVSAEV 104
Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602
YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ ET+
Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIGGETV 164
Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782
IQQG++GDNFY+IDQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW
Sbjct: 165 IQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224
Query: 783 GIDRDSYR 806
GIDRDSYR
Sbjct: 225 GIDRDSYR 232
Score = 59.7 bits (143), Expect = 9e-09
Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + L++ ER + DA+ P+ + E I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD+FYII +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|P81377|KAP1_RAT cAMP-dependent protein kinase type I-beta regulatory subunit
Length = 381
Score = 262 bits (670), Expect = 7e-70
Identities = 137/248 (55%), Positives = 169/248 (68%)
Frame = +3
Query: 63 EEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXXXXXX 242
E Y++KH I Q+LK+C+V LC++KP P+ F+RE+F+ LEK+ +
Sbjct: 19 EMYVQKHGIQQVLKECIVHLCVAKPDRPLRFLREHFEKLEKEENRQI------------- 65
Query: 243 XHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAVSGEV 422
+ S ++ + H DE S KAR RRG VS EV
Sbjct: 66 --------LARQKSNSQCDSH-------------DEEISPTPPNPVVKARRRRGGVSAEV 104
Query: 423 YTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETI 602
YTE+DA SYV+KV+PKDYKTM+AL+KAI KNVLFSHLD+ ERSDIFDAMFP+ ET+
Sbjct: 105 YTEEDAVSYVRKVIPKDYKTMTALAKAISKNVLFSHLDDNERSDIFDAMFPVTHIDGETV 164
Query: 603 IQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTDVKLW 782
IQQG++GDNFY+IDQGEV++YVN E N+SEGGSFGELALIYGTPRAATVKA TD+KLW
Sbjct: 165 IQQGNEGDNFYVIDQGEVDVYVNGEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLW 224
Query: 783 GIDRDSYR 806
GIDRDSYR
Sbjct: 225 GIDRDSYR 232
Score = 59.7 bits (143), Expect = 9e-09
Identities = 39/129 (30%), Positives = 62/129 (48%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + L++ ER + DA+ P+ + E I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD+FYII +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSDYFGEIALLLNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|P07802|KAP0_PIG cAMP-dependent protein kinase type I-alpha regulatory subunit
Length = 380
Score = 261 bits (667), Expect = 2e-69
Identities = 139/252 (55%), Positives = 173/252 (68%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230
+ E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K
Sbjct: 14 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQ---------- 63
Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410
+ L+ A + + + VV K R RRGA+
Sbjct: 64 ------------------IQNLQKASARADSREDEISPPPPNPVV------KGRRRRGAI 99
Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590
S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A
Sbjct: 100 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 159
Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770
ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+
Sbjct: 160 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 219
Query: 771 VKLWGIDRDSYR 806
VKLWG DRDSYR
Sbjct: 220 VKLWGNDRDSYR 231
Score = 57.4 bits (137), Expect = 5e-08
Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 6/130 (4%)
Frame = +3
Query: 432 DDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQ 611
+D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ Q
Sbjct: 225 NDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQ 284
Query: 612 GDDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDV 773
G+ GD F+II +G + N E G FGE+AL+ PRAATV A +
Sbjct: 285 GEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPL 344
Query: 774 KLWGIDRDSY 803
K +DR +
Sbjct: 345 KCVKLDRPRF 354
>sp|P10644|KAP0_HUMAN cAMP-dependent protein kinase type I-alpha regulatory subunit
(Tissue-specific extinguisher 1) (TSE1)
Length = 381
Score = 259 bits (662), Expect = 6e-69
Identities = 137/252 (54%), Positives = 169/252 (67%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230
+ E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ LEK+ K
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQIQNLQKAG-- 72
Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410
+ DS + ++ K R RRGA+
Sbjct: 73 -------------TRTDSREDEISPPPPNPVV-------------------KGRRRRGAI 100
Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590
S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMF + A
Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIA 160
Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770
ET+IQQGD+GDNFY+IDQGE ++YVN+E +V EGGSFGELALIYGTPRAATVKA T+
Sbjct: 161 GETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220
Query: 771 VKLWGIDRDSYR 806
VKLWGIDRDSYR
Sbjct: 221 VKLWGIDRDSYR 232
Score = 57.0 bits (136), Expect = 6e-08
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD F+II +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|P09456|KAP0_RAT cAMP-dependent protein kinase type I-alpha regulatory subunit
Length = 381
Score = 256 bits (653), Expect = 7e-68
Identities = 137/252 (54%), Positives = 171/252 (67%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEKQLQKDXXXXXXXXXX 230
+ E E Y++KHNI LLKD +V+LC ++P P++F+REYF+ +L+K+
Sbjct: 15 LRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFE----RLEKEEARQIQSLQK 70
Query: 231 XXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGAV 410
S DS + ++ K R RRGA+
Sbjct: 71 -----------SGIRTDSREDEISPPPPNPVV-------------------KGRRRRGAI 100
Query: 411 SGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKA 590
S EVYTE+DAASYV+KV+PKDYKTM+AL+KAIEKNVLFSHLD+ ERSDIFDAMFP+ A
Sbjct: 101 SAEVYTEEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIA 160
Query: 591 YETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKASTD 770
ET+IQQGD+GDNFY+IDQGE+++YVN+E +V EGGSFGELALIYGTPRAATVKA T+
Sbjct: 161 GETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVGEGGSFGELALIYGTPRAATVKAKTN 220
Query: 771 VKLWGIDRDSYR 806
VKLWGIDRDSYR
Sbjct: 221 VKLWGIDRDSYR 232
Score = 56.6 bits (135), Expect = 8e-08
Identities = 38/129 (29%), Positives = 61/129 (47%), Gaps = 6/129 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + K + LD+ ER + DA+ P+ + + I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQG 286
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
+ GD F+II +G + N E G FGE+AL+ PRAATV A +K
Sbjct: 287 EPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFGEIALLMNRPRAATVVARGPLK 346
Query: 777 LWGIDRDSY 803
+DR +
Sbjct: 347 CVKLDRPRF 355
>sp|P16905|KAPR1_DROME cAMP-dependent protein kinase type I regulatory subunit (DRI class
I to class IV)
Length = 376
Score = 249 bits (637), Expect = 5e-66
Identities = 135/253 (53%), Positives = 170/253 (67%), Gaps = 1/253 (0%)
Frame = +3
Query: 51 IEELEEYIKKHNIHQLLKDCVVKLCLSKPVSPVSFIREYFQNLEK-QLQKDXXXXXXXXX 227
+ E E YI+ H I ++LKDC+V+LC+ +P +PV F+R+YFQ LE+ Q++ D
Sbjct: 14 LRECEHYIQTHGIQRVLKDCIVQLCVCRPENPVQFLRQYFQKLEREQVKLD--------- 64
Query: 228 XXXXXXHHKKCCSFSHNDSLNELEDHMAGMEIIGLACNVDEYSSVVCSAKDKKARLRRGA 407
A ++I + ++ S + +A R RG
Sbjct: 65 ---------------------------ASRQVIS-PDDCEDLSPMPQTAAPPVRR--RGG 94
Query: 408 VSGEVYTEDDAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKK 587
+S E TE+DA +YVKKVVPKDYKTM+ALSKAI KNVLF+HLDE ERSDIFDAMFP++
Sbjct: 95 ISAEPVTEEDATNYVKKVVPKDYKTMNALSKAIAKNVLFAHLDESERSDIFDAMFPVNHI 154
Query: 588 AYETIIQQGDDGDNFYIIDQGEVEIYVNDELNCNVSEGGSFGELALIYGTPRAATVKAST 767
A E IIQQGD+GDNFY+ID GEV+++VN EL +SEGGSFGELALIYGTPRAATV+A T
Sbjct: 155 AGENIIQQGDEGDNFYVIDVGEVDVFVNSELVTTISEGGSFGELALIYGTPRAATVRAKT 214
Query: 768 DVKLWGIDRDSYR 806
DVKLWGIDRDSYR
Sbjct: 215 DVKLWGIDRDSYR 227
Score = 50.4 bits (119), Expect = 6e-06
Identities = 37/126 (29%), Positives = 60/126 (47%), Gaps = 6/126 (4%)
Frame = +3
Query: 435 DAASYVKKVVPKDYKTMSALSKAIEKNVLFSHLDEKERSDIFDAMFPLHKKAYETIIQQG 614
D SY + ++ + + + + + LD+ ER + D++ ETI++QG
Sbjct: 222 DRDSYRRILMGSTIRKRKMYEEFLSRVSILESLDKWERLTVADSLETCSFDDGETIVKQG 281
Query: 615 DDGDNFYIIDQGEVEIYVNDELNCNVSEGGS------FGELALIYGTPRAATVKASTDVK 776
GD+FYII +G + + +E G FGE+AL+ PRAATV A +K
Sbjct: 282 AAGDDFYIILEGCAVVLQQRSEGEDPAEVGRLGSSDYFGEIALLLDRPRAATVVARGPLK 341
Query: 777 LWGIDR 794
+DR
Sbjct: 342 CVKLDR 347
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 76,860,965
Number of Sequences: 369166
Number of extensions: 1383848
Number of successful extensions: 4414
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4133
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4321
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7666799535
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)