Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00265 (924 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 162 2e-39 sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 160 4e-39 sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 159 8e-39 sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 155 2e-37 sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 155 2e-37 sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 154 3e-37 sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 121 2e-27 sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 74 6e-13 sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 69 1e-11 sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 67 5e-11
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding protein PPTB-1) Length = 531 Score = 162 bits (409), Expect = 2e-39 Identities = 87/173 (50%), Positives = 114/173 (65%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDVQRVKIL+NKK AL+Q DG A A+++LN L+GKP+R+ SKH ++ +P+ Sbjct: 360 VYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPR- 418 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KDY NS LHRFK+ S+ QNI+PP LHL+ +P S E+D++ LF + Sbjct: 419 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNG 478 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 + K RKMAL+QM SVE A+ ALI LH++D G + LRVSFSK I Sbjct: 479 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI 531
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding protein) (PYBP) Length = 555 Score = 160 bits (406), Expect = 4e-39 Identities = 86/173 (49%), Positives = 115/173 (66%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDVQRVKIL+NKK AL++ DG A A+++LN L+GK +R+ SKH S+ +P+ Sbjct: 384 VYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPR- 442 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KDY +S LHRFK+ S+ QNI+PP LHL+ +P S EDD+++LF + Sbjct: 443 EGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNG 502 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 + K RKMAL+QM SVE A+ ALI+LH++D G + LRVSFSK I Sbjct: 503 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI 555
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) Length = 557 Score = 159 bits (403), Expect = 8e-39 Identities = 88/173 (50%), Positives = 113/173 (65%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VY DVQRVKIL+NKK AL+Q DG A A+++LN L+GKP+R+ SKH ++ +P+ Sbjct: 386 VYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSKHQNVQLPR- 444 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KDY NS LHRFK+ S+ QNI+PP LHL+ +P S E+D++ LF + Sbjct: 445 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSISEEDLKILFSSNG 504 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 I K RKMAL+QM SVE AI ALI LH++D G + LRVSFSK I Sbjct: 505 GIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKSTI 557
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) Length = 523 Score = 155 bits (391), Expect = 2e-37 Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+ Sbjct: 352 VYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 410 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 523
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) Length = 521 Score = 155 bits (391), Expect = 2e-37 Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+ Sbjct: 350 VYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 408 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E Sbjct: 409 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAG 468 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I Sbjct: 469 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 521
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) Length = 523 Score = 154 bits (390), Expect = 3e-37 Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+ Sbjct: 352 VYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 410 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 523
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) Length = 527 Score = 121 bits (304), Expect = 2e-27 Identities = 75/173 (43%), Positives = 101/173 (58%), Gaps = 2/173 (1%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 VYGDVQRVKIL+NKK AL+Q DG A + + + + +++ S Sbjct: 358 VYGDVQRVKILFNKKENALVQMADGSQAQ--LGEPPERAQAAREVSAHYTVQASECAAAR 415 Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700 E Q L KDY +S L RFK+ S+ QNI+PP LHL+ +P S EDD+++LF + Sbjct: 416 EGQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNG 474 Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856 + K RKMAL+QM SVE A+ ALI+LH++D G + LRVSFSK I Sbjct: 475 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI 527
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal RNA-regulating factor) (BLOCK24 protein) Length = 542 Score = 73.9 bits (180), Expect = 6e-13 Identities = 51/162 (31%), Positives = 83/162 (51%), Gaps = 7/162 (4%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 520 +YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ + Sbjct: 358 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 417 Query: 521 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 697 E ++ KD++ S+ +RF A + I PP VLH +P E+ L D Sbjct: 418 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 477 Query: 698 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 808 F+ KV P+ + ++ L++ E A++AL L+ Y Sbjct: 478 EVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHY 519
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like Length = 591 Score = 69.3 bits (168), Expect = 1e-11 Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 7/162 (4%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 520 +YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ + Sbjct: 407 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 466 Query: 521 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 697 E ++ KD++ S+ +RF A + I PP VLH +P E+ L D Sbjct: 467 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 526 Query: 698 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 808 F+ KV + + ++ L++ + A++AL L+ Y Sbjct: 527 EVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHY 568
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L) Length = 555 Score = 67.4 bits (163), Expect = 5e-11 Identities = 48/163 (29%), Positives = 81/163 (49%), Gaps = 8/163 (4%) Frame = +2 Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523 +YG+V++VK + +K A+++ DG RA+T+LNN ++G+ M V SK +I MP Sbjct: 371 LYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAI-MPGQ 429 Query: 524 E---EQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFE 694 E S KD+S SR +RF I P VLH P E++ + + Sbjct: 430 SYGLEDGSCSY-KDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICD 488 Query: 695 DFVI---TKVKMINPNQRKMA--LVQMESVEMAIDALIKLHDY 808 + + T VK+ + + + L++ +S A++ L L+ Y Sbjct: 489 ELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHY 531
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 92,904,449 Number of Sequences: 369166 Number of extensions: 1706837 Number of successful extensions: 4011 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3789 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3988 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9462723610 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)