Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_H05
(924 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 162 2e-39
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 160 4e-39
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 159 8e-39
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 155 2e-37
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 155 2e-37
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 154 3e-37
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 121 2e-27
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 74 6e-13
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 69 1e-11
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 67 5e-11
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 162 bits (409), Expect = 2e-39
Identities = 87/173 (50%), Positives = 114/173 (65%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDVQRVKIL+NKK AL+Q DG A A+++LN L+GKP+R+ SKH ++ +P+
Sbjct: 360 VYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPR- 418
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KDY NS LHRFK+ S+ QNI+PP LHL+ +P S E+D++ LF +
Sbjct: 419 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNG 478
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
+ K RKMAL+QM SVE A+ ALI LH++D G + LRVSFSK I
Sbjct: 479 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI 531
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 160 bits (406), Expect = 4e-39
Identities = 86/173 (49%), Positives = 115/173 (66%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDVQRVKIL+NKK AL++ DG A A+++LN L+GK +R+ SKH S+ +P+
Sbjct: 384 VYGDVQRVKILFNKKENALVEMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPR- 442
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KDY +S LHRFK+ S+ QNI+PP LHL+ +P S EDD+++LF +
Sbjct: 443 EGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNG 502
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
+ K RKMAL+QM SVE A+ ALI+LH++D G + LRVSFSK I
Sbjct: 503 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI 555
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 159 bits (403), Expect = 8e-39
Identities = 88/173 (50%), Positives = 113/173 (65%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VY DVQRVKIL+NKK AL+Q DG A A+++LN L+GKP+R+ SKH ++ +P+
Sbjct: 386 VYCDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKPVRITLSKHQNVQLPR- 444
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KDY NS LHRFK+ S+ QNI+PP LHL+ +P S E+D++ LF +
Sbjct: 445 EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSISEEDLKILFSSNG 504
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
I K RKMAL+QM SVE AI ALI LH++D G + LRVSFSK I
Sbjct: 505 GIVKGFKFFQKDRKMALIQMGSVEEAIQALIDLHNHDLGENHHLRVSFSKSTI 557
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 155 bits (391), Expect = 2e-37
Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+
Sbjct: 352 VYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 410
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E
Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I
Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 523
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 155 bits (391), Expect = 2e-37
Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+
Sbjct: 350 VYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 408
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E
Sbjct: 409 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAG 468
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I
Sbjct: 469 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 521
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 154 bits (390), Expect = 3e-37
Identities = 85/173 (49%), Positives = 110/173 (63%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDV RVKI++NKK AL+Q D A A+ +L+ LYGK +R SKH ++ +P+
Sbjct: 352 VYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPR- 410
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KD+SNS LHRFK+ S+ QNI+PP LHL+ +P S DD++NLF E
Sbjct: 411 EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAG 470
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
K RKMAL+Q+ SVE AI ALI+LH++D G + LRVSFSK I
Sbjct: 471 CSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI 523
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 121 bits (304), Expect = 2e-27
Identities = 75/173 (43%), Positives = 101/173 (58%), Gaps = 2/173 (1%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
VYGDVQRVKIL+NKK AL+Q DG A + + + + +++ S
Sbjct: 358 VYGDVQRVKILFNKKENALVQMADGSQAQ--LGEPPERAQAAREVSAHYTVQASECAAAR 415
Query: 524 EEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLF-EDF 700
E Q L KDY +S L RFK+ S+ QNI+PP LHL+ +P S EDD+++LF +
Sbjct: 416 EGQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNG 474
Query: 701 VITKVKMINPNQRKMALVQMESVEMAIDALIKLHDYDAGSS-KLRVSFSKGFI 856
+ K RKMAL+QM SVE A+ ALI+LH++D G + LRVSFSK I
Sbjct: 475 GVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI 527
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 73.9 bits (180), Expect = 6e-13
Identities = 51/162 (31%), Positives = 83/162 (51%), Gaps = 7/162 (4%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 520
+YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ +
Sbjct: 358 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 417
Query: 521 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 697
E ++ KD++ S+ +RF A + I PP VLH +P E+ L D
Sbjct: 418 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 477
Query: 698 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 808
F+ KV P+ + ++ L++ E A++AL L+ Y
Sbjct: 478 EVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEALTALNHY 519
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 69.3 bits (168), Expect = 1e-11
Identities = 49/162 (30%), Positives = 82/162 (50%), Gaps = 7/162 (4%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSK-HTSISMPK 520
+YG++++VK + TAL++ D RAVT+LNNV L+GK + V SK H+ +
Sbjct: 407 LYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHLNNVKLFGKRLNVCVSKQHSVVPSQI 466
Query: 521 PEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFED- 697
E ++ KD++ S+ +RF A + I PP VLH +P E+ L D
Sbjct: 467 FELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPPSCVLHYYNVPLCVTEETFTKLCNDH 526
Query: 698 ----FVITKVKMINPNQRKMA-LVQMESVEMAIDALIKLHDY 808
F+ KV + + ++ L++ + A++AL L+ Y
Sbjct: 527 EVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEALTALNHY 568
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 67.4 bits (163), Expect = 5e-11
Identities = 48/163 (29%), Positives = 81/163 (49%), Gaps = 8/163 (4%)
Frame = +2
Query: 344 VYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNVSLYGKPMRVNFSKHTSISMPKP 523
+YG+V++VK + +K A+++ DG RA+T+LNN ++G+ M V SK +I MP
Sbjct: 371 LYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNNFMFGQKMNVCVSKQPAI-MPGQ 429
Query: 524 E---EQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGTVLHLAGLPDSFEEDDVRNLFE 694
E S KD+S SR +RF I P VLH P E++ + +
Sbjct: 430 SYGLEDGSCSY-KDFSESRNNRFSTPEQAAKNRIQHPSNVLHFFNAPLEVTEENFFEICD 488
Query: 695 DFVI---TKVKMINPNQRKMA--LVQMESVEMAIDALIKLHDY 808
+ + T VK+ + + + L++ +S A++ L L+ Y
Sbjct: 489 ELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLGFLNHY 531
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,904,449
Number of Sequences: 369166
Number of extensions: 1706837
Number of successful extensions: 4011
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3789
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3988
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)