Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_017_N18
(687 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein ... 196 5e-50
sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 ... 195 1e-49
sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 ... 194 2e-49
sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1) 186 6e-47
sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1) 185 8e-47
sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1) 185 1e-46
sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein ... 155 7e-38
sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprote... 90 6e-18
sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprote... 85 2e-16
sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprote... 80 4e-15
>sp|P26599|PTBP1_HUMAN Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (57 kDa RNA-binding
protein PPTB-1)
Length = 531
Score = 196 bits (498), Expect = 5e-50
Identities = 103/200 (51%), Positives = 136/200 (68%), Gaps = 2/200 (1%)
Frame = +1
Query: 31 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 210
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL+Q DG A A++
Sbjct: 333 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMS 392
Query: 211 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 390
+LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S+ QNI+P
Sbjct: 393 HLNGHKLHGKPIRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP 451
Query: 391 PGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKL 567
P LHL+ +P S E+D++ LF + + K RKMAL+QM SVE A+ ALI L
Sbjct: 452 PSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDL 511
Query: 568 HDYDAGSS-KLRVSFSKGFI 624
H++D G + LRVSFSK I
Sbjct: 512 HNHDLGENHHLRVSFSKSTI 531
>sp|Q00438|PTBP1_RAT Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I) (Pyrimidine-binding
protein) (PYBP)
Length = 555
Score = 195 bits (495), Expect = 1e-49
Identities = 102/200 (51%), Positives = 137/200 (68%), Gaps = 2/200 (1%)
Frame = +1
Query: 31 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 210
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL++ DG A A++
Sbjct: 357 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVEMADGSQAQLAMS 416
Query: 211 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 390
+LN L+GK +R+ SKH S+ +P+ E Q L KDY +S LHRFK+ S+ QNI+P
Sbjct: 417 HLNGHKLHGKSVRITLSKHQSVQLPR-EGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFP 475
Query: 391 PGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKL 567
P LHL+ +P S EDD+++LF + + K RKMAL+QM SVE A+ ALI+L
Sbjct: 476 PSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIEL 535
Query: 568 HDYDAGSS-KLRVSFSKGFI 624
H++D G + LRVSFSK I
Sbjct: 536 HNHDLGENHHLRVSFSKSTI 555
>sp|Q29099|PTBP1_PIG Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 557
Score = 194 bits (492), Expect = 2e-49
Identities = 104/200 (52%), Positives = 135/200 (67%), Gaps = 2/200 (1%)
Frame = +1
Query: 31 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 210
G NSV++V+NLN +R+ P +LFILFGVY DVQRVKIL+NKK AL+Q DG A A++
Sbjct: 359 GAGNSVLLVSNLNPERVTPQSLFILFGVYCDVQRVKILFNKKENALVQMADGSQAQLAMS 418
Query: 211 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 390
+LN L+GKP+R+ SKH ++ +P+ E Q L KDY NS LHRFK+ S+ QNI+P
Sbjct: 419 HLNGHKLHGKPVRITLSKHQNVQLPR-EGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFP 477
Query: 391 PGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKL 567
P LHL+ +P S E+D++ LF + I K RKMAL+QM SVE AI ALI L
Sbjct: 478 PSATLHLSNIPPSISEEDLKILFSSNGGIVKGFKFFQKDRKMALIQMGSVEEAIQALIDL 537
Query: 568 HDYDAGSS-KLRVSFSKGFI 624
H++D G + LRVSFSK I
Sbjct: 538 HNHDLGENHHLRVSFSKSTI 557
>sp|O95758|ROD1_HUMAN Regulator of differentiation 1 (Rod1)
Length = 521
Score = 186 bits (471), Expect = 6e-47
Identities = 101/197 (51%), Positives = 128/197 (64%), Gaps = 2/197 (1%)
Frame = +1
Query: 40 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 219
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 326 NSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLS 385
Query: 220 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 399
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 386 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 444
Query: 400 VLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKLHDY 576
LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI ALI+LH++
Sbjct: 445 TLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNH 504
Query: 577 DAGSS-KLRVSFSKGFI 624
D G + LRVSFSK I
Sbjct: 505 DLGENHHLRVSFSKSTI 521
>sp|Q8BHD7|ROD1_MOUSE Regulator of differentiation 1 (Rod1)
Length = 523
Score = 185 bits (470), Expect = 8e-47
Identities = 101/197 (51%), Positives = 128/197 (64%), Gaps = 2/197 (1%)
Frame = +1
Query: 40 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 219
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 328 NSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLS 387
Query: 220 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 399
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 388 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 446
Query: 400 VLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKLHDY 576
LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI ALI+LH++
Sbjct: 447 TLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNH 506
Query: 577 DAGSS-KLRVSFSKGFI 624
D G + LRVSFSK I
Sbjct: 507 DLGENHHLRVSFSKSTI 523
>sp|Q9Z118|ROD1_RAT Regulator of differentiation 1 (Rod1)
Length = 523
Score = 185 bits (469), Expect = 1e-46
Identities = 101/197 (51%), Positives = 128/197 (64%), Gaps = 2/197 (1%)
Frame = +1
Query: 40 NSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLN 219
NSV++V NLN D I P LFILFGVYGDV RVKI++NKK AL+Q D A A+ +L+
Sbjct: 328 NSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLS 387
Query: 220 NVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPGT 399
LYGK +R SKH ++ +P+ E Q L KD+SNS LHRFK+ S+ QNI+PP
Sbjct: 388 GQRLYGKVLRATLSKHQAVQLPR-EGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSA 446
Query: 400 VLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKLHDY 576
LHL+ +P S DD++NLF E K RKMAL+Q+ SVE AI ALI+LH++
Sbjct: 447 TLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNH 506
Query: 577 DAGSS-KLRVSFSKGFI 624
D G + LRVSFSK I
Sbjct: 507 DLGENHHLRVSFSKSTI 523
>sp|P17225|PTBP1_MOUSE Polypyrimidine tract-binding protein 1 (PTB) (Heterogeneous nuclear
ribonucleoprotein I) (hnRNP I)
Length = 527
Score = 155 bits (393), Expect = 7e-38
Identities = 91/200 (45%), Positives = 123/200 (61%), Gaps = 2/200 (1%)
Frame = +1
Query: 31 GNSNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVT 210
G NSV++V+NLN +R+ P +LFILFGVYGDVQRVKIL+NKK AL+Q DG A +
Sbjct: 331 GAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQ--LG 388
Query: 211 NLNNVSLYGKPMRVNFSKHTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYP 390
+ + + +++ S E Q L KDY +S L RFK+ S+ QNI+P
Sbjct: 389 EPPERAQAAREVSAHYTVQASECAAAREGQEDQGLTKDYGSSPL-RFKKPGSKNFQNIFP 447
Query: 391 PGTVLHLAGLPDSFEEDDVRNLF-EDFVITKVKMINPNQRKMALVQMESVEMAIDALIKL 567
P LHL+ +P S EDD+++LF + + K RKMAL+QM SVE A+ ALI+L
Sbjct: 448 PSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIEL 507
Query: 568 HDYDAGSS-KLRVSFSKGFI 624
H++D G + LRVSFSK I
Sbjct: 508 HNHDLGENHHLRVSFSKSTI 527
>sp|Q8WVV9|HNRLL_HUMAN Heterogeneous nuclear ribonucleoprotein L-like (Stromal
RNA-regulating factor) (BLOCK24 protein)
Length = 542
Score = 89.7 bits (221), Expect = 6e-18
Identities = 61/187 (32%), Positives = 100/187 (53%), Gaps = 7/187 (3%)
Frame = +1
Query: 37 SNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNL 216
S SVV+V+ L++ ++N +F LF +YG++++VK + TAL++ D RAVT+L
Sbjct: 333 SGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHL 392
Query: 217 NNVSLYGKPMRVNFSK-HTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPP 393
NNV L+GK + V SK H+ + E ++ KD++ S+ +RF A + I PP
Sbjct: 393 NNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPP 452
Query: 394 GTVLHLAGLPDSFEEDDVRNLFED-----FVITKVKMINPNQRKMA-LVQMESVEMAIDA 555
VLH +P E+ L D F+ KV P+ + ++ L++ E A++A
Sbjct: 453 SCVLHYYNVPLCVTEETFTKLCNDHEVLTFIKYKVFDAKPSAKTLSGLLEWECKTDAVEA 512
Query: 556 LIKLHDY 576
L L+ Y
Sbjct: 513 LTALNHY 519
>sp|Q921F4|HNRLL_MOUSE Heterogeneous nuclear ribonucleoprotein L-like
Length = 591
Score = 85.1 bits (209), Expect = 2e-16
Identities = 59/187 (31%), Positives = 99/187 (52%), Gaps = 7/187 (3%)
Frame = +1
Query: 37 SNSVVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNL 216
S SVV+V+ L++ ++N +F LF +YG++++VK + TAL++ D RAVT+L
Sbjct: 382 SGSVVMVSGLHQLKMNCSRVFNLFCLYGNIEKVKFMKTIPGTALVEMGDEYAVERAVTHL 441
Query: 217 NNVSLYGKPMRVNFSK-HTSISMPKPEEQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPP 393
NNV L+GK + V SK H+ + E ++ KD++ S+ +RF A + I PP
Sbjct: 442 NNVKLFGKRLNVCVSKQHSVVPSQIFELEDGTSSYKDFAMSKNNRFTSAGQASKNIIQPP 501
Query: 394 GTVLHLAGLPDSFEEDDVRNLFED-----FVITKVKMINPNQRKMA-LVQMESVEMAIDA 555
VLH +P E+ L D F+ KV + + ++ L++ + A++A
Sbjct: 502 SCVLHYYNVPLCVTEETFTKLCNDHEVLPFIKYKVFDAKASAKTLSGLLEWKCKTDAVEA 561
Query: 556 LIKLHDY 576
L L+ Y
Sbjct: 562 LTALNHY 568
>sp|Q8R081|HNRPL_MOUSE Heterogeneous nuclear ribonucleoprotein L (hnRNP L)
Length = 555
Score = 80.5 bits (197), Expect = 4e-15
Identities = 55/185 (29%), Positives = 96/185 (51%), Gaps = 8/185 (4%)
Frame = +1
Query: 46 VVIVANLNEDRINPDALFILFGVYGDVQRVKILYNKKNTALIQFVDGEHASRAVTNLNNV 225
V++V L++ ++N D +F +F +YG+V++VK + +K A+++ DG RA+T+LNN
Sbjct: 349 VLMVYGLDQSKMNCDRVFNVFCLYGNVEKVKFMKSKPGAAMVEMADGYAVDRAITHLNNN 408
Query: 226 SLYGKPMRVNFSKHTSISMPKPE---EQNSVHLNKDYSNSRLHRFKRATSRTVQNIYPPG 396
++G+ M V SK +I MP E S KD+S SR +RF I P
Sbjct: 409 FMFGQKMNVCVSKQPAI-MPGQSYGLEDGSCSY-KDFSESRNNRFSTPEQAAKNRIQHPS 466
Query: 397 TVLHLAGLPDSFEEDDVRNLFEDFVI---TKVKMINPNQRKMA--LVQMESVEMAIDALI 561
VLH P E++ + ++ + T VK+ + + + L++ +S A++ L
Sbjct: 467 NVLHFFNAPLEVTEENFFEICDELGVKRPTSVKVFSGKSERSSSGLLEWDSKSDALETLG 526
Query: 562 KLHDY 576
L+ Y
Sbjct: 527 FLNHY 531
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,819,550
Number of Sequences: 369166
Number of extensions: 1448657
Number of successful extensions: 3794
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3594
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3767
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5879188535
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)