Planaria EST Database


DrC_00197

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00197
         (938 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q94887|NRX4_DROME  Neurexin-4 precursor (Neurexin IV)          193   5e-49
sp|Q99P47|CNTP4_MOUSE  Contactin-associated protein-like 4 p...   135   2e-31
sp|Q9C0A0|CNTP4_HUMAN  Contactin-associated protein-like 4 p...   130   7e-30
sp|Q9BZ76|CNTP3_HUMAN  Contactin-associated protein-like 3 p...   126   1e-28
sp|Q5RD64|CNTP2_PONPY  Contactin-associated protein-like 2 p...   120   6e-27
sp|Q9UHC6|CNTP2_HUMAN  Contactin-associated protein-like 2 p...   117   4e-26
sp|Q9CPW0|CNTP2_MOUSE  Contactin-associated protein-like 2 p...   117   4e-26
sp|P97846|CNTP1_RAT  Contactin-associated protein 1 precurso...   102   2e-21
sp|P78357|CNTP1_HUMAN  Contactin-associated protein 1 precur...   102   2e-21
sp|O54991|CNTP1_MOUSE  Contactin-associated protein 1 precur...    99   1e-20
>sp|Q94887|NRX4_DROME Neurexin-4 precursor (Neurexin IV)
          Length = 1284

 Score =  193 bits (491), Expect = 5e-49
 Identities = 109/298 (36%), Positives = 158/298 (53%), Gaps = 2/298 (0%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPLRC GD LF N +TF   DA INLPP    +  D+   F+TT  N+VI  +    +  
Sbjct: 784  GPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATGPTD-- 841

Query: 183  FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359
            + ++ +  G  L+  +                  DN WH V  ERNRKE+RL++D +   
Sbjct: 842  YIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKA 901

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKS-AITDYYGISN 536
               E P  P    +  SDL++G++  + DGYVGC   L++NG + DLK  +    YGIS 
Sbjct: 902  EVREPPG-PVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGIST 960

Query: 537  GCNPKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLDYFD 716
            GC  +C S PCLN G C E Y GY C+C  + ++G +C  E+G +    S   I+ ++  
Sbjct: 961  GCVGRCESNPCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSI--IRYEFEG 1018

Query: 717  QKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNGGITIEFDVGFTRYEV 890
               ST+ E I +GF T   +G LL  SS    +Y+ I+++N+G +   FD GF R E+
Sbjct: 1019 SFRSTIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEI 1076

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 51/217 (23%), Positives = 83/217 (38%), Gaps = 15/217 (6%)
 Frame = +3

Query: 45  ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224
           +TFT   + + L         ++ F F+T     V+L      +G + +V +  G     
Sbjct: 377 VTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHH-DFYSGGYLKVFLEFGKVKID 435

Query: 225 TFXXXXXXXXXXXXXXXXXDNFWH--VVRFERNRKESRLILDENAPVTHSEDPDRPFTTF 398
                              D  WH  V+  E+NR    LIL+ +          RP TT 
Sbjct: 436 LKVKDKARIILDNYDDQFNDGKWHSFVISIEKNR----LILNID---------QRPMTTT 482

Query: 399 NFDSDLLLGSSQSFT-----DGYVGCFSNLIVNG---VVQDLKSAITDYYG---ISNGCN 545
                +  G+          +G+VGC   + V+G   + QD         G   + + C 
Sbjct: 483 K-SMQVATGAQYYIAGGKDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQ 541

Query: 546 --PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVC 650
              +CN  PC ++G C++    ++C+CG T Y G VC
Sbjct: 542 MIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVC 578

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 6/123 (4%)
 Frame = +3

Query: 123  FKTTVANAVILQSVSKLNGQFFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXXDNFWHVV 302
            F TT+    +L   S L G++  ++I     LR  F                    +H +
Sbjct: 1032 FTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDM 1091

Query: 303  RFERNRKESRLIL--DENAPVTHSED----PDRPFTTFNFDSDLLLGSSQSFTDGYVGCF 464
             F R    S ++L  D   PV ++ D     D  F    +   + +G ++S TDG+VGC 
Sbjct: 1092 HFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQY---MYIGKNESMTDGFVGCV 1148

Query: 465  SNL 473
            S +
Sbjct: 1149 SRV 1151

 Score = 35.4 bits (80), Expect = 0.23
 Identities = 34/159 (21%), Positives = 64/159 (40%), Gaps = 6/159 (3%)
 Frame = +3

Query: 24  DSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIR 203
           ++L+ N     ++D  +   P+ +  E  + F FKT  AN V++ S     G ++ ++++
Sbjct: 190 ENLYFNGTGLVRYD--LRREPITSTKE-SIRFRFKTAFANGVMMYSRGT-QGDYYALQLK 245

Query: 204 EGFTLRVTFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPVTHSEDPDR 383
           +   + +                   DN WH V   RN+++    +D    V        
Sbjct: 246 DN-KMVLNLDLGSRVMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDR---VIVRGRIQG 301

Query: 384 PFTTFNFDSDLLLGSSQSFTDGYV------GCFSNLIVN 482
            FT  N + +L LG   +  +G +      GC  N+  N
Sbjct: 302 EFTRLNLNRELYLGGVPNVQEGLIVQQNFSGCLENIYFN 340
>sp|Q99P47|CNTP4_MOUSE Contactin-associated protein-like 4 precursor (Cell recognition
            molecule Caspr4)
          Length = 1310

 Score =  135 bits (339), Expect = 2e-31
 Identities = 90/306 (29%), Positives = 140/306 (45%), Gaps = 19/306 (6%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPL C GD  F N  +F    + ++ P    E   D+ F FKTT  + V L+++   +  
Sbjct: 783  GPLLCRGDRPFWNAASFNTEASYLHFPTFHGELSADVSFFFKTTALSGVFLENLGITD-- 840

Query: 183  FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359
            F  + +R   T+  +F                  DN WH VR ERN KE+ L +DE  P 
Sbjct: 841  FIRIELRSPTTVTFSFDVGNGPFELSVHSPTHFNDNQWHHVRVERNMKEASLRVDELPPK 900

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
              +   D        +S L +G + +   G++GC  +L +NG+  DL+   T   G+  G
Sbjct: 901  IQAAPTDG-HVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMALDLEERATVTPGVQPG 959

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLD-- 707
            C   C S  K C + G+C E  SG++C+C  + + G  C +E+ A F  GS++       
Sbjct: 960  CRGHCGSYGKLCRHGGKCREKPSGFFCDCSSSAFAGPFCSKEISAYFGSGSSVIYNFQEN 1019

Query: 708  --------------YFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNG 845
                          + D K+S   E I+  F+T      LL +SS+ YK+Y+ I +  NG
Sbjct: 1020 YSLSKNSSFHAASFHGDMKLS--REMIKFSFRTTRAPSLLLHMSSF-YKEYLSIIIAKNG 1076

Query: 846  GITIEF 863
             + I +
Sbjct: 1077 SLQIRY 1082

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 50/219 (22%), Positives = 88/219 (40%), Gaps = 13/219 (5%)
 Frame = +3

Query: 45   ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224
            +TF    + + LP    E      F F+T     ++L S  +L      + + +G  L++
Sbjct: 374  LTFLSPRSYLVLPASTKEEAISASFQFRTWNKAGLLLFSELQLVSGSLLLLLSDG-KLKL 432

Query: 225  TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDEN-APVTHSEDPDRPFT--T 395
            T                  D  WH V     R    +++D + +P +    P++  +   
Sbjct: 433  TLYQPGKSPSDITAGAGLGDGQWHSVSLSAKRNHLSVVVDGHISPASPWLGPEQVNSGGV 492

Query: 396  FNFDS--DLLLGSS-QSFTDGYVGCFSNLIVNGVVQDL----KSAITDYYGI---SNGCN 545
            F F    D   GS  +S   G+ GC   + +N  + DL    + A+ ++  +   S G +
Sbjct: 493  FYFGGCPDKGFGSKCKSPLGGFQGCMRLISINNKMVDLIAVQQGALGNFSDLQIDSCGIS 552

Query: 546  PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662
             +C    C + GEC + +S ++C C  T Y G  C   V
Sbjct: 553  DRCLPNSCEHGGECSQSWSTFHCNCTNTGYTGATCHSSV 591
>sp|Q9C0A0|CNTP4_HUMAN Contactin-associated protein-like 4 precursor (Cell recognition
            molecule Caspr4)
          Length = 1308

 Score =  130 bits (326), Expect = 7e-30
 Identities = 88/306 (28%), Positives = 137/306 (44%), Gaps = 19/306 (6%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPL C GD  F N+ +F    + ++ P    E   D+ F FKTT ++ V L+++      
Sbjct: 781  GPLLCRGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLG--IAD 838

Query: 183  FFEVRIREGFTLRVTF-XXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPV 359
            F  + +R    +  +F                  DN WH VR ERN KE+ L +D+  P 
Sbjct: 839  FIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPK 898

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
            T     D        +S L +G + +   G++GC  +L +NG+  DL+        +  G
Sbjct: 899  TQPAPAD-GHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPG 957

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLD-- 707
            C   C+S  K C N G+C E   G++C+C  + Y G  C  E+ A F  GS++       
Sbjct: 958  CRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQEN 1017

Query: 708  --------------YFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNG 845
                          + D K+S   E I+  F+T      LL VSS+ YK+Y+ + +  NG
Sbjct: 1018 YLLSKNSSSHAASFHGDMKLS--REMIKFSFRTTRTPSLLLFVSSF-YKEYLSVIIAKNG 1074

Query: 846  GITIEF 863
             + I +
Sbjct: 1075 SLQIRY 1080

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 13/219 (5%)
 Frame = +3

Query: 45   ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224
            +TF    + + LP    E E    F F+T     ++L S  +L      + + +G  L+ 
Sbjct: 372  VTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDG-KLKS 430

Query: 225  TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDPDRPFT--T 395
                               D  WH V     +    + +D + A       P++ ++  T
Sbjct: 431  NLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGT 490

Query: 396  FNFDS--DLLLGSS-QSFTDGYVGCFSNLIVNGVVQDLKSA-------ITDYYGISNGCN 545
            + F    D   GS  +S   G+ GC   + ++G V DL S         +D    S G +
Sbjct: 491  YYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGIS 550

Query: 546  PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662
             +C    C + GEC + +S ++C C  T YRG  C   +
Sbjct: 551  DRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSI 589

 Score = 32.0 bits (71), Expect = 2.6
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 7/76 (9%)
 Frame = +3

Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLL------GSSQSFT 443
           D  WH V  +R  K+    +DE+    H+      F   N D ++        G S SF 
Sbjct: 269 DQHWHSVLIQRLGKQVNFTVDEHRHHFHARG---EFNLMNLDYEISFGGIPAPGKSVSFP 325

Query: 444 D-GYVGCFSNLIVNGV 488
              + GC  NL  NGV
Sbjct: 326 HRNFHGCLENLYYNGV 341
>sp|Q9BZ76|CNTP3_HUMAN Contactin-associated protein-like 3 precursor (Cell recognition
            molecule Caspr3)
          Length = 1288

 Score =  126 bits (316), Expect = 1e-28
 Identities = 84/304 (27%), Positives = 135/304 (44%), Gaps = 17/304 (5%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPL C GD  F N+ +F    + ++ P    E   D+ F FKTTV++ V ++++   +  
Sbjct: 781  GPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITD-- 838

Query: 183  FFEVRIREGFTLRVTF-XXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPV 359
            F  + +R    +  +F                  DN WH VR ERN K + L +D+  P 
Sbjct: 839  FIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ-LPQ 897

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
                 P         +S L +G + +   G++GC  +L +NGV  DL+   T   G+  G
Sbjct: 898  KMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPG 957

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIK---- 701
            C   C++    C N G C E   G  C+C  + Y G  C  E+ A F  GS++       
Sbjct: 958  CAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEH 1017

Query: 702  ----------LDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNGGI 851
                      +    + ++   E I + F+T      LL VSS+ Y++Y+ + + NNG +
Sbjct: 1018 YTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSF-YEEYLSVILANNGSL 1076

Query: 852  TIEF 863
             I +
Sbjct: 1077 QIRY 1080

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 45/220 (20%), Positives = 78/220 (35%), Gaps = 18/220 (8%)
 Frame = +3

Query: 45   ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224
            +TF    + + LP    E++  + F F+T      +L    +     F + +++G  L++
Sbjct: 372  VTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDG-KLKL 430

Query: 225  TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNF 404
            +                  D  WH V F        +++D++  V       +P      
Sbjct: 431  SLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAV-------QPLVAVLI 483

Query: 405  DS----------DLLLGSS-QSFTDGYVGCFSNLIVNG-------VVQDLKSAITDYYGI 530
            DS          D   GS  +S   G+ GC   + +         V Q    +  D    
Sbjct: 484  DSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQID 543

Query: 531  SNGCNPKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVC 650
            S G   +C    C + GEC + +  + C+C  T Y G  C
Sbjct: 544  SCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
>sp|Q5RD64|CNTP2_PONPY Contactin-associated protein-like 2 precursor
          Length = 1331

 Score =  120 bits (301), Expect = 6e-27
 Identities = 91/335 (27%), Positives = 145/335 (43%), Gaps = 23/335 (6%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPLRC GD  + N  +F    + ++      E   D+ F FKT     V L+++ K +  
Sbjct: 787  GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKED-- 844

Query: 183  FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359
            F ++ ++    +  +F                  D+ WH +  ERN K++ L +D   P 
Sbjct: 845  FIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRITAERNVKQASLQVDR-LPQ 903

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
               + P    T     S L +G +     G++GC  +L +NGV  DL+       G  +G
Sbjct: 904  QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISG 962

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDG---------- 683
            C+  C S    C N G+C E Y GY C+C  T Y G  C ++VGA F +G          
Sbjct: 963  CSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022

Query: 684  --------SALEIKLDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNN 839
                    S +E   D  +      +E I   F T      LL +SS+    ++ + V  
Sbjct: 1023 ATNARDSSSRVENAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT-TDFLAVLVKP 1081

Query: 840  NGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938
             G + I +++G TR  Y + TD+  ++ N Q H++
Sbjct: 1082 TGSLQIRYNLGGTREPYNIDTDH-RNMANGQPHSV 1115

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 38/218 (17%), Positives = 71/218 (32%), Gaps = 14/218 (6%)
 Frame = +3

Query: 51   FTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFT-LRVT 227
            F    + + +P    ++ F + F F+T   N +++ S    N    E+ + E    + + 
Sbjct: 377  FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436

Query: 228  FXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPF 389
                              D  WH VRF      + L +D + A    +  P        +
Sbjct: 437  ITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKY 496

Query: 390  TTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNGCN-------P 548
                F + +   S       + GC   + V+  + +L        G     +        
Sbjct: 497  FFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIID 556

Query: 549  KCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662
            +C    C   G+C + +  + C C  T Y G  C   +
Sbjct: 557  RCVPNHCERGGKCSQTWDSFKCTCDETGYTGATCHNSI 594
>sp|Q9UHC6|CNTP2_HUMAN Contactin-associated protein-like 2 precursor (Cell recognition
            molecule Caspr2)
          Length = 1331

 Score =  117 bits (294), Expect = 4e-26
 Identities = 90/335 (26%), Positives = 144/335 (42%), Gaps = 23/335 (6%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPLRC GD  + N  +F    + ++      E   D+ F FKT     V L+++ K +  
Sbjct: 787  GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKED-- 844

Query: 183  FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359
            F ++ ++    +  +F                  D+ WH V  ERN K++ L +D   P 
Sbjct: 845  FIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR-LPQ 903

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
               + P    T     S L +G +     G++GC  +L +NGV  DL+       G  +G
Sbjct: 904  QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISG 962

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDG---------- 683
            C+  C S    C N G+C E Y GY C+C  T Y G  C ++VGA F +G          
Sbjct: 963  CSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022

Query: 684  --------SALEIKLDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNN 839
                    S ++   D  +      +E I   F T      LL +SS+    ++ + V  
Sbjct: 1023 ATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT-TDFLAVLVKP 1081

Query: 840  NGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938
             G + I +++G TR  Y +  D+  ++ N Q H++
Sbjct: 1082 TGSLQIRYNLGGTREPYNIDVDH-RNMANGQPHSV 1115

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 38/218 (17%), Positives = 72/218 (33%), Gaps = 14/218 (6%)
 Frame = +3

Query: 51   FTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFT-LRVT 227
            F    + + +P    ++ F + F F+T   N +++ S    N    E+ + E    + + 
Sbjct: 377  FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436

Query: 228  FXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPF 389
                              D  WH VRF      + L +D + A    +  P        +
Sbjct: 437  ITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKY 496

Query: 390  TTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNGCN-------P 548
                F + +   S       + GC   + V+  + +L        G     +        
Sbjct: 497  FFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIID 556

Query: 549  KCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662
            +C    C + G+C + +  + C C  T Y G  C   +
Sbjct: 557  RCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSI 594
>sp|Q9CPW0|CNTP2_MOUSE Contactin-associated protein-like 2 precursor (Cell recognition
            molecule Caspr2)
          Length = 1332

 Score =  117 bits (294), Expect = 4e-26
 Identities = 92/336 (27%), Positives = 142/336 (42%), Gaps = 24/336 (7%)
 Frame = +3

Query: 3    GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182
            GPLRC GD  + N  +F    + ++      E   D+ F FKT +   V L+++   N  
Sbjct: 787  GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLG--NTD 844

Query: 183  FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359
            F ++ ++    +  +F                  D+ WH V  ERN K++ L +D   P 
Sbjct: 845  FIKLELKSATEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDR-LPQ 903

Query: 360  THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539
               + P    T     S L +G +     G++GC  +L +NGV  DL+       G  +G
Sbjct: 904  QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFKSG 962

Query: 540  CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFID----------- 680
            C+  C S    C N G+C E Y GY C+C  T Y G  C ++VGA F +           
Sbjct: 963  CSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022

Query: 681  -------GSALEIKLDYFDQKISTL-EEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVN 836
                   GS  E   D        L +E I   F T      LL VSS     ++ + V 
Sbjct: 1023 AVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSSLT-TDFLAVLVK 1081

Query: 837  NNGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938
              G + I +++G TR  + +  D+  ++ N Q H++
Sbjct: 1082 PTGNLQIRYNLGGTREPFNIDVDH-RNMANGQPHSV 1116

 Score = 30.8 bits (68), Expect = 5.8
 Identities = 29/144 (20%), Positives = 50/144 (34%), Gaps = 17/144 (11%)
 Frame = +3

Query: 282 DNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPFTTFNFDSDLLLGSSQSFT 443
           D  WH VRF      + L +D + A    +  P        +    F + +   S  +  
Sbjct: 455 DGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNHMNNASYSALQ 514

Query: 444 DGYVGCFSNLIVNGVVQDL-----------KSAITDYYGISNGCNPKCNSKPCLNRGECY 590
             + GC   + V+  + +L            +   D   I + C P      C + G+C 
Sbjct: 515 PSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVTIDMCAIIDRCVPN----HCEHGGKCS 570

Query: 591 EMYSGYYCECGLTPYRGYVCGREV 662
           + +  + C C  T Y G  C   +
Sbjct: 571 QTWDSFKCTCDETGYSGATCHNSI 594
>sp|P97846|CNTP1_RAT Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin
            4) (Neurexin IV) (p190) (Paranodin)
          Length = 1381

 Score =  102 bits (254), Expect = 2e-21
 Identities = 71/244 (29%), Positives = 109/244 (44%), Gaps = 11/244 (4%)
 Frame = +3

Query: 6    PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185
            PLRC GD    NTI+F +  A +  PP+ A +  D+ F F+T+  + V L++   + G F
Sbjct: 776  PLRCYGDRNSWNTISF-RTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLEN---MGGPF 831

Query: 186  FE-----VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLI 338
             +     VR+    +  V F                     D+ WH+VR E N K++RL 
Sbjct: 832  CQWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLR 891

Query: 339  LDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITD 518
            +D   P      P + +    +D  L +GS++     +VGC   + +NGV  +L+     
Sbjct: 892  VDHR-PWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA 950

Query: 519  YYGISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSAL 692
              G    C   C     PC + G C E YS Y C+C LT + G  C  ++G  F  G+ +
Sbjct: 951  SEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWM 1010

Query: 693  EIKL 704
               L
Sbjct: 1011 RYNL 1014

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%)
 Frame = +3

Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440
           D FWH V F         +  EN  V   +D +      ++   +  G+S  F       
Sbjct: 442 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 492

Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563
                      + GC   L V+G + +L              + D  GI++ C+P     
Sbjct: 493 SRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNM--- 549

Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650
            C + G CY+ +  + C C LT Y+G  C
Sbjct: 550 -CEHDGRCYQSWDDFICYCELTGYKGVTC 577
>sp|P78357|CNTP1_HUMAN Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin
            4) (Neurexin IV) (p190)
          Length = 1384

 Score =  102 bits (253), Expect = 2e-21
 Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 8/241 (3%)
 Frame = +3

Query: 6    PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185
            PLRC GD    NTI+F    A +  PP+ A +  D+ F F+T+  + V L+++     Q+
Sbjct: 775  PLRCYGDRNSWNTISFHT-GAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQW 833

Query: 186  FE--VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLILDE 347
                VR+    +  V F                     D+ WH+VR E N K++RL +D 
Sbjct: 834  RRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH 893

Query: 348  NAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYG 527
              P      P + +    +D  L +GS++     +VGC   + +NGV  +L+       G
Sbjct: 894  R-PWVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEG 952

Query: 528  ISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIK 701
             S  C   C     PC + G C E YS Y C+C LT + G  C  ++G  F  G+ +   
Sbjct: 953  TSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYN 1012

Query: 702  L 704
            L
Sbjct: 1013 L 1013

 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%)
 Frame = +3

Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440
           D FWH V F         +  EN  V   +D +      ++   +  G+S  F       
Sbjct: 441 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 491

Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563
                      + GC   L V+G + +L              + D  GI++ C+P     
Sbjct: 492 SRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNM--- 548

Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650
            C + G CY+ +  + C C LT Y+G  C
Sbjct: 549 -CEHDGRCYQSWDDFICYCELTGYKGETC 576
>sp|O54991|CNTP1_MOUSE Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin
            4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV)
          Length = 1385

 Score = 99.4 bits (246), Expect = 1e-20
 Identities = 71/244 (29%), Positives = 107/244 (43%), Gaps = 11/244 (4%)
 Frame = +3

Query: 6    PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185
            PLRC GD    NTI+F    A +  PP+ A +  D+ F F+T+  + V L++   + G F
Sbjct: 776  PLRCYGDRNSWNTISFHT-GAALRFPPIRANHSLDVSFYFRTSAPSGVFLEN---MGGPF 831

Query: 186  FE-----VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLI 338
                   VR+    +  V F                     D+ WH+VR E N K++RL 
Sbjct: 832  CRWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLR 891

Query: 339  LDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITD 518
            +D   P      P + +    +D  L +GS++     +VGC   + +NGV  +L+     
Sbjct: 892  VDHR-PWVLRPMPLQTYIWLVYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA 950

Query: 519  YYGISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSAL 692
              G    C   C     PC + G C E YS Y C+C LT + G  C  ++G  F  G+ +
Sbjct: 951  SEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWM 1010

Query: 693  EIKL 704
               L
Sbjct: 1011 RYNL 1014

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%)
 Frame = +3

Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440
           D FWH V F         +  EN  V   +D +      ++   +  G+S  F       
Sbjct: 442 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 492

Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563
                      + GC   L V+G + +L              + D  GI++ C+P     
Sbjct: 493 SRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNM--- 549

Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650
            C + G CY+ +  + C C LT Y+G  C
Sbjct: 550 -CEHDGRCYQSWDDFICYCELTGYKGVTC 577
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,770,340
Number of Sequences: 369166
Number of extensions: 1984715
Number of successful extensions: 6368
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5076
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6263
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9702894260
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00197

  1. Dr_sW_005_P08
  2. Dr_sW_019_B09