Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00197 (938 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q94887|NRX4_DROME Neurexin-4 precursor (Neurexin IV) 193 5e-49 sp|Q99P47|CNTP4_MOUSE Contactin-associated protein-like 4 p... 135 2e-31 sp|Q9C0A0|CNTP4_HUMAN Contactin-associated protein-like 4 p... 130 7e-30 sp|Q9BZ76|CNTP3_HUMAN Contactin-associated protein-like 3 p... 126 1e-28 sp|Q5RD64|CNTP2_PONPY Contactin-associated protein-like 2 p... 120 6e-27 sp|Q9UHC6|CNTP2_HUMAN Contactin-associated protein-like 2 p... 117 4e-26 sp|Q9CPW0|CNTP2_MOUSE Contactin-associated protein-like 2 p... 117 4e-26 sp|P97846|CNTP1_RAT Contactin-associated protein 1 precurso... 102 2e-21 sp|P78357|CNTP1_HUMAN Contactin-associated protein 1 precur... 102 2e-21 sp|O54991|CNTP1_MOUSE Contactin-associated protein 1 precur... 99 1e-20
>sp|Q94887|NRX4_DROME Neurexin-4 precursor (Neurexin IV) Length = 1284 Score = 193 bits (491), Expect = 5e-49 Identities = 109/298 (36%), Positives = 158/298 (53%), Gaps = 2/298 (0%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPLRC GD LF N +TF DA INLPP + D+ F+TT N+VI + + Sbjct: 784 GPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATGPTD-- 841 Query: 183 FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359 + ++ + G L+ + DN WH V ERNRKE+RL++D + Sbjct: 842 YIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKA 901 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKS-AITDYYGISN 536 E P P + SDL++G++ + DGYVGC L++NG + DLK + YGIS Sbjct: 902 EVREPPG-PVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGIST 960 Query: 537 GCNPKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLDYFD 716 GC +C S PCLN G C E Y GY C+C + ++G +C E+G + S I+ ++ Sbjct: 961 GCVGRCESNPCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSI--IRYEFEG 1018 Query: 717 QKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNGGITIEFDVGFTRYEV 890 ST+ E I +GF T +G LL SS +Y+ I+++N+G + FD GF R E+ Sbjct: 1019 SFRSTIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEI 1076
Score = 47.0 bits (110), Expect = 8e-05 Identities = 51/217 (23%), Positives = 83/217 (38%), Gaps = 15/217 (6%) Frame = +3 Query: 45 ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224 +TFT + + L ++ F F+T V+L +G + +V + G Sbjct: 377 VTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHH-DFYSGGYLKVFLEFGKVKID 435 Query: 225 TFXXXXXXXXXXXXXXXXXDNFWH--VVRFERNRKESRLILDENAPVTHSEDPDRPFTTF 398 D WH V+ E+NR LIL+ + RP TT Sbjct: 436 LKVKDKARIILDNYDDQFNDGKWHSFVISIEKNR----LILNID---------QRPMTTT 482 Query: 399 NFDSDLLLGSSQSFT-----DGYVGCFSNLIVNG---VVQDLKSAITDYYG---ISNGCN 545 + G+ +G+VGC + V+G + QD G + + C Sbjct: 483 K-SMQVATGAQYYIAGGKDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQ 541 Query: 546 --PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVC 650 +CN PC ++G C++ ++C+CG T Y G VC Sbjct: 542 MIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVC 578
Score = 42.4 bits (98), Expect = 0.002 Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 6/123 (4%) Frame = +3 Query: 123 FKTTVANAVILQSVSKLNGQFFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXXDNFWHVV 302 F TT+ +L S L G++ ++I LR F +H + Sbjct: 1032 FTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDM 1091 Query: 303 RFERNRKESRLIL--DENAPVTHSED----PDRPFTTFNFDSDLLLGSSQSFTDGYVGCF 464 F R S ++L D PV ++ D D F + + +G ++S TDG+VGC Sbjct: 1092 HFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQY---MYIGKNESMTDGFVGCV 1148 Query: 465 SNL 473 S + Sbjct: 1149 SRV 1151
Score = 35.4 bits (80), Expect = 0.23 Identities = 34/159 (21%), Positives = 64/159 (40%), Gaps = 6/159 (3%) Frame = +3 Query: 24 DSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIR 203 ++L+ N ++D + P+ + E + F FKT AN V++ S G ++ ++++ Sbjct: 190 ENLYFNGTGLVRYD--LRREPITSTKE-SIRFRFKTAFANGVMMYSRGT-QGDYYALQLK 245 Query: 204 EGFTLRVTFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPVTHSEDPDR 383 + + + DN WH V RN+++ +D V Sbjct: 246 DN-KMVLNLDLGSRVMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDR---VIVRGRIQG 301 Query: 384 PFTTFNFDSDLLLGSSQSFTDGYV------GCFSNLIVN 482 FT N + +L LG + +G + GC N+ N Sbjct: 302 EFTRLNLNRELYLGGVPNVQEGLIVQQNFSGCLENIYFN 340
>sp|Q99P47|CNTP4_MOUSE Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4) Length = 1310 Score = 135 bits (339), Expect = 2e-31 Identities = 90/306 (29%), Positives = 140/306 (45%), Gaps = 19/306 (6%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPL C GD F N +F + ++ P E D+ F FKTT + V L+++ + Sbjct: 783 GPLLCRGDRPFWNAASFNTEASYLHFPTFHGELSADVSFFFKTTALSGVFLENLGITD-- 840 Query: 183 FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359 F + +R T+ +F DN WH VR ERN KE+ L +DE P Sbjct: 841 FIRIELRSPTTVTFSFDVGNGPFELSVHSPTHFNDNQWHHVRVERNMKEASLRVDELPPK 900 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 + D +S L +G + + G++GC +L +NG+ DL+ T G+ G Sbjct: 901 IQAAPTDG-HVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMALDLEERATVTPGVQPG 959 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLD-- 707 C C S K C + G+C E SG++C+C + + G C +E+ A F GS++ Sbjct: 960 CRGHCGSYGKLCRHGGKCREKPSGFFCDCSSSAFAGPFCSKEISAYFGSGSSVIYNFQEN 1019 Query: 708 --------------YFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNG 845 + D K+S E I+ F+T LL +SS+ YK+Y+ I + NG Sbjct: 1020 YSLSKNSSFHAASFHGDMKLS--REMIKFSFRTTRAPSLLLHMSSF-YKEYLSIIIAKNG 1076 Query: 846 GITIEF 863 + I + Sbjct: 1077 SLQIRY 1082
Score = 48.1 bits (113), Expect = 3e-05 Identities = 50/219 (22%), Positives = 88/219 (40%), Gaps = 13/219 (5%) Frame = +3 Query: 45 ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224 +TF + + LP E F F+T ++L S +L + + +G L++ Sbjct: 374 LTFLSPRSYLVLPASTKEEAISASFQFRTWNKAGLLLFSELQLVSGSLLLLLSDG-KLKL 432 Query: 225 TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDEN-APVTHSEDPDRPFT--T 395 T D WH V R +++D + +P + P++ + Sbjct: 433 TLYQPGKSPSDITAGAGLGDGQWHSVSLSAKRNHLSVVVDGHISPASPWLGPEQVNSGGV 492 Query: 396 FNFDS--DLLLGSS-QSFTDGYVGCFSNLIVNGVVQDL----KSAITDYYGI---SNGCN 545 F F D GS +S G+ GC + +N + DL + A+ ++ + S G + Sbjct: 493 FYFGGCPDKGFGSKCKSPLGGFQGCMRLISINNKMVDLIAVQQGALGNFSDLQIDSCGIS 552 Query: 546 PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662 +C C + GEC + +S ++C C T Y G C V Sbjct: 553 DRCLPNSCEHGGECSQSWSTFHCNCTNTGYTGATCHSSV 591
>sp|Q9C0A0|CNTP4_HUMAN Contactin-associated protein-like 4 precursor (Cell recognition molecule Caspr4) Length = 1308 Score = 130 bits (326), Expect = 7e-30 Identities = 88/306 (28%), Positives = 137/306 (44%), Gaps = 19/306 (6%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPL C GD F N+ +F + ++ P E D+ F FKTT ++ V L+++ Sbjct: 781 GPLLCRGDRSFWNSASFDTEASYLHFPTFHGELSADVSFFFKTTASSGVFLENLG--IAD 838 Query: 183 FFEVRIREGFTLRVTF-XXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPV 359 F + +R + +F DN WH VR ERN KE+ L +D+ P Sbjct: 839 FIRIELRSPTVVTFSFDVGNGPFEISVQSPTHFNDNQWHHVRVERNMKEASLQVDQLTPK 898 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 T D +S L +G + + G++GC +L +NG+ DL+ + G Sbjct: 899 TQPAPAD-GHVLLQLNSQLFVGGTATRQRGFLGCIRSLQLNGMTLDLEERAQVTPEVQPG 957 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIKLD-- 707 C C+S K C N G+C E G++C+C + Y G C E+ A F GS++ Sbjct: 958 CRGHCSSYGKLCRNGGKCRERPIGFFCDCTFSAYTGPFCSNEISAYFGSGSSVIYNFQEN 1017 Query: 708 --------------YFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNG 845 + D K+S E I+ F+T LL VSS+ YK+Y+ + + NG Sbjct: 1018 YLLSKNSSSHAASFHGDMKLS--REMIKFSFRTTRTPSLLLFVSSF-YKEYLSVIIAKNG 1074 Query: 846 GITIEF 863 + I + Sbjct: 1075 SLQIRY 1080
Score = 52.0 bits (123), Expect = 2e-06 Identities = 51/219 (23%), Positives = 85/219 (38%), Gaps = 13/219 (5%) Frame = +3 Query: 45 ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224 +TF + + LP E E F F+T ++L S +L + + +G L+ Sbjct: 372 VTFLSSRSYLALPDFSGEEEVSATFQFRTWNKAGLLLFSELQLISGGILLFLSDG-KLKS 430 Query: 225 TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDPDRPFT--T 395 D WH V + + +D + A P++ ++ T Sbjct: 431 NLYQPGKLPSDITAGVELNDGQWHSVSLSAKKNHLSVAVDGQMASAAPLLGPEQIYSGGT 490 Query: 396 FNFDS--DLLLGSS-QSFTDGYVGCFSNLIVNGVVQDLKSA-------ITDYYGISNGCN 545 + F D GS +S G+ GC + ++G V DL S +D S G + Sbjct: 491 YYFGGCPDKSFGSKCKSPLGGFQGCMRLISISGKVVDLISVQQGSLGNFSDLQIDSCGIS 550 Query: 546 PKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662 +C C + GEC + +S ++C C T YRG C + Sbjct: 551 DRCLPNYCEHGGECSQSWSTFHCNCTNTGYRGATCHNSI 589
Score = 32.0 bits (71), Expect = 2.6 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 7/76 (9%) Frame = +3 Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLL------GSSQSFT 443 D WH V +R K+ +DE+ H+ F N D ++ G S SF Sbjct: 269 DQHWHSVLIQRLGKQVNFTVDEHRHHFHARG---EFNLMNLDYEISFGGIPAPGKSVSFP 325 Query: 444 D-GYVGCFSNLIVNGV 488 + GC NL NGV Sbjct: 326 HRNFHGCLENLYYNGV 341
>sp|Q9BZ76|CNTP3_HUMAN Contactin-associated protein-like 3 precursor (Cell recognition molecule Caspr3) Length = 1288 Score = 126 bits (316), Expect = 1e-28 Identities = 84/304 (27%), Positives = 135/304 (44%), Gaps = 17/304 (5%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPL C GD F N+ +F + ++ P E D+ F FKTTV++ V ++++ + Sbjct: 781 GPLLCRGDQSFWNSASFNTETSYLHFPAFHGELTADVCFFFKTTVSSGVFMENLGITD-- 838 Query: 183 FFEVRIREGFTLRVTF-XXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPV 359 F + +R + +F DN WH VR ERN K + L +D+ P Sbjct: 839 FIRIELRAPTEVTFSFDVGNGPCEVTVQSPTPFNDNQWHHVRAERNVKGASLQVDQ-LPQ 897 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 P +S L +G + + G++GC +L +NGV DL+ T G+ G Sbjct: 898 KMQPAPADGHVRLQLNSQLFIGGTATRQRGFLGCIRSLQLNGVALDLEERATVTPGVEPG 957 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIK---- 701 C C++ C N G C E G C+C + Y G C E+ A F GS++ Sbjct: 958 CAGHCSTYGHLCRNGGRCREKRRGVTCDCAFSAYDGPFCSNEISAYFATGSSMTYHFQEH 1017 Query: 702 ----------LDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNNNGGI 851 + + ++ E I + F+T LL VSS+ Y++Y+ + + NNG + Sbjct: 1018 YTLSENSSSLVSSLHRDVTLTREMITLSFRTTRTPSLLLYVSSF-YEEYLSVILANNGSL 1076 Query: 852 TIEF 863 I + Sbjct: 1077 QIRY 1080
Score = 41.6 bits (96), Expect = 0.003 Identities = 45/220 (20%), Positives = 78/220 (35%), Gaps = 18/220 (8%) Frame = +3 Query: 45 ITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFTLRV 224 +TF + + LP E++ + F F+T +L + F + +++G L++ Sbjct: 372 VTFLSSRSYLALPGNSGEDKVSVTFQFRTWNRAGHLLFGELRRGSGSFVLFLKDG-KLKL 430 Query: 225 TFXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNF 404 + D WH V F +++D++ V +P Sbjct: 431 SLFQPGQSPRNVTAGAGLNDGQWHSVSFSAKWSHMNVVVDDDTAV-------QPLVAVLI 483 Query: 405 DS----------DLLLGSS-QSFTDGYVGCFSNLIVNG-------VVQDLKSAITDYYGI 530 DS D GS +S G+ GC + + V Q + D Sbjct: 484 DSGDTYYFGGCLDNSSGSGCKSPLGGFQGCLRLITIGDKAVDPILVQQGALGSFRDLQID 543 Query: 531 SNGCNPKCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVC 650 S G +C C + GEC + + + C+C T Y G C Sbjct: 544 SCGITDRCLPSYCEHGGECSQSWDTFSCDCLGTGYTGETC 583
>sp|Q5RD64|CNTP2_PONPY Contactin-associated protein-like 2 precursor Length = 1331 Score = 120 bits (301), Expect = 6e-27 Identities = 91/335 (27%), Positives = 145/335 (43%), Gaps = 23/335 (6%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPLRC GD + N +F + ++ E D+ F FKT V L+++ K + Sbjct: 787 GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKED-- 844 Query: 183 FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359 F ++ ++ + +F D+ WH + ERN K++ L +D P Sbjct: 845 FIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRITAERNVKQASLQVDR-LPQ 903 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 + P T S L +G + G++GC +L +NGV DL+ G +G Sbjct: 904 QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISG 962 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDG---------- 683 C+ C S C N G+C E Y GY C+C T Y G C ++VGA F +G Sbjct: 963 CSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022 Query: 684 --------SALEIKLDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNN 839 S +E D + +E I F T LL +SS+ ++ + V Sbjct: 1023 ATNARDSSSRVENAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT-TDFLAVLVKP 1081 Query: 840 NGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938 G + I +++G TR Y + TD+ ++ N Q H++ Sbjct: 1082 TGSLQIRYNLGGTREPYNIDTDH-RNMANGQPHSV 1115
Score = 30.4 bits (67), Expect = 7.5 Identities = 38/218 (17%), Positives = 71/218 (32%), Gaps = 14/218 (6%) Frame = +3 Query: 51 FTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFT-LRVT 227 F + + +P ++ F + F F+T N +++ S N E+ + E + + Sbjct: 377 FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436 Query: 228 FXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPF 389 D WH VRF + L +D + A + P + Sbjct: 437 ITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKY 496 Query: 390 TTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNGCN-------P 548 F + + S + GC + V+ + +L G + Sbjct: 497 FFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIID 556 Query: 549 KCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662 +C C G+C + + + C C T Y G C + Sbjct: 557 RCVPNHCERGGKCSQTWDSFKCTCDETGYTGATCHNSI 594
>sp|Q9UHC6|CNTP2_HUMAN Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2) Length = 1331 Score = 117 bits (294), Expect = 4e-26 Identities = 90/335 (26%), Positives = 144/335 (42%), Gaps = 23/335 (6%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPLRC GD + N +F + ++ E D+ F FKT V L+++ K + Sbjct: 787 GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKED-- 844 Query: 183 FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359 F ++ ++ + +F D+ WH V ERN K++ L +D P Sbjct: 845 FIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDR-LPQ 903 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 + P T S L +G + G++GC +L +NGV DL+ G +G Sbjct: 904 QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFISG 962 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDG---------- 683 C+ C S C N G+C E Y GY C+C T Y G C ++VGA F +G Sbjct: 963 CSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022 Query: 684 --------SALEIKLDYFDQKISTLEEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVNN 839 S ++ D + +E I F T LL +SS+ ++ + V Sbjct: 1023 ATNARDSSSRVDNAPDQQNSHPDLAQEEIRFSFSTTKAPCILLYISSFT-TDFLAVLVKP 1081 Query: 840 NGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938 G + I +++G TR Y + D+ ++ N Q H++ Sbjct: 1082 TGSLQIRYNLGGTREPYNIDVDH-RNMANGQPHSV 1115
Score = 30.8 bits (68), Expect = 5.8 Identities = 38/218 (17%), Positives = 72/218 (33%), Gaps = 14/218 (6%) Frame = +3 Query: 51 FTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQFFEVRIREGFT-LRVT 227 F + + +P ++ F + F F+T N +++ S N E+ + E + + Sbjct: 377 FFNATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHIN 436 Query: 228 FXXXXXXXXXXXXXXXXXDNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPF 389 D WH VRF + L +D + A + P + Sbjct: 437 ITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKY 496 Query: 390 TTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNGCN-------P 548 F + + S + GC + V+ + +L G + Sbjct: 497 FFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVSIDMCAIID 556 Query: 549 KCNSKPCLNRGECYEMYSGYYCECGLTPYRGYVCGREV 662 +C C + G+C + + + C C T Y G C + Sbjct: 557 RCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSI 594
>sp|Q9CPW0|CNTP2_MOUSE Contactin-associated protein-like 2 precursor (Cell recognition molecule Caspr2) Length = 1332 Score = 117 bits (294), Expect = 4e-26 Identities = 92/336 (27%), Positives = 142/336 (42%), Gaps = 24/336 (7%) Frame = +3 Query: 3 GPLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQ 182 GPLRC GD + N +F + ++ E D+ F FKT + V L+++ N Sbjct: 787 GPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLG--NTD 844 Query: 183 FFEVRIREGFTLRVTFXXXXXXXXXXXXXXXXX-DNFWHVVRFERNRKESRLILDENAPV 359 F ++ ++ + +F D+ WH V ERN K++ L +D P Sbjct: 845 FIKLELKSATEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDR-LPQ 903 Query: 360 THSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYGISNG 539 + P T S L +G + G++GC +L +NGV DL+ G +G Sbjct: 904 QIRKAPTEGHTRLELYSQLFVGGAGG-QQGFLGCIRSLRMNGVTLDLEERAKVTSGFKSG 962 Query: 540 CNPKCNS--KPCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFID----------- 680 C+ C S C N G+C E Y GY C+C T Y G C ++VGA F + Sbjct: 963 CSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAP 1022 Query: 681 -------GSALEIKLDYFDQKISTL-EEYIEIGFKTKDKQGTLLQVSSYDYKKYIIIKVN 836 GS E D L +E I F T LL VSS ++ + V Sbjct: 1023 AVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSSLT-TDFLAVLVK 1081 Query: 837 NNGGITIEFDVGFTR--YEVTTDYIVDLCNDQHHTL 938 G + I +++G TR + + D+ ++ N Q H++ Sbjct: 1082 PTGNLQIRYNLGGTREPFNIDVDH-RNMANGQPHSV 1116
Score = 30.8 bits (68), Expect = 5.8 Identities = 29/144 (20%), Positives = 50/144 (34%), Gaps = 17/144 (11%) Frame = +3 Query: 282 DNFWHVVRFERNRKESRLILD-ENAPVTHSEDP-----DRPFTTFNFDSDLLLGSSQSFT 443 D WH VRF + L +D + A + P + F + + S + Sbjct: 455 DGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNHMNNASYSALQ 514 Query: 444 DGYVGCFSNLIVNGVVQDL-----------KSAITDYYGISNGCNPKCNSKPCLNRGECY 590 + GC + V+ + +L + D I + C P C + G+C Sbjct: 515 PSFQGCMQLIQVDDQLVNLYEVAQRKPGSFANVTIDMCAIIDRCVPN----HCEHGGKCS 570 Query: 591 EMYSGYYCECGLTPYRGYVCGREV 662 + + + C C T Y G C + Sbjct: 571 QTWDSFKCTCDETGYSGATCHNSI 594
>sp|P97846|CNTP1_RAT Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190) (Paranodin) Length = 1381 Score = 102 bits (254), Expect = 2e-21 Identities = 71/244 (29%), Positives = 109/244 (44%), Gaps = 11/244 (4%) Frame = +3 Query: 6 PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185 PLRC GD NTI+F + A + PP+ A + D+ F F+T+ + V L++ + G F Sbjct: 776 PLRCYGDRNSWNTISF-RTGAALRFPPIRANHSLDVSFYFRTSAPSGVFLEN---MGGPF 831 Query: 186 FE-----VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLI 338 + VR+ + V F D+ WH+VR E N K++RL Sbjct: 832 CQWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLR 891 Query: 339 LDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITD 518 +D P P + + +D L +GS++ +VGC + +NGV +L+ Sbjct: 892 VDHR-PWVLRPMPLQTYIWLEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA 950 Query: 519 YYGISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSAL 692 G C C PC + G C E YS Y C+C LT + G C ++G F G+ + Sbjct: 951 SEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWM 1010 Query: 693 EIKL 704 L Sbjct: 1011 RYNL 1014
Score = 43.9 bits (102), Expect = 7e-04 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%) Frame = +3 Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440 D FWH V F + EN V +D + ++ + G+S F Sbjct: 442 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 492 Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563 + GC L V+G + +L + D GI++ C+P Sbjct: 493 SRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNM--- 549 Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650 C + G CY+ + + C C LT Y+G C Sbjct: 550 -CEHDGRCYQSWDDFICYCELTGYKGVTC 577
>sp|P78357|CNTP1_HUMAN Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (p190) Length = 1384 Score = 102 bits (253), Expect = 2e-21 Identities = 71/241 (29%), Positives = 108/241 (44%), Gaps = 8/241 (3%) Frame = +3 Query: 6 PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185 PLRC GD NTI+F A + PP+ A + D+ F F+T+ + V L+++ Q+ Sbjct: 775 PLRCYGDRNSWNTISFHT-GAALRFPPIRANHSLDVSFYFRTSAPSGVFLENMGGPYCQW 833 Query: 186 FE--VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLILDE 347 VR+ + V F D+ WH+VR E N K++RL +D Sbjct: 834 RRPYVRVELNTSRDVVFAFDVGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLRVDH 893 Query: 348 NAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITDYYG 527 P P + + +D L +GS++ +VGC + +NGV +L+ G Sbjct: 894 R-PWVLRPMPLQTYIWMEYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANASEG 952 Query: 528 ISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSALEIK 701 S C C PC + G C E YS Y C+C LT + G C ++G F G+ + Sbjct: 953 TSPNCTGHCAHPRLPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFEPGTWMRYN 1012 Query: 702 L 704 L Sbjct: 1013 L 1013
Score = 43.5 bits (101), Expect = 9e-04 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%) Frame = +3 Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440 D FWH V F + EN V +D + ++ + G+S F Sbjct: 441 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 491 Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563 + GC L V+G + +L + D GI++ C+P Sbjct: 492 SRWDCHSNQTAFHGCMELLKVDGQLVNLTLVEGRRLGFYAEVLFDTCGITDRCSPNM--- 548 Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650 C + G CY+ + + C C LT Y+G C Sbjct: 549 -CEHDGRCYQSWDDFICYCELTGYKGETC 576
>sp|O54991|CNTP1_MOUSE Contactin-associated protein 1 precursor (Caspr) (Caspr1) (Neurexin 4) (Neurexin IV) (Paranodin) (NCP1) (MHDNIV) Length = 1385 Score = 99.4 bits (246), Expect = 1e-20 Identities = 71/244 (29%), Positives = 107/244 (43%), Gaps = 11/244 (4%) Frame = +3 Query: 6 PLRCTGDSLFDNTITFTKHDAVINLPPLFAENEFDMIFLFKTTVANAVILQSVSKLNGQF 185 PLRC GD NTI+F A + PP+ A + D+ F F+T+ + V L++ + G F Sbjct: 776 PLRCYGDRNSWNTISFHT-GAALRFPPIRANHSLDVSFYFRTSAPSGVFLEN---MGGPF 831 Query: 186 FE-----VRIREGFTLRVTFXXXXXXXXXXXXXXXXX----DNFWHVVRFERNRKESRLI 338 VR+ + V F D+ WH+VR E N K++RL Sbjct: 832 CRWRRPYVRVELNTSRDVVFAFDIGNGDENLTVHSDDFEFNDDEWHLVRAEINVKQARLR 891 Query: 339 LDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSFTDGYVGCFSNLIVNGVVQDLKSAITD 518 +D P P + + +D L +GS++ +VGC + +NGV +L+ Sbjct: 892 VDHR-PWVLRPMPLQTYIWLVYDQPLYVGSAELKRRPFVGCLRAMRLNGVTLNLEGRANA 950 Query: 519 YYGISNGCNPKCNSK--PCLNRGECYEMYSGYYCECGLTPYRGYVCGREVGASFIDGSAL 692 G C C PC + G C E YS Y C+C LT + G C ++G F G+ + Sbjct: 951 SEGTFPNCTGHCTHPRFPCFHGGRCVERYSYYTCDCDLTAFDGPYCNHDIGGFFETGTWM 1010 Query: 693 EIKL 704 L Sbjct: 1011 RYNL 1014
Score = 43.9 bits (102), Expect = 7e-04 Identities = 35/149 (23%), Positives = 55/149 (36%), Gaps = 26/149 (17%) Frame = +3 Query: 282 DNFWHVVRFERNRKESRLILDENAPVTHSEDPDRPFTTFNFDSDLLLGSSQSF------- 440 D FWH V F + EN V +D + ++ + G+S F Sbjct: 442 DGFWHEVNF---------VAQENHAVISIDDVEGAEVRVSYPLLIRTGTSYFFGGCPKPA 492 Query: 441 --------TDGYVGCFSNLIVNGVVQDLK-----------SAITDYYGISNGCNPKCNSK 563 + GC L V+G + +L + D GI++ C+P Sbjct: 493 SRWGCHSNQTAFHGCMELLKVDGQLVNLTLVEFRKLGYFAEVLFDTCGITDRCSPNM--- 549 Query: 564 PCLNRGECYEMYSGYYCECGLTPYRGYVC 650 C + G CY+ + + C C LT Y+G C Sbjct: 550 -CEHDGRCYQSWDDFICYCELTGYKGVTC 577
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 100,770,340 Number of Sequences: 369166 Number of extensions: 1984715 Number of successful extensions: 6368 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5076 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6263 length of database: 68,354,980 effective HSP length: 110 effective length of database: 48,034,130 effective search space used: 9702894260 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)