Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00142 (672 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9Z319|CORIN_MOUSE Atrial natriuteric peptide-converting... 48 3e-05 sp|Q9Y5Q5|CORIN_HUMAN Atrial natriuteric peptide-converting... 45 1e-04 sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related... 45 2e-04 sp|P98074|ENTK_PIG Enteropeptidase precursor (Enterokinase)... 42 0.001 sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-relate... 41 0.003 sp|P97435|ENTK_MOUSE Enteropeptidase (Enterokinase) [Contai... 41 0.003 sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-relat... 40 0.006 sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-rela... 40 0.007 sp|P35950|LDLR_CRIGR Low-density lipoprotein receptor precu... 39 0.009 sp|P18208|GLBM_TYLHE Giant extracellular hemoglobin linker ... 39 0.016
>sp|Q9Z319|CORIN_MOUSE Atrial natriuteric peptide-converting enzyme (pro-ANP-converting enzyme) (Corin) (Low density lipoprotein receptor-related protein 4) Length = 1113 Score = 47.8 bits (112), Expect = 3e-05 Identities = 19/35 (54%), Positives = 21/35 (60%) Frame = +1 Query: 103 GCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 GC ERA W C +CL ICDG PDCP+ DE Sbjct: 683 GCKERALWECPFNKQCLKHTLICDGFPDCPDSMDE 717
Score = 33.9 bits (76), Expect = 0.40 Identities = 11/27 (40%), Positives = 19/27 (70%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G+C++ +++CDG+ DC +K DE C Sbjct: 421 GRCIAAEWVCDGDHDCVDKSDEVNCSC 447
Score = 32.3 bits (72), Expect = 1.1 Identities = 12/27 (44%), Positives = 15/27 (55%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 GKCL + +CDG DC + DE C Sbjct: 384 GKCLHYSLLCDGYDDCGDPSDEQNCDC 410
Score = 30.8 bits (68), Expect = 3.3 Identities = 11/25 (44%), Positives = 16/25 (64%) Frame = +1 Query: 136 TPGKCLSFDFICDGEPDCPEKYDED 210 T G+C+ F CDG+ DC + DE+ Sbjct: 456 TSGQCIPSTFQCDGDEDCKDGSDEE 480
>sp|Q9Y5Q5|CORIN_HUMAN Atrial natriuteric peptide-converting enzyme (pro-ANP-converting enzyme) (Corin) (Heart-specific serine proteinase ATC2) (Transmembrane protease, serine 10) Length = 1042 Score = 45.4 bits (106), Expect = 1e-04 Identities = 18/35 (51%), Positives = 21/35 (60%) Frame = +1 Query: 103 GCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 GC ER W C + +CL ICDG PDCP+ DE Sbjct: 615 GCKERDLWECPSNKQCLKHTVICDGFPDCPDYMDE 649
Score = 34.7 bits (78), Expect = 0.23 Identities = 11/27 (40%), Positives = 19/27 (70%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G+C++ +++CDG+ DC +K DE C Sbjct: 353 GRCIAMEWVCDGDHDCVDKSDEVNCSC 379
Score = 33.9 bits (76), Expect = 0.40 Identities = 18/53 (33%), Positives = 26/53 (49%) Frame = +1 Query: 64 FNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 +N + +A C E + C T GKCL++ +CDG DC + DE C Sbjct: 292 YNDCDDWSDEAHCNCSENL-FHCHT-GKCLNYSLVCDGYDDCGDLSDEQNCDC 342
Score = 29.3 bits (64), Expect = 9.7 Identities = 10/23 (43%), Positives = 15/23 (65%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDED 210 G+C+ F CDG+ DC + DE+ Sbjct: 390 GQCIPSTFQCDGDEDCKDGSDEE 412
Score = 29.3 bits (64), Expect = 9.7 Identities = 11/20 (55%), Positives = 13/20 (65%) Frame = +1 Query: 148 CLSFDFICDGEPDCPEKYDE 207 C+S D CDGE DC + DE Sbjct: 667 CVSRDLWCDGEADCSDSSDE 686
>sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330) Length = 4660 Score = 44.7 bits (104), Expect = 2e-04 Identities = 16/29 (55%), Positives = 20/29 (68%) Frame = +1 Query: 124 WPCKTPGKCLSFDFICDGEPDCPEKYDED 210 W C G+C+S D +CDG PDCPE DE+ Sbjct: 270 WACPGSGRCISIDKVCDGVPDCPEGDDEN 298
Score = 41.2 bits (95), Expect = 0.002 Identities = 21/68 (30%), Positives = 31/68 (45%), Gaps = 7/68 (10%) Frame = +1 Query: 61 CFNIFEKRESKAGNGCPERAP-------WPCKTPGKCLSFDFICDGEPDCPEKYDEDAAL 219 C +++ R++ GCP R P + C+ G C+ + CDG PDC DE Sbjct: 1208 CDGVYDCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDEHTG- 1266 Query: 220 CIAKDRPP 243 C+ K P Sbjct: 1267 CVPKTCSP 1274
Score = 33.5 bits (75), Expect = 0.52 Identities = 11/23 (47%), Positives = 18/23 (78%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDED 210 G+C+S +++CDG+ DC + DED Sbjct: 2918 GRCISGNWVCDGDNDCGDMSDED 2940
Score = 33.5 bits (75), Expect = 0.52 Identities = 18/42 (42%), Positives = 23/42 (54%) Frame = +1 Query: 97 GNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 G CP A + CK C+ +ICDGE DC + DE+ LC Sbjct: 3841 GTYCPA-AMFECKNH-VCIQSFWICDGENDCVDGSDEEIHLC 3880
Score = 32.7 bits (73), Expect = 0.88 Identities = 10/23 (43%), Positives = 18/23 (78%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDED 210 G+C++ +++CDG+ DC + DED Sbjct: 232 GQCINQNWVCDGDDDCQDSGDED 254
Score = 32.7 bits (73), Expect = 0.88 Identities = 12/31 (38%), Positives = 18/31 (58%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 C+T C+ F+CDG+ DC + DE+ C Sbjct: 2830 CQTTNICVPRAFLCDGDNDCGDGSDENPIYC 2860
Score = 32.3 bits (72), Expect = 1.1 Identities = 15/39 (38%), Positives = 19/39 (48%) Frame = +1 Query: 106 CPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 CP W C C++ +CDG DCP DE + LC Sbjct: 1313 CPS-TQWQCPGYSTCINLSALCDGVFDCPNGTDE-SPLC 1349
Score = 31.2 bits (69), Expect = 2.6 Identities = 18/52 (34%), Positives = 23/52 (44%), Gaps = 9/52 (17%) Frame = +1 Query: 79 KRESKAGNGCPERAP---------WPCKTPGKCLSFDFICDGEPDCPEKYDE 207 +R+ G P R P +PC GKC+ F CDG DC + DE Sbjct: 1006 QRDQMTCEGDPAREPPTQQCGSLSFPCNN-GKCVPSFFRCDGVDDCHDNSDE 1056
Score = 31.2 bits (69), Expect = 2.6 Identities = 11/26 (42%), Positives = 16/26 (61%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDE 207 C +P +C+ + CDGE DC + DE Sbjct: 2872 CLSPQRCIPSYWFCDGEADCADGSDE 2897
Score = 30.8 bits (68), Expect = 3.3 Identities = 13/39 (33%), Positives = 20/39 (51%), Gaps = 4/39 (10%) Frame = +1 Query: 103 GCPERAP----WPCKTPGKCLSFDFICDGEPDCPEKYDE 207 GCP R+ + C G C+ ++CD + DC + DE Sbjct: 61 GCPPRSCESGLFLCPAEGTCIPSSWVCDEDKDCSDGADE 99
Score = 30.4 bits (67), Expect = 4.4 Identities = 14/41 (34%), Positives = 21/41 (51%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALCIAKDRPPAVIMEQF 264 G+C+ F+CD + DC + DE LC + P + QF Sbjct: 3044 GRCIPRFFVCDEDNDCGDGSDEQEHLCHTPE--PTCPLHQF 3082
Score = 30.4 bits (67), Expect = 4.4 Identities = 15/43 (34%), Positives = 20/43 (46%), Gaps = 4/43 (9%) Frame = +1 Query: 106 CPER----APWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 CP R + C+ G C S +C+ DC + DED LC Sbjct: 3550 CPHRFCRLGQFQCRD-GNCTSPQALCNARQDCADGSDEDRVLC 3591
Score = 29.6 bits (65), Expect = 7.5 Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Frame = +1 Query: 43 YLYSSECFNIFEKRESKAG---NGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDA 213 Y Y + +N +AG C + C G+C+ ++C+G +C + D Sbjct: 2757 YHYRCDYYNDCGDNSDEAGCLFRNCNSTTEFTCSN-GRCIPLSYVCNGINNCHDNDTSDE 2815 Query: 214 ALCIAKDRPP 243 C PP Sbjct: 2816 KNCPPHTCPP 2825
Score = 29.6 bits (65), Expect = 7.5 Identities = 12/38 (31%), Positives = 18/38 (47%) Frame = +1 Query: 94 AGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 A C + CKT +C+ +C+G DC + DE Sbjct: 3676 AAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDE 3713
Score = 29.3 bits (64), Expect = 9.7 Identities = 14/50 (28%), Positives = 27/50 (54%) Frame = +1 Query: 58 ECFNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 +C + +++++ AG C + C G+C+ ++ CD DCP+ DE Sbjct: 92 DCSDGADEQQNCAGTTCSAQQ-MTCSN-GQCIPSEYRCDHVSDCPDGSDE 139
>sp|P98074|ENTK_PIG Enteropeptidase precursor (Enterokinase) [Contains: Enteropeptidase non-catalytic mini chain; Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] Length = 1034 Score = 42.0 bits (97), Expect = 0.001 Identities = 15/32 (46%), Positives = 21/32 (65%) Frame = +1 Query: 127 PCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 PC KC++ D CDGE +CP+ DED+ +C Sbjct: 205 PCADALKCIAVDLFCDGELNCPDGSDEDSKIC 236
>sp|Q04833|LRP_CAEEL Low-density lipoprotein receptor-related protein precursor (LRP) Length = 4753 Score = 40.8 bits (94), Expect = 0.003 Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 2/41 (4%) Frame = +1 Query: 121 PW--PCKTPGKCLSFDFICDGEPDCPEKYDEDAALCIAKDR 237 PW C G+C+ F CDG+ DC ++ DE LC++ +R Sbjct: 3711 PWMFKCAATGRCIPRRFTCDGDDDCGDRSDEADTLCMSAER 3751
Score = 37.7 bits (86), Expect = 0.027 Identities = 17/45 (37%), Positives = 23/45 (51%) Frame = +1 Query: 106 CPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALCIAKDRP 240 C + + C T GKC+ ++CD E DC + DE A C RP Sbjct: 3833 CDDVGEFRCATSGKCIPRRWMCDTENDCGDNSDELDASCGGTTRP 3877
Score = 34.7 bits (78), Expect = 0.23 Identities = 13/37 (35%), Positives = 19/37 (51%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDEDAALCIAKDRP 240 C+ KC+ + CDG+ DC + DED C +P Sbjct: 1108 CRNTKKCIPAQYGCDGDNDCGDYSDEDVKYCKDGQKP 1144
Score = 33.5 bits (75), Expect = 0.52 Identities = 15/56 (26%), Positives = 28/56 (50%) Frame = +1 Query: 55 SECFNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 ++C + +++ GN + C G+C+ ++CDG+ DC + DED C Sbjct: 1169 NDCGDGSDEKLEMCGNATCAANQFSCAN-GRCIPIYWLCDGDNDCYDGTDEDKERC 1223
Score = 32.3 bits (72), Expect = 1.1 Identities = 13/21 (61%), Positives = 15/21 (71%) Frame = +1 Query: 145 KCLSFDFICDGEPDCPEKYDE 207 KC+S FICDGE DC + DE Sbjct: 3018 KCISRAFICDGEDDCGDGSDE 3038
Score = 30.4 bits (67), Expect = 4.4 Identities = 13/34 (38%), Positives = 16/34 (47%) Frame = +1 Query: 106 CPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 CP W C G C+ +CDG DC + DE Sbjct: 262 CPP-GKWNCPGTGHCIDQLKLCDGSKDCADGADE 294
Score = 30.4 bits (67), Expect = 4.4 Identities = 11/33 (33%), Positives = 16/33 (48%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALCIAKDRP 240 G C+ CD +PDC + DE+ C + P Sbjct: 2803 GSCILLGATCDSKPDCADASDENPNYCNTRSCP 2835
Score = 29.6 bits (65), Expect = 7.5 Identities = 12/26 (46%), Positives = 18/26 (69%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDE 207 CK G+C+ ++ CDGE DC ++ DE Sbjct: 1063 CKN-GRCIPKEWKCDGENDCLDESDE 1087
Score = 29.6 bits (65), Expect = 7.5 Identities = 10/24 (41%), Positives = 17/24 (70%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDA 213 G+C+ +++CDGE DC + DE + Sbjct: 1323 GRCILNNWLCDGENDCGDGSDESS 1346
Score = 29.6 bits (65), Expect = 7.5 Identities = 10/25 (40%), Positives = 16/25 (64%) Frame = +1 Query: 148 CLSFDFICDGEPDCPEKYDEDAALC 222 C+ F+CDG+ DC + DE ++ C Sbjct: 3971 CIPRKFMCDGDNDCGDNSDETSSEC 3995
Score = 29.3 bits (64), Expect = 9.7 Identities = 11/32 (34%), Positives = 16/32 (50%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDEDAALCI 225 C C+ +CDG DC +K DE+ C+ Sbjct: 2926 CPNTNICIQPADLCDGYDDCGDKADENQLFCM 2957
>sp|P97435|ENTK_MOUSE Enteropeptidase (Enterokinase) [Contains: Enteropeptidase non-catalytic heavy chain; Enteropeptidase catalytic light chain] Length = 1069 Score = 40.8 bits (94), Expect = 0.003 Identities = 15/32 (46%), Positives = 19/32 (59%) Frame = +1 Query: 127 PCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 PC C++ D CDGE +CP+ DED LC Sbjct: 235 PCAHAWNCVATDLFCDGEVNCPDGSDEDTGLC 266
>sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 precursor (Megalin) (Glycoprotein 330) (gp330) Length = 4655 Score = 40.0 bits (92), Expect = 0.006 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 7/70 (10%) Frame = +1 Query: 52 SSECFNIFEKRESKAGNGCPERAP-------WPCKTPGKCLSFDFICDGEPDCPEKYDED 210 ++ C +F+ ++ GCP R P + C+ G C+ + CDG PDC DE Sbjct: 1204 TNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEH 1263 Query: 211 AALCIAKDRP 240 A C+ K P Sbjct: 1264 NA-CVPKTCP 1272
Score = 36.6 bits (83), Expect = 0.061 Identities = 13/29 (44%), Positives = 18/29 (62%) Frame = +1 Query: 124 WPCKTPGKCLSFDFICDGEPDCPEKYDED 210 W C G+C+S +CDG DCP + DE+ Sbjct: 271 WSCPESGRCISIYKVCDGILDCPGREDEN 299
Score = 33.9 bits (76), Expect = 0.40 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 13/47 (27%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAA-------------LCIAKDRPP 243 G+C+ ++ICDG+ DC + DED LC+ DRPP Sbjct: 2916 GRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCV-NDRPP 2961
Score = 33.1 bits (74), Expect = 0.67 Identities = 11/23 (47%), Positives = 17/23 (73%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDED 210 G+C+ +++CDGE DC + DED Sbjct: 232 GRCIYQNWVCDGEDDCKDNGDED 254
Score = 32.0 bits (71), Expect = 1.5 Identities = 17/55 (30%), Positives = 26/55 (47%), Gaps = 5/55 (9%) Frame = +1 Query: 61 CFNIFEKRESKAGNGCPERAPWP-----CKTPGKCLSFDFICDGEPDCPEKYDED 210 C + + R++ GC ER P CK C+ + CDG+ DC + DE+ Sbjct: 3699 CNGVDDCRDNSDEQGCEERTCHPVGDFRCKNH-HCIPLRWQCDGQNDCGDNSDEE 3752
Score = 31.6 bits (70), Expect = 2.0 Identities = 15/43 (34%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Frame = +1 Query: 106 CPER----APWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 CP+R + C + G C S +C+ +CP+ DED LC Sbjct: 3548 CPQRFCRLGQFQC-SDGNCTSPQTLCNAHQNCPDGSDEDRLLC 3589
Score = 31.2 bits (69), Expect = 2.6 Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 3/41 (7%) Frame = +1 Query: 109 PERAP---WPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 P R P W C C++ +CDG DCP DE + LC Sbjct: 1309 PFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE-SPLC 1348
Score = 31.2 bits (69), Expect = 2.6 Identities = 12/27 (44%), Positives = 17/27 (62%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G+C+S F+CD + DC + DE LC Sbjct: 3042 GRCISKTFVCDEDNDCGDGSDELMHLC 3068
Score = 30.8 bits (68), Expect = 3.3 Identities = 12/28 (42%), Positives = 18/28 (64%) Frame = +1 Query: 124 WPCKTPGKCLSFDFICDGEPDCPEKYDE 207 +PCK G+C+ ++CDG DC + DE Sbjct: 1031 FPCKN-GRCVPNYYLCDGVDDCHDNSDE 1057
Score = 30.8 bits (68), Expect = 3.3 Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 4/43 (9%) Frame = +1 Query: 106 CPERAPWP----CKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 CP+R C C+ ++CDG+ DC + DE+ C Sbjct: 2817 CPDRTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYC 2859
Score = 30.4 bits (67), Expect = 4.4 Identities = 9/22 (40%), Positives = 16/22 (72%) Frame = +1 Query: 145 KCLSFDFICDGEPDCPEKYDED 210 +C+ ++CDG+ DC + YDE+ Sbjct: 2964 RCIPQSWVCDGDVDCTDGYDEN 2985
Score = 30.0 bits (66), Expect = 5.7 Identities = 9/26 (34%), Positives = 17/26 (65%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDE 207 C++ G+C+ ++CD + DC + DE Sbjct: 74 CQSEGQCIPSSWVCDQDQDCDDGSDE 99
Score = 30.0 bits (66), Expect = 5.7 Identities = 9/21 (42%), Positives = 14/21 (66%) Frame = +1 Query: 145 KCLSFDFICDGEPDCPEKYDE 207 +C+ F+CDG+ DC + DE Sbjct: 1160 RCIDLSFVCDGDKDCVDGSDE 1180
Score = 29.3 bits (64), Expect = 9.7 Identities = 10/27 (37%), Positives = 18/27 (66%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G+C+S ++ CD + DC + DE ++C Sbjct: 2710 GRCISEEWKCDNDNDCGDGSDEMESVC 2736
>sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-related protein 1B precursor (Low-density lipoprotein receptor-related protein-deleted in tumor) (LRP-DIT) Length = 4599 Score = 39.7 bits (91), Expect = 0.007 Identities = 17/53 (32%), Positives = 31/53 (58%), Gaps = 7/53 (13%) Frame = +1 Query: 85 ESKAGNG----CPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE---DAALC 222 + K NG C + + C++ G+C++ ++CDG+ DC ++ DE D+ LC Sbjct: 1084 DEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEEDCDSFLC 1136
Score = 37.0 bits (84), Expect = 0.047 Identities = 13/31 (41%), Positives = 19/31 (61%) Frame = +1 Query: 130 CKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 C C+S ++CDG+PDCP++ DE C Sbjct: 39 CHDHVTCVSQSWLCDGDPDCPDQSDESLDTC 69
Score = 35.8 bits (81), Expect = 0.10 Identities = 13/26 (50%), Positives = 18/26 (69%) Frame = +1 Query: 145 KCLSFDFICDGEPDCPEKYDEDAALC 222 KC+S +ICDGE DC + DE ++C Sbjct: 2731 KCISKHWICDGEDDCGDSLDESDSIC 2756
Score = 35.8 bits (81), Expect = 0.10 Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 4/38 (10%) Frame = +1 Query: 106 CPERAPWP----CKTPGKCLSFDFICDGEPDCPEKYDE 207 CPE + P CKT C+S ++CD +PDC + DE Sbjct: 3431 CPENSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDE 3468
Score = 34.7 bits (78), Expect = 0.23 Identities = 13/35 (37%), Positives = 19/35 (54%) Frame = +1 Query: 106 CPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDED 210 CP P+ C+ CL + IC+G DC + DE+ Sbjct: 3715 CPPTRPYRCRNDRICLQLEKICNGINDCGDNSDEE 3749
Score = 32.3 bits (72), Expect = 1.1 Identities = 17/53 (32%), Positives = 26/53 (49%) Frame = +1 Query: 49 YSSECFNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 +S E K E+++ GC + C+ G C+ + CDGE DC + DE Sbjct: 1034 FSDETHINCTKEEARSPAGCIGNE-FQCRPDGNCIPDLWRCDGEKDCEDGSDE 1085
Score = 32.3 bits (72), Expect = 1.1 Identities = 21/48 (43%), Positives = 24/48 (50%), Gaps = 7/48 (14%) Frame = +1 Query: 106 CPERAPWP----CKTPGKCLSFDFICDGEPDCPEKYDE---DAALCIA 228 CPE P C T G C FICDGE DC + DE D +C+A Sbjct: 3352 CPEFKCQPGRFQCGT-GLCALPAFICDGENDCGDNSDELNCDTHVCLA 3398
Score = 32.0 bits (71), Expect = 1.5 Identities = 19/51 (37%), Positives = 25/51 (49%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALCIAKDRPPAVIMEQFITKWKDWFIP 294 G CLS C+GEPDC + DE + K+ +QF K K + IP Sbjct: 3604 GGCLSASLKCNGEPDCVDGSDEMDCVIECKE-------DQFQCKNKAYCIP 3647
Score = 31.6 bits (70), Expect = 2.0 Identities = 14/50 (28%), Positives = 25/50 (50%) Frame = +1 Query: 58 ECFNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 +C + ++ +S G + C+ C+ ++CDGE DCP+ DE Sbjct: 2744 DCGDSLDESDSICGAVTCAADMFSCQGSHACVPQHWLCDGERDCPDGSDE 2793
Score = 30.4 bits (67), Expect = 4.4 Identities = 11/27 (40%), Positives = 14/27 (51%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G C+ + CDG P C +K DE C Sbjct: 2521 GDCVDYVLTCDGIPHCKDKSDEKLLYC 2547
Score = 30.4 bits (67), Expect = 4.4 Identities = 14/27 (51%), Positives = 16/27 (59%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALC 222 G+CLS + CDG DC KY ED C Sbjct: 3563 GQCLSAKWKCDGHEDC--KYGEDEKNC 3587
Score = 30.0 bits (66), Expect = 5.7 Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDE-DAALCIAKDRPPAVIMEQFITKWK 279 G C+S F CDGE DC + DE + +KD+ + KWK Sbjct: 3525 GDCVSSRFWCDGEFDCADGSDEKNCETSCSKDQFQCSNGQCLSAKWK 3571
Score = 30.0 bits (66), Expect = 5.7 Identities = 12/32 (37%), Positives = 17/32 (53%) Frame = +1 Query: 148 CLSFDFICDGEPDCPEKYDEDAALCIAKDRPP 243 C ++CDGE DC + DE +C+ PP Sbjct: 3686 CKLHFWVCDGEDDCGDNSDEAPDMCVKFLCPP 3717
Score = 29.6 bits (65), Expect = 7.5 Identities = 15/44 (34%), Positives = 24/44 (54%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDEDAALCIAKDRPPAVIMEQFITK 273 G+C+ ++CD E DC ++ DE A+ + P + QFI K Sbjct: 937 GRCIPTAWLCDREDDCGDQTDEVASC----EFPTCEPLTQFICK 976
Score = 29.6 bits (65), Expect = 7.5 Identities = 12/35 (34%), Positives = 18/35 (51%) Frame = +1 Query: 103 GCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDE 207 GCP G+C+ ++CDG+ DC + DE Sbjct: 2688 GCPS---------GRCILNTWVCDGQKDCEDGLDE 2713
Score = 29.3 bits (64), Expect = 9.7 Identities = 11/31 (35%), Positives = 16/31 (51%) Frame = +1 Query: 148 CLSFDFICDGEPDCPEKYDEDAALCIAKDRP 240 C+ + CDG+ DC + DED+ C P Sbjct: 857 CIQARWKCDGDDDCLDGSDEDSVTCFNHSCP 887
>sp|P35950|LDLR_CRIGR Low-density lipoprotein receptor precursor (LDL receptor) Length = 854 Score = 39.3 bits (90), Expect = 0.009 Identities = 14/39 (35%), Positives = 26/39 (66%) Frame = +1 Query: 112 ERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALCIA 228 +R + C+ GKC++ ++CDG P+CP+ DE + C++ Sbjct: 28 DRNEFRCRD-GKCIASKWVCDGSPECPDGSDESSETCMS 65
Score = 31.2 bits (69), Expect = 2.6 Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 3/30 (10%) Frame = +1 Query: 142 GKCLSFDFICDGEPDCPEKYDE---DAALC 222 GKC+S F+CD + DC + DE AA C Sbjct: 119 GKCISQKFVCDQDQDCVDGSDEAHCQAATC 148
Score = 29.3 bits (64), Expect = 9.7 Identities = 9/22 (40%), Positives = 15/22 (68%) Frame = +1 Query: 145 KCLSFDFICDGEPDCPEKYDED 210 +C+ ++CDG DC +K DE+ Sbjct: 209 ECIHRSWVCDGSADCKDKSDEE 230
>sp|P18208|GLBM_TYLHE Giant extracellular hemoglobin linker 2 chain Length = 236 Score = 38.5 bits (88), Expect = 0.016 Identities = 20/58 (34%), Positives = 28/58 (48%) Frame = +1 Query: 49 YSSECFNIFEKRESKAGNGCPERAPWPCKTPGKCLSFDFICDGEPDCPEKYDEDAALC 222 Y SE + + + GNGC R + +C+S CDG PDC DED+ +C Sbjct: 49 YKSEFRELEFRVDELEGNGCEPRHFQCGGSAMECISDLLTCDGSPDCANGADEDSDVC 106
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 75,221,532 Number of Sequences: 369166 Number of extensions: 1519379 Number of successful extensions: 4854 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4244 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4849 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 5636246860 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)