Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00140 (709 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceo... 343 3e-94 sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceo... 342 4e-94 sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceo... 342 6e-94 sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10 272 7e-73 sp|P49955|S3B1_YEAST U2 snRNP component HSH155 241 1e-63 sp|O84075|Y072_CHLTR Hypothetical zinc metalloprotease CT072 33 0.74 sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Si... 32 1.7 sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Si... 32 1.7 sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Si... 32 1.7 sp|Q6FDP8|UPPP2_ACIAD Undecaprenyl-diphosphatase 2 (Undecap... 32 2.2
>sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceosome associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155 kDa subunit) Length = 1304 Score = 343 bits (880), Expect = 3e-94 Identities = 164/221 (74%), Positives = 191/221 (86%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181 IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV Sbjct: 1084 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1143 Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361 QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G Sbjct: 1144 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1203 Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPARKITD 541 CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL HPARK+ D Sbjct: 1204 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRD 1263 Query: 542 MMCKIYNALYIANQDGLVSGFPRIKNDNRNQYLRYELQYKL 664 + KIYN++YI +QD L++ +PRI ND++N Y+RYEL Y L Sbjct: 1264 VYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL 1304
>sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceosome associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155 kDa subunit) (146 kDa nuclear protein) Length = 1307 Score = 342 bits (878), Expect = 4e-94 Identities = 163/221 (73%), Positives = 190/221 (85%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181 IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV Sbjct: 1087 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1146 Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361 QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G Sbjct: 1147 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1206 Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPARKITD 541 CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G ++ Y LQGL HPARK+ D Sbjct: 1207 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMVQYCLQGLFHPARKVRD 1266 Query: 542 MMCKIYNALYIANQDGLVSGFPRIKNDNRNQYLRYELQYKL 664 + KIYN++YI +QD L++ +PRI ND +N Y+RYEL Y L Sbjct: 1267 VYWKIYNSIYIGSQDALIAHYPRIYNDEKNTYIRYELDYTL 1307
>sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceosome associated protein 155) (SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155 kDa subunit) Length = 1304 Score = 342 bits (877), Expect = 6e-94 Identities = 163/221 (73%), Positives = 191/221 (86%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181 IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV Sbjct: 1084 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1143 Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361 QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G Sbjct: 1144 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1203 Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPARKITD 541 CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL HPARK+ D Sbjct: 1204 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRD 1263 Query: 542 MMCKIYNALYIANQDGLVSGFPRIKNDNRNQYLRYELQYKL 664 + KIYN++YI +QD L++ +PRI ND++N Y+RY+L Y L Sbjct: 1264 VYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYDLDYIL 1304
>sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10 Length = 1188 Score = 272 bits (695), Expect = 7e-73 Identities = 125/212 (58%), Positives = 164/212 (77%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181 I+KA+GP DVLATLLNNLKVQERQNRVCTTVAIAIVAETC PFTV+P LM ++R P++NV Sbjct: 968 ISKAIGPQDVLATLLNNLKVQERQNRVCTTVAIAIVAETCMPFTVVPALMADYRTPEMNV 1027 Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361 QNGVLKSL+FMFEYIGE A+DY+YA+ PLL DAL+DRD VHRQTA S + H++LG G G Sbjct: 1028 QNGVLKSLAFMFEYIGEQARDYVYAITPLLADALMDRDAVHRQTAASVIKHLSLGCVGLG 1087 Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPARKITD 541 EDA++HLLN +WPN+LE SPH++ A + ++ +R G ++ Y++QGL HP+RK+ + Sbjct: 1088 VEDAMIHLLNILWPNILEESPHVINAVREGIDGIRNCIGVGPIMAYLVQGLFHPSRKVRN 1147 Query: 542 MMCKIYNALYIANQDGLVSGFPRIKNDNRNQY 637 YN+ Y+ + D +V +P + +D N Y Sbjct: 1148 TYWTSYNSAYVQSADAMVPYYPHVDDDQFNNY 1179
>sp|P49955|S3B1_YEAST U2 snRNP component HSH155 Length = 971 Score = 241 bits (616), Expect = 1e-63 Identities = 114/213 (53%), Positives = 152/213 (71%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181 IA+A+GPHDVL LLNNLKVQERQ RVCT VAI IVA+ C P+ VLP +MNE+ P+ NV Sbjct: 753 IAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNV 812 Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361 QNGVLK++SFMFEYIG M+KDYIY + PLLEDAL DRDLVHRQTA + + H+AL G G Sbjct: 813 QNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALNCSGTG 872 Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLCHPARKITD 541 EDA +HL+N + PN+ ETSPH + ++ +E++ + G + Y+ GL HPA+ + Sbjct: 873 HEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPAKNVRK 932 Query: 542 MMCKIYNALYIANQDGLVSGFPRIKNDNRNQYL 640 ++YN +Y+ QD +V +P + DN +Y+ Sbjct: 933 AFWRVYNNMYVMYQDAMVPFYP-VTPDNNEEYI 964
>sp|O84075|Y072_CHLTR Hypothetical zinc metalloprotease CT072 Length = 619 Score = 33.1 bits (74), Expect = 0.74 Identities = 21/67 (31%), Positives = 27/67 (40%), Gaps = 2/67 (2%) Frame = +2 Query: 434 QAFVQCVESMRVSCGSITVLPYVLQGL--CHPARKITDMMCKIYNALYIANQDGLVSGFP 607 Q V V RV G +T+ PY L C + +Y YI N DG V Sbjct: 275 QGKVVFVRQARVLAGDLTLTPYFKNELIDCQYEAGLKGKWASLYTLPYIINGDGFVESKV 334 Query: 608 RIKNDNR 628 ++ ND R Sbjct: 335 KLLNDER 341
>sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3) (JAB1-containing signalosome subunit 3) Length = 423 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/52 (28%), Positives = 25/52 (48%) Frame = +1 Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 573 ++S A +C +C + C F + P ++ CKEN YD ++ C Y Sbjct: 138 LTSIHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYY 186
>sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3) (JAB1-containing signalosome subunit 3) Length = 423 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/52 (28%), Positives = 25/52 (48%) Frame = +1 Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 573 ++S A +C +C + C F + P ++ CKEN YD ++ C Y Sbjct: 138 LTSVHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYY 186
>sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Signalosome subunit 3) Length = 423 Score = 32.0 bits (71), Expect = 1.7 Identities = 15/52 (28%), Positives = 25/52 (48%) Frame = +1 Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVPSCKENHRYDVQNLQCLIY 573 ++S A +C +C + C F + P ++ CKEN YD ++ C Y Sbjct: 138 LTSVHADLCQLCLLAKC---FKPAVPFLELDMMDICKENGAYDAKHFLCYYY 186
>sp|Q6FDP8|UPPP2_ACIAD Undecaprenyl-diphosphatase 2 (Undecaprenyl pyrophosphate phosphatase 2) (Bacitracin resistance protein 2) Length = 285 Score = 31.6 bits (70), Expect = 2.2 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Frame = +2 Query: 2 IAKAVGPHDVLATLLNNL-KVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLN 178 +A A+ +L L + L + Q+ R+ + + I V C PF F Sbjct: 129 MAAALAAAGILIILSSRLDRGQQGDIRLPSAMIIGAVQALCLPF-------RGFSRSGAT 181 Query: 179 VQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLV---HRQTAISAVGHMALG 346 + G+ +S + A+++ +A+A +L A+I ++LV H Q A + H+ALG Sbjct: 182 ISTGLFLGIS------RQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALG 234
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 89,773,167 Number of Sequences: 369166 Number of extensions: 1963368 Number of successful extensions: 4849 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4692 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4844 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6219306880 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)