Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_I12
(709 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceo... 354 1e-97
sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceo... 353 2e-97
sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceo... 353 3e-97
sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10 280 3e-75
sp|P49955|S3B1_YEAST U2 snRNP component HSH155 249 5e-66
sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Si... 32 1.3
sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Si... 32 1.3
sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Si... 32 1.3
sp|Q6FDP8|UPPP2_ACIAD Undecaprenyl-diphosphatase 2 (Undecap... 32 2.2
sp|P03193|UL52_EBV Helicase/primase complex protein (Probab... 30 4.8
>sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit)
Length = 1304
Score = 354 bits (908), Expect = 1e-97
Identities = 167/221 (75%), Positives = 195/221 (88%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181
IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV
Sbjct: 1084 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1143
Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361
QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G
Sbjct: 1144 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1203
Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLWHPARKIRD 541
CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL+HPARK+RD
Sbjct: 1204 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRD 1263
Query: 542 MMWKIYNALYIGNQDGLVSGFPRIKNDNRNQYLRYELQYKL 664
+ WKIYN++YIG+QD L++ +PRI ND++N Y+RYEL Y L
Sbjct: 1264 VYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYELDYIL 1304
>sp|O57683|SF3B1_XENLA Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit) (146 kDa nuclear protein)
Length = 1307
Score = 353 bits (906), Expect = 2e-97
Identities = 166/221 (75%), Positives = 194/221 (87%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181
IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV
Sbjct: 1087 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1146
Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361
QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G
Sbjct: 1147 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1206
Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLWHPARKIRD 541
CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G ++ Y LQGL+HPARK+RD
Sbjct: 1207 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMVQYCLQGLFHPARKVRD 1266
Query: 542 MMWKIYNALYIGNQDGLVSGFPRIKNDNRNQYLRYELQYKL 664
+ WKIYN++YIG+QD L++ +PRI ND +N Y+RYEL Y L
Sbjct: 1267 VYWKIYNSIYIGSQDALIAHYPRIYNDEKNTYIRYELDYTL 1307
>sp|Q99NB9|SF3B1_MOUSE Splicing factor 3B subunit 1 (Spliceosome associated protein 155)
(SAP 155) (SF3b155) (Pre-mRNA splicing factor SF3b 155
kDa subunit)
Length = 1304
Score = 353 bits (905), Expect = 3e-97
Identities = 166/221 (75%), Positives = 195/221 (88%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181
IAKA+GPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLP LMNE+RVP+LNV
Sbjct: 1084 IAKAIGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRVPELNV 1143
Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361
QNGVLKSLSF+FEYIGEM KDYIYAV PLLEDAL+DRDLVHRQTA + V HM+LGVYG+G
Sbjct: 1144 QNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFG 1203
Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLWHPARKIRD 541
CED+L HLLN VWPNV ETSPH++QA + +E +RV+ G +L Y LQGL+HPARK+RD
Sbjct: 1204 CEDSLNHLLNYVWPNVFETSPHVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRD 1263
Query: 542 MMWKIYNALYIGNQDGLVSGFPRIKNDNRNQYLRYELQYKL 664
+ WKIYN++YIG+QD L++ +PRI ND++N Y+RY+L Y L
Sbjct: 1264 VYWKIYNSIYIGSQDALIAHYPRIYNDDKNTYIRYDLDYIL 1304
>sp|Q10178|SF3B1_SCHPO U2 snRNP component prp10
Length = 1188
Score = 280 bits (716), Expect = 3e-75
Identities = 127/212 (59%), Positives = 167/212 (78%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181
I+KA+GP DVLATLLNNLKVQERQNRVCTTVAIAIVAETC PFTV+P LM ++R P++NV
Sbjct: 968 ISKAIGPQDVLATLLNNLKVQERQNRVCTTVAIAIVAETCMPFTVVPALMADYRTPEMNV 1027
Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361
QNGVLKSL+FMFEYIGE A+DY+YA+ PLL DAL+DRD VHRQTA S + H++LG G G
Sbjct: 1028 QNGVLKSLAFMFEYIGEQARDYVYAITPLLADALMDRDAVHRQTAASVIKHLSLGCVGLG 1087
Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLWHPARKIRD 541
EDA++HLLN +WPN+LE SPH++ A + ++ +R G ++ Y++QGL+HP+RK+R+
Sbjct: 1088 VEDAMIHLLNILWPNILEESPHVINAVREGIDGIRNCIGVGPIMAYLVQGLFHPSRKVRN 1147
Query: 542 MMWKIYNALYIGNQDGLVSGFPRIKNDNRNQY 637
W YN+ Y+ + D +V +P + +D N Y
Sbjct: 1148 TYWTSYNSAYVQSADAMVPYYPHVDDDQFNNY 1179
>sp|P49955|S3B1_YEAST U2 snRNP component HSH155
Length = 971
Score = 249 bits (636), Expect = 5e-66
Identities = 116/213 (54%), Positives = 155/213 (72%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLNV 181
IA+A+GPHDVL LLNNLKVQERQ RVCT VAI IVA+ C P+ VLP +MNE+ P+ NV
Sbjct: 753 IAEAIGPHDVLVALLNNLKVQERQLRVCTAVAIGIVAKVCGPYNVLPVIMNEYTTPETNV 812
Query: 182 QNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGVYGYG 361
QNGVLK++SFMFEYIG M+KDYIY + PLLEDAL DRDLVHRQTA + + H+AL G G
Sbjct: 813 QNGVLKAMSFMFEYIGNMSKDYIYFITPLLEDALTDRDLVHRQTASNVITHLALNCSGTG 872
Query: 362 CEDALVHLLNCVWPNVLETSPHIVQAFVQCVESMRVSCGSITVLPYVLQGLWHPARKIRD 541
EDA +HL+N + PN+ ETSPH + ++ +E++ + G + Y+ GL+HPA+ +R
Sbjct: 873 HEDAFIHLMNLLIPNIFETSPHAIMRILEGLEALSQALGPGLFMNYIWAGLFHPAKNVRK 932
Query: 542 MMWKIYNALYIGNQDGLVSGFPRIKNDNRNQYL 640
W++YN +Y+ QD +V +P + DN +Y+
Sbjct: 933 AFWRVYNNMYVMYQDAMVPFYP-VTPDNNEEYI 964
>sp|Q9UNS2|CSN3_HUMAN COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3)
(JAB1-containing signalosome subunit 3)
Length = 423
Score = 32.3 bits (72), Expect = 1.3
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +1
Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVASCKENQRYDVENLQCLIYW 576
++S A +C +C + C F + P ++ CKEN YD ++ C Y+
Sbjct: 138 LTSIHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYYY 187
>sp|O88543|CSN3_MOUSE COP9 signalosome complex subunit 3 (Signalosome subunit 3) (SGN3)
(JAB1-containing signalosome subunit 3)
Length = 423
Score = 32.3 bits (72), Expect = 1.3
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +1
Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVASCKENQRYDVENLQCLIYW 576
++S A +C +C + C F + P ++ CKEN YD ++ C Y+
Sbjct: 138 LTSVHADLCQLCLLAKC---FKPALPYLDVDMMDICKENGAYDAKHFLCYYYY 187
>sp|Q6P2U9|CSN3_BRARE COP9 signalosome complex subunit 3 (Signalosome subunit 3)
Length = 423
Score = 32.3 bits (72), Expect = 1.3
Identities = 15/53 (28%), Positives = 26/53 (49%)
Frame = +1
Query: 418 VSSYCASVCSMCRIYACLLWFNNSAPVCIARVVASCKENQRYDVENLQCLIYW 576
++S A +C +C + C F + P ++ CKEN YD ++ C Y+
Sbjct: 138 LTSVHADLCQLCLLAKC---FKPAVPFLELDMMDICKENGAYDAKHFLCYYYY 187
>sp|Q6FDP8|UPPP2_ACIAD Undecaprenyl-diphosphatase 2 (Undecaprenyl pyrophosphate
phosphatase 2) (Bacitracin resistance protein 2)
Length = 285
Score = 31.6 bits (70), Expect = 2.2
Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 4/119 (3%)
Frame = +2
Query: 2 IAKAVGPHDVLATLLNNL-KVQERQNRVCTTVAIAIVAETCSPFTVLPGLMNEFRVPDLN 178
+A A+ +L L + L + Q+ R+ + + I V C PF F
Sbjct: 129 MAAALAAAGILIILSSRLDRGQQGDIRLPSAMIIGAVQALCLPF-------RGFSRSGAT 181
Query: 179 VQNGVLKSLSFMFEYIGEMAKDYIYAVAPLLEDALIDRDLV---HRQTAISAVGHMALG 346
+ G+ +S + A+++ +A+A +L A+I ++LV H Q A + H+ALG
Sbjct: 182 ISTGLFLGIS------RQKAEEFSFALAVVLTPAVIVKELVRLLHAQHATTGATHLALG 234
>sp|P03193|UL52_EBV Helicase/primase complex protein (Probable DNA replication protein
BSLF1)
Length = 874
Score = 30.4 bits (67), Expect = 4.8
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Frame = +2
Query: 173 LNVQNGVLKSLSFMFEYIGEMA-KDYIYAVAPLLEDALIDRDLVHRQTAISAVGHMALGV 349
LN+QN + SL ++G A K + Y +A D LI R R+T V ++ +
Sbjct: 674 LNIQNLLHHSL-----HVGWPAPKTFCYHIADDGRDYLIQRT---RETLPPTVENVCAMI 725
Query: 350 YGYGCEDALVHLLNCVWPNVLET 418
G+ D + + +C+WP+++ T
Sbjct: 726 EGHLGLDLVAWVSSCIWPSLMST 748
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,769,815
Number of Sequences: 369166
Number of extensions: 1957889
Number of successful extensions: 4782
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4633
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4777
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6219306880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)